Click here to switch to the map view.

The map label for this gene is yqjD [H]

Identifier: 238923988

GI number: 238923988

Start: 1516272

End: 1517708

Strand: Direct

Name: yqjD [H]

Synonym: EUBREC_1626

Alternate gene names: 238923988

Gene position: 1516272-1517708 (Clockwise)

Preceding gene: 238923987

Following gene: 238923989

Centisome position: 43.95

GC content: 42.87

Gene sequence:

>1437_bases
ATGAGTAGTAACAATCAAAGCTTGGCAATGCAGCGTATTGCTAAGTTAGTCGACGAGAACAGTTTCATGGAAATTGGTTC
TCTTGTGACAGCTCGCAGTACAGATTTTAACCTTACTGCAGCAAAAGCTCCTTCAGATGGTGTTATTATCGGACACGGTC
TGATTGATGGAAATCTTGTATTTATCTACAGCCAGGATGCAACAGTTCTTAACGGAACAATCGGCGAGATGCATGCAAAG
AAAATTGCTTCTGTATATGATATGGCCATGAAAATGGGCGCACCTGTTATCGGATTTATCGATTGCGGTGGTATCAGACT
TCAGGAGTCAGTTGATGCATTAGACGGATTTGGTCTTATCTACGCCAAGGAAGTTGCAGCAAGTGGCGTTATTCCACAGA
TTTGTGGTGTATTCGGTAATTGTGGTGGCGGACTTTCTGTAGTACCGGCTCTTTGTGATTTCGCTTATATCGAAGAGTCT
AAGGGCAGAATGTTTATTAATACTCCTGATGCAATAGAGGGTAACCGCGTTGAGAAATGCGATACAGCAGCAGCTTCATT
CCAGAGTGAGAACAACGGATGTGTAGACGGAATCGGTTCAGAGGATGATATTATCGCTGATATCAGAGCTCTTGTCAGCA
TGCTTCCACTCAACAACGAGGGAGATGTATATACAGACTCATGTGAGGATGATCTCAACAGAGCATGTAACAGCATGGCT
GATATGAAGGCTGATCCAAGATTCCTCTTATCAGAGCTTTCTGATGATCATGTATTCTTTGAGACAAAGAAAGACTTTGC
CAAGAATATGGTAACAGGCTTTGTTAAATTAAACGGCATGACAGTCGGTGCAGTTGCAAACTGCAGCACAGTATATGATG
CTGAGGGCAAGAAGGCAGAGGAGTTTGCACTTTCTCTTACTGCAAAGGGCTGTAACAAGGCAGCTGAGTTTGTATCATTC
TGTGATGCTTTCTCAATTCCTGTACTTACACTTACAAATGTAAACGGATTCAAGAACTGCATGTGCTCTGAGAAGAAGCT
TGCAAAGGCTCTTGCCAGAATGACATACGCATTCTCTAGTGCAACATGTCCAAAGGTTAACCTGATTACAGGCGAGGCTT
ACGGAAGCGCATATGTTGCAATGAACTCTAAGTCAATCGGAGCTGATATGGTTTATGCATACCCTGATGCAAAGATTGGT
ATGATGGATTCAAAGATTGCAGCTGAGATTATGTATCCGGGCGCTGATGCAAAGGAAATCGATGAGAAGGCAGCTGATTA
CGAGAAGCTTCAGTCTTCTGTTTCATCAGCAGCAGCCAGAGGATATGTAGACCTCATCATTGATCCGGCTGACACAAGAA
AATATCTTGTAGGTGCTTTTGAGATGCTTTACACCAAATATGTAGATGCACCAGAGAAGAAACACGGAACTAAATAA

Upstream 100 bases:

>100_bases
TTAAAGTTAAAAATTTAACAAATTAGTTGAAAAAAATTTAGAAATAGTCTATTATCATACTAGCGAAAAATTTTATTTTT
TTATAGATGGAGGATATAAA

Downstream 100 bases:

>100_bases
TAGAAAGGCGCATTTTGTTATGAAGAAAAAAATAACATATATCCTTAGCCTTCTTATGATTGTATGTATGCTTGGAGCAT
GTGGCTCTGACAATGCCGAA

Product: propionyl-CoA carboxylase

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MSSNNQSLAMQRIAKLVDENSFMEIGSLVTARSTDFNLTAAKAPSDGVIIGHGLIDGNLVFIYSQDATVLNGTIGEMHAK
KIASVYDMAMKMGAPVIGFIDCGGIRLQESVDALDGFGLIYAKEVAASGVIPQICGVFGNCGGGLSVVPALCDFAYIEES
KGRMFINTPDAIEGNRVEKCDTAAASFQSENNGCVDGIGSEDDIIADIRALVSMLPLNNEGDVYTDSCEDDLNRACNSMA
DMKADPRFLLSELSDDHVFFETKKDFAKNMVTGFVKLNGMTVGAVANCSTVYDAEGKKAEEFALSLTAKGCNKAAEFVSF
CDAFSIPVLTLTNVNGFKNCMCSEKKLAKALARMTYAFSSATCPKVNLITGEAYGSAYVAMNSKSIGADMVYAYPDAKIG
MMDSKIAAEIMYPGADAKEIDEKAADYEKLQSSVSSAAARGYVDLIIDPADTRKYLVGAFEMLYTKYVDAPEKKHGTK

Sequences:

>Translated_478_residues
MSSNNQSLAMQRIAKLVDENSFMEIGSLVTARSTDFNLTAAKAPSDGVIIGHGLIDGNLVFIYSQDATVLNGTIGEMHAK
KIASVYDMAMKMGAPVIGFIDCGGIRLQESVDALDGFGLIYAKEVAASGVIPQICGVFGNCGGGLSVVPALCDFAYIEES
KGRMFINTPDAIEGNRVEKCDTAAASFQSENNGCVDGIGSEDDIIADIRALVSMLPLNNEGDVYTDSCEDDLNRACNSMA
DMKADPRFLLSELSDDHVFFETKKDFAKNMVTGFVKLNGMTVGAVANCSTVYDAEGKKAEEFALSLTAKGCNKAAEFVSF
CDAFSIPVLTLTNVNGFKNCMCSEKKLAKALARMTYAFSSATCPKVNLITGEAYGSAYVAMNSKSIGADMVYAYPDAKIG
MMDSKIAAEIMYPGADAKEIDEKAADYEKLQSSVSSAAARGYVDLIIDPADTRKYLVGAFEMLYTKYVDAPEKKHGTK
>Mature_477_residues
SSNNQSLAMQRIAKLVDENSFMEIGSLVTARSTDFNLTAAKAPSDGVIIGHGLIDGNLVFIYSQDATVLNGTIGEMHAKK
IASVYDMAMKMGAPVIGFIDCGGIRLQESVDALDGFGLIYAKEVAASGVIPQICGVFGNCGGGLSVVPALCDFAYIEESK
GRMFINTPDAIEGNRVEKCDTAAASFQSENNGCVDGIGSEDDIIADIRALVSMLPLNNEGDVYTDSCEDDLNRACNSMAD
MKADPRFLLSELSDDHVFFETKKDFAKNMVTGFVKLNGMTVGAVANCSTVYDAEGKKAEEFALSLTAKGCNKAAEFVSFC
DAFSIPVLTLTNVNGFKNCMCSEKKLAKALARMTYAFSSATCPKVNLITGEAYGSAYVAMNSKSIGADMVYAYPDAKIGM
MDSKIAAEIMYPGADAKEIDEKAADYEKLQSSVSSAAARGYVDLIIDPADTRKYLVGAFEMLYTKYVDAPEKKHGTK

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=481, Percent_Identity=35.5509355509356, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI295821216, Length=501, Percent_Identity=34.1317365269461, Blast_Score=275, Evalue=9e-74,
Organism=Homo sapiens, GI11545863, Length=484, Percent_Identity=27.2727272727273, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI25147359, Length=481, Percent_Identity=36.7983367983368, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI25147362, Length=481, Percent_Identity=36.7983367983368, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI17552936, Length=508, Percent_Identity=27.1653543307087, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24586065, Length=506, Percent_Identity=27.2727272727273, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 51072; Mature: 50940

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNNQSLAMQRIAKLVDENSFMEIGSLVTARSTDFNLTAAKAPSDGVIIGHGLIDGNLV
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCEEEEECCCCCCEEEEEEEECCCEE
FIYSQDATVLNGTIGEMHAKKIASVYDMAMKMGAPVIGFIDCGGIRLQESVDALDGFGLI
EEEECCCEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEHHHHHHHCCCCCE
YAKEVAASGVIPQICGVFGNCGGGLSVVPALCDFAYIEESKGRMFINTPDAIEGNRVEKC
EHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHH
DTAAASFQSENNGCVDGIGSEDDIIADIRALVSMLPLNNEGDVYTDSCEDDLNRACNSMA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHH
DMKADPRFLLSELSDDHVFFETKKDFAKNMVTGFVKLNGMTVGAVANCSTVYDAEGKKAE
HCCCCHHHHHHHCCCCCEEEECHHHHHHHHHEEEEEECCEEEECCCCCCEEECCCCCCHH
EFALSLTAKGCNKAAEFVSFCDAFSIPVLTLTNVNGFKNCMCSEKKLAKALARMTYAFSS
HHEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHCC
ATCPKVNLITGEAYGSAYVAMNSKSIGADMVYAYPDAKIGMMDSKIAAEIMYPGADAKEI
CCCCEEEEEECCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCHHHHHEEECCCCCHHHH
DEKAADYEKLQSSVSSAAARGYVDLIIDPADTRKYLVGAFEMLYTKYVDAPEKKHGTK
HHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SSNNQSLAMQRIAKLVDENSFMEIGSLVTARSTDFNLTAAKAPSDGVIIGHGLIDGNLV
CCCCHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCEEEEECCCCCCEEEEEEEECCCEE
FIYSQDATVLNGTIGEMHAKKIASVYDMAMKMGAPVIGFIDCGGIRLQESVDALDGFGLI
EEEECCCEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEHHHHHHHCCCCCE
YAKEVAASGVIPQICGVFGNCGGGLSVVPALCDFAYIEESKGRMFINTPDAIEGNRVEKC
EHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHH
DTAAASFQSENNGCVDGIGSEDDIIADIRALVSMLPLNNEGDVYTDSCEDDLNRACNSMA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHH
DMKADPRFLLSELSDDHVFFETKKDFAKNMVTGFVKLNGMTVGAVANCSTVYDAEGKKAE
HCCCCHHHHHHHCCCCCEEEECHHHHHHHHHEEEEEECCEEEECCCCCCEEECCCCCCHH
EFALSLTAKGCNKAAEFVSFCDAFSIPVLTLTNVNGFKNCMCSEKKLAKALARMTYAFSS
HHEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHCC
ATCPKVNLITGEAYGSAYVAMNSKSIGADMVYAYPDAKIGMMDSKIAAEIMYPGADAKEI
CCCCEEEEEECCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCHHHHHEEECCCCCHHHH
DEKAADYEKLQSSVSSAAARGYVDLIIDPADTRKYLVGAFEMLYTKYVDAPEKKHGTK
HHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]