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The map label for this gene is gltS [H]

Identifier: 238924214

GI number: 238924214

Start: 1734463

End: 1735650

Strand: Direct

Name: gltS [H]

Synonym: EUBREC_1852

Alternate gene names: 238924214

Gene position: 1734463-1735650 (Clockwise)

Preceding gene: 238924213

Following gene: 238924215

Centisome position: 50.28

GC content: 46.8

Gene sequence:

>1188_bases
ATGAAAATACAACTTGACATGTACCAGACACTGGCCGTTGCAGTGCTTGTACTACTACTTGGAAACTATTTAAAAAAGAA
AATATATTTTCTTCAGAAATTCTGTATTCCGGCGCCTGTCATAGGCGGACTGATTTTTGCCATCATGACATGCATATGCT
ATGTCACAGGAATCGCAGAATTTTCCTTTGACGACACACTGCGCGAGGTCTGCATGGTATTCTTCTTTACATCTGTAGGC
TTTCAGGCAAATCTCAAGGTATTAAAAAGCGGAGGCAAATCGCTCATCGTATTCCTGGGACTGGTAATAGCGCTTATCAT
ATTACAAAACCTAACCGCCGTGGGGCTTGCAAAGCTCTTAAACCTGAATCCGCTAATCGGCATGTGCACCGGCTCTATTC
CTATGGTTGGCGGACACGGCACCGCAGGAGCTTTTGGCCCAGTGCTTGAGGACTTAAACATAAAGGGCGCCACAACCATT
TGTACAGCCGCAGCTACCTTCGGTCTCATCTTTGGAAGCCTGATAGGCGGACCTCTTGGAAAAAGACTGATTGAAAAGCA
TAGCCTGCTTAATACAGCAGCAAACGATGACGACAGCCTGCTGGTGGAGGATGAGAAAAAGCATGAGCGCCACACAAATA
TGTATGCTGATGCCGTATTCCAGCTCATCCTGGCAATAGGTGTCGGAACCATCTTTACAATGCTGCTCACAAAGACAGGG
CTCACCTTCCCAATATATATAGGAGCAATGCTCGCAGCCGCACTAATGCGAAACATATGTGAGTACACAGGAATCGCTAC
CATCCATATGGGAGAGATAAATGACCTAGGAGGTATAAGCCTCTCTCTATTCCTAGGCATGGCAATGATTACACTAAGGC
TCTGGGAGCTTGCATCACTCGCTCTCCCGCTCTTCATACTGCTTGCAGCACAGGTGCTTCTCATAATCATATTCACGTAT
GTTATCGAGTTCAACATCATGGGGCGCGACTACGATGCAGCCATACTTGTGTCAGGCACCTGCGGCTTCGGAACCGGAGC
CACCCCAAATGCCATGGCAAATATGCAGGCTGTCTGCGACCAATATGTGCCATCCATCAAGGCATATCTGCTCATACCGC
TTGTCGGGAGCCTGTTTGCTGACTTTTTGAACAGCCTTGTAATCACATTCTTTATAAACTTACTGTAA

Upstream 100 bases:

>100_bases
ACAAATTAATTCGCGAATTAATTTTTAGTCCAATATATAATATTCAAAATATAAGAAGAAAATAACAAGAATATAATCAA
TAAAAATTGAAAGGTAACAC

Downstream 100 bases:

>100_bases
AACAACCGGAGAAAAATATGTTTGAAAAACTGAAAAAAATATTTAAAAACAGAGACGAAAAAGAAAAACATAATTACGAT
TTAACTTTTGACAACGTGGC

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKIQLDMYQTLAVAVLVLLLGNYLKKKIYFLQKFCIPAPVIGGLIFAIMTCICYVTGIAEFSFDDTLREVCMVFFFTSVG
FQANLKVLKSGGKSLIVFLGLVIALIILQNLTAVGLAKLLNLNPLIGMCTGSIPMVGGHGTAGAFGPVLEDLNIKGATTI
CTAAATFGLIFGSLIGGPLGKRLIEKHSLLNTAANDDDSLLVEDEKKHERHTNMYADAVFQLILAIGVGTIFTMLLTKTG
LTFPIYIGAMLAAALMRNICEYTGIATIHMGEINDLGGISLSLFLGMAMITLRLWELASLALPLFILLAAQVLLIIIFTY
VIEFNIMGRDYDAAILVSGTCGFGTGATPNAMANMQAVCDQYVPSIKAYLLIPLVGSLFADFLNSLVITFFINLL

Sequences:

>Translated_395_residues
MKIQLDMYQTLAVAVLVLLLGNYLKKKIYFLQKFCIPAPVIGGLIFAIMTCICYVTGIAEFSFDDTLREVCMVFFFTSVG
FQANLKVLKSGGKSLIVFLGLVIALIILQNLTAVGLAKLLNLNPLIGMCTGSIPMVGGHGTAGAFGPVLEDLNIKGATTI
CTAAATFGLIFGSLIGGPLGKRLIEKHSLLNTAANDDDSLLVEDEKKHERHTNMYADAVFQLILAIGVGTIFTMLLTKTG
LTFPIYIGAMLAAALMRNICEYTGIATIHMGEINDLGGISLSLFLGMAMITLRLWELASLALPLFILLAAQVLLIIIFTY
VIEFNIMGRDYDAAILVSGTCGFGTGATPNAMANMQAVCDQYVPSIKAYLLIPLVGSLFADFLNSLVITFFINLL
>Mature_395_residues
MKIQLDMYQTLAVAVLVLLLGNYLKKKIYFLQKFCIPAPVIGGLIFAIMTCICYVTGIAEFSFDDTLREVCMVFFFTSVG
FQANLKVLKSGGKSLIVFLGLVIALIILQNLTAVGLAKLLNLNPLIGMCTGSIPMVGGHGTAGAFGPVLEDLNIKGATTI
CTAAATFGLIFGSLIGGPLGKRLIEKHSLLNTAANDDDSLLVEDEKKHERHTNMYADAVFQLILAIGVGTIFTMLLTKTG
LTFPIYIGAMLAAALMRNICEYTGIATIHMGEINDLGGISLSLFLGMAMITLRLWELASLALPLFILLAAQVLLIIIFTY
VIEFNIMGRDYDAAILVSGTCGFGTGATPNAMANMQAVCDQYVPSIKAYLLIPLVGSLFADFLNSLVITFFINLL

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=395, Percent_Identity=38.7341772151899, Blast_Score=234, Evalue=5e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 42455; Mature: 42455

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIQLDMYQTLAVAVLVLLLGNYLKKKIYFLQKFCIPAPVIGGLIFAIMTCICYVTGIAE
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
FSFDDTLREVCMVFFFTSVGFQANLKVLKSGGKSLIVFLGLVIALIILQNLTAVGLAKLL
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLNPLIGMCTGSIPMVGGHGTAGAFGPVLEDLNIKGATTICTAAATFGLIFGSLIGGPLG
CCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
KRLIEKHSLLNTAANDDDSLLVEDEKKHERHTNMYADAVFQLILAIGVGTIFTMLLTKTG
HHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTFPIYIGAMLAAALMRNICEYTGIATIHMGEINDLGGISLSLFLGMAMITLRLWELASL
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALPLFILLAAQVLLIIIFTYVIEFNIMGRDYDAAILVSGTCGFGTGATPNAMANMQAVCD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
QYVPSIKAYLLIPLVGSLFADFLNSLVITFFINLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]