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The map label for this gene is ruvB [H]

Identifier: 238924019

GI number: 238924019

Start: 1541821

End: 1542588

Strand: Direct

Name: ruvB [H]

Synonym: EUBREC_1657

Alternate gene names: 238924019

Gene position: 1541821-1542588 (Clockwise)

Preceding gene: 238924018

Following gene: 238924020

Centisome position: 44.69

GC content: 47.53

Gene sequence:

>768_bases
ATGGGCACAAAGATAAAGGTGACCTCCGGTCCTGCAATAGGTAAGCCGGGAGAGATGGCAGCCATACTCAACGGACTTTC
TGAGGGAGATATACTGTTTGTCGATGAGATTCACAGATTAAACCGTCAGGTGGAGGAGGTGCTCTATCCTGCCATGGAGG
ATTACGCCATTGATATCATGATTGGTAAGGGTGAGTCTGCAAAGTCAATCAGATTCAACCTGCCAAAATTCACCCTTGTA
GGTGCAACAACGAGGGCGGGTATGCTTTCGGCACCTTTACGCGACAGGTTTGGTGTGGTAAATCACATGGAGTTTTACAC
TGTCGATGAGCTAAAGCATATTATCGTCAATTCCGCAAAGGTGCTTGGAGTTGAGATAGATGACAAGGGAGCCTACGAGA
TGGCGCGTCGTTCAAGAGGTACCCCAAGACTTGCAAACAGACTTCTAAAGCGTGTCAGGGATTTTGCGCAGGTCAAGTAT
GACGGCAAAATCACCTATGATGTGGCAAGCTTTGCACTGGATCTTTTGGAAGTGGACAAGTACGGACTGGATTTAAACGA
TAGAAATATACTTCTCACCATCATTGACAAGTTTGCGGGAGGACCGGTAGGTCTTGATACGCTTGCAGCGGCAATAGGTG
AGGATGCCGGAACCATTGAGGATGTTTACGAGCCGTATCTGGTGAAGAACGGCTTCATAAACCGCACACCAAAGGGACGT
GTGGCAACAGAACTAGCCTTTGAGCATTTTGAGAGAAAAAGGGCTTAA

Upstream 100 bases:

>100_bases
TTGAAGCCGCAAAATCAAGGGGCGAGGCGCTCGATCATGTGCTGTTTTATGGCCCCCGGGACTTGGAAAGACAACACTTG
CAGGAATCATTGCAAATGAG

Downstream 100 bases:

>100_bases
AGTTGCAATTTATATCTATAAGGCATATAATAATTAAGTATTTGATATTGAAATTGATATTAATAGTAATATTAATACTA
ATATAGCTGGTTTGAATAAA

Product: Holliday junction DNA helicase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MGTKIKVTSGPAIGKPGEMAAILNGLSEGDILFVDEIHRLNRQVEEVLYPAMEDYAIDIMIGKGESAKSIRFNLPKFTLV
GATTRAGMLSAPLRDRFGVVNHMEFYTVDELKHIIVNSAKVLGVEIDDKGAYEMARRSRGTPRLANRLLKRVRDFAQVKY
DGKITYDVASFALDLLEVDKYGLDLNDRNILLTIIDKFAGGPVGLDTLAAAIGEDAGTIEDVYEPYLVKNGFINRTPKGR
VATELAFEHFERKRA

Sequences:

>Translated_255_residues
MGTKIKVTSGPAIGKPGEMAAILNGLSEGDILFVDEIHRLNRQVEEVLYPAMEDYAIDIMIGKGESAKSIRFNLPKFTLV
GATTRAGMLSAPLRDRFGVVNHMEFYTVDELKHIIVNSAKVLGVEIDDKGAYEMARRSRGTPRLANRLLKRVRDFAQVKY
DGKITYDVASFALDLLEVDKYGLDLNDRNILLTIIDKFAGGPVGLDTLAAAIGEDAGTIEDVYEPYLVKNGFINRTPKGR
VATELAFEHFERKRA
>Mature_254_residues
GTKIKVTSGPAIGKPGEMAAILNGLSEGDILFVDEIHRLNRQVEEVLYPAMEDYAIDIMIGKGESAKSIRFNLPKFTLVG
ATTRAGMLSAPLRDRFGVVNHMEFYTVDELKHIIVNSAKVLGVEIDDKGAYEMARRSRGTPRLANRLLKRVRDFAQVKYD
GKITYDVASFALDLLEVDKYGLDLNDRNILLTIIDKFAGGPVGLDTLAAAIGEDAGTIEDVYEPYLVKNGFINRTPKGRV
ATELAFEHFERKRA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=250, Percent_Identity=61.6, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 28237; Mature: 28106

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTKIKVTSGPAIGKPGEMAAILNGLSEGDILFVDEIHRLNRQVEEVLYPAMEDYAIDIM
CCCEEEEECCCCCCCCCHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEE
IGKGESAKSIRFNLPKFTLVGATTRAGMLSAPLRDRFGVVNHMEFYTVDELKHIIVNSAK
EECCCCCCEEEEECCEEEEEECCCCCCHHCCCHHHHCCCHHCHHEEEHHHHHHHHHCCCE
VLGVEIDDKGAYEMARRSRGTPRLANRLLKRVRDFAQVKYDGKITYDVASFALDLLEVDK
EEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHEEECCEEEHHHHHHHHHHHHHHH
YGLDLNDRNILLTIIDKFAGGPVGLDTLAAAIGEDAGTIEDVYEPYLVKNGFINRTPKGR
HCCCCCCCCEEEEEEHHHCCCCCCHHHHHHHHCCCCCCHHHHHCCHHHCCCCCCCCCCCH
VATELAFEHFERKRA
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
GTKIKVTSGPAIGKPGEMAAILNGLSEGDILFVDEIHRLNRQVEEVLYPAMEDYAIDIM
CCEEEEECCCCCCCCCHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEE
IGKGESAKSIRFNLPKFTLVGATTRAGMLSAPLRDRFGVVNHMEFYTVDELKHIIVNSAK
EECCCCCCEEEEECCEEEEEECCCCCCHHCCCHHHHCCCHHCHHEEEHHHHHHHHHCCCE
VLGVEIDDKGAYEMARRSRGTPRLANRLLKRVRDFAQVKYDGKITYDVASFALDLLEVDK
EEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHEEECCEEEHHHHHHHHHHHHHHH
YGLDLNDRNILLTIIDKFAGGPVGLDTLAAAIGEDAGTIEDVYEPYLVKNGFINRTPKGR
HCCCCCCCCEEEEEEHHHCCCCCCHHHHHHHHCCCCCCHHHHHCCHHHCCCCCCCCCCCH
VATELAFEHFERKRA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA