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The map label for this gene is hsdS [H]

Identifier: 238923780

GI number: 238923780

Start: 1282656

End: 1283933

Strand: Direct

Name: hsdS [H]

Synonym: EUBREC_1402

Alternate gene names: 238923780

Gene position: 1282656-1283933 (Clockwise)

Preceding gene: 238923779

Following gene: 238923781

Centisome position: 37.18

GC content: 35.84

Gene sequence:

>1278_bases
ATGGGGAAGATGAGTAAATTATCAAACTTAATAACCCAGTATTGTCCAGAAGGTGTTGAATATAAGACTCTAGGAGAGTG
TGGAAAATTTTACGGTGGATTAACGGGAAAATCAAAAAAAGATTTTGAAGATGGTAATTCAAAGTTTATTACATATAAGA
ATGTATATTCTAATCCTGCGCTGTGCTTAGATGTAGAAGATAAGGTGAGAATTGAACCAGGCGAAAGACAACGAACACTA
GAATATGGAGATATTGTCTTTACGGGATCATCTGAAACTCCAGATGAATGCGGAATATCATCAGTTGTAGCAGAAATCCC
AGAAGAAAATTTATATCTGAATAGTTTCTGTTTCATTTTTAGATTTGATGATCCTTCTATATTGTTGCCAGATTTCGCAA
AACACCTATTTAGATCTTCAGAGTTGAGGTATCAAATAGGAAAGACGGCAAGCGGAGTGACCAGATATAATGTATCAAAA
AAACTAATGGGAAAAGTGAGCTTCCCTGTACCTCCTTTGGAGGTACAACGTGAAATAGTCCGCGTGTTGGACTCTTTCAC
GTTACTTACAGCCGAGCTTACAGCCGAGCTTACAGCTCGTAAACAGCAATATGAGTTCTATCGTGATTACCTATTAAATG
GAAACAGCGACTATGATATATGTAATTTGGGTGATGTTTGTGATGTGGTAGCAGGTGGAACACCTTCAAGAAAAGTGAGT
GACTATTGGGAAGATGGATGTATCCCGTGGCTAGGATCGACTGTCTGTAAAAATAAAAAAAATGTTGATGAGCCTACAGA
ATTTATAACGGAATTAGGTCTAGAAAAATCATCAGCCAAGATGATGAAAAAAGACACAACGCTTATCGCATTGGTTGGCG
CAACTATAGGAAAAGTTGCATTTACAACATTTGACGTAGCTATCAATCAAAACATTGCTGGGGTATATCCTAAAGATACA
AGTAAAATTAATCCGTCATATATATATTATGCTTGTACAACGTTATATCCACATTTTTTAAATTTAACGCAAGGGTCAAA
ACTTGCAATGGCAAATTTGACATTTGTTAGAGGTTTAAAAATATCTGTACCACCAATTGATGTGCAGAACCACCTAGTGA
ATGTACTCGATAATTTTGAATCGATAACATCCGATTTAAGTATTGGATTACCAGCAGAAATAGAGGCAAGAAAAAAACAA
TATGAATACTACAGGGATGCTTTATTGACATATGCTTCTACTGGAAAGATAATTGCTAGACAGACAGAACATAATTAG

Upstream 100 bases:

>100_bases
ACTGCAGCAAATTTTGTGACAGGAAATAGTACAAACGGTTTAATAGCATGGAAAAATAAAGATGGAGTAATATTGAAGAC
TCTCATTTCTGGAAAGGAGG

Downstream 100 bases:

>100_bases
ACTTGTTCAATAATGTGTTCGGATATGCAAAATTAGAACTTGGAGAAGTATGTAGTTCGATTTCTTCAGGTAAATCAAAG
GAAAGGTCAAAAACAGGACC

Product: putative type I restriction enzyme (specificity subunit)

Products: NA

Alternate protein names: S.EcoR124II; Type I restriction enzyme EcoR124II specificity protein; S protein [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MGKMSKLSNLITQYCPEGVEYKTLGECGKFYGGLTGKSKKDFEDGNSKFITYKNVYSNPALCLDVEDKVRIEPGERQRTL
EYGDIVFTGSSETPDECGISSVVAEIPEENLYLNSFCFIFRFDDPSILLPDFAKHLFRSSELRYQIGKTASGVTRYNVSK
KLMGKVSFPVPPLEVQREIVRVLDSFTLLTAELTAELTARKQQYEFYRDYLLNGNSDYDICNLGDVCDVVAGGTPSRKVS
DYWEDGCIPWLGSTVCKNKKNVDEPTEFITELGLEKSSAKMMKKDTTLIALVGATIGKVAFTTFDVAINQNIAGVYPKDT
SKINPSYIYYACTTLYPHFLNLTQGSKLAMANLTFVRGLKISVPPIDVQNHLVNVLDNFESITSDLSIGLPAEIEARKKQ
YEYYRDALLTYASTGKIIARQTEHN

Sequences:

>Translated_425_residues
MGKMSKLSNLITQYCPEGVEYKTLGECGKFYGGLTGKSKKDFEDGNSKFITYKNVYSNPALCLDVEDKVRIEPGERQRTL
EYGDIVFTGSSETPDECGISSVVAEIPEENLYLNSFCFIFRFDDPSILLPDFAKHLFRSSELRYQIGKTASGVTRYNVSK
KLMGKVSFPVPPLEVQREIVRVLDSFTLLTAELTAELTARKQQYEFYRDYLLNGNSDYDICNLGDVCDVVAGGTPSRKVS
DYWEDGCIPWLGSTVCKNKKNVDEPTEFITELGLEKSSAKMMKKDTTLIALVGATIGKVAFTTFDVAINQNIAGVYPKDT
SKINPSYIYYACTTLYPHFLNLTQGSKLAMANLTFVRGLKISVPPIDVQNHLVNVLDNFESITSDLSIGLPAEIEARKKQ
YEYYRDALLTYASTGKIIARQTEHN
>Mature_424_residues
GKMSKLSNLITQYCPEGVEYKTLGECGKFYGGLTGKSKKDFEDGNSKFITYKNVYSNPALCLDVEDKVRIEPGERQRTLE
YGDIVFTGSSETPDECGISSVVAEIPEENLYLNSFCFIFRFDDPSILLPDFAKHLFRSSELRYQIGKTASGVTRYNVSKK
LMGKVSFPVPPLEVQREIVRVLDSFTLLTAELTAELTARKQQYEFYRDYLLNGNSDYDICNLGDVCDVVAGGTPSRKVSD
YWEDGCIPWLGSTVCKNKKNVDEPTEFITELGLEKSSAKMMKKDTTLIALVGATIGKVAFTTFDVAINQNIAGVYPKDTS
KINPSYIYYACTTLYPHFLNLTQGSKLAMANLTFVRGLKISVPPIDVQNHLVNVLDNFESITSDLSIGLPAEIEARKKQY
EYYRDALLTYASTGKIIARQTEHN

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 47576; Mature: 47444

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKMSKLSNLITQYCPEGVEYKTLGECGKFYGGLTGKSKKDFEDGNSKFITYKNVYSNPA
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCE
LCLDVEDKVRIEPGERQRTLEYGDIVFTGSSETPDECGISSVVAEIPEENLYLNSFCFIF
EEEECCCCEEECCCCCCCEEEECCEEEECCCCCCHHCCHHHHHHHCCCCCEEEEEEEEEE
RFDDPSILLPDFAKHLFRSSELRYQIGKTASGVTRYNVSKKLMGKVSFPVPPLEVQREIV
EECCCCEEHHHHHHHHHCCCCCEEECCCCCCCCEEECHHHHHHCCCCCCCCCHHHHHHHH
RVLDSFTLLTAELTAELTARKQQYEFYRDYLLNGNSDYDICNLGDVCDVVAGGTPSRKVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHCCCCCCCCHH
DYWEDGCIPWLGSTVCKNKKNVDEPTEFITELGLEKSSAKMMKKDTTLIALVGATIGKVA
HHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEEHHHHHHHH
FTTFDVAINQNIAGVYPKDTSKINPSYIYYACTTLYPHFLNLTQGSKLAMANLTFVRGLK
HEEEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCEEEEEEEHHHCCEE
ISVPPIDVQNHLVNVLDNFESITSDLSIGLPAEIEARKKQYEYYRDALLTYASTGKIIAR
EECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEE
QTEHN
CCCCC
>Mature Secondary Structure 
GKMSKLSNLITQYCPEGVEYKTLGECGKFYGGLTGKSKKDFEDGNSKFITYKNVYSNPA
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCE
LCLDVEDKVRIEPGERQRTLEYGDIVFTGSSETPDECGISSVVAEIPEENLYLNSFCFIF
EEEECCCCEEECCCCCCCEEEECCEEEECCCCCCHHCCHHHHHHHCCCCCEEEEEEEEEE
RFDDPSILLPDFAKHLFRSSELRYQIGKTASGVTRYNVSKKLMGKVSFPVPPLEVQREIV
EECCCCEEHHHHHHHHHCCCCCEEECCCCCCCCEEECHHHHHHCCCCCCCCCHHHHHHHH
RVLDSFTLLTAELTAELTARKQQYEFYRDYLLNGNSDYDICNLGDVCDVVAGGTPSRKVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHCCCCCCCCHH
DYWEDGCIPWLGSTVCKNKKNVDEPTEFITELGLEKSSAKMMKKDTTLIALVGATIGKVA
HHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEEHHHHHHHH
FTTFDVAINQNIAGVYPKDTSKINPSYIYYACTTLYPHFLNLTQGSKLAMANLTFVRGLK
HEEEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCEEEEEEEHHHCCEE
ISVPPIDVQNHLVNVLDNFESITSDLSIGLPAEIEARKKQYEYYRDALLTYASTGKIIAR
EECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEE
QTEHN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2784505 [H]