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The map label for this gene is recU [H]

Identifier: 238924046

GI number: 238924046

Start: 1567246

End: 1567860

Strand: Direct

Name: recU [H]

Synonym: EUBREC_1684

Alternate gene names: 238924046

Gene position: 1567246-1567860 (Clockwise)

Preceding gene: 238924045

Following gene: 238924047

Centisome position: 45.43

GC content: 44.23

Gene sequence:

>615_bases
ATGGAGCAGGGTGGGGCTTTAAACCCGTCATTATTTACTTTACATCGCATAGCTTACAGTATTAAGGAAGATAGAAACGA
TATGGCAACCTGGAATTCAAGAGGCTTAAGAGGCTCGACCTTAGAGGACATGATAAACAAGACAAATGAAAAATACAGGG
AGAACGGCCTGGCGCTCATACAAAAGATTCCCACTCCGATTACACCTATAAAGATGGAGCCGGAAACCAGACACATTACA
CTGGCTTATTTCGAGCAGAAGAGTACGGTTGACTATATTGGCGCTGTACAGGGAATCCCGGTATGCTTTGATGCAAAGGA
ATGTAATACCGACACGTTTCCCCTTGCCAATATACATGAGCATCAGGTAGAGTTTATGAGATGCTTTGAAAAACAGGATG
GTGTTGCATTTATCCTTATATCGTACACACACAGGAACGAATACTATTATCTCACATTTAAAAAACTGACAGAATTCTGG
GATAGAGCTGCAGAAGGCGGCAGAAAGAGCTTCCGCTATGAGGAGCTTGAGCCGGCATTTTTCCTCCCGGAGGTGCCCGG
AATACTTGTGCCGTATCTGAACGCTCTTCAGCTTGACTTAAATTGCAGGGCTTGA

Upstream 100 bases:

>100_bases
CTTTTTACAAAGAAAATTATCATGTGACCAGCCAGCTTTTGCATGCGCACCATGTGATTTTGCCTGATGGCAGATATATA
GAGGCGGCTTTGCCTGACAT

Downstream 100 bases:

>100_bases
CAGTATTACTATCGTATGGTAGCATATTACCACGATAACACTTTACTACAAGAAAGCGAGATTTTACAGATTATGGAAAA
TCAATTATTACACACTCCGG

Product: Holliday junction-specific endonuclease

Products: NA

Alternate protein names: Recombination protein U homolog [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MEQGGALNPSLFTLHRIAYSIKEDRNDMATWNSRGLRGSTLEDMINKTNEKYRENGLALIQKIPTPITPIKMEPETRHIT
LAYFEQKSTVDYIGAVQGIPVCFDAKECNTDTFPLANIHEHQVEFMRCFEKQDGVAFILISYTHRNEYYYLTFKKLTEFW
DRAAEGGRKSFRYEELEPAFFLPEVPGILVPYLNALQLDLNCRA

Sequences:

>Translated_204_residues
MEQGGALNPSLFTLHRIAYSIKEDRNDMATWNSRGLRGSTLEDMINKTNEKYRENGLALIQKIPTPITPIKMEPETRHIT
LAYFEQKSTVDYIGAVQGIPVCFDAKECNTDTFPLANIHEHQVEFMRCFEKQDGVAFILISYTHRNEYYYLTFKKLTEFW
DRAAEGGRKSFRYEELEPAFFLPEVPGILVPYLNALQLDLNCRA
>Mature_204_residues
MEQGGALNPSLFTLHRIAYSIKEDRNDMATWNSRGLRGSTLEDMINKTNEKYRENGLALIQKIPTPITPIKMEPETRHIT
LAYFEQKSTVDYIGAVQGIPVCFDAKECNTDTFPLANIHEHQVEFMRCFEKQDGVAFILISYTHRNEYYYLTFKKLTEFW
DRAAEGGRKSFRYEELEPAFFLPEVPGILVPYLNALQLDLNCRA

Specific function: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair

COG id: COG3331

COG function: function code R; Penicillin-binding protein-related factor A, putative recombinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recU family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004612
- InterPro:   IPR011335 [H]

Pfam domain/function: PF03838 RecU [H]

EC number: NA

Molecular weight: Translated: 23612; Mature: 23612

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQGGALNPSLFTLHRIAYSIKEDRNDMATWNSRGLRGSTLEDMINKTNEKYRENGLALI
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QKIPTPITPIKMEPETRHITLAYFEQKSTVDYIGAVQGIPVCFDAKECNTDTFPLANIHE
HHCCCCCCCEEECCCCCEEEEEEECCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCHH
HQVEFMRCFEKQDGVAFILISYTHRNEYYYLTFKKLTEFWDRAAEGGRKSFRYEELEPAF
HHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCE
FLPEVPGILVPYLNALQLDLNCRA
ECCCCCCHHHHCCCCEEEEEECCC
>Mature Secondary Structure
MEQGGALNPSLFTLHRIAYSIKEDRNDMATWNSRGLRGSTLEDMINKTNEKYRENGLALI
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QKIPTPITPIKMEPETRHITLAYFEQKSTVDYIGAVQGIPVCFDAKECNTDTFPLANIHE
HHCCCCCCCEEECCCCCEEEEEEECCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCHH
HQVEFMRCFEKQDGVAFILISYTHRNEYYYLTFKKLTEFWDRAAEGGRKSFRYEELEPAF
HHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCE
FLPEVPGILVPYLNALQLDLNCRA
ECCCCCCHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA