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The map label for this gene is lysA [H]

Identifier: 238925013

GI number: 238925013

Start: 2540471

End: 2541760

Strand: Reverse

Name: lysA [H]

Synonym: EUBREC_2664

Alternate gene names: 238925013

Gene position: 2541760-2540471 (Counterclockwise)

Preceding gene: 238925014

Following gene: 238925012

Centisome position: 73.68

GC content: 43.8

Gene sequence:

>1290_bases
ATGAGACAGACACCGTACTATGTATTTGATACGGACGAGTTTGCAAAGAGAGCAGCCATGATAAGGGCTGCTCTTGATTG
TAAAGGAGGACGTAGGATACCGCTTTGCTTTTCGATAAAGGCAAACCCATTTCTGCTTCACAGGCTGCCGGAGGGCTTAG
ACCATGTGGAGGTGTGCAGCCCGGGAGAGCTTGAGATATGTATAGCACTGGGCGTGAAGCCGGAGAGCATCATTTATTCA
GGTGTGATGAAGGAAAAATGCGATATAGAGCGAGCAGTTTCATATGGCGCCGGCATACTGACCTGTGAAAGCATAAGACA
TGCGGCGCTGATATCAGAAGTGATGATTGAATGTATACAGGAAGGTGCGCATGAAGCCGAGTTTGCCGAAACGAAAGCAC
AGGTCATACTTCGCCTGACAAGTGGCAACCAGTTTGGCATGTCGCTTGAGGATATTGAATATATCATTTCGCATCCGGAT
GAGTTTAAGGGCATCACGGTAATAGGCATTCACTACTATTCCGGCACACAGAAGAGTCTTCGCAAAATAAATAAGGACTT
GGAAAAAATAAAGTCTGCACTGACCGGATTAAAAGAAAAATACGGCTTTGAGCCACAGCTTGTAGAGTATGGCCCGGGAC
TTTGCGTGGAGTATTTCGAGGATGACTGGCAGGAAAAGGAAAAACAATCACTTGATGAGGCAGCAGAGGTGCTTAGAGAA
TTTGCCGAGGAATATCCGCTTGGCATTGAGATGGGACGTTTCCTTGCAGCCTCATGCGGTAAATATTACACACAGGTAAA
GGACATTAAATCGACAGGCGATGCCAACTATGCGATTCTGGATGGAGGAATCCACCATCTGAATTACTTTGGGCAGAGGA
TGGCAATGCAGGTGCCGCCGATTAAGGTGTTTGATGGTATTGAATGGGAACTTGAAAAATCATCTGATGTATGTAGAGTA
CTTGGTATGGTCGGATATGAATGTATGAACGATATTATTAATAAAAATATGCAGAAAGCAAATGATTGTGAGGACTATAC
TTTGTGTGGAAGTTTATGTACAGTTGCAGATGTCATGGTGCGTGAAGTTGTCTTACCAAGACTGGAAATTGATAATATTA
TAGAATTTGGCCATTGTGGAGCATATTCGGTAACGGAAGCTCCGGTATTGTTCCTGTCAAGAAAATTACCGGCTGTATAT
GCATATTCAAAGCAAAAAGGTTTTGAATTGCTGAGAGGCTATGTGGCTGCATCGGATATAAACAGAGCACATATGTTTGA
CTGCATTTAA

Upstream 100 bases:

>100_bases
TTGACATCACAATCAGACCAAAGGATCTGGTTCCTGAGAATTTCAACTCAGTTGATGCAATCGAGAAGCTTGTGAAAGAG
CTTGTGGAGGAATAAAGCAT

Downstream 100 bases:

>100_bases
TTTAATAGAAATCTCGTGGATTAATAAGAACCACGAGATTTTTGTTTTAATATATATAATTCAGGATAATTCAGGCAATA
ATTCAGGCTCATTAATATTA

Product: putative diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MRQTPYYVFDTDEFAKRAAMIRAALDCKGGRRIPLCFSIKANPFLLHRLPEGLDHVEVCSPGELEICIALGVKPESIIYS
GVMKEKCDIERAVSYGAGILTCESIRHAALISEVMIECIQEGAHEAEFAETKAQVILRLTSGNQFGMSLEDIEYIISHPD
EFKGITVIGIHYYSGTQKSLRKINKDLEKIKSALTGLKEKYGFEPQLVEYGPGLCVEYFEDDWQEKEKQSLDEAAEVLRE
FAEEYPLGIEMGRFLAASCGKYYTQVKDIKSTGDANYAILDGGIHHLNYFGQRMAMQVPPIKVFDGIEWELEKSSDVCRV
LGMVGYECMNDIINKNMQKANDCEDYTLCGSLCTVADVMVREVVLPRLEIDNIIEFGHCGAYSVTEAPVLFLSRKLPAVY
AYSKQKGFELLRGYVAASDINRAHMFDCI

Sequences:

>Translated_429_residues
MRQTPYYVFDTDEFAKRAAMIRAALDCKGGRRIPLCFSIKANPFLLHRLPEGLDHVEVCSPGELEICIALGVKPESIIYS
GVMKEKCDIERAVSYGAGILTCESIRHAALISEVMIECIQEGAHEAEFAETKAQVILRLTSGNQFGMSLEDIEYIISHPD
EFKGITVIGIHYYSGTQKSLRKINKDLEKIKSALTGLKEKYGFEPQLVEYGPGLCVEYFEDDWQEKEKQSLDEAAEVLRE
FAEEYPLGIEMGRFLAASCGKYYTQVKDIKSTGDANYAILDGGIHHLNYFGQRMAMQVPPIKVFDGIEWELEKSSDVCRV
LGMVGYECMNDIINKNMQKANDCEDYTLCGSLCTVADVMVREVVLPRLEIDNIIEFGHCGAYSVTEAPVLFLSRKLPAVY
AYSKQKGFELLRGYVAASDINRAHMFDCI
>Mature_429_residues
MRQTPYYVFDTDEFAKRAAMIRAALDCKGGRRIPLCFSIKANPFLLHRLPEGLDHVEVCSPGELEICIALGVKPESIIYS
GVMKEKCDIERAVSYGAGILTCESIRHAALISEVMIECIQEGAHEAEFAETKAQVILRLTSGNQFGMSLEDIEYIISHPD
EFKGITVIGIHYYSGTQKSLRKINKDLEKIKSALTGLKEKYGFEPQLVEYGPGLCVEYFEDDWQEKEKQSLDEAAEVLRE
FAEEYPLGIEMGRFLAASCGKYYTQVKDIKSTGDANYAILDGGIHHLNYFGQRMAMQVPPIKVFDGIEWELEKSSDVCRV
LGMVGYECMNDIINKNMQKANDCEDYTLCGSLCTVADVMVREVVLPRLEIDNIIEFGHCGAYSVTEAPVLFLSRKLPAVY
AYSKQKGFELLRGYVAASDINRAHMFDCI

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 48179; Mature: 48179

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQTPYYVFDTDEFAKRAAMIRAALDCKGGRRIPLCFSIKANPFLLHRLPEGLDHVEVCS
CCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHCCCCCCCCCCCC
PGELEICIALGVKPESIIYSGVMKEKCDIERAVSYGAGILTCESIRHAALISEVMIECIQ
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHH
EGAHEAEFAETKAQVILRLTSGNQFGMSLEDIEYIISHPDEFKGITVIGIHYYSGTQKSL
CCCCHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHCCCCCCCCEEEEEEEEECCCHHHH
RKINKDLEKIKSALTGLKEKYGFEPQLVEYGPGLCVEYFEDDWQEKEKQSLDEAAEVLRE
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FAEEYPLGIEMGRFLAASCGKYYTQVKDIKSTGDANYAILDGGIHHLNYFGQRMAMQVPP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCC
IKVFDGIEWELEKSSDVCRVLGMVGYECMNDIINKNMQKANDCEDYTLCGSLCTVADVMV
EEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHH
REVVLPRLEIDNIIEFGHCGAYSVTEAPVLFLSRKLPAVYAYSKQKGFELLRGYVAASDI
HHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHCC
NRAHMFDCI
CHHHHCCCC
>Mature Secondary Structure
MRQTPYYVFDTDEFAKRAAMIRAALDCKGGRRIPLCFSIKANPFLLHRLPEGLDHVEVCS
CCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHCCCCCCCCCCCC
PGELEICIALGVKPESIIYSGVMKEKCDIERAVSYGAGILTCESIRHAALISEVMIECIQ
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHH
EGAHEAEFAETKAQVILRLTSGNQFGMSLEDIEYIISHPDEFKGITVIGIHYYSGTQKSL
CCCCHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHCCCCCCCCEEEEEEEEECCCHHHH
RKINKDLEKIKSALTGLKEKYGFEPQLVEYGPGLCVEYFEDDWQEKEKQSLDEAAEVLRE
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FAEEYPLGIEMGRFLAASCGKYYTQVKDIKSTGDANYAILDGGIHHLNYFGQRMAMQVPP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCC
IKVFDGIEWELEKSSDVCRVLGMVGYECMNDIINKNMQKANDCEDYTLCGSLCTVADVMV
EEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHH
REVVLPRLEIDNIIEFGHCGAYSVTEAPVLFLSRKLPAVYAYSKQKGFELLRGYVAASDI
HHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHCC
NRAHMFDCI
CHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA