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The map label for this gene is caiT [H]

Identifier: 238924954

GI number: 238924954

Start: 2481128

End: 2482651

Strand: Reverse

Name: caiT [H]

Synonym: EUBREC_2605

Alternate gene names: 238924954

Gene position: 2482651-2481128 (Counterclockwise)

Preceding gene: 238924955

Following gene: 238924953

Centisome position: 71.97

GC content: 36.48

Gene sequence:

>1524_bases
ATGAAAGAGAAAAAAATTGATTGGATTATTACACTTGTGCCATTAGCAATAATTGTGGCATTGTGTATTCTATTTTTTGC
ATTACCTGAGCAGTCAAATGCCATACTCAGTCAGGTAAGATTTTTCTTTGGAGATACGTTTGGCATTTATTACCTGATTA
TAGGTTTAGGAATATTTTTGATATCTATATTTATAGCTGGTTCGAAGTATGGAGATATTGTTCTTGGAGAGCCGGATGAA
AAACCAAAGTACTCATTCTTTTCATGGGGATGTATGATGTTCACATGTGGTCTGGCAGCAGATATTTTATTCTACTCATT
TTCTGAGTGGATTATGTATGCAACAAATCCACACATTAAGGAGCTTGGAAGTATACAGGAATGGGCCGGTGTATTTCCTC
TGTTTCACTGGAGCTTTATTCCGTGGGCATTTTATCTTGTTTTAGCAGTTGCATTTGGTTTTATGCTTCATGTAAGGAAA
AGAAACCGTCAGAAATATTCGGAAGCATGCAGACCTGTTCTTGGAAAACACACAGATGGTTTTGCAGGACGTATTATAGA
CCTGTTAGCTGTATTTGCACTTTTAGCAGGAACAGCAACCACATTTAGTGTTGCAACACCTCTTATGGCAACAATTATTG
GAGATGTGTTCCATATATCGCTTAGCAGAACAGCAATCAATATCATTATCCTTATAATTACATGTATAGTTTATACATAT
TCATTATTACATGGATTTAAGGGAATAAGCATTTTGGCAAAAGTCTGTATCTATTTCTTCTTTGGACTGCTTGCTATTGT
ACTGCTGTTTGGCGGTGAAACAAGATATATTCTTGAGACCGGATTGTCATCTCTTGGCACTATGGTGCAGAATTTTATAG
GATTATCTACGTATACCGATCCATTACGTAAAACCAACTTCCCACAGGACTGGACTATATATTACTGGGCTTACTGGATG
GTATGGTGTGTAGCAGCTCCTTTCTTTATTGGAAATATATCAAGAGGCAGAACTATCAGACAGACAATTCTTGGAGGATA
TGGATTTGGTGTTGGCTCTACGCTCATCAGCTTTATCATCTTAGGTAACTATTCAATGGGAAAACAGATGTCAGGAGCAG
CAGATTTTATTGCGCAGTACAACAAGAGTGGCGATTTATATGAGTTGATAGTTACTATTCTTAAGACATTGCCATGTGCA
CCTTTGATAATGATAATAGTTTTAGTGACAATGATTGCTTTTTATGCTACATCATTTGATTCTATTGCTTTAACTGTATC
ATGTTACAGCTATAGGAAATTAGGTGAGGATGAGCAGCCGCACAAACTCATTCAGCTGATGTGGTGCATACTGCTTATAC
TTTTACCAATTGCTCTGTTATTTGCTGAGAGCTCTATGAGTAACTTGCAGTCTGTAAGTATAGTTGCTGCATTTCCGATA
GGCATAGTTATTGTTTTGATAACAATCAGCTTTATGAAGGATGCGAAGAAATATATGGGTGAATTAAAGAATAAACAGAA
ATAA

Upstream 100 bases:

>100_bases
TTATCCCAGGTGTCTCAGATCATCTATAAATTTATAGAAAGGATAAGTGCATAACCATCATTTCTACTGGCTATACACTT
ATTATACGAGGATTAGTATT

Downstream 100 bases:

>100_bases
AATAGTTCAATATATGTGTAAGAATGCTTCGCTACATGGTAGTAGGAGCATTCTTTTTTCGCTTACGTCCCTTACACTGT
GGCGGAAATGTTGTTCAAAT

Product: choline/carnitine/betaine transporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MKEKKIDWIITLVPLAIIVALCILFFALPEQSNAILSQVRFFFGDTFGIYYLIIGLGIFLISIFIAGSKYGDIVLGEPDE
KPKYSFFSWGCMMFTCGLAADILFYSFSEWIMYATNPHIKELGSIQEWAGVFPLFHWSFIPWAFYLVLAVAFGFMLHVRK
RNRQKYSEACRPVLGKHTDGFAGRIIDLLAVFALLAGTATTFSVATPLMATIIGDVFHISLSRTAINIIILIITCIVYTY
SLLHGFKGISILAKVCIYFFFGLLAIVLLFGGETRYILETGLSSLGTMVQNFIGLSTYTDPLRKTNFPQDWTIYYWAYWM
VWCVAAPFFIGNISRGRTIRQTILGGYGFGVGSTLISFIILGNYSMGKQMSGAADFIAQYNKSGDLYELIVTILKTLPCA
PLIMIIVLVTMIAFYATSFDSIALTVSCYSYRKLGEDEQPHKLIQLMWCILLILLPIALLFAESSMSNLQSVSIVAAFPI
GIVIVLITISFMKDAKKYMGELKNKQK

Sequences:

>Translated_507_residues
MKEKKIDWIITLVPLAIIVALCILFFALPEQSNAILSQVRFFFGDTFGIYYLIIGLGIFLISIFIAGSKYGDIVLGEPDE
KPKYSFFSWGCMMFTCGLAADILFYSFSEWIMYATNPHIKELGSIQEWAGVFPLFHWSFIPWAFYLVLAVAFGFMLHVRK
RNRQKYSEACRPVLGKHTDGFAGRIIDLLAVFALLAGTATTFSVATPLMATIIGDVFHISLSRTAINIIILIITCIVYTY
SLLHGFKGISILAKVCIYFFFGLLAIVLLFGGETRYILETGLSSLGTMVQNFIGLSTYTDPLRKTNFPQDWTIYYWAYWM
VWCVAAPFFIGNISRGRTIRQTILGGYGFGVGSTLISFIILGNYSMGKQMSGAADFIAQYNKSGDLYELIVTILKTLPCA
PLIMIIVLVTMIAFYATSFDSIALTVSCYSYRKLGEDEQPHKLIQLMWCILLILLPIALLFAESSMSNLQSVSIVAAFPI
GIVIVLITISFMKDAKKYMGELKNKQK
>Mature_507_residues
MKEKKIDWIITLVPLAIIVALCILFFALPEQSNAILSQVRFFFGDTFGIYYLIIGLGIFLISIFIAGSKYGDIVLGEPDE
KPKYSFFSWGCMMFTCGLAADILFYSFSEWIMYATNPHIKELGSIQEWAGVFPLFHWSFIPWAFYLVLAVAFGFMLHVRK
RNRQKYSEACRPVLGKHTDGFAGRIIDLLAVFALLAGTATTFSVATPLMATIIGDVFHISLSRTAINIIILIITCIVYTY
SLLHGFKGISILAKVCIYFFFGLLAIVLLFGGETRYILETGLSSLGTMVQNFIGLSTYTDPLRKTNFPQDWTIYYWAYWM
VWCVAAPFFIGNISRGRTIRQTILGGYGFGVGSTLISFIILGNYSMGKQMSGAADFIAQYNKSGDLYELIVTILKTLPCA
PLIMIIVLVTMIAFYATSFDSIALTVSCYSYRKLGEDEQPHKLIQLMWCILLILLPIALLFAESSMSNLQSVSIVAAFPI
GIVIVLITISFMKDAKKYMGELKNKQK

Specific function: Catalyzes the exchange of L-carnitine for gamma- butyrobetaine and related betaines [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788102, Length=450, Percent_Identity=26.4444444444444, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1786224, Length=504, Percent_Identity=29.1666666666667, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1786506, Length=469, Percent_Identity=27.2921108742004, Blast_Score=172, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 56803; Mature: 56803

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKKIDWIITLVPLAIIVALCILFFALPEQSNAILSQVRFFFGDTFGIYYLIIGLGIFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ISIFIAGSKYGDIVLGEPDEKPKYSFFSWGCMMFTCGLAADILFYSFSEWIMYATNPHIK
HHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHH
ELGSIQEWAGVFPLFHWSFIPWAFYLVLAVAFGFMLHVRKRNRQKYSEACRPVLGKHTDG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FAGRIIDLLAVFALLAGTATTFSVATPLMATIIGDVFHISLSRTAINIIILIITCIVYTY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLHGFKGISILAKVCIYFFFGLLAIVLLFGGETRYILETGLSSLGTMVQNFIGLSTYTD
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PLRKTNFPQDWTIYYWAYWMVWCVAAPFFIGNISRGRTIRQTILGGYGFGVGSTLISFII
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHH
LGNYSMGKQMSGAADFIAQYNKSGDLYELIVTILKTLPCAPLIMIIVLVTMIAFYATSFD
HCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
SIALTVSCYSYRKLGEDEQPHKLIQLMWCILLILLPIALLFAESSMSNLQSVSIVAAFPI
CCEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVIVLITISFMKDAKKYMGELKNKQK
HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKEKKIDWIITLVPLAIIVALCILFFALPEQSNAILSQVRFFFGDTFGIYYLIIGLGIFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ISIFIAGSKYGDIVLGEPDEKPKYSFFSWGCMMFTCGLAADILFYSFSEWIMYATNPHIK
HHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHH
ELGSIQEWAGVFPLFHWSFIPWAFYLVLAVAFGFMLHVRKRNRQKYSEACRPVLGKHTDG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FAGRIIDLLAVFALLAGTATTFSVATPLMATIIGDVFHISLSRTAINIIILIITCIVYTY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLHGFKGISILAKVCIYFFFGLLAIVLLFGGETRYILETGLSSLGTMVQNFIGLSTYTD
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PLRKTNFPQDWTIYYWAYWMVWCVAAPFFIGNISRGRTIRQTILGGYGFGVGSTLISFII
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHH
LGNYSMGKQMSGAADFIAQYNKSGDLYELIVTILKTLPCAPLIMIIVLVTMIAFYATSFD
HCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
SIALTVSCYSYRKLGEDEQPHKLIQLMWCILLILLPIALLFAESSMSNLQSVSIVAAFPI
CCEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVIVLITISFMKDAKKYMGELKNKQK
HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA