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The map label for this gene is glnS [H]

Identifier: 238923965

GI number: 238923965

Start: 1490866

End: 1492551

Strand: Direct

Name: glnS [H]

Synonym: EUBREC_1603

Alternate gene names: 238923965

Gene position: 1490866-1492551 (Clockwise)

Preceding gene: 238923964

Following gene: 238923966

Centisome position: 43.22

GC content: 44.07

Gene sequence:

>1686_bases
ATGGAGAACGAGGCAACAGTTTCGAAAAATTTTATTGAACAGATTATTGAGAAGGACTTGGCTGAGGGTCATTGCAAGAC
TGTAAAGACCAGATTCCCACCGGAGCCAAACGGTTATTTGCATATCGGCCATGCGAAGTCTATTCTTTTAAACTATGGAC
TGGCAAAGAAGTATGACGGACAGTTCAATCTCAGGTTTGATGATACAAACCCTACCAAGGAGCGTCTGGAGTTTGTAGAG
TCTATCGAGGCCGATGTTAAGTGGCTTGGTGCTGACTGGGCTGACAGGAAGTTTTTTGCATCCAATTACTTCGACAAGAT
GTATGAGTGTGCAGTAGGACTGATAAAGAAGGGAAAGGCATATGTATCTGATCTGACACCTGATGAGATAAGAGAGTATA
GAGGTACACTCACAGAGGCCGGCAAGGAGGATCCATACTCAAAGAGAAGTGTTGAGGAAAACTTAGACCTTTTTGAGCGC
ATGAAAAACGGTGAGTTCGAGGATGGCACAAAGGTACTTCGTGCGAGAATTGACATGAGCTCTTCAAACATCAATATGAG
AGATCCGATTCTTTACCGTGTGGCTCATATGACACATCACAATACAGGTGATAAATGGTGTGTATATCCTATGTATGATT
TTGCTCATCCTATAGAGGATGCTATTGAGGGCATCACACATTCTATATGTACTCTTGAGTTTGAAGACCACAGACCGCTG
TATGATTGGGTGGTTATTGAATGTGGATTTAAGAATTCTCCAGAGGAGTCGCCAAAGCAGATTGAGTTTGCAAAGCTCTA
TCTGACTAATGTTGTAACAGGAAAGAGATATATCAAGCGTCTTGTTGAGGACGGTATCGTTGATGGCTGGGATGACCCGA
GGCTTGTTTCTATAGCAGCGCTCAGACGCAGGGGCTTCACACCGGAGTCTATCCAGAATTTTGTTGATCTGTGTGGTATA
TCAAAAGCTAACAGCTCTGTTGACTACGCTATGCTTGAGTACTGTATCCGAGAGGATTTAAAGGCTAAGCGCCCTCGTAT
GATGGCTGTGCTTGATCCGGTCAAGGTGATTATCGACAATTACCCTGAGGGACAGGTTGAGTATCTTGAAGTGGACAATA
ACGTGGAGAATCCTGAGCTTGGAAAGAGAAAAGTTCCTTTCACCAGAGAGCTTTATGTGGAGAGAGATGACTTCATGGAG
GAGCCACCGAAGAAGTATTTCCGTATGTTCCCTGGCAATGAGGTGCGTTTCATGAATGCTTATTTTGTGAAGTGCAATAG
CTGTGTGAAGGACGAAAACGGCAATATTACAGAGATTCACTGTACATATGATCCGGCATCAAAGGGTGGCAACAGTCCTG
ATGGCAGAAAGGTCAAGGGAACTATCCACTGGGTTTCAGCCGAGTATGGAAAGCAGGTAACTGTACGTCTTTACGAGAAT
ATCGTAAATGAGGAGCTTGGAGTGTACAATGAGGACGGAAGCTTAAATCTTAATCCTAATTCACTCACAGTGCTTGATAA
CTGTGTAGTGGAGCCGGAGCTTATGAGTGCCAAGGCTTATGACAGCTTCCAGTTTGTCAGAAATGGCTTCTTCTGCGCGG
ATTGCAAGGACTCAAAGGATGGACAGCCTGTATTTAACAGAATCGTCTCATTAAAGAGCTCATTCAAGCTTCCGACAGCT
AAATAG

Upstream 100 bases:

>100_bases
ATACGCACGTATAATATACATGTACTACTTTTTCTAATTCATTGACAAAGTAAACTGATGAATTTATAATGGACACAGTA
TTATTTTCGGAGGAACATTT

Downstream 100 bases:

>100_bases
TTTTTGACTAAAAATAAACAGAAGAGAAGAATAGAGGTAAAATATGGATTTAAAGTCAGGTATTGACAAATTCGGTTTAA
ATCCTGAAGACATAAATGAT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MENEATVSKNFIEQIIEKDLAEGHCKTVKTRFPPEPNGYLHIGHAKSILLNYGLAKKYDGQFNLRFDDTNPTKERLEFVE
SIEADVKWLGADWADRKFFASNYFDKMYECAVGLIKKGKAYVSDLTPDEIREYRGTLTEAGKEDPYSKRSVEENLDLFER
MKNGEFEDGTKVLRARIDMSSSNINMRDPILYRVAHMTHHNTGDKWCVYPMYDFAHPIEDAIEGITHSICTLEFEDHRPL
YDWVVIECGFKNSPEESPKQIEFAKLYLTNVVTGKRYIKRLVEDGIVDGWDDPRLVSIAALRRRGFTPESIQNFVDLCGI
SKANSSVDYAMLEYCIREDLKAKRPRMMAVLDPVKVIIDNYPEGQVEYLEVDNNVENPELGKRKVPFTRELYVERDDFME
EPPKKYFRMFPGNEVRFMNAYFVKCNSCVKDENGNITEIHCTYDPASKGGNSPDGRKVKGTIHWVSAEYGKQVTVRLYEN
IVNEELGVYNEDGSLNLNPNSLTVLDNCVVEPELMSAKAYDSFQFVRNGFFCADCKDSKDGQPVFNRIVSLKSSFKLPTA
K

Sequences:

>Translated_561_residues
MENEATVSKNFIEQIIEKDLAEGHCKTVKTRFPPEPNGYLHIGHAKSILLNYGLAKKYDGQFNLRFDDTNPTKERLEFVE
SIEADVKWLGADWADRKFFASNYFDKMYECAVGLIKKGKAYVSDLTPDEIREYRGTLTEAGKEDPYSKRSVEENLDLFER
MKNGEFEDGTKVLRARIDMSSSNINMRDPILYRVAHMTHHNTGDKWCVYPMYDFAHPIEDAIEGITHSICTLEFEDHRPL
YDWVVIECGFKNSPEESPKQIEFAKLYLTNVVTGKRYIKRLVEDGIVDGWDDPRLVSIAALRRRGFTPESIQNFVDLCGI
SKANSSVDYAMLEYCIREDLKAKRPRMMAVLDPVKVIIDNYPEGQVEYLEVDNNVENPELGKRKVPFTRELYVERDDFME
EPPKKYFRMFPGNEVRFMNAYFVKCNSCVKDENGNITEIHCTYDPASKGGNSPDGRKVKGTIHWVSAEYGKQVTVRLYEN
IVNEELGVYNEDGSLNLNPNSLTVLDNCVVEPELMSAKAYDSFQFVRNGFFCADCKDSKDGQPVFNRIVSLKSSFKLPTA
K
>Mature_561_residues
MENEATVSKNFIEQIIEKDLAEGHCKTVKTRFPPEPNGYLHIGHAKSILLNYGLAKKYDGQFNLRFDDTNPTKERLEFVE
SIEADVKWLGADWADRKFFASNYFDKMYECAVGLIKKGKAYVSDLTPDEIREYRGTLTEAGKEDPYSKRSVEENLDLFER
MKNGEFEDGTKVLRARIDMSSSNINMRDPILYRVAHMTHHNTGDKWCVYPMYDFAHPIEDAIEGITHSICTLEFEDHRPL
YDWVVIECGFKNSPEESPKQIEFAKLYLTNVVTGKRYIKRLVEDGIVDGWDDPRLVSIAALRRRGFTPESIQNFVDLCGI
SKANSSVDYAMLEYCIREDLKAKRPRMMAVLDPVKVIIDNYPEGQVEYLEVDNNVENPELGKRKVPFTRELYVERDDFME
EPPKKYFRMFPGNEVRFMNAYFVKCNSCVKDENGNITEIHCTYDPASKGGNSPDGRKVKGTIHWVSAEYGKQVTVRLYEN
IVNEELGVYNEDGSLNLNPNSLTVLDNCVVEPELMSAKAYDSFQFVRNGFFCADCKDSKDGQPVFNRIVSLKSSFKLPTA
K

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=534, Percent_Identity=41.0112359550562, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI62241042, Length=516, Percent_Identity=33.5271317829457, Blast_Score=259, Evalue=3e-69,
Organism=Escherichia coli, GI1786895, Length=546, Percent_Identity=52.5641025641026, Blast_Score=584, Evalue=1e-168,
Organism=Escherichia coli, GI1788743, Length=316, Percent_Identity=24.6835443037975, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17543332, Length=542, Percent_Identity=38.7453874538745, Blast_Score=350, Evalue=1e-96,
Organism=Caenorhabditis elegans, GI17511007, Length=514, Percent_Identity=31.9066147859922, Blast_Score=229, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6324742, Length=566, Percent_Identity=38.5159010600707, Blast_Score=361, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6321192, Length=383, Percent_Identity=38.6422976501305, Blast_Score=273, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6324540, Length=346, Percent_Identity=26.3005780346821, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17864488, Length=556, Percent_Identity=38.6690647482014, Blast_Score=368, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24649466, Length=522, Percent_Identity=33.5249042145594, Blast_Score=250, Evalue=2e-66,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 64449; Mature: 64449

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENEATVSKNFIEQIIEKDLAEGHCKTVKTRFPPEPNGYLHIGHAKSILLNYGLAKKYDG
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEECCHHHHHHHCCCCCCCCC
QFNLRFDDTNPTKERLEFVESIEADVKWLGADWADRKFFASNYFDKMYECAVGLIKKGKA
EEEEEECCCCCHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
YVSDLTPDEIREYRGTLTEAGKEDPYSKRSVEENLDLFERMKNGEFEDGTKVLRARIDMS
HHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
SSNINMRDPILYRVAHMTHHNTGDKWCVYPMYDFAHPIEDAIEGITHSICTLEFEDHRPL
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEECHHHHCHHHHHHHHHHHHEEEEEECCCCCC
YDWVVIECGFKNSPEESPKQIEFAKLYLTNVVTGKRYIKRLVEDGIVDGWDDPRLVSIAA
EEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LRRRGFTPESIQNFVDLCGISKANSSVDYAMLEYCIREDLKAKRPRMMAVLDPVKVIIDN
HHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
YPEGQVEYLEVDNNVENPELGKRKVPFTRELYVERDDFMEEPPKKYFRMFPGNEVRFMNA
CCCCCEEEEEECCCCCCCCCCCCCCCCHHHHEECCHHHHCCCCHHHHHCCCCCCEEEEEE
YFVKCNSCVKDENGNITEIHCTYDPASKGGNSPDGRKVKGTIHWVSAEYGKQVTVRLYEN
EEEEECCCCCCCCCCEEEEEEEECCHHCCCCCCCCCEEEEEEEEEECCCCCEEHHHHHHH
IVNEELGVYNEDGSLNLNPNSLTVLDNCVVEPELMSAKAYDSFQFVRNGFFCADCKDSKD
HHHHHCCCCCCCCCEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCC
GQPVFNRIVSLKSSFKLPTAK
CCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MENEATVSKNFIEQIIEKDLAEGHCKTVKTRFPPEPNGYLHIGHAKSILLNYGLAKKYDG
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEECCHHHHHHHCCCCCCCCC
QFNLRFDDTNPTKERLEFVESIEADVKWLGADWADRKFFASNYFDKMYECAVGLIKKGKA
EEEEEECCCCCHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
YVSDLTPDEIREYRGTLTEAGKEDPYSKRSVEENLDLFERMKNGEFEDGTKVLRARIDMS
HHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
SSNINMRDPILYRVAHMTHHNTGDKWCVYPMYDFAHPIEDAIEGITHSICTLEFEDHRPL
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEECHHHHCHHHHHHHHHHHHEEEEEECCCCCC
YDWVVIECGFKNSPEESPKQIEFAKLYLTNVVTGKRYIKRLVEDGIVDGWDDPRLVSIAA
EEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LRRRGFTPESIQNFVDLCGISKANSSVDYAMLEYCIREDLKAKRPRMMAVLDPVKVIIDN
HHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
YPEGQVEYLEVDNNVENPELGKRKVPFTRELYVERDDFMEEPPKKYFRMFPGNEVRFMNA
CCCCCEEEEEECCCCCCCCCCCCCCCCHHHHEECCHHHHCCCCHHHHHCCCCCCEEEEEE
YFVKCNSCVKDENGNITEIHCTYDPASKGGNSPDGRKVKGTIHWVSAEYGKQVTVRLYEN
EEEEECCCCCCCCCCEEEEEEEECCHHCCCCCCCCCEEEEEEEEEECCCCCEEHHHHHHH
IVNEELGVYNEDGSLNLNPNSLTVLDNCVVEPELMSAKAYDSFQFVRNGFFCADCKDSKD
HHHHHCCCCCCCCCEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCC
GQPVFNRIVSLKSSFKLPTAK
CCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA