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The map label for this gene is coaE [H]

Identifier: 238923923

GI number: 238923923

Start: 1446586

End: 1447227

Strand: Direct

Name: coaE [H]

Synonym: EUBREC_1561

Alternate gene names: 238923923

Gene position: 1446586-1447227 (Clockwise)

Preceding gene: 238923922

Following gene: 238923924

Centisome position: 41.93

GC content: 42.06

Gene sequence:

>642_bases
ATGACTGGTATGATGCGCATTGATGACAGAAAAGGAAACAGTATGATTTTTATAGGAATAACAGGTGGTGTAGGTGCCGG
AAAATCGGCAGTGCTTAGCTATCTTAGGGAACTTGATGGCGTAAGGGTCATGCTCTCCGATGAGATAGCACATGAGCTGA
TGGAGCCGGGAAGCGACTGCTACAACAGATTAAAGGAATTGTTTGCAGAGGAACCGATATGGCTTGAGGACGGGCATTTT
GACAGACCGGCACTTGCCGGAGTGATTTTTTCGAATGATAAAAAAAGAGAGCTTTTAAACGAAGTAGTGCATCCGGCAGT
AAAGGAATATGTGCTTAATGCAGTTAAAGAGGCAAAAAAAGAAGGTCTTTTTATGCTTGTGCTTGAAGCAGCACTCCTTA
TAGAGGAGGGATATGGTGAAATCTGCGACGAGCTGTGGTATATTTATGCAAGTGAAGAAGTCAGAAGAAAAAGACTTAAG
TCATCACGCGGATATTCAGATGAGAAGATAGATAGTATCTTTGCAAGCCAGCTTAAAGAAGCTGAGTACAGAAGGCACTG
CAAGGAGGTTATCGATAATGATGGAGATATCGAAAACACGATAGCTTCAATAAATAAAGCGCTTAGCAAATACAAGGAGT
AG

Upstream 100 bases:

>100_bases
AAGGAAGCTGAGAAGGATAAAGTGATTAAGCTTCTGGAGAAAGAGATGCGTGGTGCGGTGGACATGAAGGTATCCATGGA
GGTGGGCACCGAGTGTGGCT

Downstream 100 bases:

>100_bases
TGGAAATGAATAATGTATTCGGTTTGGATATTGGTACAAGAAATGTTGTAGGAACTGTCGGCTATCAGACTGATGACAAG
GAATTTGTGGTTACAGCACA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTGMMRIDDRKGNSMIFIGITGGVGAGKSAVLSYLRELDGVRVMLSDEIAHELMEPGSDCYNRLKELFAEEPIWLEDGHF
DRPALAGVIFSNDKKRELLNEVVHPAVKEYVLNAVKEAKKEGLFMLVLEAALLIEEGYGEICDELWYIYASEEVRRKRLK
SSRGYSDEKIDSIFASQLKEAEYRRHCKEVIDNDGDIENTIASINKALSKYKE

Sequences:

>Translated_213_residues
MTGMMRIDDRKGNSMIFIGITGGVGAGKSAVLSYLRELDGVRVMLSDEIAHELMEPGSDCYNRLKELFAEEPIWLEDGHF
DRPALAGVIFSNDKKRELLNEVVHPAVKEYVLNAVKEAKKEGLFMLVLEAALLIEEGYGEICDELWYIYASEEVRRKRLK
SSRGYSDEKIDSIFASQLKEAEYRRHCKEVIDNDGDIENTIASINKALSKYKE
>Mature_212_residues
TGMMRIDDRKGNSMIFIGITGGVGAGKSAVLSYLRELDGVRVMLSDEIAHELMEPGSDCYNRLKELFAEEPIWLEDGHFD
RPALAGVIFSNDKKRELLNEVVHPAVKEYVLNAVKEAKKEGLFMLVLEAALLIEEGYGEICDELWYIYASEEVRRKRLKS
SRGYSDEKIDSIFASQLKEAEYRRHCKEVIDNDGDIENTIASINKALSKYKE

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=183, Percent_Identity=26.2295081967213, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI191252795, Length=183, Percent_Identity=26.2295081967213, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI110227607, Length=166, Percent_Identity=28.9156626506024, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227605, Length=195, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227603, Length=195, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227601, Length=195, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI205277394, Length=195, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1786292, Length=179, Percent_Identity=27.3743016759777, Blast_Score=74, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17554944, Length=207, Percent_Identity=29.951690821256, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25143409, Length=149, Percent_Identity=35.5704697986577, Blast_Score=73, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6320402, Length=204, Percent_Identity=28.4313725490196, Blast_Score=90, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24658602, Length=187, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24644728, Length=198, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 24174; Mature: 24043

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGMMRIDDRKGNSMIFIGITGGVGAGKSAVLSYLRELDGVRVMLSDEIAHELMEPGSDC
CCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCHHH
YNRLKELFAEEPIWLEDGHFDRPALAGVIFSNDKKRELLNEVVHPAVKEYVLNAVKEAKK
HHHHHHHHCCCCCEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGLFMLVLEAALLIEEGYGEICDELWYIYASEEVRRKRLKSSRGYSDEKIDSIFASQLKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AEYRRHCKEVIDNDGDIENTIASINKALSKYKE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGMMRIDDRKGNSMIFIGITGGVGAGKSAVLSYLRELDGVRVMLSDEIAHELMEPGSDC
CCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCHHH
YNRLKELFAEEPIWLEDGHFDRPALAGVIFSNDKKRELLNEVVHPAVKEYVLNAVKEAKK
HHHHHHHHCCCCCEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGLFMLVLEAALLIEEGYGEICDELWYIYASEEVRRKRLKSSRGYSDEKIDSIFASQLKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AEYRRHCKEVIDNDGDIENTIASINKALSKYKE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]