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The map label for this gene is aroC

Identifier: 238924244

GI number: 238924244

Start: 1773559

End: 1774662

Strand: Direct

Name: aroC

Synonym: EUBREC_1882

Alternate gene names: 238924244

Gene position: 1773559-1774662 (Clockwise)

Preceding gene: 238924218

Following gene: 238924261

Centisome position: 51.41

GC content: 44.84

Gene sequence:

>1104_bases
ATGGCAGGTTCATCATACGGAAATATTTTTAAGGTAACAACATGGGGAGAATCACACGGAAAGGGCTTAGGTGTCGTTGT
GGACGGCGTTCCTGCGGGGCTTGAGCTGTGTGAGGAGGATATTCAGATATTCTTAAACAGAAGAAAGCCGGGACAGTCCA
AGTTCACTACTCCACGCAAGGAGGATGATACGGTTGAAATTCTCTCCGGTGTGTTTGAGGGAAAGACTACAGGTACACCT
GTTTCTATGGTTGTGTGGAATAAAAACCAGAAATCAAAGGATTACAGTGAGATTGCTTCATACTATCGTCCGGGACATGC
TGACTTTTGCTTTGATGAGAAATACGGCTTCAGAGACTACAGAGGCGGAGGTCGTTCTTCGGGACGCGAGACAATAGGCC
GTGTTGCAGCAGGTGCTATCGCTGTAAAGATGCTCTCGAGCCTTGGCATAAAATTTCTTACATACACCAGATCAATAGGT
CCTGTTACAATTAATGAGGTTAATTTTGATGCCCATGAGATTTACAACAATTCACTTTATATGCCTGATTCCGATGCAGC
ACAAAAGGCTTCTGAATATCTGGATGAATGCCTTAAATCACTCAATTCCTCAGGCGGTGTGTGTGAATGTGTAATCACAG
GTCTTCCTGTCGGGCTCGGTGATCCTGTATTCGAGAAAATTGATGCCAATCTGGCAAAAGCTATTATGTCTATCGGAGCT
GTAAAGGGCTTCGAAATCGGCGATGGCTTTGATGCAGCAAAGGCAACCGGACTTACAAACAATGATGCCTTTATTATGAT
GGATGGCGCTGTTTCAAAAGAGACAAATCACTCCGGTGGTACTCTCGGCGGCATGACAGACGGCTCACCGCTTATTTTCA
GAGCTGCCATAAAGCCTACTCCTTCAATCGCAGCTACACAGCACACTGTAAATAAATCCGGTGAAGATATAGAGATTTCC
ATCAAGGGACGTCATGACCCGATTATCGTGCCACGTGCTGTTGTTGTTGTTGAAGCTATGGCTGCAATTACTATTGCGGA
TGCACTGCTTATGAATATGGGGGCACGCATGGACCGCATCACAGATTTTTATAAAAAATTATAA

Upstream 100 bases:

>100_bases
CATTGAAAACCAAAAATGCTGTTTACATGCAAGCATGATGTATCATTTTTTGTTCTCAGAGGTTTAAATAGTTACCCATT
ATTATAATAAGGAGACCATC

Downstream 100 bases:

>100_bases
CTTTGTCCTATAGTAAAAAGCATCTATCCGGTTTTCCAGACAGATGCTTTTTATCTATTTCATTGGAACAATCTGTAATG
TTTTTCCTAGTGAATTCAAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MAGSSYGNIFKVTTWGESHGKGLGVVVDGVPAGLELCEEDIQIFLNRRKPGQSKFTTPRKEDDTVEILSGVFEGKTTGTP
VSMVVWNKNQKSKDYSEIASYYRPGHADFCFDEKYGFRDYRGGGRSSGRETIGRVAAGAIAVKMLSSLGIKFLTYTRSIG
PVTINEVNFDAHEIYNNSLYMPDSDAAQKASEYLDECLKSLNSSGGVCECVITGLPVGLGDPVFEKIDANLAKAIMSIGA
VKGFEIGDGFDAAKATGLTNNDAFIMMDGAVSKETNHSGGTLGGMTDGSPLIFRAAIKPTPSIAATQHTVNKSGEDIEIS
IKGRHDPIIVPRAVVVVEAMAAITIADALLMNMGARMDRITDFYKKL

Sequences:

>Translated_367_residues
MAGSSYGNIFKVTTWGESHGKGLGVVVDGVPAGLELCEEDIQIFLNRRKPGQSKFTTPRKEDDTVEILSGVFEGKTTGTP
VSMVVWNKNQKSKDYSEIASYYRPGHADFCFDEKYGFRDYRGGGRSSGRETIGRVAAGAIAVKMLSSLGIKFLTYTRSIG
PVTINEVNFDAHEIYNNSLYMPDSDAAQKASEYLDECLKSLNSSGGVCECVITGLPVGLGDPVFEKIDANLAKAIMSIGA
VKGFEIGDGFDAAKATGLTNNDAFIMMDGAVSKETNHSGGTLGGMTDGSPLIFRAAIKPTPSIAATQHTVNKSGEDIEIS
IKGRHDPIIVPRAVVVVEAMAAITIADALLMNMGARMDRITDFYKKL
>Mature_366_residues
AGSSYGNIFKVTTWGESHGKGLGVVVDGVPAGLELCEEDIQIFLNRRKPGQSKFTTPRKEDDTVEILSGVFEGKTTGTPV
SMVVWNKNQKSKDYSEIASYYRPGHADFCFDEKYGFRDYRGGGRSSGRETIGRVAAGAIAVKMLSSLGIKFLTYTRSIGP
VTINEVNFDAHEIYNNSLYMPDSDAAQKASEYLDECLKSLNSSGGVCECVITGLPVGLGDPVFEKIDANLAKAIMSIGAV
KGFEIGDGFDAAKATGLTNNDAFIMMDGAVSKETNHSGGTLGGMTDGSPLIFRAAIKPTPSIAATQHTVNKSGEDIEISI
KGRHDPIIVPRAVVVVEAMAAITIADALLMNMGARMDRITDFYKKL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=366, Percent_Identity=46.9945355191257, Blast_Score=315, Evalue=4e-87,
Organism=Saccharomyces cerevisiae, GI6321290, Length=371, Percent_Identity=42.8571428571429, Blast_Score=306, Evalue=4e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_EUBR3 (C4ZAX1)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002937760.1
- ProteinModelPortal:   C4ZAX1
- GeneID:   7964077
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_1882
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39323; Mature: 39192

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSSYGNIFKVTTWGESHGKGLGVVVDGVPAGLELCEEDIQIFLNRRKPGQSKFTTPRK
CCCCCCCCEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EDDTVEILSGVFEGKTTGTPVSMVVWNKNQKSKDYSEIASYYRPGHADFCFDEKYGFRDY
CCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCC
RGGGRSSGRETIGRVAAGAIAVKMLSSLGIKFLTYTRSIGPVTINEVNFDAHEIYNNSLY
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCHHHHCCCCEE
MPDSDAAQKASEYLDECLKSLNSSGGVCECVITGLPVGLGDPVFEKIDANLAKAIMSIGA
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
VKGFEIGDGFDAAKATGLTNNDAFIMMDGAVSKETNHSGGTLGGMTDGSPLIFRAAIKPT
CCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCCCCCCCCCEECCCCCCCCEEEEEECCCC
PSIAATQHTVNKSGEDIEISIKGRHDPIIVPRAVVVVEAMAAITIADALLMNMGARMDRI
CCCHHHHHHHCCCCCEEEEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
TDFYKKL
HHHHHCC
>Mature Secondary Structure 
AGSSYGNIFKVTTWGESHGKGLGVVVDGVPAGLELCEEDIQIFLNRRKPGQSKFTTPRK
CCCCCCCEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EDDTVEILSGVFEGKTTGTPVSMVVWNKNQKSKDYSEIASYYRPGHADFCFDEKYGFRDY
CCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCC
RGGGRSSGRETIGRVAAGAIAVKMLSSLGIKFLTYTRSIGPVTINEVNFDAHEIYNNSLY
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCHHHHCCCCEE
MPDSDAAQKASEYLDECLKSLNSSGGVCECVITGLPVGLGDPVFEKIDANLAKAIMSIGA
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
VKGFEIGDGFDAAKATGLTNNDAFIMMDGAVSKETNHSGGTLGGMTDGSPLIFRAAIKPT
CCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCCCCCCCCCEECCCCCCCCEEEEEECCCC
PSIAATQHTVNKSGEDIEISIKGRHDPIIVPRAVVVVEAMAAITIADALLMNMGARMDRI
CCCHHHHHHHCCCCCEEEEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
TDFYKKL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA