Click here to switch to the map view.

The map label for this gene is glnA [H]

Identifier: 238924892

GI number: 238924892

Start: 2416104

End: 2417435

Strand: Reverse

Name: glnA [H]

Synonym: EUBREC_2543

Alternate gene names: 238924892

Gene position: 2417435-2416104 (Counterclockwise)

Preceding gene: 238924893

Following gene: 238924891

Centisome position: 70.08

GC content: 44.74

Gene sequence:

>1332_bases
ATGGCAAAATACAGTAAGAATGATATTATCCGCATAGTGGATGAGGAGGATATTGAGTTTATCCGTTTACAGTTTACGGA
CATCTTTGGAACATTAAAAAATGTGGCAATTACAGCCAGCCAGCTTGAGAAGGCACTCGACAACAAGTGTATGTTCGACG
GCTCGTCAATAGAGGGCTTTGTGAGGATAGAGGAGTCAGATATGTATCTGCACCCGGATCTTGACACTTTTATGATTTTT
CCATGGAGACCACAGCAGGGCAAGGTCGCACGAATCATCTGTGATGTCTATATGGCAGATGGTACACCGTTTGAGGGAGA
CCCGCGCTATATATTAAAGAAGCAGATTGAAAAGGCAAAGCAGATGGGCTATATATTTAATGTAGGTCCGGAGTGTGAGT
TTTTCCTTTTCCACCTGGACGAGAACGGACAGCCTACCACCATCTCGCATGAGAGAGCAGGGTACTTTGACCTGGGACCA
AATGATTTGGGAGAAAACGCAAGAAGAGACATGGTTTTAACTCTTGAGGATATGGATTTTGAGATAGAGGCATCACATCA
TGAGGTGGCACCTGCACAGCATGAGATTGATTTCAAGTATGAGGAGGCACTTCATACCGCCGACAATATCATGACCTTTA
AGCTTGCTATAAAGACAATCGCAAAGCGGCACGGACTTTTTGCCAGCTTCATGCCAAAGCCAAAGCATGGTGTGAGCGGC
TCGGGAATGCATATCAACATGTCACTTTCAAAGGATGGTGTCAATATATTTGACAATGAGGAGGATGAGCTCGGACTCAG
CGAGGAGGCATACTACTTCATAGGCGGTATCATGAAGCATATGAAGGGCATGACGGTCATCACTAATCCAATCGTCAATT
CATATAAGCGCTTTGTGCCGGGATATGAGGCACCGATTTATATCACCTGGTCAGCTACAAACAGAAGTCCGCTTATCAGA
ATCCCTGCAGCAAGAGGTGAGGGAAGGAGAGTGGAGCTTAGAAACCCTGATCCTTCAGCAAATCCGTATCTGGTTCTGGC
ACTGTGCCTGGCAGCAGGAATTGACGGCATAAAGAACAAGATACAGCCGGATACAGAGCTTCGTGAGAATGTATTTGAGC
TCACAGAACAGGATAAAAAGAGACTCGGAATTGAATCACTTCCTGCTGATTTACATGAGGCGGTTGAGTGCCTTAAGTCA
GATGATTTTATCCGCGAGATACTGGGTGAACATATCTACGACAAATATATAGAGGCAAAAGAGGCAGAGTGGAACGATTA
CAGAGCTGCGGTTACCCAATGGGAAATAGATGAATATCTGTACAAATTTTAA

Upstream 100 bases:

>100_bases
AACCATCTGAATGTGACAATAGGCAGTGCTCTTGATTTGTTTGGCGGTGAGATGGAGTACGATAAGGTTATAGCTTTTTG
CAATAATAAGGAGATTTAAA

Downstream 100 bases:

>100_bases
AGGATGTAACAAACCGTGAATAATATTGTTATAGCATTTCCTAAAAAGGAAGTAGCCAATTCAATCAAAAAAATATTAGC
GCAGAGCGGTTATACAGTCA

Product: glutamine synthetase, type I

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MAKYSKNDIIRIVDEEDIEFIRLQFTDIFGTLKNVAITASQLEKALDNKCMFDGSSIEGFVRIEESDMYLHPDLDTFMIF
PWRPQQGKVARIICDVYMADGTPFEGDPRYILKKQIEKAKQMGYIFNVGPECEFFLFHLDENGQPTTISHERAGYFDLGP
NDLGENARRDMVLTLEDMDFEIEASHHEVAPAQHEIDFKYEEALHTADNIMTFKLAIKTIAKRHGLFASFMPKPKHGVSG
SGMHINMSLSKDGVNIFDNEEDELGLSEEAYYFIGGIMKHMKGMTVITNPIVNSYKRFVPGYEAPIYITWSATNRSPLIR
IPAARGEGRRVELRNPDPSANPYLVLALCLAAGIDGIKNKIQPDTELRENVFELTEQDKKRLGIESLPADLHEAVECLKS
DDFIREILGEHIYDKYIEAKEAEWNDYRAAVTQWEIDEYLYKF

Sequences:

>Translated_443_residues
MAKYSKNDIIRIVDEEDIEFIRLQFTDIFGTLKNVAITASQLEKALDNKCMFDGSSIEGFVRIEESDMYLHPDLDTFMIF
PWRPQQGKVARIICDVYMADGTPFEGDPRYILKKQIEKAKQMGYIFNVGPECEFFLFHLDENGQPTTISHERAGYFDLGP
NDLGENARRDMVLTLEDMDFEIEASHHEVAPAQHEIDFKYEEALHTADNIMTFKLAIKTIAKRHGLFASFMPKPKHGVSG
SGMHINMSLSKDGVNIFDNEEDELGLSEEAYYFIGGIMKHMKGMTVITNPIVNSYKRFVPGYEAPIYITWSATNRSPLIR
IPAARGEGRRVELRNPDPSANPYLVLALCLAAGIDGIKNKIQPDTELRENVFELTEQDKKRLGIESLPADLHEAVECLKS
DDFIREILGEHIYDKYIEAKEAEWNDYRAAVTQWEIDEYLYKF
>Mature_442_residues
AKYSKNDIIRIVDEEDIEFIRLQFTDIFGTLKNVAITASQLEKALDNKCMFDGSSIEGFVRIEESDMYLHPDLDTFMIFP
WRPQQGKVARIICDVYMADGTPFEGDPRYILKKQIEKAKQMGYIFNVGPECEFFLFHLDENGQPTTISHERAGYFDLGPN
DLGENARRDMVLTLEDMDFEIEASHHEVAPAQHEIDFKYEEALHTADNIMTFKLAIKTIAKRHGLFASFMPKPKHGVSGS
GMHINMSLSKDGVNIFDNEEDELGLSEEAYYFIGGIMKHMKGMTVITNPIVNSYKRFVPGYEAPIYITWSATNRSPLIRI
PAARGEGRRVELRNPDPSANPYLVLALCLAAGIDGIKNKIQPDTELRENVFELTEQDKKRLGIESLPADLHEAVECLKSD
DFIREILGEHIYDKYIEAKEAEWNDYRAAVTQWEIDEYLYKF

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=440, Percent_Identity=24.5454545454545, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI1790301, Length=473, Percent_Identity=38.0549682875264, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI87081870, Length=459, Percent_Identity=26.3616557734205, Blast_Score=141, Evalue=9e-35,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 50726; Mature: 50595

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00180 GLNA_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKYSKNDIIRIVDEEDIEFIRLQFTDIFGTLKNVAITASQLEKALDNKCMFDGSSIEGF
CCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHEEEHHHHHHHHCCCEEECCCCCCEE
VRIEESDMYLHPDLDTFMIFPWRPQQGKVARIICDVYMADGTPFEGDPRYILKKQIEKAK
EEEECCCEEECCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
QMGYIFNVGPECEFFLFHLDENGQPTTISHERAGYFDLGPNDLGENARRDMVLTLEDMDF
HCCEEEECCCCCEEEEEEECCCCCCCEECCCCCCEECCCCHHCCCCCCCCEEEEEECCCE
EIEASHHEVAPAQHEIDFKYEEALHTADNIMTFKLAIKTIAKRHGLFASFMPKPKHGVSG
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEHHHHHHHHHHHCCCHHHCCCCCCCCCCC
SGMHINMSLSKDGVNIFDNEEDELGLSEEAYYFIGGIMKHMKGMTVITNPIVNSYKRFVP
CCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCC
GYEAPIYITWSATNRSPLIRIPAARGEGRRVELRNPDPSANPYLVLALCLAAGIDGIKNK
CCCCCEEEEEECCCCCCEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCHHHHHC
IQPDTELRENVFELTEQDKKRLGIESLPADLHEAVECLKSDDFIREILGEHIYDKYIEAK
CCCCHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
EAEWNDYRAAVTQWEIDEYLYKF
CCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKYSKNDIIRIVDEEDIEFIRLQFTDIFGTLKNVAITASQLEKALDNKCMFDGSSIEGF
CCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHEEEHHHHHHHHCCCEEECCCCCCEE
VRIEESDMYLHPDLDTFMIFPWRPQQGKVARIICDVYMADGTPFEGDPRYILKKQIEKAK
EEEECCCEEECCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
QMGYIFNVGPECEFFLFHLDENGQPTTISHERAGYFDLGPNDLGENARRDMVLTLEDMDF
HCCEEEECCCCCEEEEEEECCCCCCCEECCCCCCEECCCCHHCCCCCCCCEEEEEECCCE
EIEASHHEVAPAQHEIDFKYEEALHTADNIMTFKLAIKTIAKRHGLFASFMPKPKHGVSG
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEHHHHHHHHHHHCCCHHHCCCCCCCCCCC
SGMHINMSLSKDGVNIFDNEEDELGLSEEAYYFIGGIMKHMKGMTVITNPIVNSYKRFVP
CCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCC
GYEAPIYITWSATNRSPLIRIPAARGEGRRVELRNPDPSANPYLVLALCLAAGIDGIKNK
CCCCCEEEEEECCCCCCEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCHHHHHC
IQPDTELRENVFELTEQDKKRLGIESLPADLHEAVECLKSDDFIREILGEHIYDKYIEAK
CCCCHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
EAEWNDYRAAVTQWEIDEYLYKF
CCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2891680; 1981087 [H]