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The map label for this gene is malZ [C]

Identifier: 238923394

GI number: 238923394

Start: 912988

End: 914292

Strand: Direct

Name: malZ [C]

Synonym: EUBREC_1014

Alternate gene names: 238923394

Gene position: 912988-914292 (Clockwise)

Preceding gene: 238923393

Following gene: 238923395

Centisome position: 26.47

GC content: 45.29

Gene sequence:

>1305_bases
ATGTGGGCATATGAAAGTGTATTTTATCAGATTTATCCGTTAGGCTTCTGTGGGGCACCATTTGAGAATGATGGTGTTTT
GGAACACAGAATTTTAAAAGTGAATGACTGGATACCTCATATCAAAAAGCTTGGGGCAGATGCAATCTATTTTTCACCGG
TGTTTGAATCTGATACACATGGATATAATACAAGGGATTATACAAAAATAGACACAAGGCTTGGCACAAACGAGGACTTC
GCACAGGTTTGTGACAATCTGCACAAGGACGGCATAAAGGTAGTGCTGGATGGTGTGTTCAATCATGTGGGAAGAGGCTT
TTGGGCGTTCCAGGATGTGCTTAAAAACAGAGAAAGCTCACCATATGTGAACTGGTTTGGCCGTATAGCGTTCGATGGCA
ATTCAAACTATAATGATGGATTGTGGTACGAGGGCTGGGAAGGAAACTATGATCTGGTCAAGCTTAATCTGAGAAATGAG
GATGTAATCCAGCATATCTTTTCAGCGATAAAGGGCTGGGTAGACGAGTTTGATATAGACGGGCTGAGACTTGATGTGGC
ATACTGCCTCGACCATGATTTCCTCAGAAGACTAAGGGAGTTCTGCGACTCACTAAAGCCGGATTTCTTCCTGGTGGGAG
AGACACTGCATGGTGACTACAACCAGATTATGAATGATGCGATGCTTCACTCGGTAACGAACTATGAGTGCTATAAGGGT
CTGTACTCGAGCTTTAATTCCATGAATATGTTTGAGATAAATCATTCGCTTCTCAGACAGTTTGGACCGGAGCAGTGGAC
TCTCTACAAGGGTAAGCACCTGCTGTCATTTGTGGACAATCATGATGTGACAAGAGTGGCAAGCATACTGACCAATGAAA
AGCATCTGCCACTAATCTATGCACTTGCATTTGGTATGCCGGGCATCCCTTGTGTGTACTATGGCAGTGAGTGGGGAGAG
AAGGCAAAAAAAGAAGACGGTGACCCGGCTCTGAGGGCATGCTTTGAAGCGCCACAGTGCAATGAGCTGACTGAATGGAT
TTCAAAGCTCGCAGAGGCAAAGAAGCAGTCAAAGGCACTCTGCTACGGTAATTTCTATTCGGTTGTGCTCACAAACGGCC
AGTGCGTTTTCGGTCGTGAATGTGATGGTGAAAAGGTATTCGTGTGCATCAATGCCGCAGACCAGCCGTTTTTCGCGGGC
TTTGATATGGGAAAGGGTGATGCCACAGACCTGATTACAGGTGAGCAGGTTACATTAAACGGTGGCCTTGAGCTGCCACC
TTACAGTGCATACTTTTTGAGATAA

Upstream 100 bases:

>100_bases
AGGTAAAAAGTAACAAAAAAATGTAGCATATAAGTACATAATTGTGTATAATAGATAACAGGTACAAAACCACTACACAA
CTATCAAGGAGGGCAAAATA

Downstream 100 bases:

>100_bases
CATTTGTATGGACAATAAAAGAATTAATAAAAGAAAAAATGAAAGAAAAGAGCTCATATGTGCTGTCACAGCCGTAGTGG
TACTTTACACAGCTATGGAG

Product: cyclomaltodextrinase

Products: NA

Alternate protein names: CDase; Cyclomaltodextrin hydrolase, decycling [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MWAYESVFYQIYPLGFCGAPFENDGVLEHRILKVNDWIPHIKKLGADAIYFSPVFESDTHGYNTRDYTKIDTRLGTNEDF
AQVCDNLHKDGIKVVLDGVFNHVGRGFWAFQDVLKNRESSPYVNWFGRIAFDGNSNYNDGLWYEGWEGNYDLVKLNLRNE
DVIQHIFSAIKGWVDEFDIDGLRLDVAYCLDHDFLRRLREFCDSLKPDFFLVGETLHGDYNQIMNDAMLHSVTNYECYKG
LYSSFNSMNMFEINHSLLRQFGPEQWTLYKGKHLLSFVDNHDVTRVASILTNEKHLPLIYALAFGMPGIPCVYYGSEWGE
KAKKEDGDPALRACFEAPQCNELTEWISKLAEAKKQSKALCYGNFYSVVLTNGQCVFGRECDGEKVFVCINAADQPFFAG
FDMGKGDATDLITGEQVTLNGGLELPPYSAYFLR

Sequences:

>Translated_434_residues
MWAYESVFYQIYPLGFCGAPFENDGVLEHRILKVNDWIPHIKKLGADAIYFSPVFESDTHGYNTRDYTKIDTRLGTNEDF
AQVCDNLHKDGIKVVLDGVFNHVGRGFWAFQDVLKNRESSPYVNWFGRIAFDGNSNYNDGLWYEGWEGNYDLVKLNLRNE
DVIQHIFSAIKGWVDEFDIDGLRLDVAYCLDHDFLRRLREFCDSLKPDFFLVGETLHGDYNQIMNDAMLHSVTNYECYKG
LYSSFNSMNMFEINHSLLRQFGPEQWTLYKGKHLLSFVDNHDVTRVASILTNEKHLPLIYALAFGMPGIPCVYYGSEWGE
KAKKEDGDPALRACFEAPQCNELTEWISKLAEAKKQSKALCYGNFYSVVLTNGQCVFGRECDGEKVFVCINAADQPFFAG
FDMGKGDATDLITGEQVTLNGGLELPPYSAYFLR
>Mature_434_residues
MWAYESVFYQIYPLGFCGAPFENDGVLEHRILKVNDWIPHIKKLGADAIYFSPVFESDTHGYNTRDYTKIDTRLGTNEDF
AQVCDNLHKDGIKVVLDGVFNHVGRGFWAFQDVLKNRESSPYVNWFGRIAFDGNSNYNDGLWYEGWEGNYDLVKLNLRNE
DVIQHIFSAIKGWVDEFDIDGLRLDVAYCLDHDFLRRLREFCDSLKPDFFLVGETLHGDYNQIMNDAMLHSVTNYECYKG
LYSSFNSMNMFEINHSLLRQFGPEQWTLYKGKHLLSFVDNHDVTRVASILTNEKHLPLIYALAFGMPGIPCVYYGSEWGE
KAKKEDGDPALRACFEAPQCNELTEWISKLAEAKKQSKALCYGNFYSVVLTNGQCVFGRECDGEKVFVCINAADQPFFAG
FDMGKGDATDLITGEQVTLNGGLELPPYSAYFLR

Specific function: Hydrolyzes cyclodextrins. Can also act on linear maltodextrins, with the exception of maltose [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Escherichia coli, GI1786604, Length=456, Percent_Identity=25.4385964912281, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790687, Length=376, Percent_Identity=28.4574468085106, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25147709, Length=326, Percent_Identity=20.2453987730061, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322245, Length=259, Percent_Identity=27.4131274131274, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319776, Length=397, Percent_Identity=24.1813602015113, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321731, Length=397, Percent_Identity=24.1813602015113, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321726, Length=210, Percent_Identity=29.0476190476191, Blast_Score=73, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324416, Length=210, Percent_Identity=29.0476190476191, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322241, Length=210, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322021, Length=210, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583749, Length=406, Percent_Identity=26.1083743842365, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583747, Length=406, Percent_Identity=26.1083743842365, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24583745, Length=386, Percent_Identity=25.3886010362694, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004185
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02903 Alpha-amylase_N [H]

EC number: =3.2.1.54 [H]

Molecular weight: Translated: 49634; Mature: 49634

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWAYESVFYQIYPLGFCGAPFENDGVLEHRILKVNDWIPHIKKLGADAIYFSPVFESDTH
CCCHHCCHHEEEECCCCCCCCCCCCCCHHEEEEEHHHHHHHHHCCCCEEEECCCCCCCCC
GYNTRDYTKIDTRLGTNEDFAQVCDNLHKDGIKVVLDGVFNHVGRGFWAFQDVLKNRESS
CCCCCCCEEEHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
PYVNWFGRIAFDGNSNYNDGLWYEGWEGNYDLVKLNLRNEDVIQHIFSAIKGWVDEFDID
CCEEEEEEEEECCCCCCCCCCEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCC
GLRLDVAYCLDHDFLRRLREFCDSLKPDFFLVGETLHGDYNQIMNDAMLHSVTNYECYKG
CEEEEHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHH
LYSSFNSMNMFEINHSLLRQFGPEQWTLYKGKHLLSFVDNHDVTRVASILTNEKHLPLIY
HHHHCCCCEEEEHHHHHHHHCCCCCEEEECCCHHHHHHCCCCHHHHHHHHCCCCCCCCHH
ALAFGMPGIPCVYYGSEWGEKAKKEDGDPALRACFEAPQCNELTEWISKLAEAKKQSKAL
HHHHCCCCCCEEEECCHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEE
CYGNFYSVVLTNGQCVFGRECDGEKVFVCINAADQPFFAGFDMGKGDATDLITGEQVTLN
EECCEEEEEEECCEEEECCCCCCCEEEEEEECCCCCEEECCCCCCCCCCEEECCCEEEEC
GGLELPPYSAYFLR
CCCCCCCCCCCCCC
>Mature Secondary Structure
MWAYESVFYQIYPLGFCGAPFENDGVLEHRILKVNDWIPHIKKLGADAIYFSPVFESDTH
CCCHHCCHHEEEECCCCCCCCCCCCCCHHEEEEEHHHHHHHHHCCCCEEEECCCCCCCCC
GYNTRDYTKIDTRLGTNEDFAQVCDNLHKDGIKVVLDGVFNHVGRGFWAFQDVLKNRESS
CCCCCCCEEEHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
PYVNWFGRIAFDGNSNYNDGLWYEGWEGNYDLVKLNLRNEDVIQHIFSAIKGWVDEFDID
CCEEEEEEEEECCCCCCCCCCEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCC
GLRLDVAYCLDHDFLRRLREFCDSLKPDFFLVGETLHGDYNQIMNDAMLHSVTNYECYKG
CEEEEHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHH
LYSSFNSMNMFEINHSLLRQFGPEQWTLYKGKHLLSFVDNHDVTRVASILTNEKHLPLIY
HHHHCCCCEEEEHHHHHHHHCCCCCEEEECCCHHHHHHCCCCHHHHHHHHCCCCCCCCHH
ALAFGMPGIPCVYYGSEWGEKAKKEDGDPALRACFEAPQCNELTEWISKLAEAKKQSKAL
HHHHCCCCCCEEEECCHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEE
CYGNFYSVVLTNGQCVFGRECDGEKVFVCINAADQPFFAGFDMGKGDATDLITGEQVTLN
EECCEEEEEEECCEEEECCCCCCCEEEEEEECCCCCEEECCCCCCCCCCEEECCCEEEEC
GGLELPPYSAYFLR
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1644767; 8425614 [H]