Click here to switch to the map view.

The map label for this gene is argC [H]

Identifier: 238923970

GI number: 238923970

Start: 1496837

End: 1497961

Strand: Direct

Name: argC [H]

Synonym: EUBREC_1608

Alternate gene names: 238923970

Gene position: 1496837-1497961 (Clockwise)

Preceding gene: 238923968

Following gene: 238923971

Centisome position: 43.39

GC content: 43.64

Gene sequence:

>1125_bases
ATGTATGATGCGTCAGACCCATTTTATATGGTTATGCAGAAATACAATATGAAAAGAGGAAATACTATGATAAAGGCTGG
TATTATTGGAGCCACCGGATATGCCGGAGCAGAGCTCGTGAGAATTTTGATGAATCATAAAGAGGTAGAGATTGCATGGT
ATGGCTCACGAAGCTATGTGGATGAGAATTATGCCGATATCTATGGAAATATGTTTCAGATAGTTGATGCAAAGTGCATG
GATGACAATATGGAGGAGCTTGCAGAGTCTGTTGATGTGATTTTCACTGCGACCCCACAGGGCTTTTTGGCAGGCGTGCT
CACTGAGGATATATTAAGTAAGGTAAAGATTGTCGATCTGTCAGCGGACTTCCGTATCAAGGATGTAGCCACATATGAGA
AATGGTACAAGATTGAGCACAAGTCGCCGCAGTTTATTGATGAGGCTGTATATGGTCTGTGTGAGATAAACAGGGACAAG
GTCACAAAGGAGACAAGGCTTGTTGCAAATCCTGGCTGCTATACCACATGCTCCATCCTTACAGCTTATCCGCTTGTGAA
GGAGGGACTTATTGACACAGATACACTTATCGTCGATGCAAAGTCAGGCACATCAGGCGCAGGACGTGGTGCAAAGACAC
CTAATCTGTTTTGTGAAGTAAATGAGAGCATGAAGGCATATGGCGTTGCCTCACACAGACATACCCCTGAGATAGAGGAA
CAGCTTGGATATGCGGCAGGAAAAGAAATTCTTATCAACTTTACTCCGCATCTTGTTCCGATGAACAGAGGAATCCTCGC
TACAGAGTATGCGACACTTAAGAAAAAACCTGATGGAACACTTCCTACATATGATGAGATTAAGGCAGTTTACGATAAGT
ATTATGCAAATGAGAAGTTTGTCAGAGTGCTCAAAAAGGGTGTCTGCCCTGAGACAAAGTGGGTTGAGGGCAGCAACTAT
GTGGATGTAAACTTTGTGATTGATGAGAGGACCGGCAGAATTATTATGATGGGTGCTCTTGACAATCTGGTAAAGGGTGC
TGCAGGACAGGCGGTTCAGAATATGAATCTGTTATTTGGCTTCGATGAGGCAGAGGGACTCAATATGGTTCCTATGTTCC
CGTAA

Upstream 100 bases:

>100_bases
ACATATTGCAAGTGAAAAAATATACATTATTCATGTATAATTATACATAATTTTGTATAATTTTTCTCTTTACGGATTGA
AATTACTGTACTATATTATT

Downstream 100 bases:

>100_bases
TAATTAATAATAGGAAAGTAATTATCAGAAAGATGCATTATAATGCTGATAGTTATATAAAAATATAAGGATGATTTAAT
AAAATGAGTAATGAGAATAA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MYDASDPFYMVMQKYNMKRGNTMIKAGIIGATGYAGAELVRILMNHKEVEIAWYGSRSYVDENYADIYGNMFQIVDAKCM
DDNMEELAESVDVIFTATPQGFLAGVLTEDILSKVKIVDLSADFRIKDVATYEKWYKIEHKSPQFIDEAVYGLCEINRDK
VTKETRLVANPGCYTTCSILTAYPLVKEGLIDTDTLIVDAKSGTSGAGRGAKTPNLFCEVNESMKAYGVASHRHTPEIEE
QLGYAAGKEILINFTPHLVPMNRGILATEYATLKKKPDGTLPTYDEIKAVYDKYYANEKFVRVLKKGVCPETKWVEGSNY
VDVNFVIDERTGRIIMMGALDNLVKGAAGQAVQNMNLLFGFDEAEGLNMVPMFP

Sequences:

>Translated_374_residues
MYDASDPFYMVMQKYNMKRGNTMIKAGIIGATGYAGAELVRILMNHKEVEIAWYGSRSYVDENYADIYGNMFQIVDAKCM
DDNMEELAESVDVIFTATPQGFLAGVLTEDILSKVKIVDLSADFRIKDVATYEKWYKIEHKSPQFIDEAVYGLCEINRDK
VTKETRLVANPGCYTTCSILTAYPLVKEGLIDTDTLIVDAKSGTSGAGRGAKTPNLFCEVNESMKAYGVASHRHTPEIEE
QLGYAAGKEILINFTPHLVPMNRGILATEYATLKKKPDGTLPTYDEIKAVYDKYYANEKFVRVLKKGVCPETKWVEGSNY
VDVNFVIDERTGRIIMMGALDNLVKGAAGQAVQNMNLLFGFDEAEGLNMVPMFP
>Mature_374_residues
MYDASDPFYMVMQKYNMKRGNTMIKAGIIGATGYAGAELVRILMNHKEVEIAWYGSRSYVDENYADIYGNMFQIVDAKCM
DDNMEELAESVDVIFTATPQGFLAGVLTEDILSKVKIVDLSADFRIKDVATYEKWYKIEHKSPQFIDEAVYGLCEINRDK
VTKETRLVANPGCYTTCSILTAYPLVKEGLIDTDTLIVDAKSGTSGAGRGAKTPNLFCEVNESMKAYGVASHRHTPEIEE
QLGYAAGKEILINFTPHLVPMNRGILATEYATLKKKPDGTLPTYDEIKAVYDKYYANEKFVRVLKKGVCPETKWVEGSNY
VDVNFVIDERTGRIIMMGALDNLVKGAAGQAVQNMNLLFGFDEAEGLNMVPMFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=350, Percent_Identity=36.2857142857143, Blast_Score=194, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6320913, Length=356, Percent_Identity=30.8988764044944, Blast_Score=126, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 41717; Mature: 41717

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDASDPFYMVMQKYNMKRGNTMIKAGIIGATGYAGAELVRILMNHKEVEIAWYGSRSYV
CCCCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCC
DENYADIYGNMFQIVDAKCMDDNMEELAESVDVIFTATPQGFLAGVLTEDILSKVKIVDL
CCCHHHHHCCHHHHHHHHHCCCCHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHEEEEEE
SADFRIKDVATYEKWYKIEHKSPQFIDEAVYGLCEINRDKVTKETRLVANPGCYTTCSIL
CCCCEEEHHHHHHHHEEECCCCCHHHHHHHHHHHHCCHHHCCHHHEEEECCCCHHHHHHH
TAYPLVKEGLIDTDTLIVDAKSGTSGAGRGAKTPNLFCEVNESMKAYGVASHRHTPEIEE
HHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCHHH
QLGYAAGKEILINFTPHLVPMNRGILATEYATLKKKPDGTLPTYDEIKAVYDKYYANEKF
HHCHHCCCEEEEEECCCEEECCCCEEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHH
VRVLKKGVCPETKWVEGSNYVDVNFVIDERTGRIIMMGALDNLVKGAAGQAVQNMNLLFG
HHHHHHCCCCCCEEECCCCEEEEEEEEECCCCCEEEEECHHHHHHCCCCHHHHCCEEEEE
FDEAEGLNMVPMFP
CCCCCCCCCCCCCC
>Mature Secondary Structure
MYDASDPFYMVMQKYNMKRGNTMIKAGIIGATGYAGAELVRILMNHKEVEIAWYGSRSYV
CCCCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCC
DENYADIYGNMFQIVDAKCMDDNMEELAESVDVIFTATPQGFLAGVLTEDILSKVKIVDL
CCCHHHHHCCHHHHHHHHHCCCCHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHEEEEEE
SADFRIKDVATYEKWYKIEHKSPQFIDEAVYGLCEINRDKVTKETRLVANPGCYTTCSIL
CCCCEEEHHHHHHHHEEECCCCCHHHHHHHHHHHHCCHHHCCHHHEEEECCCCHHHHHHH
TAYPLVKEGLIDTDTLIVDAKSGTSGAGRGAKTPNLFCEVNESMKAYGVASHRHTPEIEE
HHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCHHH
QLGYAAGKEILINFTPHLVPMNRGILATEYATLKKKPDGTLPTYDEIKAVYDKYYANEKF
HHCHHCCCEEEEEECCCEEECCCCEEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHH
VRVLKKGVCPETKWVEGSNYVDVNFVIDERTGRIIMMGALDNLVKGAAGQAVQNMNLLFG
HHHHHHCCCCCCEEECCCCEEEEEEEEECCCCCEEEEECHHHHHHCCCCHHHHCCEEEEE
FDEAEGLNMVPMFP
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA