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The map label for this gene is yjmD [H]

Identifier: 238923788

GI number: 238923788

Start: 1291681

End: 1292709

Strand: Direct

Name: yjmD [H]

Synonym: EUBREC_1410

Alternate gene names: 238923788

Gene position: 1291681-1292709 (Clockwise)

Preceding gene: 238923786

Following gene: 238923789

Centisome position: 37.44

GC content: 40.43

Gene sequence:

>1029_bases
ATGTTACAGCAGGTAATGACAAATCCAGGAGAAATTATTTTCAGAGAGGTTCCGGTTCCGGAGGTAAAGGAAAACCAGGT
TTTGGTAAAGATTATGAATATTGGTGTTTGTGGATCAGATATTCATGTTTATCATGGAAAACATCCGTTTACAAAATATC
CGGTAACACAAGGACATGAGGTTTCAGGTGAGATTACAGAACTTGGAAAAAACGTCACAGAGTTTCATGTGGGACAAAAG
GTGACGATAGAGCCTCAGGTATATTGTGGACATTGCTATCCATGTCGTCATGGAAAGTATAATCTCTGTGAGGAATTAAA
AGTAATGGGATTTCAGACAACAGGAACAGCATCTGAGTATTTTGCAGTGGATGCATCTAAAGTAACACCTATTCCAAAAG
AAATGTCCTATGAAGAAGGAGCTATGATCGAACCTCTTGCTGTGGCAGTTCATGGTGTAAAACAGATGGGCGATGTGGCT
GGCATGAATATTGCAGTCCTTGGAGCAGGACCGATTGGAAATCTCGTGGCACAAACAGCAATTGGAATGGGTGCAGCGAA
AGTAATGATCACAGATATTAGTGATCTTAGACTGGCAAAGGCAAAAGAATGTGGAATTGATGTGTGTGTGAATACCAAAA
ATAAAGACTTCGGTGAGGCAATGATCGAAGCATTTGGACCGGATAAGGCAGATGTGATCTACGACTGTGCCGGAAACAAT
ATCACAATGGGACAGGCAATTAAATATGCAAGAAAAGGAAGCACGATTGTATTGGTGGCTGTTTTTGCAGGAATGGCAGA
AGTAGATCTTGCAGTGGCAAATGATCACGAACTTGACATTAAGAGCACGATGATGTACCGCCATGATGATTACATAGATG
GAATCAGACTGGTAAATGAGGGAAAAGTTCATTTGAAACCGCTCATCTCAAAGACATTTGCTTTTAAAGATTATCTGAAG
GCATACCAGTATATTGATGATAACCGCGAGACAACGATGAAAGTGATTATCAACGTCAGTGAAAAGTAA

Upstream 100 bases:

>100_bases
CATATTGACAAATTGTGTTTACAAGGTAATAATGTAATTACTTTAATAAAACAATTTATAAAACATAAAATAAAACAGCA
TAAAAAAGGAGGAAACAATT

Downstream 100 bases:

>100_bases
GGAGTTCGTATGGAAAATAAATATGGAATTGTCGGAGTAGCCCATGTCGGGCTCCCGACAAACGATTTACAGAAAACAGT
TGAGTTTTATAAGAGTCTTG

Product: hypothetical protein

Products: L-sorbose; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLQQVMTNPGEIIFREVPVPEVKENQVLVKIMNIGVCGSDIHVYHGKHPFTKYPVTQGHEVSGEITELGKNVTEFHVGQK
VTIEPQVYCGHCYPCRHGKYNLCEELKVMGFQTTGTASEYFAVDASKVTPIPKEMSYEEGAMIEPLAVAVHGVKQMGDVA
GMNIAVLGAGPIGNLVAQTAIGMGAAKVMITDISDLRLAKAKECGIDVCVNTKNKDFGEAMIEAFGPDKADVIYDCAGNN
ITMGQAIKYARKGSTIVLVAVFAGMAEVDLAVANDHELDIKSTMMYRHDDYIDGIRLVNEGKVHLKPLISKTFAFKDYLK
AYQYIDDNRETTMKVIINVSEK

Sequences:

>Translated_342_residues
MLQQVMTNPGEIIFREVPVPEVKENQVLVKIMNIGVCGSDIHVYHGKHPFTKYPVTQGHEVSGEITELGKNVTEFHVGQK
VTIEPQVYCGHCYPCRHGKYNLCEELKVMGFQTTGTASEYFAVDASKVTPIPKEMSYEEGAMIEPLAVAVHGVKQMGDVA
GMNIAVLGAGPIGNLVAQTAIGMGAAKVMITDISDLRLAKAKECGIDVCVNTKNKDFGEAMIEAFGPDKADVIYDCAGNN
ITMGQAIKYARKGSTIVLVAVFAGMAEVDLAVANDHELDIKSTMMYRHDDYIDGIRLVNEGKVHLKPLISKTFAFKDYLK
AYQYIDDNRETTMKVIINVSEK
>Mature_342_residues
MLQQVMTNPGEIIFREVPVPEVKENQVLVKIMNIGVCGSDIHVYHGKHPFTKYPVTQGHEVSGEITELGKNVTEFHVGQK
VTIEPQVYCGHCYPCRHGKYNLCEELKVMGFQTTGTASEYFAVDASKVTPIPKEMSYEEGAMIEPLAVAVHGVKQMGDVA
GMNIAVLGAGPIGNLVAQTAIGMGAAKVMITDISDLRLAKAKECGIDVCVNTKNKDFGEAMIEAFGPDKADVIYDCAGNN
ITMGQAIKYARKGSTIVLVAVFAGMAEVDLAVANDHELDIKSTMMYRHDDYIDGIRLVNEGKVHLKPLISKTFAFKDYLK
AYQYIDDNRETTMKVIINVSEK

Specific function: Not Known; Probable Catabolic Enzyme. [C]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=328, Percent_Identity=31.7073170731707, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI71565154, Length=268, Percent_Identity=28.3582089552239, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4501929, Length=222, Percent_Identity=29.2792792792793, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4501933, Length=222, Percent_Identity=29.7297297297297, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI4501939, Length=233, Percent_Identity=24.4635193133047, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI156523966, Length=233, Percent_Identity=24.4635193133047, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI71743840, Length=235, Percent_Identity=27.6595744680851, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI262073058, Length=235, Percent_Identity=27.6595744680851, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI34577061, Length=222, Percent_Identity=28.3783783783784, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI71565152, Length=363, Percent_Identity=23.4159779614325, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787863, Length=331, Percent_Identity=34.1389728096677, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI226510992, Length=335, Percent_Identity=30.7462686567164, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1788073, Length=349, Percent_Identity=31.2320916905444, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1790045, Length=314, Percent_Identity=28.9808917197452, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790718, Length=314, Percent_Identity=29.2993630573248, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788407, Length=328, Percent_Identity=30.1829268292683, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788075, Length=340, Percent_Identity=26.7647058823529, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI87082125, Length=251, Percent_Identity=32.2709163346614, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1786825, Length=379, Percent_Identity=24.5382585751979, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87081918, Length=294, Percent_Identity=27.2108843537415, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786552, Length=285, Percent_Identity=29.4736842105263, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082401, Length=133, Percent_Identity=30.8270676691729, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=329, Percent_Identity=35.8662613981763, Blast_Score=205, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17562878, Length=330, Percent_Identity=34.8484848484849, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI71988145, Length=340, Percent_Identity=26.1764705882353, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562582, Length=340, Percent_Identity=27.0588235294118, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI25146526, Length=282, Percent_Identity=29.0780141843972, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71997431, Length=283, Percent_Identity=28.6219081272085, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565904, Length=268, Percent_Identity=29.8507462686567, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562584, Length=338, Percent_Identity=24.2603550295858, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322619, Length=335, Percent_Identity=34.9253731343284, Blast_Score=195, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6319955, Length=335, Percent_Identity=34.9253731343284, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6323099, Length=349, Percent_Identity=32.9512893982808, Blast_Score=181, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6319258, Length=371, Percent_Identity=27.4932614555256, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319257, Length=356, Percent_Identity=25.2808988764045, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319621, Length=264, Percent_Identity=31.4393939393939, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323729, Length=261, Percent_Identity=29.5019157088123, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323961, Length=265, Percent_Identity=29.4339622641509, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324486, Length=265, Percent_Identity=28.6792452830189, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320033, Length=343, Percent_Identity=24.7813411078717, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17137530, Length=352, Percent_Identity=33.5227272727273, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI17737897, Length=357, Percent_Identity=33.3333333333333, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI45550770, Length=347, Percent_Identity=27.0893371757925, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI45551930, Length=347, Percent_Identity=27.0893371757925, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI221457811, Length=347, Percent_Identity=27.0893371757925, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17737895, Length=284, Percent_Identity=26.7605633802817, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.14

Molecular weight: Translated: 37472; Mature: 37472

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQQVMTNPGEIIFREVPVPEVKENQVLVKIMNIGVCGSDIHVYHGKHPFTKYPVTQGHE
CCCHHHCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCC
VSGEITELGKNVTEFHVGQKVTIEPQVYCGHCYPCRHGKYNLCEELKVMGFQTTGTASEY
CCCHHHHHCCCHHEEECCCEEEECCCEEECCEEECCCCCCCHHHHHHHEEEEECCCCCCE
FAVDASKVTPIPKEMSYEEGAMIEPLAVAVHGVKQMGDVAGMNIAVLGAGPIGNLVAQTA
EEEECHHCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHH
IGMGAAKVMITDISDLRLAKAKECGIDVCVNTKNKDFGEAMIEAFGPDKADVIYDCAGNN
HCCCEEEEEEECCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEEECCCC
ITMGQAIKYARKGSTIVLVAVFAGMAEVDLAVANDHELDIKSTMMYRHDDYIDGIRLVNE
EEHHHHHHHHHCCCEEEEEEECCCHHHEEEEEECCCCCCHHHHEEECCCCCCCCEEEECC
GKVHLKPLISKTFAFKDYLKAYQYIDDNRETTMKVIINVSEK
CCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MLQQVMTNPGEIIFREVPVPEVKENQVLVKIMNIGVCGSDIHVYHGKHPFTKYPVTQGHE
CCCHHHCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCC
VSGEITELGKNVTEFHVGQKVTIEPQVYCGHCYPCRHGKYNLCEELKVMGFQTTGTASEY
CCCHHHHHCCCHHEEECCCEEEECCCEEECCEEECCCCCCCHHHHHHHEEEEECCCCCCE
FAVDASKVTPIPKEMSYEEGAMIEPLAVAVHGVKQMGDVAGMNIAVLGAGPIGNLVAQTA
EEEECHHCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHH
IGMGAAKVMITDISDLRLAKAKECGIDVCVNTKNKDFGEAMIEAFGPDKADVIYDCAGNN
HCCCEEEEEEECCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEEECCCC
ITMGQAIKYARKGSTIVLVAVFAGMAEVDLAVANDHELDIKSTMMYRHDDYIDGIRLVNE
EEHHHHHHHHHCCCEEEEEEECCCHHHEEEEEECCCCCCHHHHEEECCCCCCCCEEEECC
GKVHLKPLISKTFAFKDYLKAYQYIDDNRETTMKVIINVSEK
CCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-iditol; NAD+

Specific reaction: L-iditol + NAD+ = L-sorbose + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]