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The map label for this gene is idi2 [H]

Identifier: 238923162

GI number: 238923162

Start: 694525

End: 695178

Strand: Direct

Name: idi2 [H]

Synonym: EUBREC_0755

Alternate gene names: 238923162

Gene position: 694525-695178 (Clockwise)

Preceding gene: 238923161

Following gene: 238923163

Centisome position: 20.13

GC content: 32.42

Gene sequence:

>654_bases
ATGACAAATCGAGGTATAAGTATGAATGATTATATTATTCTTGTAAATGAACAGGATGAAACGATTGGATATTCAGAGAA
AATGGATGCTCACAAAAATGGAAAGTTACATCGAGCGTTCTCAATCTTCATATTTGATTGGAATACTAAAAAGATGCTCA
TACAGAAAAGAGCATTTGAAAAGTATCATTCAGGAGGGCTTTGGACTAATGCTTGTTGTTCACATCCACTTAAAGATGAA
ACCATGGTGAGATGTTTAAATACAAGACTAGCAGAGGAGCTAGGATTGTGTACAGACTTTAATATTAAAGCTCCATCGGA
TTGTGGTTTACTAATTCATGGTGAGGATGTAATCTATAGTTGCGGTAAATTTTCATATTTTGCTTCCTTTGGTGAAGTTG
TTGAAAATGAAATAGACCATGTTTTTTTATACAGTCCAATTAAAAGTAAAATTGATTTGACAGCTATATCTTTTAATAAA
CAAGAAATAGAAGAAATCAAATGGATAAGCATTGAAGAACTGAAAAGTTGGATGGAGAGTAATCCTGAGGATTTTACAGC
GTGGTTCAAATCTGCTTTTGAACTTGCTTATATTGTGTTTTGCAGACAAGCTGGAAATATAGATATGTTCTTTGACAATG
ATGAGTATAGATAA

Upstream 100 bases:

>100_bases
GCTGGTAATCCAATGCATTTGATATGTGATAATGTTGAGTGGACTAATTAGTTAAAAATATTCGAGGGGATTGATTGGTA
ATAGATTGTTGTATTAGTAA

Downstream 100 bases:

>100_bases
AAGAGGAGATATCAATAATGAAGAGAGCAATTTGTTTTATACTTTGCGCAATTACGATAATGTCATCTACATATACGGCA
TTAGCTACAGAAACAACTGA

Product: diphosphomevalonate decarboxylase/isopentenyl-diphosphate delta-isomerase

Products: NA

Alternate protein names: IPP isomerase 2; IPP:DMAPP isomerase 2; Isopentenyl pyrophosphate isomerase 2 [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MTNRGISMNDYIILVNEQDETIGYSEKMDAHKNGKLHRAFSIFIFDWNTKKMLIQKRAFEKYHSGGLWTNACCSHPLKDE
TMVRCLNTRLAEELGLCTDFNIKAPSDCGLLIHGEDVIYSCGKFSYFASFGEVVENEIDHVFLYSPIKSKIDLTAISFNK
QEIEEIKWISIEELKSWMESNPEDFTAWFKSAFELAYIVFCRQAGNIDMFFDNDEYR

Sequences:

>Translated_217_residues
MTNRGISMNDYIILVNEQDETIGYSEKMDAHKNGKLHRAFSIFIFDWNTKKMLIQKRAFEKYHSGGLWTNACCSHPLKDE
TMVRCLNTRLAEELGLCTDFNIKAPSDCGLLIHGEDVIYSCGKFSYFASFGEVVENEIDHVFLYSPIKSKIDLTAISFNK
QEIEEIKWISIEELKSWMESNPEDFTAWFKSAFELAYIVFCRQAGNIDMFFDNDEYR
>Mature_216_residues
TNRGISMNDYIILVNEQDETIGYSEKMDAHKNGKLHRAFSIFIFDWNTKKMLIQKRAFEKYHSGGLWTNACCSHPLKDET
MVRCLNTRLAEELGLCTDFNIKAPSDCGLLIHGEDVIYSCGKFSYFASFGEVVENEIDHVFLYSPIKSKIDLTAISFNKQ
EIEEIKWISIEELKSWMESNPEDFTAWFKSAFELAYIVFCRQAGNIDMFFDNDEYR

Specific function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) [H]

COG id: COG1443

COG function: function code I; Isopentenyldiphosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI40018633, Length=103, Percent_Identity=36.8932038834951, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1789255, Length=183, Percent_Identity=27.3224043715847, Blast_Score=67, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17554092, Length=192, Percent_Identity=32.8125, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325140, Length=198, Percent_Identity=35.8585858585859, Blast_Score=86, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281362205, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648688, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011876
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =5.3.3.2 [H]

Molecular weight: Translated: 25233; Mature: 25102

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRGISMNDYIILVNEQDETIGYSEKMDAHKNGKLHRAFSIFIFDWNTKKMLIQKRAFE
CCCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHH
KYHSGGLWTNACCSHPLKDETMVRCLNTRLAEELGLCTDFNIKAPSDCGLLIHGEDVIYS
HHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHEEE
CGKFSYFASFGEVVENEIDHVFLYSPIKSKIDLTAISFNKQEIEEIKWISIEELKSWMES
CCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCHHHHHHHCCCCHHHHHHHHHC
NPEDFTAWFKSAFELAYIVFCRQAGNIDMFFDNDEYR
CCHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCC
>Mature Secondary Structure 
TNRGISMNDYIILVNEQDETIGYSEKMDAHKNGKLHRAFSIFIFDWNTKKMLIQKRAFE
CCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHH
KYHSGGLWTNACCSHPLKDETMVRCLNTRLAEELGLCTDFNIKAPSDCGLLIHGEDVIYS
HHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHEEE
CGKFSYFASFGEVVENEIDHVFLYSPIKSKIDLTAISFNKQEIEEIKWISIEELKSWMES
CCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCHHHHHHHCCCCHHHHHHHHHC
NPEDFTAWFKSAFELAYIVFCRQAGNIDMFFDNDEYR
CCHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA