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The map label for this gene is msmR [H]

Identifier: 238924310

GI number: 238924310

Start: 1839301

End: 1840140

Strand: Direct

Name: msmR [H]

Synonym: EUBREC_1950

Alternate gene names: 238924310

Gene position: 1839301-1840140 (Clockwise)

Preceding gene: 238924261

Following gene: 238924315

Centisome position: 53.32

GC content: 43.1

Gene sequence:

>840_bases
ATGAATAATAAATACAAAAATTCCTATATCGTAAAAGAAAAAGAGCTTGTATCTCTGTCCGTATATAACGTAGGCTTCCA
GAGCTGTGATAGCCTGTATCAGTGGGGCCCCGGTATCAGAGACCATTATCTGATTCACTATATCATAAGCGGTAAAGGCC
GCTACACTGTAAATGGCAGTGTTCACACATTAACTCCCGGTGATGCGTTTCTCGTATATCCAAATACCGAAGTGATTTAT
CAGGCTGATGCGCAAGATCCTTGGGAATATACCTGGGTAGGCTTTACCGGCAGCGATGCTGCAACCATTTTAAGAGCCAC
TGATTTCACAAAAGCGCATCCATACATACACAGTGTATCAAACGGAAACGAAATCAAAAGACAGCTCATGCATATATACG
ACGCCAGAGGCACAGAATTTGAAAATGCACTCGAAATGACCGGGCGACTCTACACCACCCTCGCTCTTTTTGTCAGTGCC
GCCACATCAAAGCCGCCGCAAAACAGTGCAAACTCCTATGTACAAAAGGGCATCGAATACATCTCCGCCAACTATTCATA
CCCTATCACCGTTGAGGATATTGCATCATATATAGGCTTAAGCCGAAGTCACCTGTTCCGTTCCTTCCAGAGCATCCTCG
GTGTATCGCCAAAGGAATATCTGACCGATTTCAGAATCAAACAGGCATGCTATCTGCTTAAACACTCCTCATTGTCCATC
ACAGCAATTGCAGGCTCTATAGGGTTTGATAACAGCCTTTATTTTTCAAAGACCTTTCATAAAATAAAAGGCCTTTCGCC
TAAGGAGTATCGCAGTAAATACAAAAAAGCTCAAGAATAA

Upstream 100 bases:

>100_bases
TCCTTTTCATTTTTGTTAAATTTATTGTAGCGCATTTGCTCATTTTTGTATAGAATAAAATGTAGAAGAAATATGTAAAA
ATGTTGTAAAGGTAGGCAAT

Downstream 100 bases:

>100_bases
AAAAAAGCTGCCGGGCTTCACATGAAGCCCGGCAGCTTTTTCATATATCTCTTTATGCTAAACTAAGCAAGCTTAGATTT
AGCAACCTCTACTAATTTAG

Product: transcriptional regulator, AraC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MNNKYKNSYIVKEKELVSLSVYNVGFQSCDSLYQWGPGIRDHYLIHYIISGKGRYTVNGSVHTLTPGDAFLVYPNTEVIY
QADAQDPWEYTWVGFTGSDAATILRATDFTKAHPYIHSVSNGNEIKRQLMHIYDARGTEFENALEMTGRLYTTLALFVSA
ATSKPPQNSANSYVQKGIEYISANYSYPITVEDIASYIGLSRSHLFRSFQSILGVSPKEYLTDFRIKQACYLLKHSSLSI
TAIAGSIGFDNSLYFSKTFHKIKGLSPKEYRSKYKKAQE

Sequences:

>Translated_279_residues
MNNKYKNSYIVKEKELVSLSVYNVGFQSCDSLYQWGPGIRDHYLIHYIISGKGRYTVNGSVHTLTPGDAFLVYPNTEVIY
QADAQDPWEYTWVGFTGSDAATILRATDFTKAHPYIHSVSNGNEIKRQLMHIYDARGTEFENALEMTGRLYTTLALFVSA
ATSKPPQNSANSYVQKGIEYISANYSYPITVEDIASYIGLSRSHLFRSFQSILGVSPKEYLTDFRIKQACYLLKHSSLSI
TAIAGSIGFDNSLYFSKTFHKIKGLSPKEYRSKYKKAQE
>Mature_279_residues
MNNKYKNSYIVKEKELVSLSVYNVGFQSCDSLYQWGPGIRDHYLIHYIISGKGRYTVNGSVHTLTPGDAFLVYPNTEVIY
QADAQDPWEYTWVGFTGSDAATILRATDFTKAHPYIHSVSNGNEIKRQLMHIYDARGTEFENALEMTGRLYTTLALFVSA
ATSKPPQNSANSYVQKGIEYISANYSYPITVEDIASYIGLSRSHLFRSFQSILGVSPKEYLTDFRIKQACYLLKHSSLSI
TAIAGSIGFDNSLYFSKTFHKIKGLSPKEYRSKYKKAQE

Specific function: Regulatory protein for the msm operon for multiple sugar metabolism. Activates the transcription of the msmEFGK, aga, dexB and gftA genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786251, Length=241, Percent_Identity=25.7261410788382, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790559, Length=114, Percent_Identity=34.2105263157895, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI171474011, Length=244, Percent_Identity=23.3606557377049, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 31558; Mature: 31558

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKYKNSYIVKEKELVSLSVYNVGFQSCDSLYQWGPGIRDHYLIHYIISGKGRYTVNGS
CCCCCCCCEEEEHHHEEEEEEECCCHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEECCE
VHTLTPGDAFLVYPNTEVIYQADAQDPWEYTWVGFTGSDAATILRATDFTKAHPYIHSVS
EEEECCCCEEEEECCCEEEEECCCCCCCEEEEEEECCCCHHEEEEECCCCCCCCCEEECC
NGNEIKRQLMHIYDARGTEFENALEMTGRLYTTLALFVSAATSKPPQNSANSYVQKGIEY
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ISANYSYPITVEDIASYIGLSRSHLFRSFQSILGVSPKEYLTDFRIKQACYLLKHSSLSI
HHCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEE
TAIAGSIGFDNSLYFSKTFHKIKGLSPKEYRSKYKKAQE
EEEEECCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNNKYKNSYIVKEKELVSLSVYNVGFQSCDSLYQWGPGIRDHYLIHYIISGKGRYTVNGS
CCCCCCCCEEEEHHHEEEEEEECCCHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEECCE
VHTLTPGDAFLVYPNTEVIYQADAQDPWEYTWVGFTGSDAATILRATDFTKAHPYIHSVS
EEEECCCCEEEEECCCEEEEECCCCCCCEEEEEEECCCCHHEEEEECCCCCCCCCEEECC
NGNEIKRQLMHIYDARGTEFENALEMTGRLYTTLALFVSAATSKPPQNSANSYVQKGIEY
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ISANYSYPITVEDIASYIGLSRSHLFRSFQSILGVSPKEYLTDFRIKQACYLLKHSSLSI
HHCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEE
TAIAGSIGFDNSLYFSKTFHKIKGLSPKEYRSKYKKAQE
EEEEECCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537846; 12397186 [H]