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The map label for this gene is engD [H]

Identifier: 238923804

GI number: 238923804

Start: 1311801

End: 1312901

Strand: Direct

Name: engD [H]

Synonym: EUBREC_1427

Alternate gene names: 238923804

Gene position: 1311801-1312901 (Clockwise)

Preceding gene: 238923803

Following gene: 238923805

Centisome position: 38.03

GC content: 46.41

Gene sequence:

>1101_bases
ATGAAACTCGGAATCGTCGGACTTCCGAACGTCGGAAAGTCTACATTATTCAACTCACTCACAAAGGCAGGAGCGCTTTC
AGCAAACTATCCTTTTGCCACAATCGACCCAAACGTAGGTATTGTTTCAGTGCCTGACGAGAGAATCGTAAAGCTCGGAG
AGCTCTATCACACAAAGAAGGTTACACCTGCAACAATCGAATTTGTTGATATCGCAGGTCTTGTGAAGGGAGCCAGTAAG
GGTGAGGGACTTGGAAACCAGTTCCTTGCAAATATCCGTGAGGTAGATGCAATCGTACACGTAGTGCGCTGCTTTGAGGA
TACAAACATTATCCATGTAGATGGCTCTGTAGATCCTGCAAGAGATATCGAGACAATCAATCTTGAGCTTATTTTCTCGG
ATGTTGAGATTCTTGACAGGCGAATTGCAAAGATTGCAAAGCAGGCAAGAATGGACAAGACACTTGCAAAGGAGCTTGAG
CTTGTTGAGGCAGTAAAGGCTCATCTTGAGGACGGAAAGATGGCCAGAACCTTTGAAGTGCCTGATGATGAGGATGCACA
GCTTTGGTTCAAGGGATATAATCTCCTTACAGCAAAGCCTACCATCTACGCAGCAAACGTATCAGAGGACGACCTCGCAG
ATGACGGCGCAAGCAATCCGCATGTTGCAAAGGTAAGAGAAATGGCAAAGGAAGAGGGCGCAGAGGTATTTGTTATCTGT
GCACAGATTGAGCAGGAGCTTGCAGATCTCGATGAGGACGAAAAGAAGGAGTACCTTGAGGATTTAGGTGTTGAGTCAAG
CGGTCTCGATAAGCTTGTAGCAGCCAGCTATTCACTTCTCGGACTTATTTCCTTCCTCACAGCAGGAGAGGATGAGTGCC
GTGCATGGACTATAAAGAAAGGTACAAAGGCACCACAGGCAGCCGGCAAGATACATACTGATTTCGAGCGTGGCTTCATC
AAGGCGGAGGTAGTCAACTATCAGGATCTTCTTGACAACGGAAGCCTTGCAGCCGCAAGAGAAAAGGGCATCGTAGGCAT
GGAAGGAAAAGAGTACGTTGTTAAGGACGGAGATGTAATTCTTTTCAGATTTAATGTATAA

Upstream 100 bases:

>100_bases
TGTACAAATCTCTTGCAATGTGGTACACTACATAGTTGTATCAACAAACATCCGATACACAAAATACATATGAAATCAAT
TTAAAGGAGATATATATACC

Downstream 100 bases:

>100_bases
TTTTATGAATAAAACGCTTTTATAAGCACAAAATCAAAAAGAAACGCATAAGATAGACCAAGGGAGGTCTGTTTTATGCG
TTTTCTGGATTTATGCGAAA

Product: translation-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MKLGIVGLPNVGKSTLFNSLTKAGALSANYPFATIDPNVGIVSVPDERIVKLGELYHTKKVTPATIEFVDIAGLVKGASK
GEGLGNQFLANIREVDAIVHVVRCFEDTNIIHVDGSVDPARDIETINLELIFSDVEILDRRIAKIAKQARMDKTLAKELE
LVEAVKAHLEDGKMARTFEVPDDEDAQLWFKGYNLLTAKPTIYAANVSEDDLADDGASNPHVAKVREMAKEEGAEVFVIC
AQIEQELADLDEDEKKEYLEDLGVESSGLDKLVAASYSLLGLISFLTAGEDECRAWTIKKGTKAPQAAGKIHTDFERGFI
KAEVVNYQDLLDNGSLAAAREKGIVGMEGKEYVVKDGDVILFRFNV

Sequences:

>Translated_366_residues
MKLGIVGLPNVGKSTLFNSLTKAGALSANYPFATIDPNVGIVSVPDERIVKLGELYHTKKVTPATIEFVDIAGLVKGASK
GEGLGNQFLANIREVDAIVHVVRCFEDTNIIHVDGSVDPARDIETINLELIFSDVEILDRRIAKIAKQARMDKTLAKELE
LVEAVKAHLEDGKMARTFEVPDDEDAQLWFKGYNLLTAKPTIYAANVSEDDLADDGASNPHVAKVREMAKEEGAEVFVIC
AQIEQELADLDEDEKKEYLEDLGVESSGLDKLVAASYSLLGLISFLTAGEDECRAWTIKKGTKAPQAAGKIHTDFERGFI
KAEVVNYQDLLDNGSLAAAREKGIVGMEGKEYVVKDGDVILFRFNV
>Mature_366_residues
MKLGIVGLPNVGKSTLFNSLTKAGALSANYPFATIDPNVGIVSVPDERIVKLGELYHTKKVTPATIEFVDIAGLVKGASK
GEGLGNQFLANIREVDAIVHVVRCFEDTNIIHVDGSVDPARDIETINLELIFSDVEILDRRIAKIAKQARMDKTLAKELE
LVEAVKAHLEDGKMARTFEVPDDEDAQLWFKGYNLLTAKPTIYAANVSEDDLADDGASNPHVAKVREMAKEEGAEVFVIC
AQIEQELADLDEDEKKEYLEDLGVESSGLDKLVAASYSLLGLISFLTAGEDECRAWTIKKGTKAPQAAGKIHTDFERGFI
KAEVVNYQDLLDNGSLAAAREKGIVGMEGKEYVVKDGDVILFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=371, Percent_Identity=45.822102425876, Blast_Score=301, Evalue=5e-82,
Organism=Homo sapiens, GI58761502, Length=218, Percent_Identity=40.3669724770642, Blast_Score=154, Evalue=1e-37,
Organism=Escherichia coli, GI1787454, Length=367, Percent_Identity=51.4986376021798, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1789574, Length=152, Percent_Identity=27.6315789473684, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=369, Percent_Identity=44.1734417344173, Blast_Score=290, Evalue=7e-79,
Organism=Saccharomyces cerevisiae, GI6319499, Length=373, Percent_Identity=42.3592493297587, Blast_Score=263, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6321773, Length=383, Percent_Identity=37.3368146214099, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6321649, Length=330, Percent_Identity=29.3939393939394, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=44.9864498644986, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=44.9864498644986, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=44.9864498644986, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=43.5975609756098, Blast_Score=241, Evalue=7e-64,
Organism=Drosophila melanogaster, GI24585318, Length=157, Percent_Identity=29.2993630573248, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39955; Mature: 39955

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGIVGLPNVGKSTLFNSLTKAGALSANYPFATIDPNVGIVSVPDERIVKLGELYHTKK
CCEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHHHCC
VTPATIEFVDIAGLVKGASKGEGLGNQFLANIREVDAIVHVVRCFEDTNIIHVDGSVDPA
CCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
RDIETINLELIFSDVEILDRRIAKIAKQARMDKTLAKELELVEAVKAHLEDGKMARTFEV
CCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
PDDEDAQLWFKGYNLLTAKPTIYAANVSEDDLADDGASNPHVAKVREMAKEEGAEVFVIC
CCCCCCEEEEECCEEEEECCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEH
AQIEQELADLDEDEKKEYLEDLGVESSGLDKLVAASYSLLGLISFLTAGEDECRAWTIKK
HHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECC
GTKAPQAAGKIHTDFERGFIKAEVVNYQDLLDNGSLAAAREKGIVGMEGKEYVVKDGDVI
CCCCCHHCCCCCCHHHHCEEEEEEECHHHHHCCCCEEHHHHCCCCCCCCCEEEEECCCEE
LFRFNV
EEEECC
>Mature Secondary Structure
MKLGIVGLPNVGKSTLFNSLTKAGALSANYPFATIDPNVGIVSVPDERIVKLGELYHTKK
CCEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHHHCC
VTPATIEFVDIAGLVKGASKGEGLGNQFLANIREVDAIVHVVRCFEDTNIIHVDGSVDPA
CCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
RDIETINLELIFSDVEILDRRIAKIAKQARMDKTLAKELELVEAVKAHLEDGKMARTFEV
CCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
PDDEDAQLWFKGYNLLTAKPTIYAANVSEDDLADDGASNPHVAKVREMAKEEGAEVFVIC
CCCCCCEEEEECCEEEEECCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEH
AQIEQELADLDEDEKKEYLEDLGVESSGLDKLVAASYSLLGLISFLTAGEDECRAWTIKK
HHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECC
GTKAPQAAGKIHTDFERGFIKAEVVNYQDLLDNGSLAAAREKGIVGMEGKEYVVKDGDVI
CCCCCHHCCCCCCHHHHCEEEEEEECHHHHHCCCCEEHHHHCCCCCCCCCEEEEECCCEE
LFRFNV
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]