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The map label for this gene is yfkJ [H]

Identifier: 238923540

GI number: 238923540

Start: 1067233

End: 1067676

Strand: Direct

Name: yfkJ [H]

Synonym: EUBREC_1160

Alternate gene names: 238923540

Gene position: 1067233-1067676 (Clockwise)

Preceding gene: 238923539

Following gene: 238923541

Centisome position: 30.94

GC content: 45.72

Gene sequence:

>444_bases
ATGGCCCAAAGCATCTTCACCCATCTGGTCCACAGACAGCACCTCGATGCTGTTTTCGAGATAGATTCAGCTGCGACCAG
CCGTGAGGAAATAGGCAATCCGCCGCACTACGGCACCAAAAACAAACTATACGAGGAGCATATTCCTCTTATTCCACACC
GCGCGAGACAGATGACACGCGATGATTATTTGTACTACGACCTTCTGATTGGAATGGACACTGCAAATATCAGGAATATG
ACAAGGATTGCAGGTGGCAGTGACAGTCAGCAGAAGATATTTAAGATGCTGTCATTTGCTGATTACGGGACAAATCATAA
GCTTACAGCAGCGCGCGATGTTGCAGATCCATGGTATACAGGTGATTTTGATGCGACCTTTGATGATGTAATCAGTGGAT
GCCGGGGCTTGTTAGAATACATAAAAGAGGTGTATAATCTATAG

Upstream 100 bases:

>100_bases
TAAAACCTTGCAAAACTCGGCATTATAGGGCATTTCAGAACAGGAGAATTTTATGATAAAAGTACTTTTCATCTGCTTAG
GCAACATCTGCCGCAGCACC

Downstream 100 bases:

>100_bases
CTATAGCAATTAAAAGAGAATAATAGCAGCGGTTACGGTGCTGAACACAGCTGCGATAATTAATTTCAGGAGGCACAAAT
GCAATTACAGAATGGAAGAC

Product: protein-tyrosine-phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MAQSIFTHLVHRQHLDAVFEIDSAATSREEIGNPPHYGTKNKLYEEHIPLIPHRARQMTRDDYLYYDLLIGMDTANIRNM
TRIAGGSDSQQKIFKMLSFADYGTNHKLTAARDVADPWYTGDFDATFDDVISGCRGLLEYIKEVYNL

Sequences:

>Translated_147_residues
MAQSIFTHLVHRQHLDAVFEIDSAATSREEIGNPPHYGTKNKLYEEHIPLIPHRARQMTRDDYLYYDLLIGMDTANIRNM
TRIAGGSDSQQKIFKMLSFADYGTNHKLTAARDVADPWYTGDFDATFDDVISGCRGLLEYIKEVYNL
>Mature_146_residues
AQSIFTHLVHRQHLDAVFEIDSAATSREEIGNPPHYGTKNKLYEEHIPLIPHRARQMTRDDYLYYDLLIGMDTANIRNMT
RIAGGSDSQQKIFKMLSFADYGTNHKLTAARDVADPWYTGDFDATFDDVISGCRGLLEYIKEVYNL

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=141, Percent_Identity=31.2056737588652, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6325330, Length=134, Percent_Identity=33.5820895522388, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16861; Mature: 16730

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSIFTHLVHRQHLDAVFEIDSAATSREEIGNPPHYGTKNKLYEEHIPLIPHRARQMTR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHHHCCC
DDYLYYDLLIGMDTANIRNMTRIAGGSDSQQKIFKMLSFADYGTNHKLTAARDVADPWYT
CHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
GDFDATFDDVISGCRGLLEYIKEVYNL
CCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQSIFTHLVHRQHLDAVFEIDSAATSREEIGNPPHYGTKNKLYEEHIPLIPHRARQMTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHHHCCC
DDYLYYDLLIGMDTANIRNMTRIAGGSDSQQKIFKMLSFADYGTNHKLTAARDVADPWYT
CHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
GDFDATFDDVISGCRGLLEYIKEVYNL
CCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]