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The map label for this gene is yoeB [H]

Identifier: 238924932

GI number: 238924932

Start: 2456329

End: 2456589

Strand: Reverse

Name: yoeB [H]

Synonym: EUBREC_2583

Alternate gene names: 238924932

Gene position: 2456589-2456329 (Counterclockwise)

Preceding gene: 238924933

Following gene: 238924929

Centisome position: 71.21

GC content: 35.25

Gene sequence:

>261_bases
ATGAGGTTACTATGGGAAGATAGGGCATGGAGCGATTATTTATACTGGCAGACGCAGGATAAGAAAACACTGAAAAGAAT
TAATGGACTTATCAAGGATATTCAGCGAAGTACGTTTGAGGGTATAGGTAAACCGGAACCATTAAAGGAAAATCTTAGTG
GTATGTGGAGCAGACGCATTGATGACACTAATCGAATTGTTTATTATGAAAAAGATGAGATAATTTATATTGTTTCATGT
AAAGGTCATTATGATGATTGA

Upstream 100 bases:

>100_bases
TTTATTCTGATAGCAATATCCGTTATTTGGAAAATATCGTGCGCGATATTAAGGATGGCAAAGCTCACTTCGCAGAGCAT
GATTTGATAGAGGAGGACTA

Downstream 100 bases:

>100_bases
AAAATCATATTGACAAATCACCCAATGCACTTTAATATTGTAGAAAGAAACAGGCAAATATTTAAAGGCATAAGAAAGAG
GAGTACATGACGAAAGCTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Putative endoribonuclease YoeB; Putative mRNA interferase Yoeb [H]

Number of amino acids: Translated: 86; Mature: 86

Protein sequence:

>86_residues
MRLLWEDRAWSDYLYWQTQDKKTLKRINGLIKDIQRSTFEGIGKPEPLKENLSGMWSRRIDDTNRIVYYEKDEIIYIVSC
KGHYDD

Sequences:

>Translated_86_residues
MRLLWEDRAWSDYLYWQTQDKKTLKRINGLIKDIQRSTFEGIGKPEPLKENLSGMWSRRIDDTNRIVYYEKDEIIYIVSC
KGHYDD
>Mature_86_residues
MRLLWEDRAWSDYLYWQTQDKKTLKRINGLIKDIQRSTFEGIGKPEPLKENLSGMWSRRIDDTNRIVYYEKDEIIYIVSC
KGHYDD

Specific function: Part of a toxin-antitoxin (TA) module. It has been proposed to be an mRNA interferase but also an inhibitor of translation initiation. Has an in vitro RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides. YefM binds to the pro

COG id: COG4115

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YoeB family [H]

Homologues:

Organism=Escherichia coli, GI87082025, Length=84, Percent_Identity=55.952380952381, Blast_Score=107, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009614 [H]

Pfam domain/function: PF06769 Plasmid_Txe [H]

EC number: NA

Molecular weight: Translated: 10447; Mature: 10447

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLWEDRAWSDYLYWQTQDKKTLKRINGLIKDIQRSTFEGIGKPEPLKENLSGMWSRRI
CCCEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
DDTNRIVYYEKDEIIYIVSCKGHYDD
CCCCEEEEECCCCEEEEEECCCCCCC
>Mature Secondary Structure
MRLLWEDRAWSDYLYWQTQDKKTLKRINGLIKDIQRSTFEGIGKPEPLKENLSGMWSRRI
CCCEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
DDTNRIVYYEKDEIIYIVSCKGHYDD
CCCCEEEEECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]