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The map label for this gene is spoIIAB [H]

Identifier: 238924922

GI number: 238924922

Start: 2447102

End: 2447581

Strand: Reverse

Name: spoIIAB [H]

Synonym: EUBREC_2573

Alternate gene names: 238924922

Gene position: 2447581-2447102 (Counterclockwise)

Preceding gene: 238924923

Following gene: 238924921

Centisome position: 70.95

GC content: 43.75

Gene sequence:

>480_bases
ATGAACGCAGCAAAAACAAATCATATATCGCTTAGCTTTGATGCAATTTCAGAGAATGAGGCATTTGCGAGAATGACAGC
AGCCATGTTTATGGCACAATTAAACCCCACACTAGATGACGTGGAGGACGTAAAGACAGCAGTGTCAGAGGCGGTGACAA
ACGCAATTATCCATGGCTATGAGATGGGGGATGACAATATTTCATCCGGTCAGGCAGATCACCAGGCAGCAGAAGAAAAA
AGTTGTCCACAGGTACATATGAATTGCAGCTACATAGGCAGGGAGCTTTACATAGAAATATCAGATAGCGGAGTAGGCAT
ACAGGATGTGGCAAAAGCAATGGAACCGTTATACACATCCAAACCACAGCTTGACAGATCAGGCATGGGTTTTTCATTCA
TGGAAGCATTTATGGACGCGCTGACAGTTACATCAGAACCGGGACACGGAACAACAGTAAAGATGAAAAAAGTACTATGA

Upstream 100 bases:

>100_bases
AGAGTGGACAAGCTTTTGAAATGTGCCGGCATTTACACTATTGTACATAAGCTTTAAAACTGAATTAAATTAAAATATAA
TCAGACAGAAAGGGAGCATA

Downstream 100 bases:

>100_bases
AGAGTGACAAAATCAGCAGACTTGTCACAGAAAATATAAACCTGATTTATTTAGTTATGAAACGCTTTAGAAACAGAGGC
GTTGACCGGGAGGATTTATT

Product: putative anti-sigma regulatory factor, serine/threonine protein kinase

Products: NA

Alternate protein names: Stage II sporulation protein AB [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MNAAKTNHISLSFDAISENEAFARMTAAMFMAQLNPTLDDVEDVKTAVSEAVTNAIIHGYEMGDDNISSGQADHQAAEEK
SCPQVHMNCSYIGRELYIEISDSGVGIQDVAKAMEPLYTSKPQLDRSGMGFSFMEAFMDALTVTSEPGHGTTVKMKKVL

Sequences:

>Translated_159_residues
MNAAKTNHISLSFDAISENEAFARMTAAMFMAQLNPTLDDVEDVKTAVSEAVTNAIIHGYEMGDDNISSGQADHQAAEEK
SCPQVHMNCSYIGRELYIEISDSGVGIQDVAKAMEPLYTSKPQLDRSGMGFSFMEAFMDALTVTSEPGHGTTVKMKKVL
>Mature_159_residues
MNAAKTNHISLSFDAISENEAFARMTAAMFMAQLNPTLDDVEDVKTAVSEAVTNAIIHGYEMGDDNISSGQADHQAAEEK
SCPQVHMNCSYIGRELYIEISDSGVGIQDVAKAMEPLYTSKPQLDRSGMGFSFMEAFMDALTVTSEPGHGTTVKMKKVL

Specific function: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases si

COG id: COG2172

COG function: function code T; Anti-sigma regulatory factor (Ser/Thr protein kinase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anti-sigma-factor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010194
- InterPro:   IPR003594 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 17247; Mature: 17247

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
6.9 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAKTNHISLSFDAISENEAFARMTAAMFMAQLNPTLDDVEDVKTAVSEAVTNAIIHGY
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCE
EMGDDNISSGQADHQAAEEKSCPQVHMNCSYIGRELYIEISDSGVGIQDVAKAMEPLYTS
ECCCCCCCCCCCHHHHHHHCCCCEEECCCEEECEEEEEEECCCCCCHHHHHHHHHHHHCC
KPQLDRSGMGFSFMEAFMDALTVTSEPGHGTTVKMKKVL
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MNAAKTNHISLSFDAISENEAFARMTAAMFMAQLNPTLDDVEDVKTAVSEAVTNAIIHGY
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCE
EMGDDNISSGQADHQAAEEKSCPQVHMNCSYIGRELYIEISDSGVGIQDVAKAMEPLYTS
ECCCCCCCCCCCHHHHHHHCCCCEEECCCEEECEEEEEEECCCCCCHHHHHHHHHHHHCC
KPQLDRSGMGFSFMEAFMDALTVTSEPGHGTTVKMKKVL
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]