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The map label for this gene is pncB [H]

Identifier: 238923891

GI number: 238923891

Start: 1402712

End: 1404007

Strand: Direct

Name: pncB [H]

Synonym: EUBREC_1519

Alternate gene names: 238923891

Gene position: 1402712-1404007 (Clockwise)

Preceding gene: 238923890

Following gene: 238923893

Centisome position: 40.66

GC content: 43.67

Gene sequence:

>1296_bases
TTGATATTTGATAGTCGCAGTGGTAAAATCAAGACTAAAATTACCGGTAGCAAATGGTTTGAAAGAAAAGAGGACATAAA
ACAGATGAGATTGCCACAAATAATAAACAGCCTTCTTGAGACTGATATGTATAAATTCAGCATGGGACAGACGATTTTCC
ATCAGTTCACAAGCTATAAAACGACATGGACCTTCAAGTGCCGAAATAAAGACGTGCATTTTACAGATGAGATGGTCGAG
GAGATAAAGGAACAGGTGCAGGCCTTCTGTCAGCTTCGTTTTACGGAGGAAGAGCTTGAATATCTTGATAACATCACCTG
GATAAAAGGTACATATGTTGATTTTTTAAGACTCTGGCAGCCGAGATATGAGGAGTTTACCATCACAACAGATGCACCGT
GTGGGCTGGCAATCGATGCAGCCGGCACGTGGCTCAATACTTCGATGTATGAGATTCCGGTGCTTGCTATTGTAAATGAA
GTGTACTTCCGTATGGCATATGATTATGATGTGCTGCTTAAGCAGTTTAAGCGCAGGCTTGATGAGAAGGTGCGTCTGCT
CGAGGAGGATACCTACAGGCTTAGCGATTTCAGTGAATTTGGACTAAGACGCCGTCTGTCTGCTGAGGCGCAGGAGATGG
CTGTAAAGGCAATCGCAGAGGTTGAGCTGCCAGCAGATTCACACTTTATTGGTACATCAAACGTATATCTTGCGAAGAAA
TTCAATTTAAAGCCGGTTGGAACAATGGCTCATGAGTGGATTATGTGTACAGGACAGGGCAATCACAAGCATAATCCGGC
ATATTCAAACTGGTACGCACTCGATGCATGGGTTAAGGAGTATGGTATATTAAACGGTATTGCGCTTACTGACACCATAA
CAACAGACTGCTTCCTGCGTGATTTTCAGCTCACCTATGCGACACTTTTTTCGGGAGTGCGTCATGATAGCGGAGATCCG
TACGAGTGGGGAGACAAGATGATAGCCCACTACAACAGTCTGGGAATTAATCCAAGGACAAAGACACTTTTGTTCAGCGA
CAGCCTGGATTTCGAGCGTGCGACTGCATTGTATGATTATTTCAAGGATAAGGCAAAGGTTGCATTCGGTATAGGAACCT
TTATCAGTAACGACACTGATGAGGAAGCACTCAACATAGTTATGAAGACCACCAAGTGTAATGGCATGGATGTGGCAAAG
ATTTCCGACGTGGCAGGCAAGGGTATGTGCAAGAATCCGGATTATGTCGATTACCTGAACAGGTGTATTGATTACAGGAT
GAAGAATGATAAATGA

Upstream 100 bases:

>100_bases
GGTCACGGTTAGTGGCTTTCATGGGAGTTTTTATTTTGGAACCAGTGAATATGCTGACGGAAAAAAAATAAATTGAAGGT
AATTAAACACGTGTGTCTGC

Downstream 100 bases:

>100_bases
TAAATGATGGCATGAGGGGGCAAAGATATTTTGCCCCTTTAATTATGTGATTGAATTGCAAGAAATGTGTAAACAAAACA
AAAAATATATAAAATATCAG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MIFDSRSGKIKTKITGSKWFERKEDIKQMRLPQIINSLLETDMYKFSMGQTIFHQFTSYKTTWTFKCRNKDVHFTDEMVE
EIKEQVQAFCQLRFTEEELEYLDNITWIKGTYVDFLRLWQPRYEEFTITTDAPCGLAIDAAGTWLNTSMYEIPVLAIVNE
VYFRMAYDYDVLLKQFKRRLDEKVRLLEEDTYRLSDFSEFGLRRRLSAEAQEMAVKAIAEVELPADSHFIGTSNVYLAKK
FNLKPVGTMAHEWIMCTGQGNHKHNPAYSNWYALDAWVKEYGILNGIALTDTITTDCFLRDFQLTYATLFSGVRHDSGDP
YEWGDKMIAHYNSLGINPRTKTLLFSDSLDFERATALYDYFKDKAKVAFGIGTFISNDTDEEALNIVMKTTKCNGMDVAK
ISDVAGKGMCKNPDYVDYLNRCIDYRMKNDK

Sequences:

>Translated_431_residues
MIFDSRSGKIKTKITGSKWFERKEDIKQMRLPQIINSLLETDMYKFSMGQTIFHQFTSYKTTWTFKCRNKDVHFTDEMVE
EIKEQVQAFCQLRFTEEELEYLDNITWIKGTYVDFLRLWQPRYEEFTITTDAPCGLAIDAAGTWLNTSMYEIPVLAIVNE
VYFRMAYDYDVLLKQFKRRLDEKVRLLEEDTYRLSDFSEFGLRRRLSAEAQEMAVKAIAEVELPADSHFIGTSNVYLAKK
FNLKPVGTMAHEWIMCTGQGNHKHNPAYSNWYALDAWVKEYGILNGIALTDTITTDCFLRDFQLTYATLFSGVRHDSGDP
YEWGDKMIAHYNSLGINPRTKTLLFSDSLDFERATALYDYFKDKAKVAFGIGTFISNDTDEEALNIVMKTTKCNGMDVAK
ISDVAGKGMCKNPDYVDYLNRCIDYRMKNDK
>Mature_431_residues
MIFDSRSGKIKTKITGSKWFERKEDIKQMRLPQIINSLLETDMYKFSMGQTIFHQFTSYKTTWTFKCRNKDVHFTDEMVE
EIKEQVQAFCQLRFTEEELEYLDNITWIKGTYVDFLRLWQPRYEEFTITTDAPCGLAIDAAGTWLNTSMYEIPVLAIVNE
VYFRMAYDYDVLLKQFKRRLDEKVRLLEEDTYRLSDFSEFGLRRRLSAEAQEMAVKAIAEVELPADSHFIGTSNVYLAKK
FNLKPVGTMAHEWIMCTGQGNHKHNPAYSNWYALDAWVKEYGILNGIALTDTITTDCFLRDFQLTYATLFSGVRHDSGDP
YEWGDKMIAHYNSLGINPRTKTLLFSDSLDFERATALYDYFKDKAKVAFGIGTFISNDTDEEALNIVMKTTKCNGMDVAK
ISDVAGKGMCKNPDYVDYLNRCIDYRMKNDK

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=400, Percent_Identity=39.5, Blast_Score=282, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6324783, Length=404, Percent_Identity=36.6336633663366, Blast_Score=232, Evalue=8e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 50121; Mature: 50121

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFDSRSGKIKTKITGSKWFERKEDIKQMRLPQIINSLLETDMYKFSMGQTIFHQFTSYK
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TTWTFKCRNKDVHFTDEMVEEIKEQVQAFCQLRFTEEELEYLDNITWIKGTYVDFLRLWQ
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEECHHHHHHHHHHC
PRYEEFTITTDAPCGLAIDAAGTWLNTSMYEIPVLAIVNEVYFRMAYDYDVLLKQFKRRL
CCCCEEEEECCCCCCEEEECCCCEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
DEKVRLLEEDTYRLSDFSEFGLRRRLSAEAQEMAVKAIAEVELPADSHFIGTSNVYLAKK
HHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEECCCCEEEEEE
FNLKPVGTMAHEWIMCTGQGNHKHNPAYSNWYALDAWVKEYGILNGIALTDTITTDCFLR
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECHHHHHHHHH
DFQLTYATLFSGVRHDSGDPYEWGDKMIAHYNSLGINPRTKTLLFSDSLDFERATALYDY
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHH
FKDKAKVAFGIGTFISNDTDEEALNIVMKTTKCNGMDVAKISDVAGKGMCKNPDYVDYLN
HHCCCEEEEEEHHHHCCCCCHHHHHHHEEECCCCCCCHHHHHHHCCCCCCCCCCHHHHHH
RCIDYRMKNDK
HHHHHHCCCCC
>Mature Secondary Structure
MIFDSRSGKIKTKITGSKWFERKEDIKQMRLPQIINSLLETDMYKFSMGQTIFHQFTSYK
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TTWTFKCRNKDVHFTDEMVEEIKEQVQAFCQLRFTEEELEYLDNITWIKGTYVDFLRLWQ
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEECHHHHHHHHHHC
PRYEEFTITTDAPCGLAIDAAGTWLNTSMYEIPVLAIVNEVYFRMAYDYDVLLKQFKRRL
CCCCEEEEECCCCCCEEEECCCCEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
DEKVRLLEEDTYRLSDFSEFGLRRRLSAEAQEMAVKAIAEVELPADSHFIGTSNVYLAKK
HHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEECCCCEEEEEE
FNLKPVGTMAHEWIMCTGQGNHKHNPAYSNWYALDAWVKEYGILNGIALTDTITTDCFLR
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECHHHHHHHHH
DFQLTYATLFSGVRHDSGDPYEWGDKMIAHYNSLGINPRTKTLLFSDSLDFERATALYDY
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHH
FKDKAKVAFGIGTFISNDTDEEALNIVMKTTKCNGMDVAKISDVAGKGMCKNPDYVDYLN
HHCCCEEEEEEHHHHCCCCCHHHHHHHEEECCCCCCCHHHHHHHCCCCCCCCCCHHHHHH
RCIDYRMKNDK
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA