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The map label for this gene is adcA [H]

Identifier: 238923373

GI number: 238923373

Start: 888927

End: 889955

Strand: Direct

Name: adcA [H]

Synonym: EUBREC_0993

Alternate gene names: 238923373

Gene position: 888927-889955 (Clockwise)

Preceding gene: 238923372

Following gene: 238923374

Centisome position: 25.77

GC content: 45.09

Gene sequence:

>1029_bases
ATGAAGAATAAATGCAAATTTGTAGGCATTATGTTTTTGTGTATATTGATAGTGTGTACGCTTGCGGTAATGGCATATGA
GCACACAGCAGGTATGAAAGGCGCTGCCGGTGGAGCATCAAATGCTTCGGGCAATACAAAAAATACAGACGAAGCTGATG
ATATGCTTACAGTCGTGACATCCTTCTATCCTATGTACATTGCCACTTTAAACATAGTGGATGGTGTGAAAGGAGTGAGA
CTCGAAAATCTGAGCGAGCCACAGACCGGTTGTCTGCACGATTTTCAGCTAACACCGGAGGATATGAAGCTTTTATCCAC
AGCCGATGTTTTTGTAATAAACGGAGGCGGTATAGAGTCGTTTATGTCTGATGTGGCAAAGGCGTATCCGAAGCTTGATG
TGGTTGAGGCCTGTGAGGATGTGGCACTTCTTTCTGAGGATGATGCAGACAGTGACCACGACCATGACCACGAAGCAGAC
GCAGAATCAGATAGCGCGCACGATCATGACCATGGTGATGAGAATGCCCATGCATGGATGAGCGTGCCGCGTTACCGCAC
CATGGTTCAGACAATCGCATCCCAGCTTGCCGAAAAGGATGCAAAGCATGCTGATGAATATTATGCAAATGCAAAAGCAT
ATGATGCAAAGCTTGCAGTGCTTGAAGAAAAGATAAATAGCATAAAGAGTCTTACCAATGGACAGAATATCATCATATTC
CATGAGGCCTATGCGTATGTAGCTGATGATTTTTCCATGAATGCATGCTATCTGTTAGACCTTGACGAGGAGCGCTCAGT
CAGCGCAGGTGAGATAAAGCAGGTAATAGGTGCCATAAAGGATGACGGAGTGTCGGTAATACTCGCTGAGGAGCTCTACG
GAAAGAGCATGGGAGATACCGTATCGCGTGAGACAGATGTGCATGTGATTTATATCGACCCTCTCAACAGGGGAGAGTAC
GACAAGGACAGCTATCTTGATGGTATGGAGCACAATATAGAGCTTATCAAAGAGGCAATTACTAAATAA

Upstream 100 bases:

>100_bases
AAAAAGACTAAAGAACGCAGAGATAAGGCCAAGAGCAAAAAAAGCGTTAATAATCATAAAAAGAAATAAAGCTATAGAAA
GAAAGGCGAATATTTAATAT

Downstream 100 bases:

>100_bases
AATTGGAGAAAATATGCGGAAAATAATACAGCCATGTGGCTTTCATTGCATAAAAATAAATAACCTTGGAGTGAGCTTTG
GAGAGCAGACAGTGCTTGAG

Product: adhesion lipoprotein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKNKCKFVGIMFLCILIVCTLAVMAYEHTAGMKGAAGGASNASGNTKNTDEADDMLTVVTSFYPMYIATLNIVDGVKGVR
LENLSEPQTGCLHDFQLTPEDMKLLSTADVFVINGGGIESFMSDVAKAYPKLDVVEACEDVALLSEDDADSDHDHDHEAD
AESDSAHDHDHGDENAHAWMSVPRYRTMVQTIASQLAEKDAKHADEYYANAKAYDAKLAVLEEKINSIKSLTNGQNIIIF
HEAYAYVADDFSMNACYLLDLDEERSVSAGEIKQVIGAIKDDGVSVILAEELYGKSMGDTVSRETDVHVIYIDPLNRGEY
DKDSYLDGMEHNIELIKEAITK

Sequences:

>Translated_342_residues
MKNKCKFVGIMFLCILIVCTLAVMAYEHTAGMKGAAGGASNASGNTKNTDEADDMLTVVTSFYPMYIATLNIVDGVKGVR
LENLSEPQTGCLHDFQLTPEDMKLLSTADVFVINGGGIESFMSDVAKAYPKLDVVEACEDVALLSEDDADSDHDHDHEAD
AESDSAHDHDHGDENAHAWMSVPRYRTMVQTIASQLAEKDAKHADEYYANAKAYDAKLAVLEEKINSIKSLTNGQNIIIF
HEAYAYVADDFSMNACYLLDLDEERSVSAGEIKQVIGAIKDDGVSVILAEELYGKSMGDTVSRETDVHVIYIDPLNRGEY
DKDSYLDGMEHNIELIKEAITK
>Mature_342_residues
MKNKCKFVGIMFLCILIVCTLAVMAYEHTAGMKGAAGGASNASGNTKNTDEADDMLTVVTSFYPMYIATLNIVDGVKGVR
LENLSEPQTGCLHDFQLTPEDMKLLSTADVFVINGGGIESFMSDVAKAYPKLDVVEACEDVALLSEDDADSDHDHDHEAD
AESDSAHDHDHGDENAHAWMSVPRYRTMVQTIASQLAEKDAKHADEYYANAKAYDAKLAVLEEKINSIKSLTNGQNIIIF
HEAYAYVADDFSMNACYLLDLDEERSVSAGEIKQVIGAIKDDGVSVILAEELYGKSMGDTVSRETDVHVIYIDPLNRGEY
DKDSYLDGMEHNIELIKEAITK

Specific function: Part of the ATP-driven transport system AdcABC for zinc [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=285, Percent_Identity=28.4210526315789, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 37529; Mature: 37529

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKCKFVGIMFLCILIVCTLAVMAYEHTAGMKGAAGGASNASGNTKNTDEADDMLTVVT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
SFYPMYIATLNIVDGVKGVRLENLSEPQTGCLHDFQLTPEDMKLLSTADVFVINGGGIES
HHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCHHH
FMSDVAKAYPKLDVVEACEDVALLSEDDADSDHDHDHEADAESDSAHDHDHGDENAHAWM
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
SVPRYRTMVQTIASQLAEKDAKHADEYYANAKAYDAKLAVLEEKINSIKSLTNGQNIIIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HEAYAYVADDFSMNACYLLDLDEERSVSAGEIKQVIGAIKDDGVSVILAEELYGKSMGDT
ECHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCC
VSRETDVHVIYIDPLNRGEYDKDSYLDGMEHNIELIKEAITK
CCCCCCEEEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNKCKFVGIMFLCILIVCTLAVMAYEHTAGMKGAAGGASNASGNTKNTDEADDMLTVVT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
SFYPMYIATLNIVDGVKGVRLENLSEPQTGCLHDFQLTPEDMKLLSTADVFVINGGGIES
HHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCHHH
FMSDVAKAYPKLDVVEACEDVALLSEDDADSDHDHDHEADAESDSAHDHDHGDENAHAWM
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
SVPRYRTMVQTIASQLAEKDAKHADEYYANAKAYDAKLAVLEEKINSIKSLTNGQNIIIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HEAYAYVADDFSMNACYLLDLDEERSVSAGEIKQVIGAIKDDGVSVILAEELYGKSMGDT
ECHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCC
VSRETDVHVIYIDPLNRGEYDKDSYLDGMEHNIELIKEAITK
CCCCCCEEEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]