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The map label for this gene is malE [C]

Identifier: 238922953

GI number: 238922953

Start: 501287

End: 502612

Strand: Direct

Name: malE [C]

Synonym: EUBREC_0542

Alternate gene names: 238922953

Gene position: 501287-502612 (Clockwise)

Preceding gene: 238922952

Following gene: 238922954

Centisome position: 14.53

GC content: 42.23

Gene sequence:

>1326_bases
TTGCACGGCAATTTATATATATACTTTTTTACATTTTATATTCAAAAAGGAGAGGAAGATATGAAGAAGAAAGTATTAGC
ATCTTTACTTTGCGCATCTATGGTAGCAACAATGTTTGCAGGATGCGGAAGCAGCAATGGAAATGGAACAGAGAAAGCCG
ACAAGAAGGCCGGCGGTAAGGAGACCATTACAGTAATGGGACCTTCAGAGGACTTAGATGATGCAAAGGGTGCTTGGCTC
AAGACAGAGTGCGAGGCATTTGCTAAAGCAAATCCTGATTTCAACATCGAGTTCAAGTATGTTACATCATCTGAGAGTGA
TGCAAAGGACGTTGTTACAAAGGATCCTAAGGCAGCAGCTGATGTTTACATGTTTGCAAACGATCAGCTTGAGCCATTAA
TTAAGGCTAATGCTATTGCTAAGTTAGGTGGAGAGGCAGCAGATTATGTTAAGACATCTAACTCAGAGGCTATGGCAGCA
ACTGTTACATATGATGGAGACATCTACGCAGTTCCTTATACATCAAACACATGGTTCATGTACTATGACAAGAGAGTTTT
CTCTGAGGATGATGTAAAGAGCCTTGATACAATGCTTACAAAGGGTAAGGTTTCATTCCCATTTGATAACGGCTGGTATC
TCAATGCATTCTATGCAGCAAACGGATGTACAATCTTCGGAGACGGAACAGACAAGGCTGCCGGATATGATTTCAGCGGA
GATAAGGCAGTAGCAGTTACAAACTACATCGTAGATTTATTTGCAAATCCAAACTTCGTAATGGATAACAATGAGGGATC
ACTTGGTCTTGCTGGACTTAAGGATGGTTCAGTAAACGCTTACTTCAATGGTAACTGGAACTATGACGCAGTTAAAGAGG
CACTTGGTGAGGAGAACGTTGGTGTTGCAGCTCTTCCTACAATCAATATTGGTGGAAAAGACTGCCAGTTAAAGGCATTC
TTAGGATCTAAGGCTATCGGTGTTAACCCTAACTGCAAGAACCAGGAAGTAGCAGTTAAGCTTGCAGCATTCCTTGGAAG
TGAGGATGCACAGCTTGCTCACTTCAAGTTAAGAGCACAGGCTCCTGTAAACAAAGATCTTGTAACAAACGAGGAAATCG
CAGCAGATCCTGTAGCAGCAGCTATGGCTAAGGTTTCATCTGATTGTTCAGTAGCACAGCCTATCATTGATATGGCAGGT
TACTGGGATGCAGCTACACCATTCGGTGATGCTTTCCAGAACGGTGCAGAAGGCCAGATTACAAAGGACAATGCAGCTCA
GAAGACAGAGGACTTCAATACTCAGCTTAATGATTCTCTTAAATAA

Upstream 100 bases:

>100_bases
ATGGCGCATGACAAGTAAGCCACACAGATTGGACAACGAAAAGATAGCCTGGATTAGAAACATTGCGGTGGTTTACCGCA
GATAATTAATTTGATATAAG

Downstream 100 bases:

>100_bases
TTAAGTAGATCAGATTATGATTCCAAGGTTCCGGGTAGCCGGAATCTTGGAATAAATTAGTTTAAAGGATTGGCATATAT
AATGCATGCCAGGAGGAAAA

Product: putative sugar-binding secreted protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: Maltose/Maltodextrin Transporter; Maltose/Maltodextrin ABC Transporter Periplasmic Protein; ABC-Type Sugar Transport System Periplasmic Component; Maltose ABC Transporter Permease; Maltose ABC Transporter; Maltose/Maltodextrin ABC Transporter; Sugar ABC Transporter

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MHGNLYIYFFTFYIQKGEEDMKKKVLASLLCASMVATMFAGCGSSNGNGTEKADKKAGGKETITVMGPSEDLDDAKGAWL
KTECEAFAKANPDFNIEFKYVTSSESDAKDVVTKDPKAAADVYMFANDQLEPLIKANAIAKLGGEAADYVKTSNSEAMAA
TVTYDGDIYAVPYTSNTWFMYYDKRVFSEDDVKSLDTMLTKGKVSFPFDNGWYLNAFYAANGCTIFGDGTDKAAGYDFSG
DKAVAVTNYIVDLFANPNFVMDNNEGSLGLAGLKDGSVNAYFNGNWNYDAVKEALGEENVGVAALPTINIGGKDCQLKAF
LGSKAIGVNPNCKNQEVAVKLAAFLGSEDAQLAHFKLRAQAPVNKDLVTNEEIAADPVAAAMAKVSSDCSVAQPIIDMAG
YWDAATPFGDAFQNGAEGQITKDNAAQKTEDFNTQLNDSLK

Sequences:

>Translated_441_residues
MHGNLYIYFFTFYIQKGEEDMKKKVLASLLCASMVATMFAGCGSSNGNGTEKADKKAGGKETITVMGPSEDLDDAKGAWL
KTECEAFAKANPDFNIEFKYVTSSESDAKDVVTKDPKAAADVYMFANDQLEPLIKANAIAKLGGEAADYVKTSNSEAMAA
TVTYDGDIYAVPYTSNTWFMYYDKRVFSEDDVKSLDTMLTKGKVSFPFDNGWYLNAFYAANGCTIFGDGTDKAAGYDFSG
DKAVAVTNYIVDLFANPNFVMDNNEGSLGLAGLKDGSVNAYFNGNWNYDAVKEALGEENVGVAALPTINIGGKDCQLKAF
LGSKAIGVNPNCKNQEVAVKLAAFLGSEDAQLAHFKLRAQAPVNKDLVTNEEIAADPVAAAMAKVSSDCSVAQPIIDMAG
YWDAATPFGDAFQNGAEGQITKDNAAQKTEDFNTQLNDSLK
>Mature_441_residues
MHGNLYIYFFTFYIQKGEEDMKKKVLASLLCASMVATMFAGCGSSNGNGTEKADKKAGGKETITVMGPSEDLDDAKGAWL
KTECEAFAKANPDFNIEFKYVTSSESDAKDVVTKDPKAAADVYMFANDQLEPLIKANAIAKLGGEAADYVKTSNSEAMAA
TVTYDGDIYAVPYTSNTWFMYYDKRVFSEDDVKSLDTMLTKGKVSFPFDNGWYLNAFYAANGCTIFGDGTDKAAGYDFSG
DKAVAVTNYIVDLFANPNFVMDNNEGSLGLAGLKDGSVNAYFNGNWNYDAVKEALGEENVGVAALPTINIGGKDCQLKAF
LGSKAIGVNPNCKNQEVAVKLAAFLGSEDAQLAHFKLRAQAPVNKDLVTNEEIAADPVAAAMAKVSSDCSVAQPIIDMAG
YWDAATPFGDAFQNGAEGQITKDNAAQKTEDFNTQLNDSLK

Specific function: Involved In The High-Affinity Maltose Membrane Transport System Malefgk. Initial Receptor For The Active Transport Of And Chemotaxis Toward Maltooligosaccharides. [C]

COG id: COG2182

COG function: function code G; Maltose-binding periplasmic proteins/domains

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47341; Mature: 47341

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGNLYIYFFTFYIQKGEEDMKKKVLASLLCASMVATMFAGCGSSNGNGTEKADKKAGGK
CCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCC
ETITVMGPSEDLDDAKGAWLKTECEAFAKANPDFNIEFKYVTSSESDAKDVVTKDPKAAA
EEEEEECCCCCCCCCCCCEEEHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHCCCCCCCE
DVYMFANDQLEPLIKANAIAKLGGEAADYVKTSNSEAMAATVTYDGDIYAVPYTSNTWFM
EEEEEECCCCCHHHHHHHHHHHCCCHHHHEECCCCCEEEEEEEECCEEEEEEECCCEEEE
YYDKRVFSEDDVKSLDTMLTKGKVSFPFDNGWYLNAFYAANGCTIFGDGTDKAAGYDFSG
EECCEECCCCHHHHHHHHHHCCEEECCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCC
DKAVAVTNYIVDLFANPNFVMDNNEGSLGLAGLKDGSVNAYFNGNWNYDAVKEALGEENV
CCEEEEEEEHHHHCCCCCEEEECCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHCCCCC
GVAALPTINIGGKDCQLKAFLGSKAIGVNPNCKNQEVAVKLAAFLGSEDAQLAHFKLRAQ
CEEEEEEEECCCCCEEEEEEECCCEECCCCCCCCHHHHEEEEHHHCCCCCEEEEEEEEEC
APVNKDLVTNEEIAADPVAAAMAKVSSDCSVAQPIIDMAGYWDAATPFGDAFQNGAEGQI
CCCCCCCCCCCHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEE
TKDNAAQKTEDFNTQLNDSLK
ECCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MHGNLYIYFFTFYIQKGEEDMKKKVLASLLCASMVATMFAGCGSSNGNGTEKADKKAGGK
CCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCC
ETITVMGPSEDLDDAKGAWLKTECEAFAKANPDFNIEFKYVTSSESDAKDVVTKDPKAAA
EEEEEECCCCCCCCCCCCEEEHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHCCCCCCCE
DVYMFANDQLEPLIKANAIAKLGGEAADYVKTSNSEAMAATVTYDGDIYAVPYTSNTWFM
EEEEEECCCCCHHHHHHHHHHHCCCHHHHEECCCCCEEEEEEEECCEEEEEEECCCEEEE
YYDKRVFSEDDVKSLDTMLTKGKVSFPFDNGWYLNAFYAANGCTIFGDGTDKAAGYDFSG
EECCEECCCCHHHHHHHHHHCCEEECCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCC
DKAVAVTNYIVDLFANPNFVMDNNEGSLGLAGLKDGSVNAYFNGNWNYDAVKEALGEENV
CCEEEEEEEHHHHCCCCCEEEECCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHCCCCC
GVAALPTINIGGKDCQLKAFLGSKAIGVNPNCKNQEVAVKLAAFLGSEDAQLAHFKLRAQ
CEEEEEEEECCCCCEEEEEEECCCEECCCCCCCCHHHHEEEEHHHCCCCCEEEEEEEEEC
APVNKDLVTNEEIAADPVAAAMAKVSSDCSVAQPIIDMAGYWDAATPFGDAFQNGAEGQI
CCCCCCCCCCCHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEE
TKDNAAQKTEDFNTQLNDSLK
ECCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA