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The map label for this gene is prpC [H]

Identifier: 238923493

GI number: 238923493

Start: 1020834

End: 1021610

Strand: Direct

Name: prpC [H]

Synonym: EUBREC_1113

Alternate gene names: 238923493

Gene position: 1020834-1021610 (Clockwise)

Preceding gene: 238923492

Following gene: 238923494

Centisome position: 29.59

GC content: 42.08

Gene sequence:

>777_bases
ATGGATTACGAAATTGCAGCCCAGACAGATGTGGGAACAGTCAAGAAAACAAATCAGGACAGCATAATGATGAAACGTAT
TTTTACCAATCTTGGGAATATGGTTTTTGCAGTATTGTGTGATGGTATGGGAGGTCTTGCGAAGGGTGAGCTTGCCAGTG
CTACGGTCATAAGAGCATTTGATAAGTGGGTCAACGATGATCTGCAGATGATTTGTCAGAATGGACCCGGATATATTGAG
GATTCTGTAATCAGGGCACAGTGGGAGAGTATAGTAGCAAATCAGAATCAAAAAATCAAACAGTATGGAGCAGGTCAGGG
CGTTAATCTTGGAACCACTGTAGTAGCGCTTCTTGTTACTGACAGGAGATACTATCTGATGAATGTCGGTGATTCAAGAG
CATATCTTGTAAATGATAAGCTCATACAGCTTACTAAGGATCAGACATTTGTAGGTAGAGAGATAGAGCTGGGTCATATG
ACAATAGAGCAGGCTAAAACAGACCCGCGCAGAAATGTGCTTTTACAGTGTGTGGGTGCTTCTGAGATTGTTAATCCTGA
CATGTTTTTTGGAGATGTGCAAAGTGGTACGGAGTTTCTGCTTTGTTCGGATGGTTTCAGACATGAGATTACATCTGATG
AGATTTATCAGGCAATCAGACCATCATTTATGACAAACAGGGATGTGATGAATAGGCAGCTTCGTTCTTTGATAGAACTC
AACATGCAGCGTAGGGAGAGAGACAATATCACAGCAGCGCTGATTAAGGTACAGTAG

Upstream 100 bases:

>100_bases
GCATGGAACGAAAATCAGACTGGCGAATGAGGATTTTGAATTTTTCATGTACTAATAAAAAAAATCACAGGATAAATATT
ACATATATTGAGGAAATGGC

Downstream 100 bases:

>100_bases
GAGGAAAGTTTATGCTTGAGATTGGTTCTCTTGTTGATGGAAAATACAAGATACTGAATGAAGTGGGCCATGGTGGGATG
AGTATCGTTTACCTGGCTAT

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MDYEIAAQTDVGTVKKTNQDSIMMKRIFTNLGNMVFAVLCDGMGGLAKGELASATVIRAFDKWVNDDLQMICQNGPGYIE
DSVIRAQWESIVANQNQKIKQYGAGQGVNLGTTVVALLVTDRRYYLMNVGDSRAYLVNDKLIQLTKDQTFVGREIELGHM
TIEQAKTDPRRNVLLQCVGASEIVNPDMFFGDVQSGTEFLLCSDGFRHEITSDEIYQAIRPSFMTNRDVMNRQLRSLIEL
NMQRRERDNITAALIKVQ

Sequences:

>Translated_258_residues
MDYEIAAQTDVGTVKKTNQDSIMMKRIFTNLGNMVFAVLCDGMGGLAKGELASATVIRAFDKWVNDDLQMICQNGPGYIE
DSVIRAQWESIVANQNQKIKQYGAGQGVNLGTTVVALLVTDRRYYLMNVGDSRAYLVNDKLIQLTKDQTFVGREIELGHM
TIEQAKTDPRRNVLLQCVGASEIVNPDMFFGDVQSGTEFLLCSDGFRHEITSDEIYQAIRPSFMTNRDVMNRQLRSLIEL
NMQRRERDNITAALIKVQ
>Mature_258_residues
MDYEIAAQTDVGTVKKTNQDSIMMKRIFTNLGNMVFAVLCDGMGGLAKGELASATVIRAFDKWVNDDLQMICQNGPGYIE
DSVIRAQWESIVANQNQKIKQYGAGQGVNLGTTVVALLVTDRRYYLMNVGDSRAYLVNDKLIQLTKDQTFVGREIELGHM
TIEQAKTDPRRNVLLQCVGASEIVNPDMFFGDVQSGTEFLLCSDGFRHEITSDEIYQAIRPSFMTNRDVMNRQLRSLIEL
NMQRRERDNITAALIKVQ

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 29046; Mature: 29046

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYEIAAQTDVGTVKKTNQDSIMMKRIFTNLGNMVFAVLCDGMGGLAKGELASATVIRAF
CCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
DKWVNDDLQMICQNGPGYIEDSVIRAQWESIVANQNQKIKQYGAGQGVNLGTTVVALLVT
HHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHEE
DRRYYLMNVGDSRAYLVNDKLIQLTKDQTFVGREIELGHMTIEQAKTDPRRNVLLQCVGA
CCEEEEEEECCCCEEEECCCEEEEECCCEECCCEEEECCEEHHHHCCCCCHHHHEEECCC
SEIVNPDMFFGDVQSGTEFLLCSDGFRHEITSDEIYQAIRPSFMTNRDVMNRQLRSLIEL
HHHCCCCCEECCCCCCCEEEEECCCCCCCCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHH
NMQRRERDNITAALIKVQ
HHHHHHHCCEEEEEEEEC
>Mature Secondary Structure
MDYEIAAQTDVGTVKKTNQDSIMMKRIFTNLGNMVFAVLCDGMGGLAKGELASATVIRAF
CCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
DKWVNDDLQMICQNGPGYIEDSVIRAQWESIVANQNQKIKQYGAGQGVNLGTTVVALLVT
HHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHEE
DRRYYLMNVGDSRAYLVNDKLIQLTKDQTFVGREIELGHMTIEQAKTDPRRNVLLQCVGA
CCEEEEEEECCCCEEEECCCEEEEECCCEECCCEEEECCEEHHHHCCCCCHHHHEEECCC
SEIVNPDMFFGDVQSGTEFLLCSDGFRHEITSDEIYQAIRPSFMTNRDVMNRQLRSLIEL
HHHCCCCCEECCCCCCCEEEEECCCCCCCCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHH
NMQRRERDNITAALIKVQ
HHHHHHHCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]