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The map label for this gene is insK [H]

Identifier: 238925090

GI number: 238925090

Start: 2606432

End: 2607232

Strand: Reverse

Name: insK [H]

Synonym: EUBREC_2743

Alternate gene names: 238925090

Gene position: 2607232-2606432 (Counterclockwise)

Preceding gene: 238925091

Following gene: 238925087

Centisome position: 75.58

GC content: 34.96

Gene sequence:

>801_bases
ATGCACATGGCTAGATCTACTTACTATTTTGAGATTAGCAGAAACGATGTTATTGCCGAACGCAATCAAGAAATACTAGA
AGAAATAAAAAGTGTTTTTGTTGAGAACAAGCGCAGGTATGGTGTAAGACGGGTTCACCAGGAACTTATTAATCGCGGGT
ATCAGGTGAACCATAAAAGAGTTCAGCGTCTTATGCATGAAGCAGGTCTAGCCGGAAAAAGGCCAAAGGAGAAATATCAT
TCTTATAAGGGTGAAGTTGGTAAGATTGCTGACAACATAATAGACAGGGATTTCAGTACAACTTTGCCTTTACAAAAATG
GATCACAGATGTATCACAGTTCAATTTTTCATGGGGAAAGTGTTATATTTCTCCAGTGCTAGATATGAATACAAATGAAA
TCATCTCATATGATTTATCCATGAGTCCTAATCTTGAACAGATAAAAAGAATGCTGAATAAAGCATTTGAAAAATTTCCT
TCAGTTGAAGGATTGATATTTCATTCAGATCAAGGCTGGCAGTATCAACATGCTTATTTTAGAAATGCTTTACAGGAACA
TGGCATTATACAATCCATGTCACGAAAAGGTAATTGTTATGATAATTGTATTATGGAGACATTCTTTGGACGATTAAAAA
ATGAAATGTATTATGGCTATGAAAAAAACTATTCTTCTTTCGAAGAATTTTCACAAGCGGTTGCAGAATATATAGATTAT
TATAATAACAAAAGAATTCAGGCAAAAACAAAATGGATGCCGCCTGTACAATACAGGGTGGCATCCATGTGTTCAGCCTA
G

Upstream 100 bases:

>100_bases
TGAGGCAAGAAAAATGGGCTGCGCAACTCAAGGCGAAAAAGCAGCAATCATCAAAAAACTCAGAGAAAACGGATACCAAT
TAAAATATCTCCTTAAAGCA

Downstream 100 bases:

>100_bases
TTCATAAATATGTGTCCAGGATTATGGGTACATATCATTATTGCACAGGGCTTTAATTTTATCTTAAAGAAATGGTCTTT
CTTAAAATGGGTATCTTACC

Product: putative transposase, IS861

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MHMARSTYYFEISRNDVIAERNQEILEEIKSVFVENKRRYGVRRVHQELINRGYQVNHKRVQRLMHEAGLAGKRPKEKYH
SYKGEVGKIADNIIDRDFSTTLPLQKWITDVSQFNFSWGKCYISPVLDMNTNEIISYDLSMSPNLEQIKRMLNKAFEKFP
SVEGLIFHSDQGWQYQHAYFRNALQEHGIIQSMSRKGNCYDNCIMETFFGRLKNEMYYGYEKNYSSFEEFSQAVAEYIDY
YNNKRIQAKTKWMPPVQYRVASMCSA

Sequences:

>Translated_266_residues
MHMARSTYYFEISRNDVIAERNQEILEEIKSVFVENKRRYGVRRVHQELINRGYQVNHKRVQRLMHEAGLAGKRPKEKYH
SYKGEVGKIADNIIDRDFSTTLPLQKWITDVSQFNFSWGKCYISPVLDMNTNEIISYDLSMSPNLEQIKRMLNKAFEKFP
SVEGLIFHSDQGWQYQHAYFRNALQEHGIIQSMSRKGNCYDNCIMETFFGRLKNEMYYGYEKNYSSFEEFSQAVAEYIDY
YNNKRIQAKTKWMPPVQYRVASMCSA
>Mature_266_residues
MHMARSTYYFEISRNDVIAERNQEILEEIKSVFVENKRRYGVRRVHQELINRGYQVNHKRVQRLMHEAGLAGKRPKEKYH
SYKGEVGKIADNIIDRDFSTTLPLQKWITDVSQFNFSWGKCYISPVLDMNTNEIISYDLSMSPNLEQIKRMLNKAFEKFP
SVEGLIFHSDQGWQYQHAYFRNALQEHGIIQSMSRKGNCYDNCIMETFFGRLKNEMYYGYEKNYSSFEEFSQAVAEYIDY
YNNKRIQAKTKWMPPVQYRVASMCSA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=223, Percent_Identity=30.4932735426009, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1789981, Length=260, Percent_Identity=45.7692307692308, Blast_Score=237, Evalue=7e-64,
Organism=Escherichia coli, GI1788405, Length=263, Percent_Identity=29.277566539924, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787263, Length=263, Percent_Identity=29.277566539924, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786753, Length=263, Percent_Identity=29.277566539924, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786570, Length=263, Percent_Identity=29.277566539924, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786490, Length=263, Percent_Identity=29.277566539924, Blast_Score=114, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31618; Mature: 31618

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHMARSTYYFEISRNDVIAERNQEILEEIKSVFVENKRRYGVRRVHQELINRGYQVNHKR
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VQRLMHEAGLAGKRPKEKYHSYKGEVGKIADNIIDRDFSTTLPLQKWITDVSQFNFSWGK
HHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCC
CYISPVLDMNTNEIISYDLSMSPNLEQIKRMLNKAFEKFPSVEGLIFHSDQGWQYQHAYF
EEECHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
RNALQEHGIIQSMSRKGNCYDNCIMETFFGRLKNEMYYGYEKNYSSFEEFSQAVAEYIDY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YNNKRIQAKTKWMPPVQYRVASMCSA
HCCCEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MHMARSTYYFEISRNDVIAERNQEILEEIKSVFVENKRRYGVRRVHQELINRGYQVNHKR
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VQRLMHEAGLAGKRPKEKYHSYKGEVGKIADNIIDRDFSTTLPLQKWITDVSQFNFSWGK
HHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCC
CYISPVLDMNTNEIISYDLSMSPNLEQIKRMLNKAFEKFPSVEGLIFHSDQGWQYQHAYF
EEECHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
RNALQEHGIIQSMSRKGNCYDNCIMETFFGRLKNEMYYGYEKNYSSFEEFSQAVAEYIDY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YNNKRIQAKTKWMPPVQYRVASMCSA
HCCCEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]