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The map label for this gene is yhdR [H]

Identifier: 238922971

GI number: 238922971

Start: 519118

End: 520311

Strand: Direct

Name: yhdR [H]

Synonym: EUBREC_0560

Alternate gene names: 238922971

Gene position: 519118-520311 (Clockwise)

Preceding gene: 238922970

Following gene: 238922972

Centisome position: 15.05

GC content: 46.06

Gene sequence:

>1194_bases
ATGGTAGTAAACGAAAGCATGTACCAGCTCGGAAGCGTGCGCTCAGCAATCAGGGAGCTTTTTGAGTATGGTAAAAAAAG
AGCAGCAATTGTAGGTAAGGAAAATGTATATGATTTCTCAATAGGAAACCCGAGCATACCGGCTCCGCAGATAGTAAACG
ACACAATAAAGGAGCTTGTGACAGATTATGATTCTGTTGCGCTGCACGGCTACACCTCAGCACAGGGAGACGTGGAAACG
AGAGCGGCAATAGCTGAATTTTTGAACAACACACATGGCACACATTTTAATGCAGACAACCTTTACATGACAATGGGAGC
AGCGGCATCGCTGTCAATCTGCTTTCGTGCGTTGACAAGTGACGCATATGATGAGTTTATTACCATAGCGCCATATTTCC
CGGAGTACAAGGTATTTGTGAATGCAGCAGGAGCAAGGCTTGTAGAGGTGCCTGCAGACACAGAGCATTTTCAGATAGAT
TTCGATGCGCTTGAGGAGAGAATCAATGCGCACACCAGAGGTGTCATAATTAATTCACCAAACAACCCATCCGGCACAGT
CTATTCTGAGGAGACCATCAAAAAGCTCTCAGACCTCCTTGAGAAAAAGTCTAAGGAGATAGGAAGACCGATATTCATTA
TCGCAGATGAGCCGTACAGGGAGATAGTTTACGACGGAATCAAGGTACCGTTTGTGACCAAATATTACGACAACACACTG
GTATGCTACTCATACAGCAAGTCACTTTCACTGCCGGGAGAGAGAATAGGATACGTCCTCGTGCCTGATGAGGTGTACGA
TAAGGCAGAGCTGTATGCAGCAGTCTGTGGTGCGGGAAGAGCACTCGGTTACGTGTGTGCACCAAGCCTGTTCCAGAAGA
TGATAGTAAAATGCCAGGGGGCAACCGGTGATATCAATGCCTACAAAGAAAACAGAGACCTTCTGTATGAGGGACTCACA
AGGATAGGCTATCACTGCTTCAAGCCGGACGGAGCCTTTTATATGTTTGTAAAGGCACTCGAGGATGACAGCAATGCATT
CTGTGAGAAGGCAAAGGAGGAGGATGTGCTCATAGTAGCAGCAGACGGCTTCGGCTGTCCGGGCTGGGTGAGAATATCAT
ACTGTGTGGACAGGGAAATGATAAAGCACTCTATGCCTGCGTTTGAAAAGATATACAAGAAATATAATAAATAA

Upstream 100 bases:

>100_bases
TATGTGTATAAAGAGATGTTTATAAAGATATTTGTATGTCATAAGCAGAGATATTATAATAGTAAACATGCAAGAACATC
AGAGATAAGGAGACAAGAAA

Downstream 100 bases:

>100_bases
TAGTTATAAAAAAATAATCCGAAAAAGCGTCGAAAATTGTCTAAAAAATATGTAATTTTCGGCGCTTTTATTATGCAGTT
TTCACAAAGTTGTCTCCGTG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MVVNESMYQLGSVRSAIRELFEYGKKRAAIVGKENVYDFSIGNPSIPAPQIVNDTIKELVTDYDSVALHGYTSAQGDVET
RAAIAEFLNNTHGTHFNADNLYMTMGAAASLSICFRALTSDAYDEFITIAPYFPEYKVFVNAAGARLVEVPADTEHFQID
FDALEERINAHTRGVIINSPNNPSGTVYSEETIKKLSDLLEKKSKEIGRPIFIIADEPYREIVYDGIKVPFVTKYYDNTL
VCYSYSKSLSLPGERIGYVLVPDEVYDKAELYAAVCGAGRALGYVCAPSLFQKMIVKCQGATGDINAYKENRDLLYEGLT
RIGYHCFKPDGAFYMFVKALEDDSNAFCEKAKEEDVLIVAADGFGCPGWVRISYCVDREMIKHSMPAFEKIYKKYNK

Sequences:

>Translated_397_residues
MVVNESMYQLGSVRSAIRELFEYGKKRAAIVGKENVYDFSIGNPSIPAPQIVNDTIKELVTDYDSVALHGYTSAQGDVET
RAAIAEFLNNTHGTHFNADNLYMTMGAAASLSICFRALTSDAYDEFITIAPYFPEYKVFVNAAGARLVEVPADTEHFQID
FDALEERINAHTRGVIINSPNNPSGTVYSEETIKKLSDLLEKKSKEIGRPIFIIADEPYREIVYDGIKVPFVTKYYDNTL
VCYSYSKSLSLPGERIGYVLVPDEVYDKAELYAAVCGAGRALGYVCAPSLFQKMIVKCQGATGDINAYKENRDLLYEGLT
RIGYHCFKPDGAFYMFVKALEDDSNAFCEKAKEEDVLIVAADGFGCPGWVRISYCVDREMIKHSMPAFEKIYKKYNK
>Mature_397_residues
MVVNESMYQLGSVRSAIRELFEYGKKRAAIVGKENVYDFSIGNPSIPAPQIVNDTIKELVTDYDSVALHGYTSAQGDVET
RAAIAEFLNNTHGTHFNADNLYMTMGAAASLSICFRALTSDAYDEFITIAPYFPEYKVFVNAAGARLVEVPADTEHFQID
FDALEERINAHTRGVIINSPNNPSGTVYSEETIKKLSDLLEKKSKEIGRPIFIIADEPYREIVYDGIKVPFVTKYYDNTL
VCYSYSKSLSLPGERIGYVLVPDEVYDKAELYAAVCGAGRALGYVCAPSLFQKMIVKCQGATGDINAYKENRDLLYEGLT
RIGYHCFKPDGAFYMFVKALEDDSNAFCEKAKEEDVLIVAADGFGCPGWVRISYCVDREMIKHSMPAFEKIYKKYNK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=326, Percent_Identity=23.9263803680982, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI169881279, Length=326, Percent_Identity=23.9263803680982, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=23.6074270557029, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI56713254, Length=329, Percent_Identity=24.3161094224924, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI56713256, Length=329, Percent_Identity=24.3161094224924, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI169881281, Length=228, Percent_Identity=24.1228070175439, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1788627, Length=412, Percent_Identity=25.7281553398058, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788722, Length=386, Percent_Identity=24.8704663212435, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786816, Length=336, Percent_Identity=21.4285714285714, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17567369, Length=324, Percent_Identity=25.6172839506173, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17567663, Length=395, Percent_Identity=23.2911392405063, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=314, Percent_Identity=24.8407643312102, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=314, Percent_Identity=24.8407643312102, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=305, Percent_Identity=24.9180327868852, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI18859735, Length=373, Percent_Identity=26.2734584450402, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28573069, Length=320, Percent_Identity=24.375, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24646114, Length=320, Percent_Identity=24.375, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI28573067, Length=320, Percent_Identity=24.375, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI28573065, Length=320, Percent_Identity=24.375, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44391; Mature: 44391

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVNESMYQLGSVRSAIRELFEYGKKRAAIVGKENVYDFSIGNPSIPAPQIVNDTIKELV
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHH
TDYDSVALHGYTSAQGDVETRAAIAEFLNNTHGTHFNADNLYMTMGAAASLSICFRALTS
HCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
DAYDEFITIAPYFPEYKVFVNAAGARLVEVPADTEHFQIDFDALEERINAHTRGVIINSP
HHHHCEEEECCCCCCEEEEEEECCCEEEECCCCCCEEEEEHHHHHHHHCHHHCEEEEECC
NNPSGTVYSEETIKKLSDLLEKKSKEIGRPIFIIADEPYREIVYDGIKVPFVTKYYDNTL
CCCCCCEECHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHCCCCCCEEEEECCCEE
VCYSYSKSLSLPGERIGYVLVPDEVYDKAELYAAVCGAGRALGYVCAPSLFQKMIVKCQG
EEEEECCCCCCCHHHCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
ATGDINAYKENRDLLYEGLTRIGYHCFKPDGAFYMFVKALEDDSNAFCEKAKEEDVLIVA
CCCCCCCHHCCHHHHHHHHHHHCCEEECCCCCEEEEEEECCCCCHHHHHHCCCCCEEEEE
ADGFGCPGWVRISYCVDREMIKHSMPAFEKIYKKYNK
ECCCCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MVVNESMYQLGSVRSAIRELFEYGKKRAAIVGKENVYDFSIGNPSIPAPQIVNDTIKELV
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHH
TDYDSVALHGYTSAQGDVETRAAIAEFLNNTHGTHFNADNLYMTMGAAASLSICFRALTS
HCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
DAYDEFITIAPYFPEYKVFVNAAGARLVEVPADTEHFQIDFDALEERINAHTRGVIINSP
HHHHCEEEECCCCCCEEEEEEECCCEEEECCCCCCEEEEEHHHHHHHHCHHHCEEEEECC
NNPSGTVYSEETIKKLSDLLEKKSKEIGRPIFIIADEPYREIVYDGIKVPFVTKYYDNTL
CCCCCCEECHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHCCCCCCEEEEECCCEE
VCYSYSKSLSLPGERIGYVLVPDEVYDKAELYAAVCGAGRALGYVCAPSLFQKMIVKCQG
EEEEECCCCCCCHHHCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
ATGDINAYKENRDLLYEGLTRIGYHCFKPDGAFYMFVKALEDDSNAFCEKAKEEDVLIVA
CCCCCCCHHCCHHHHHHHHHHHCCEEECCCCCEEEEEEECCCCCHHHHHHCCCCCEEEEE
ADGFGCPGWVRISYCVDREMIKHSMPAFEKIYKKYNK
ECCCCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]