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The map label for this gene is dtd [H]

Identifier: 238924071

GI number: 238924071

Start: 1587394

End: 1587840

Strand: Direct

Name: dtd [H]

Synonym: EUBREC_1709

Alternate gene names: 238924071

Gene position: 1587394-1587840 (Clockwise)

Preceding gene: 238924069

Following gene: 238924072

Centisome position: 46.02

GC content: 40.49

Gene sequence:

>447_bases
ATGAGATTTGTAATACAGCGTGTAAACCATGCAAAGTGCACTATAGATGGAAATATAACCGGCAGCATAGAAAAGGGACT
GTGCGTTTTGATAGGCATAGCAGAGACAGACACTAAAGAGATTGCTGATAAAATGATCAAAAAGCTTATAAACATGAGAA
TTTTTGCCGATGAGAATGACAAGACAAATCTTTCGATAAATGATGTAGACGGAAAGCTTTTGCTCATATCGCAGTTTACG
CTTTATGCAAATTGTAAGAAAGGCAATCGTCCTTCATTTGTGGAGGCAGGAAGTCCTGATATGGCAAACGAGCTTTATGA
ATACTGCATCAGCGAGTGTGATAAGGCAGTTCCAGGAGTACAAAGAGGGGTGTTTGGAGCCGATATGAAGATAGAGCTTG
AGAATGACGGGCCATTTACGATTGTACTGGATTCGGACAAGCTGTAA

Upstream 100 bases:

>100_bases
ATAAAAATGGTAGTAAAACTATATGTCACATAAATTGTAACAAAATAATTATATCCAATTTATAACATGTAAATAACATA
TTTGAGGAGACAACATAATA

Downstream 100 bases:

>100_bases
AAGATATAAGTATGAAAGGCATTTTTATGGAACAATCATTTCTGTTCACAGTTTTTTGGAAAGATGAAATGTACATAGGC
GATATCTCTGAAATGATGGA

Product: D-tyrosyl-tRNA deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MRFVIQRVNHAKCTIDGNITGSIEKGLCVLIGIAETDTKEIADKMIKKLINMRIFADENDKTNLSINDVDGKLLLISQFT
LYANCKKGNRPSFVEAGSPDMANELYEYCISECDKAVPGVQRGVFGADMKIELENDGPFTIVLDSDKL

Sequences:

>Translated_148_residues
MRFVIQRVNHAKCTIDGNITGSIEKGLCVLIGIAETDTKEIADKMIKKLINMRIFADENDKTNLSINDVDGKLLLISQFT
LYANCKKGNRPSFVEAGSPDMANELYEYCISECDKAVPGVQRGVFGADMKIELENDGPFTIVLDSDKL
>Mature_148_residues
MRFVIQRVNHAKCTIDGNITGSIEKGLCVLIGIAETDTKEIADKMIKKLINMRIFADENDKTNLSINDVDGKLLLISQFT
LYANCKKGNRPSFVEAGSPDMANELYEYCISECDKAVPGVQRGVFGADMKIELENDGPFTIVLDSDKL

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=37.1621621621622, Blast_Score=99, Evalue=1e-21,
Organism=Homo sapiens, GI18087837, Length=159, Percent_Identity=27.6729559748428, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI1790320, Length=140, Percent_Identity=41.4285714285714, Blast_Score=129, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=39.1891891891892, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319982, Length=152, Percent_Identity=40.1315789473684, Blast_Score=107, Evalue=6e-25,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=40.1360544217687, Blast_Score=112, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16380; Mature: 16380

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00886 ILVD_EDD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVIQRVNHAKCTIDGNITGSIEKGLCVLIGIAETDTKEIADKMIKKLINMRIFADEND
CCCEEECCCCCEEEECCCEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHCEEEEECCCC
KTNLSINDVDGKLLLISQFTLYANCKKGNRPSFVEAGSPDMANELYEYCISECDKAVPGV
CCEEEEECCCCEEEEEEEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCC
QRGVFGADMKIELENDGPFTIVLDSDKL
CCCCCCCCEEEEECCCCCEEEEEECCCC
>Mature Secondary Structure
MRFVIQRVNHAKCTIDGNITGSIEKGLCVLIGIAETDTKEIADKMIKKLINMRIFADEND
CCCEEECCCCCEEEECCCEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHCEEEEECCCC
KTNLSINDVDGKLLLISQFTLYANCKKGNRPSFVEAGSPDMANELYEYCISECDKAVPGV
CCEEEEECCCCEEEEEEEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCC
QRGVFGADMKIELENDGPFTIVLDSDKL
CCCCCCCCEEEEECCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA