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The map label for this gene is hslO

Identifier: 238923735

GI number: 238923735

Start: 1228832

End: 1229698

Strand: Direct

Name: hslO

Synonym: EUBREC_1357

Alternate gene names: 238923735

Gene position: 1228832-1229698 (Clockwise)

Preceding gene: 238923734

Following gene: 238923736

Centisome position: 35.62

GC content: 48.33

Gene sequence:

>867_bases
ATGTCAGATTATATAGTAAGAGCAACAGCGGCGGATGCCAATATCAGAGCATTTGCTGTAACATCAAAGGAGATGGTGGA
GAACGCCAGAGAGGATCACATGACAACACCTGTCATGACGGCGGCACTTGGCAGACTCCTTTCTGCGGGAGCCATGATGG
GAGCTATGATGAAGGGCGATAAGGATATCATAACTCTTCAGATACAGTGCAGCGGACCTGCAAAGGGACTTACCGTCACA
GCAGATTCGCACGGCAATGTAAAGGGCTTTGCCATGAATCCACAGGTTGAGCTGCCACTCAATGCGGCAGGCAAGCTCGA
TGTGGGAGGAGCGCTTGATCTTGGTATACTTACAGTCATAAAGGATATGGGCTTAAAGGAGCCGTATTCAGGTCAGTGTG
AGCTTAAAACAGGTGAGATAGCTGAGGATCTGACTTATTATTTTGCCACATCTGAGCAGATTCCGTCGGCGGTTGGTCTT
GGCGTGCTGGTGGATAAGGACCAGAGCGTGAAGCAGTCCGGTGGATTTATCATCCAGCTTATGCCGTTTACACCGGAGGA
TGTTGTGGACAGGCTTGAAAAGAAAATCACAGAGATTGATTCTGTGACACAGATGCTTGACAGGGGGCTGACTCCGGAGC
AGATACTTGAGGAAATTTTAGGGGATTTCGGGCTTGAAATCACAGATACGACAGAGACACGCTTCCACTGTGACTGTTCA
AAGGAGCGTGTGAGCAGAGCACTTTCCACACTTAGCAAAAAGGATCTTGATTCCATTATCGCAGATGGCGAGAGCATTGA
GGTAAAGTGCCAGTTCTGTAATAAGGCATATGAGTTTACGGTGGATGAGTTGAAGGAGATGCGCTAA

Upstream 100 bases:

>100_bases
CGGTGTATGATGCGTACACAGACAATCAGGTGAAATGTGACAGTGAGAAGGTCACTTTAATTGCACATAAAGCATAGAAT
TAGATAATGAGAGGTAAATT

Downstream 100 bases:

>100_bases
TTGAAGGACGGATATATAAAGGTCGCTGCAGCGACACCAAAGGTAAAGGTAGCTGATACTGTATACAACGGACAGCTTAT
TAAAGCTCTTATGAAGGAGT

Product: chaperonin, 33 kDa

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSDYIVRATAADANIRAFAVTSKEMVENAREDHMTTPVMTAALGRLLSAGAMMGAMMKGDKDIITLQIQCSGPAKGLTVT
ADSHGNVKGFAMNPQVELPLNAAGKLDVGGALDLGILTVIKDMGLKEPYSGQCELKTGEIAEDLTYYFATSEQIPSAVGL
GVLVDKDQSVKQSGGFIIQLMPFTPEDVVDRLEKKITEIDSVTQMLDRGLTPEQILEEILGDFGLEITDTTETRFHCDCS
KERVSRALSTLSKKDLDSIIADGESIEVKCQFCNKAYEFTVDELKEMR

Sequences:

>Translated_288_residues
MSDYIVRATAADANIRAFAVTSKEMVENAREDHMTTPVMTAALGRLLSAGAMMGAMMKGDKDIITLQIQCSGPAKGLTVT
ADSHGNVKGFAMNPQVELPLNAAGKLDVGGALDLGILTVIKDMGLKEPYSGQCELKTGEIAEDLTYYFATSEQIPSAVGL
GVLVDKDQSVKQSGGFIIQLMPFTPEDVVDRLEKKITEIDSVTQMLDRGLTPEQILEEILGDFGLEITDTTETRFHCDCS
KERVSRALSTLSKKDLDSIIADGESIEVKCQFCNKAYEFTVDELKEMR
>Mature_287_residues
SDYIVRATAADANIRAFAVTSKEMVENAREDHMTTPVMTAALGRLLSAGAMMGAMMKGDKDIITLQIQCSGPAKGLTVTA
DSHGNVKGFAMNPQVELPLNAAGKLDVGGALDLGILTVIKDMGLKEPYSGQCELKTGEIAEDLTYYFATSEQIPSAVGLG
VLVDKDQSVKQSGGFIIQLMPFTPEDVVDRLEKKITEIDSVTQMLDRGLTPEQILEEILGDFGLEITDTTETRFHCDCSK
ERVSRALSTLSKKDLDSIIADGESIEVKCQFCNKAYEFTVDELKEMR

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=289, Percent_Identity=28.3737024221453, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_EUBR3 (C4Z899)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002937251.1
- ProteinModelPortal:   C4Z899
- GeneID:   7966211
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_1357
- ProtClustDB:   CLSK2506408
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 31288; Mature: 31157

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYIVRATAADANIRAFAVTSKEMVENAREDHMTTPVMTAALGRLLSAGAMMGAMMKGD
CCCEEEEEECCCCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
KDIITLQIQCSGPAKGLTVTADSHGNVKGFAMNPQVELPLNAAGKLDVGGALDLGILTVI
CEEEEEEEEECCCCCCEEEEECCCCCEEEEEECCEEEECCCCCCCCCCCCCHHHHHHHHH
KDMGLKEPYSGQCELKTGEIAEDLTYYFATSEQIPSAVGLGVLVDKDQSVKQSGGFIIQL
HHCCCCCCCCCEEEEECCCHHHHHHHEEECCHHCCHHHCCCEEECCCCHHHHCCCEEEEE
MPFTPEDVVDRLEKKITEIDSVTQMLDRGLTPEQILEEILGDFGLEITDTTETRFHCDCS
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEECCCCCEEECCCC
KERVSRALSTLSKKDLDSIIADGESIEVKCQFCNKAYEFTVDELKEMR
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHCCHHHHHCCC
>Mature Secondary Structure 
SDYIVRATAADANIRAFAVTSKEMVENAREDHMTTPVMTAALGRLLSAGAMMGAMMKGD
CCEEEEEECCCCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
KDIITLQIQCSGPAKGLTVTADSHGNVKGFAMNPQVELPLNAAGKLDVGGALDLGILTVI
CEEEEEEEEECCCCCCEEEEECCCCCEEEEEECCEEEECCCCCCCCCCCCCHHHHHHHHH
KDMGLKEPYSGQCELKTGEIAEDLTYYFATSEQIPSAVGLGVLVDKDQSVKQSGGFIIQL
HHCCCCCCCCCEEEEECCCHHHHHHHEEECCHHCCHHHCCCEEECCCCHHHHCCCEEEEE
MPFTPEDVVDRLEKKITEIDSVTQMLDRGLTPEQILEEILGDFGLEITDTTETRFHCDCS
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEECCCCCEEECCCC
KERVSRALSTLSKKDLDSIIADGESIEVKCQFCNKAYEFTVDELKEMR
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA