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The map label for this gene is xylR [H]

Identifier: 238924934

GI number: 238924934

Start: 2456933

End: 2458171

Strand: Reverse

Name: xylR [H]

Synonym: EUBREC_2585

Alternate gene names: 238924934

Gene position: 2458171-2456933 (Counterclockwise)

Preceding gene: 238924935

Following gene: 238924933

Centisome position: 71.26

GC content: 39.95

Gene sequence:

>1239_bases
ATGGTTAAAACCGGAATTTCCCTTGATAGTGTAAAAAACAATAATAAATCTCAGATACTTAAGATACTGCAGAAAAACGG
CGCAATGTCAAGGAAGGATATTGCCAATCAGATAGGACTCACACCGGCGGCTGTGACCATGCTGTGCAATGATATGATGG
AAGCTCACATGATACTTGAAAAGGGTGAGATGAAGGAGCAGAAGAGAGCGGGCCGTAAGAAGGTGCTTGTGGATATCAAT
TATGATTTTAAGTATATAGTATCTGTAAATATTGAGGCTGTAGACACGAGCATTACAGTTACCAATATCAGGGGAAATGT
GCTTGTTGAAACTAAGGTACATACCCGGACGGACATTGAACCACAGCTGTTTTTAGAAGAACTGGCAAAGGAAATAAAGC
TTCAGCTTTGGGAAAAGGAACTTAAGCTGTCAGATATTCTTGGAATCGGAATATGTGTTCCGGGAATAGTTGACAGGAAT
AATGGCATCAGTATACACGCTTATGGCATATGGAACAATCAAGTAAAAATAAGAGAAATACTTGAAAAACAGATTCAGTG
TCCGGTAATACTTGAAAACAACGTCAAAGCATTTGCGGAAGCCGAAATGCTTTATGGTGTCGGAAAATATGGAAACAATA
TTGTTTTTATTAAGTGGGGCCCGGGTGTCGGCTCTGCGATAGTTGTGGACAATAAGCTATATGAGGGCAATCAGCACAAC
GCAGCAGAAATAGGACACTACATCATAGAGCCTGATGGACTTAAGTGCAGATGTGGCAGACAGGGCTGTCTTGAAACAAG
AGTATCCATGTTTGCCCTGTGTGACCGCATAAAGGAGATATATTCCAAGGAAAATACCCCTGTGCTATACGAAGAAACAG
CCGGTGATAAAAATCTTATAACAAGAGAGCTCTTGACTTCGTGGGTAGAAAATGAGGGCAACGGCTACATAACAAGGATG
GATAAGACAATTTCTGAGATACTTGTTGGAGCAATAGAACGAATGGCACGTGTCGCTGTAAATGTGTTGACTATTCTGGC
TCCGGATTGCACGATAGTGTTTGGTTCAATGTTTGAAAATACAAGTATATATAAGCTTTTTATACAGTACTGCACAAAAT
ATGATGAAAACTATACTGACAAGCTTATCAGCCGTTCACACTTGAGCGATAAGATGGCATATATAGGCGGAACAGCACTT
ATAGCGAGCACTTATTTCTTTGAAAGTAAAAATTTATAA

Upstream 100 bases:

>100_bases
CGGTGCATATAGGTGATGTACTGCTAAGTGATGCTGCTGCAACCGGTGTGGATATAGTTGCAACAAAGAATGTTGAAGCA
TAAATAAGTAGCATGAATTA

Downstream 100 bases:

>100_bases
TAAAGAAAAAATGAAGAAATCTTATTGATATTTTCTTTATTGTTGCATATACTATAAGTAAGAAAGGAGTGTTGTATATG
TCACAGTCAGTTAATGTTAA

Product: putative NAGC-like transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MVKTGISLDSVKNNNKSQILKILQKNGAMSRKDIANQIGLTPAAVTMLCNDMMEAHMILEKGEMKEQKRAGRKKVLVDIN
YDFKYIVSVNIEAVDTSITVTNIRGNVLVETKVHTRTDIEPQLFLEELAKEIKLQLWEKELKLSDILGIGICVPGIVDRN
NGISIHAYGIWNNQVKIREILEKQIQCPVILENNVKAFAEAEMLYGVGKYGNNIVFIKWGPGVGSAIVVDNKLYEGNQHN
AAEIGHYIIEPDGLKCRCGRQGCLETRVSMFALCDRIKEIYSKENTPVLYEETAGDKNLITRELLTSWVENEGNGYITRM
DKTISEILVGAIERMARVAVNVLTILAPDCTIVFGSMFENTSIYKLFIQYCTKYDENYTDKLISRSHLSDKMAYIGGTAL
IASTYFFESKNL

Sequences:

>Translated_412_residues
MVKTGISLDSVKNNNKSQILKILQKNGAMSRKDIANQIGLTPAAVTMLCNDMMEAHMILEKGEMKEQKRAGRKKVLVDIN
YDFKYIVSVNIEAVDTSITVTNIRGNVLVETKVHTRTDIEPQLFLEELAKEIKLQLWEKELKLSDILGIGICVPGIVDRN
NGISIHAYGIWNNQVKIREILEKQIQCPVILENNVKAFAEAEMLYGVGKYGNNIVFIKWGPGVGSAIVVDNKLYEGNQHN
AAEIGHYIIEPDGLKCRCGRQGCLETRVSMFALCDRIKEIYSKENTPVLYEETAGDKNLITRELLTSWVENEGNGYITRM
DKTISEILVGAIERMARVAVNVLTILAPDCTIVFGSMFENTSIYKLFIQYCTKYDENYTDKLISRSHLSDKMAYIGGTAL
IASTYFFESKNL
>Mature_412_residues
MVKTGISLDSVKNNNKSQILKILQKNGAMSRKDIANQIGLTPAAVTMLCNDMMEAHMILEKGEMKEQKRAGRKKVLVDIN
YDFKYIVSVNIEAVDTSITVTNIRGNVLVETKVHTRTDIEPQLFLEELAKEIKLQLWEKELKLSDILGIGICVPGIVDRN
NGISIHAYGIWNNQVKIREILEKQIQCPVILENNVKAFAEAEMLYGVGKYGNNIVFIKWGPGVGSAIVVDNKLYEGNQHN
AAEIGHYIIEPDGLKCRCGRQGCLETRVSMFALCDRIKEIYSKENTPVLYEETAGDKNLITRELLTSWVENEGNGYITRM
DKTISEILVGAIERMARVAVNVLTILAPDCTIVFGSMFENTSIYKLFIQYCTKYDENYTDKLISRSHLSDKMAYIGGTAL
IASTYFFESKNL

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=251, Percent_Identity=27.8884462151394, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI298566315, Length=251, Percent_Identity=27.8884462151394, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI190014632, Length=251, Percent_Identity=27.8884462151394, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4885285, Length=251, Percent_Identity=27.8884462151394, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1787878, Length=267, Percent_Identity=26.2172284644195, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1786891, Length=272, Percent_Identity=26.1029411764706, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87082127, Length=374, Percent_Identity=22.4598930481283, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 46328; Mature: 46328

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKTGISLDSVKNNNKSQILKILQKNGAMSRKDIANQIGLTPAAVTMLCNDMMEAHMILE
CCCCCCCHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KGEMKEQKRAGRKKVLVDINYDFKYIVSVNIEAVDTSITVTNIRGNVLVETKVHTRTDIE
CCCHHHHHHCCCEEEEEEECCCEEEEEEEEEEEEEEEEEEEEECCCEEEEEEECCCCCCC
PQLFLEELAKEIKLQLWEKELKLSDILGIGICVPGIVDRNNGISIHAYGIWNNQVKIREI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCCEEEEEEEEECCCCHHHHH
LEKQIQCPVILENNVKAFAEAEMLYGVGKYGNNIVFIKWGPGVGSAIVVDNKLYEGNQHN
HHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECEEECCCCCC
AAEIGHYIIEPDGLKCRCGRQGCLETRVSMFALCDRIKEIYSKENTPVLYEETAGDKNLI
HHHHCCEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHH
TRELLTSWVENEGNGYITRMDKTISEILVGAIERMARVAVNVLTILAPDCTIVFGSMFEN
HHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHCC
TSIYKLFIQYCTKYDENYTDKLISRSHLSDKMAYIGGTALIASTYFFESKNL
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEECCCC
>Mature Secondary Structure
MVKTGISLDSVKNNNKSQILKILQKNGAMSRKDIANQIGLTPAAVTMLCNDMMEAHMILE
CCCCCCCHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KGEMKEQKRAGRKKVLVDINYDFKYIVSVNIEAVDTSITVTNIRGNVLVETKVHTRTDIE
CCCHHHHHHCCCEEEEEEECCCEEEEEEEEEEEEEEEEEEEEECCCEEEEEEECCCCCCC
PQLFLEELAKEIKLQLWEKELKLSDILGIGICVPGIVDRNNGISIHAYGIWNNQVKIREI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCCEEEEEEEEECCCCHHHHH
LEKQIQCPVILENNVKAFAEAEMLYGVGKYGNNIVFIKWGPGVGSAIVVDNKLYEGNQHN
HHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECEEECCCCCC
AAEIGHYIIEPDGLKCRCGRQGCLETRVSMFALCDRIKEIYSKENTPVLYEETAGDKNLI
HHHHCCEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHH
TRELLTSWVENEGNGYITRMDKTISEILVGAIERMARVAVNVLTILAPDCTIVFGSMFEN
HHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHCC
TSIYKLFIQYCTKYDENYTDKLISRSHLSDKMAYIGGTALIASTYFFESKNL
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]