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The map label for this gene is malE [H]

Identifier: 238923563

GI number: 238923563

Start: 1094889

End: 1096151

Strand: Direct

Name: malE [H]

Synonym: EUBREC_1183

Alternate gene names: 238923563

Gene position: 1094889-1096151 (Clockwise)

Preceding gene: 238923559

Following gene: 238923564

Centisome position: 31.74

GC content: 42.76

Gene sequence:

>1263_bases
ATGAAGAAAAGGGTGTTGAGTTTGTTGCTCTGTACCGCAATGACAATCGGCACATTATCCGGTTGTGGAAAAGAAGCAGG
AAATGACGAAGGAAAGGCTACAGAAGCACTTGGAAATGATGCAGAGGATGAAATGACAGAGGTAAAAATCTGGCATGATG
GGGATGAGAATATCATGCAGACCATTGCGGATTGTGCGAATGAGAAACTGGCAGAGGATAATATCAAGGTTACCTTTGAA
AAGAAGAGCGGTCTGACCGACCAGCTTCAGTTATATGGAAATGATGAATCCAACGGACCGGATATGTATCTTTATGCACA
TGATTCATTGGGAACATTTGCAGAAATGGGGATTTTAGCTCCGATTACGGATGTTATCAGTGAGGATGTAATGGCGGATT
TATTACCGATGACCGTAGAAGCAGGTAATTATAAGGATACCCAGTACCTGATGCCGGTTTATTATGAGACATTGCTCTTT
ATGTATAATAAGGCAAAATGGGAAGGTGATGTGCCGGAAACAACAGATGAACTGTATGATTATATGGTAGCGCATACCGA
TGTGAATGCAGGAACTTATGCGCTGGTAAATCAGCATTCTACCGCATACAATGTGGCACCGGTGATCAATGGTTTTGGTG
GATATATTATTGATAAAGATGCAAATCCTGGATTAAATACACAGGAAACCAAGGATGCTATCGCATACAATAAGAAATTT
GCAGCATTGGAGGCAGACGGAGATTACAACACAGTAACTGCATTATTCAATGAAGGCCAGGCAGCAGCAATCATCGGTGG
ACCATGGCTGGTATCCGGAATCAAGGCAGCGGGCATTGATCTTGGTATTAAATCTTTAGCGGATTTTAAACTTCCGAATG
GAAACGGACTGGCACCATATTCAGGTGTACAGAGCATTGGTGTCTTAAAATATGCAGCAGAAAATAAGAAAGAAGCAATT
GCAAAAGTATTAGAGACAATTGCAAGTCCGGAAGTAGGTATTGCACTGGCGAATAAATCAAACTGTGCACCGGCAAACAG
CAAAGCATATGATGACGCAGATGTTGCTGCAAATGAGATGATTATGGCAATGAAAGCAACTGCAGAAACTGCACAGCCTA
TGCCAAACATTCCGCAGATGAGCGTTATGTGGGGTCCGGCAGAAGCATTTTTGGCGGCAGTCAACAAATCCGGGGAGGAT
ATTGATACTGCAGCAGAAACTTATCAGCAGGAGGCATTGGATGCTATTGCAGATATGCAGTAA

Upstream 100 bases:

>100_bases
TTTATTTGCAAACCTTCAATAAATCAAGGTTTTAAAAGAATTTTAGAACAATAAAATGGGTAGTTTTTGACACTACCAAC
CGGAAAACGGAGGTATTTTT

Downstream 100 bases:

>100_bases
GAAGGAGTTTATTTAGAAGCAATATAAAGAGGAAAATTAGGAAGAGAAGTGTGTATATGAAGAACAAACGGAAATTAACG
CCATGGCTTTACAGTATGCC

Product: ABC-type maltodextrin transport system, maltodextrin-binding periplasmic component

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: MMBP; Maltodextrin-binding protein [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MKKRVLSLLLCTAMTIGTLSGCGKEAGNDEGKATEALGNDAEDEMTEVKIWHDGDENIMQTIADCANEKLAEDNIKVTFE
KKSGLTDQLQLYGNDESNGPDMYLYAHDSLGTFAEMGILAPITDVISEDVMADLLPMTVEAGNYKDTQYLMPVYYETLLF
MYNKAKWEGDVPETTDELYDYMVAHTDVNAGTYALVNQHSTAYNVAPVINGFGGYIIDKDANPGLNTQETKDAIAYNKKF
AALEADGDYNTVTALFNEGQAAAIIGGPWLVSGIKAAGIDLGIKSLADFKLPNGNGLAPYSGVQSIGVLKYAAENKKEAI
AKVLETIASPEVGIALANKSNCAPANSKAYDDADVAANEMIMAMKATAETAQPMPNIPQMSVMWGPAEAFLAAVNKSGED
IDTAAETYQQEALDAIADMQ

Sequences:

>Translated_420_residues
MKKRVLSLLLCTAMTIGTLSGCGKEAGNDEGKATEALGNDAEDEMTEVKIWHDGDENIMQTIADCANEKLAEDNIKVTFE
KKSGLTDQLQLYGNDESNGPDMYLYAHDSLGTFAEMGILAPITDVISEDVMADLLPMTVEAGNYKDTQYLMPVYYETLLF
MYNKAKWEGDVPETTDELYDYMVAHTDVNAGTYALVNQHSTAYNVAPVINGFGGYIIDKDANPGLNTQETKDAIAYNKKF
AALEADGDYNTVTALFNEGQAAAIIGGPWLVSGIKAAGIDLGIKSLADFKLPNGNGLAPYSGVQSIGVLKYAAENKKEAI
AKVLETIASPEVGIALANKSNCAPANSKAYDDADVAANEMIMAMKATAETAQPMPNIPQMSVMWGPAEAFLAAVNKSGED
IDTAAETYQQEALDAIADMQ
>Mature_420_residues
MKKRVLSLLLCTAMTIGTLSGCGKEAGNDEGKATEALGNDAEDEMTEVKIWHDGDENIMQTIADCANEKLAEDNIKVTFE
KKSGLTDQLQLYGNDESNGPDMYLYAHDSLGTFAEMGILAPITDVISEDVMADLLPMTVEAGNYKDTQYLMPVYYETLLF
MYNKAKWEGDVPETTDELYDYMVAHTDVNAGTYALVNQHSTAYNVAPVINGFGGYIIDKDANPGLNTQETKDAIAYNKKF
AALEADGDYNTVTALFNEGQAAAIIGGPWLVSGIKAAGIDLGIKSLADFKLPNGNGLAPYSGVQSIGVLKYAAENKKEAI
AKVLETIASPEVGIALANKSNCAPANSKAYDDADVAANEMIMAMKATAETAQPMPNIPQMSVMWGPAEAFLAAVNKSGED
IDTAAETYQQEALDAIADMQ

Specific function: Involved in an abc transport system for maltotriose [H]

COG id: COG2182

COG function: function code G; Maltose-binding periplasmic proteins/domains

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790466, Length=365, Percent_Identity=29.3150684931507, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006060
- InterPro:   IPR006059
- InterPro:   IPR006061 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 45025; Mature: 45025

Theoretical pI: Translated: 4.00; Mature: 4.00

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRVLSLLLCTAMTIGTLSGCGKEAGNDEGKATEALGNDAEDEMTEVKIWHDGDENIMQ
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCHHHHH
TIADCANEKLAEDNIKVTFEKKSGLTDQLQLYGNDESNGPDMYLYAHDSLGTFAEMGILA
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHH
PITDVISEDVMADLLPMTVEAGNYKDTQYLMPVYYETLLFMYNKAKWEGDVPETTDELYD
HHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
YMVAHTDVNAGTYALVNQHSTAYNVAPVINGFGGYIIDKDANPGLNTQETKDAIAYNKKF
HHHHCCCCCCCEEEEEECCCCCEEHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHCCEE
AALEADGDYNTVTALFNEGQAAAIIGGPWLVSGIKAAGIDLGIKSLADFKLPNGNGLAPY
EEEECCCCCCEEEEEECCCCEEEEECCHHHHHCHHHCCHHHHHHHHHHCCCCCCCCCCCC
SGVQSIGVLKYAAENKKEAIAKVLETIASPEVGIALANKSNCAPANSKAYDDADVAANEM
CCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
IMAMKATAETAQPMPNIPQMSVMWGPAEAFLAAVNKSGEDIDTAAETYQQEALDAIADMQ
HHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKRVLSLLLCTAMTIGTLSGCGKEAGNDEGKATEALGNDAEDEMTEVKIWHDGDENIMQ
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCHHHHH
TIADCANEKLAEDNIKVTFEKKSGLTDQLQLYGNDESNGPDMYLYAHDSLGTFAEMGILA
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHH
PITDVISEDVMADLLPMTVEAGNYKDTQYLMPVYYETLLFMYNKAKWEGDVPETTDELYD
HHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
YMVAHTDVNAGTYALVNQHSTAYNVAPVINGFGGYIIDKDANPGLNTQETKDAIAYNKKF
HHHHCCCCCCCEEEEEECCCCCEEHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHCCEE
AALEADGDYNTVTALFNEGQAAAIIGGPWLVSGIKAAGIDLGIKSLADFKLPNGNGLAPY
EEEECCCCCCEEEEEECCCCEEEEECCHHHHHCHHHCCHHHHHHHHHHCCCCCCCCCCCC
SGVQSIGVLKYAAENKKEAIAKVLETIASPEVGIALANKSNCAPANSKAYDDADVAANEM
CCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
IMAMKATAETAQPMPNIPQMSVMWGPAEAFLAAVNKSGEDIDTAAETYQQEALDAIADMQ
HHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]