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The map label for this gene is ackA

Identifier: 238923866

GI number: 238923866

Start: 1375355

End: 1376548

Strand: Direct

Name: ackA

Synonym: EUBREC_1494

Alternate gene names: 238923866

Gene position: 1375355-1376548 (Clockwise)

Preceding gene: 238923864

Following gene: 238923867

Centisome position: 39.87

GC content: 45.56

Gene sequence:

>1194_bases
ATGAATGTATTAGTAATTAATTGCGGTAGTTCATCACTGAAATACCAGCTCATCAATTCAGATTCAGAGGAGGTACTTGC
AAAAGGACTCTGCGAGAGAATCGGAATCGATGGCAGACTCGTATATCAGAAAGAGGGTCTTGATAAGGAAATCACAGAGG
CACCTATGCCAACACATAAAGAGGCCATCCAGATGGTACTCGATGCACTTGTAAATCCAAAGACAGGCGCAGTAAAATCA
CTTGCAGAGATCGATGCAGTAGGACATCGTGTAGTGCACGGCGGAGAAAAATTCTCAGACTCAGTAGTCATCACAGAGGA
AGTAATCGCACAGGTAGAGGAGTGCAACGACCTTGCACCTCTTCACAACCCTGCAAATATTATCGGAATCAGAGCATGCC
AGGCACTTATGCCAAATGTACCAATGGTAGGAGTATTTGATACAGCCTTCCATCAGACAATGCCTGAGAAAGCATATCTC
TACGGCCTTCCATATGAGTACTATGAGAAGTACAAGGTAAGAAGATACGGCTTCCACGGCACAAGCCACAGCTTCGTATC
AAAGGAGGCAGCAAGCTACCTTGGAATGGACTTAAACAACTCAAAGATTATCGTAGCACACCTTGGAAACGGAGCTTCAG
TCAGCGCAGTATTAAACGGTAAATGCGTAGATACATCAATGGGACTTACACCACTTGAGGGACTCGTAATGGGAACACGT
TCAGGTGATATCGACCCATCAATCATGGAGTTCATTGCAAAGAAAGAAAACCTTGACATCGATGGTGTGATGAATGTGCT
CAACAAGAAGTCAGGAGTAGCCGGCATGTCAGGAGTATCAAGCGACTTCAGAGATCTTGAGGCAGCCTACAATGAGGGCA
ACGAGCGTGCTATTGCAGCAGTAGAAGTATTCAGCTACAGGGTAGCAAAATACATCGGAGCATATGCAGCAGCAATGAAC
GGAGTAGATGCTATCGCATTCACAGCAGGAATCGGTGAGAACACAAGCTTTGTAAGAGAAAAAATCATGGCATATTTAGG
TTACCTGGGCATAAAGATCGACCGTGTAACAAACGACAAGACACGCGGCGTGGAGGCACTTATCTCAACAGCAGACTCAA
GCGTAAAGGTATGCGTCATCCCTACAAACGAGGAGCTTGCAATCTGCCGCGAGACAGTAAAGCTTGTTGGCTAA

Upstream 100 bases:

>100_bases
AGTTCAAAACCATAATACCACAAAAACACCCTTGTCGCATTTGAAAAATAAGTTTATACTAACAATAGTATTGTAATTTT
AAACCAAAGGAGACAAAACA

Downstream 100 bases:

>100_bases
TAAAAAGCAAAAAGTTGTGGATAAATTATAAAATTTTGTTGACAAACACCACTCCAATATGTATAATTGGTTAGGTGTGA
ATAGGAGAGAACTATGATTG

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNVLVINCGSSSLKYQLINSDSEEVLAKGLCERIGIDGRLVYQKEGLDKEITEAPMPTHKEAIQMVLDALVNPKTGAVKS
LAEIDAVGHRVVHGGEKFSDSVVITEEVIAQVEECNDLAPLHNPANIIGIRACQALMPNVPMVGVFDTAFHQTMPEKAYL
YGLPYEYYEKYKVRRYGFHGTSHSFVSKEAASYLGMDLNNSKIIVAHLGNGASVSAVLNGKCVDTSMGLTPLEGLVMGTR
SGDIDPSIMEFIAKKENLDIDGVMNVLNKKSGVAGMSGVSSDFRDLEAAYNEGNERAIAAVEVFSYRVAKYIGAYAAAMN
GVDAIAFTAGIGENTSFVREKIMAYLGYLGIKIDRVTNDKTRGVEALISTADSSVKVCVIPTNEELAICRETVKLVG

Sequences:

>Translated_397_residues
MNVLVINCGSSSLKYQLINSDSEEVLAKGLCERIGIDGRLVYQKEGLDKEITEAPMPTHKEAIQMVLDALVNPKTGAVKS
LAEIDAVGHRVVHGGEKFSDSVVITEEVIAQVEECNDLAPLHNPANIIGIRACQALMPNVPMVGVFDTAFHQTMPEKAYL
YGLPYEYYEKYKVRRYGFHGTSHSFVSKEAASYLGMDLNNSKIIVAHLGNGASVSAVLNGKCVDTSMGLTPLEGLVMGTR
SGDIDPSIMEFIAKKENLDIDGVMNVLNKKSGVAGMSGVSSDFRDLEAAYNEGNERAIAAVEVFSYRVAKYIGAYAAAMN
GVDAIAFTAGIGENTSFVREKIMAYLGYLGIKIDRVTNDKTRGVEALISTADSSVKVCVIPTNEELAICRETVKLVG
>Mature_397_residues
MNVLVINCGSSSLKYQLINSDSEEVLAKGLCERIGIDGRLVYQKEGLDKEITEAPMPTHKEAIQMVLDALVNPKTGAVKS
LAEIDAVGHRVVHGGEKFSDSVVITEEVIAQVEECNDLAPLHNPANIIGIRACQALMPNVPMVGVFDTAFHQTMPEKAYL
YGLPYEYYEKYKVRRYGFHGTSHSFVSKEAASYLGMDLNNSKIIVAHLGNGASVSAVLNGKCVDTSMGLTPLEGLVMGTR
SGDIDPSIMEFIAKKENLDIDGVMNVLNKKSGVAGMSGVSSDFRDLEAAYNEGNERAIAAVEVFSYRVAKYIGAYAAAMN
GVDAIAFTAGIGENTSFVREKIMAYLGYLGIKIDRVTNDKTRGVEALISTADSSVKVCVIPTNEELAICRETVKLVG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=394, Percent_Identity=46.1928934010152, Blast_Score=357, Evalue=1e-99,
Organism=Escherichia coli, GI1788633, Length=398, Percent_Identity=45.7286432160804, Blast_Score=343, Evalue=9e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACKA_EUBR3 (C4Z917)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002937382.1
- GeneID:   7963859
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_1494
- ProtClustDB:   PRK00180
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 42822; Mature: 42822

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLVINCGSSSLKYQLINSDSEEVLAKGLCERIGIDGRLVYQKEGLDKEITEAPMPTHK
CEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCHH
EAIQMVLDALVNPKTGAVKSLAEIDAVGHRVVHGGEKFSDSVVITEEVIAQVEECNDLAP
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCCC
LHNPANIIGIRACQALMPNVPMVGVFDTAFHQTMPEKAYLYGLPYEYYEKYKVRRYGFHG
CCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCEEEECCCHHHHHHHHHHEECCCC
TSHSFVSKEAASYLGMDLNNSKIIVAHLGNGASVSAVLNGKCVDTSMGLTPLEGLVMGTR
CCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCEEEECCCCCCCCCCEEEECC
SGDIDPSIMEFIAKKENLDIDGVMNVLNKKSGVAGMSGVSSDFRDLEAAYNEGNERAIAA
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEHH
VEVFSYRVAKYIGAYAAAMNGVDAIAFTAGIGENTSFVREKIMAYLGYLGIKIDRVTNDK
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCEEEEECCCCH
TRGVEALISTADSSVKVCVIPTNEELAICRETVKLVG
HHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNVLVINCGSSSLKYQLINSDSEEVLAKGLCERIGIDGRLVYQKEGLDKEITEAPMPTHK
CEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCHH
EAIQMVLDALVNPKTGAVKSLAEIDAVGHRVVHGGEKFSDSVVITEEVIAQVEECNDLAP
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCCC
LHNPANIIGIRACQALMPNVPMVGVFDTAFHQTMPEKAYLYGLPYEYYEKYKVRRYGFHG
CCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCEEEECCCHHHHHHHHHHEECCCC
TSHSFVSKEAASYLGMDLNNSKIIVAHLGNGASVSAVLNGKCVDTSMGLTPLEGLVMGTR
CCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCEEEECCCCCCCCCCEEEECC
SGDIDPSIMEFIAKKENLDIDGVMNVLNKKSGVAGMSGVSSDFRDLEAAYNEGNERAIAA
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEHH
VEVFSYRVAKYIGAYAAAMNGVDAIAFTAGIGENTSFVREKIMAYLGYLGIKIDRVTNDK
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCEEEEECCCCH
TRGVEALISTADSSVKVCVIPTNEELAICRETVKLVG
HHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA