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The map label for this gene is gapA1 [H]

Identifier: 238923894

GI number: 238923894

Start: 1405793

End: 1406851

Strand: Direct

Name: gapA1 [H]

Synonym: EUBREC_1522

Alternate gene names: 238923894

Gene position: 1405793-1406851 (Clockwise)

Preceding gene: 238923893

Following gene: 238923895

Centisome position: 40.75

GC content: 42.49

Gene sequence:

>1059_bases
ATGTCCCTAAAAATACTTTTTACAATTCTAGGAGGAATTAAAATGGCAGTAAGAGTAGCAATCAACGGATTTGGTCGTAT
CGGACGTCTTGCTTTCAGACAGATGTTTGGAGCTGAGGGATACGAGGTAGTAGCTATCAACGACTTAACAAGCCCAAAAA
TGTTAGCACACTTATTAAAGTATGATTCATCACAGGGTAAATACGAGCATGCAGATGAGGTTTCTGCAAGCGATGATTCT
ATCACAGTTTGTGGTAAGGAAATCAAAATTTACGCATTCCCAGATGCAAACAATTGCCCATGGGGAGAGTTAAAGGTTGA
CGTTGTACTTGAGTGCTCTGGATTCTATACATCAAAAGAGAAGGCTCAGGCTCATATCAATGCTGGAGCTCGTAAGGTAG
TTATCTCTGCACCAGCAGGAAATGACCTTCCTACAATCGTTTACAATACAAACCATGAGACACTTAAGGCTTCTGATACA
ATCATCTCAGCAGCTTCTTGTACAACAAACTGCTTAGCACCAATGGCAGATGCACTTAACAAGTACGCTCCAATCCAGTC
TGGTATCATGGTAACAATCCATGCTTACACAGGAGATCAGATGACTCTTGACGGACCACAGAGAAAGGGAGACCTTCGTC
GTTCACGTGCAGCAGCAGTTAATATCGTTCCTAACTCAACAGGAGCAGCTAAGGCAATCGGCCTTGTTATCCCAGAGTTA
AACGGAAAGTTAATCGGATCTGCACAGCGTGTTCCTACACCAACAGGATCTACAACAATCCTTACAGCAGTTGTTAAGAA
AGCAGGCGTTACAAAAGAGGATATCAACGCAGCTATGAAGGCAGCAGCTAACGAGTCATTCGGTTACAACGAGGATGAGA
TCGTATCTTCAGATATCGTTGGAATGAGATTTGGTTCATTATTCGATGCAACACAGACAATGGTTAACCAGGTTTCTGAC
GATCTGTACGAGGTACAGGTTGTTTCTTGGTATGATAACGAGAACAGCTACACATCTCAGATGGTTCGTACAATCAAGTA
CTTCTCAGAGTTAGCTTAA

Upstream 100 bases:

>100_bases
AATGTGTGTAAATGAAAATATTTAGTGAAAATTTTAACAAACGCAAATAAAGTACTTGAACCTTTGAGAATTATTCGCTA
TAATAAAAGCATCTTAGGGC

Downstream 100 bases:

>100_bases
TTCTTGTACCCACAAGAACAGTATATCTCAAGACTACTCAAGGGGCGCGGTCTTAATTGAACCGCGCCTCTTTTTTAAAG
CATGGCTATTTCTTTTGAAT

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH 1 [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSLKILFTILGGIKMAVRVAINGFGRIGRLAFRQMFGAEGYEVVAINDLTSPKMLAHLLKYDSSQGKYEHADEVSASDDS
ITVCGKEIKIYAFPDANNCPWGELKVDVVLECSGFYTSKEKAQAHINAGARKVVISAPAGNDLPTIVYNTNHETLKASDT
IISAASCTTNCLAPMADALNKYAPIQSGIMVTIHAYTGDQMTLDGPQRKGDLRRSRAAAVNIVPNSTGAAKAIGLVIPEL
NGKLIGSAQRVPTPTGSTTILTAVVKKAGVTKEDINAAMKAAANESFGYNEDEIVSSDIVGMRFGSLFDATQTMVNQVSD
DLYEVQVVSWYDNENSYTSQMVRTIKYFSELA

Sequences:

>Translated_352_residues
MSLKILFTILGGIKMAVRVAINGFGRIGRLAFRQMFGAEGYEVVAINDLTSPKMLAHLLKYDSSQGKYEHADEVSASDDS
ITVCGKEIKIYAFPDANNCPWGELKVDVVLECSGFYTSKEKAQAHINAGARKVVISAPAGNDLPTIVYNTNHETLKASDT
IISAASCTTNCLAPMADALNKYAPIQSGIMVTIHAYTGDQMTLDGPQRKGDLRRSRAAAVNIVPNSTGAAKAIGLVIPEL
NGKLIGSAQRVPTPTGSTTILTAVVKKAGVTKEDINAAMKAAANESFGYNEDEIVSSDIVGMRFGSLFDATQTMVNQVSD
DLYEVQVVSWYDNENSYTSQMVRTIKYFSELA
>Mature_351_residues
SLKILFTILGGIKMAVRVAINGFGRIGRLAFRQMFGAEGYEVVAINDLTSPKMLAHLLKYDSSQGKYEHADEVSASDDSI
TVCGKEIKIYAFPDANNCPWGELKVDVVLECSGFYTSKEKAQAHINAGARKVVISAPAGNDLPTIVYNTNHETLKASDTI
ISAASCTTNCLAPMADALNKYAPIQSGIMVTIHAYTGDQMTLDGPQRKGDLRRSRAAAVNIVPNSTGAAKAIGLVIPELN
GKLIGSAQRVPTPTGSTTILTAVVKKAGVTKEDINAAMKAAANESFGYNEDEIVSSDIVGMRFGSLFDATQTMVNQVSDD
LYEVQVVSWYDNENSYTSQMVRTIKYFSELA

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=335, Percent_Identity=41.7910447761194, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI7669492, Length=338, Percent_Identity=41.1242603550296, Blast_Score=236, Evalue=2e-62,
Organism=Escherichia coli, GI1788079, Length=340, Percent_Identity=45.5882352941176, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1789295, Length=338, Percent_Identity=39.3491124260355, Blast_Score=219, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17534677, Length=342, Percent_Identity=43.859649122807, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI32566163, Length=345, Percent_Identity=44.6376811594203, Blast_Score=250, Evalue=7e-67,
Organism=Caenorhabditis elegans, GI17568413, Length=345, Percent_Identity=44.6376811594203, Blast_Score=250, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI17534679, Length=342, Percent_Identity=43.859649122807, Blast_Score=250, Evalue=8e-67,
Organism=Saccharomyces cerevisiae, GI6322409, Length=339, Percent_Identity=44.8377581120944, Blast_Score=270, Evalue=4e-73,
Organism=Saccharomyces cerevisiae, GI6321631, Length=339, Percent_Identity=45.1327433628319, Blast_Score=266, Evalue=4e-72,
Organism=Saccharomyces cerevisiae, GI6322468, Length=339, Percent_Identity=44.5427728613569, Blast_Score=262, Evalue=6e-71,
Organism=Drosophila melanogaster, GI19922412, Length=333, Percent_Identity=42.9429429429429, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=40.8955223880597, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=40.8955223880597, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI85725000, Length=335, Percent_Identity=40.2985074626866, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI22023983, Length=335, Percent_Identity=40.2985074626866, Blast_Score=233, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37858; Mature: 37727

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00071 GAPDH ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKILFTILGGIKMAVRVAINGFGRIGRLAFRQMFGAEGYEVVAINDLTSPKMLAHLLK
CCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHH
YDSSQGKYEHADEVSASDDSITVCGKEIKIYAFPDANNCPWGELKVDVVLECSGFYTSKE
CCCCCCCCCCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCEEEEEEEEECCCCCCHH
KAQAHINAGARKVVISAPAGNDLPTIVYNTNHETLKASDTIISAASCTTNCLAPMADALN
HHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCEEECCCCEEEHHHHHHHHHHHHHHHHH
KYAPIQSGIMVTIHAYTGDQMTLDGPQRKGDLRRSRAAAVNIVPNSTGAAKAIGLVIPEL
HCCCCCCCEEEEEEEECCCEEEECCCCCCCHHHHCCCEEEEEEECCCCCHHEEEEEEECC
NGKLIGSAQRVPTPTGSTTILTAVVKKAGVTKEDINAAMKAAANESFGYNEDEIVSSDIV
CCEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCHH
GMRFGSLFDATQTMVNQVSDDLYEVQVVSWYDNENSYTSQMVRTIKYFSELA
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLKILFTILGGIKMAVRVAINGFGRIGRLAFRQMFGAEGYEVVAINDLTSPKMLAHLLK
CEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHH
YDSSQGKYEHADEVSASDDSITVCGKEIKIYAFPDANNCPWGELKVDVVLECSGFYTSKE
CCCCCCCCCCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCEEEEEEEEECCCCCCHH
KAQAHINAGARKVVISAPAGNDLPTIVYNTNHETLKASDTIISAASCTTNCLAPMADALN
HHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCEEECCCCEEEHHHHHHHHHHHHHHHHH
KYAPIQSGIMVTIHAYTGDQMTLDGPQRKGDLRRSRAAAVNIVPNSTGAAKAIGLVIPEL
HCCCCCCCEEEEEEEECCCEEEECCCCCCCHHHHCCCEEEEEEECCCCCHHEEEEEEECC
NGKLIGSAQRVPTPTGSTTILTAVVKKAGVTKEDINAAMKAAANESFGYNEDEIVSSDIV
CCEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCHH
GMRFGSLFDATQTMVNQVSDDLYEVQVVSWYDNENSYTSQMVRTIKYFSELA
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA