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The map label for this gene is yicI [C]

Identifier: 238922912

GI number: 238922912

Start: 463541

End: 465787

Strand: Direct

Name: yicI [C]

Synonym: EUBREC_0500

Alternate gene names: 238922912

Gene position: 463541-465787 (Clockwise)

Preceding gene: 238922911

Following gene: 238922915

Centisome position: 13.44

GC content: 45.26

Gene sequence:

>2247_bases
ATGGGAAATTTATATAAGAACTGTAAAATACAGGACAACACAGCAGAGCTGATCTACGAGAACGGCAGTCTGTTTGTTAC
CATATTTGAAAACAACATAGTGCATGTTGCACAAAAACACGGCATCGAAAGTGTTGCAATAGAAGAGGACTTTATTCCGA
AGGCTGCCACACCGGACGTGACCTGCAAGGATACGTCTGATGCCAAGGGGACCGCAGCAGAAGCCGGTGTAAGCGATGCA
GCAGTTAAAGCAGTCATAAGTGCAAGGGATATTACTGTAAATGTAAAGGATAACGAGAAGCTTGATATTTATTACAAAGG
GAAGCTTGTGCTTTCGGATTATGAAACAGCACGCAAAAAGAGTGAGAAGAATCCGTACGAGGATCTTGCCATCGCAGAGC
TTGAGGGACATACTGTCGGAAAAGATGAAGAAAAAACTGACGCTGTTACCATCATCAAAAAGCTTGGAAAGGATGATGCT
ATTTACGGTCTGGGAGATAAGCCGGGATGCCTCAACAAGCGTGGATATTCATATGTAAACTGGAACACGGATGATCCTGC
GCCACATGTGGACAGCTTCAAATCGCTGTACAAATCCATACCGTTTTTTATCGTGTTGGGCGATGAATATTGCTATGGAA
TTTTTGCGGATAATACCTACAAGACAACCTTTGATTTCGGTTATGAAAACACAGATTACTATTTCGTCGAGCATGAGAAG
GGCGAGCTGGACTACTATTTTATGCCGGGAAATGATATGGCAGAGGTGGTAGGACTTTATACATCACTGACAGGCACCAC
ACCGCTTTATCAGAGATGGATATACGGCAGCCATCAAAGCCGCTGGGGCTATTACACACAGGATGAGGTACTTGATATAG
CTGACAAATTCCGCGAACTTGATATCCCATGCGATGTGATACATATGGATATCGATTACATGAACGGCTACAGGGTATTC
ACCTTTGATGACAAGAAATTCCCGGATGTAAAGGGCCTTTCAGAGAAGCTTGCTGACAGGGGTGTAAAGCTCATATCCAT
CATTGACCCGGGTGTGAAAAAGGATGAGGATTATTTCATGTACAAAGAGGGCATGGAGATGGATGCATTTGCACATGATA
CAGATGGCAGTGTATATGAAAATGCTGTCTGGCCGGGAACATCGGTATTTCCGGACTTCACAAAGCAAAGCGTCAGAAGC
TGGTGGGGAGACAAGACCAAGATACTTCTCGAGCACGGTATCAGTGGCATATGGAATGATATGAATGAGCCTGCAAGCTT
CAACGGACCACTGCCGGATGATGTGCAGTTTGAGTATGGAGCACATGAAAAGGTTCACAATATTTACGGACATTTTATGG
CAAAAGCTACATATGAGGGACTTGCGAAAAATGATGGTGGAAAACGTCCGTTTGTACTTACAAGGGCTGCATATGCCGGA
AGCCAGAAATACTGCGGTGGCTGGACCGGAGACAATCACAGCATCTGGGCGCATATAGCACTTTCGCTCGAGCAGGTCTG
CAATCTGTCAGTCAGCGGACTTGCCATGTGTGGCAGCGATATAGGCGGTTTCGGAAGTGATACTACACCGGAGCTTCTTG
TCAGATTTTATGAGGCAGCAGTATTTGTGCCGTTTTTCAGAAATCATTCAGCGATGGGAACACGCAGACAGGAGCCTTGG
CAGTTTGACGAGACTACGATAGATGCAGTCAGAAAGACAGTAAAGCTCAGATACAGATTTATCCCATATATCTATGATCT
GGCACATGAGTGTGAGAAGACAGGAGCACCTATCGTGCGCCCGCTCGTATACGAGTATCATGCAGATAAGCATGTGAGAA
ATATTTCCGATGAATATATGCTCGGAAGCTTTGTACTGGTTGCACCTGTGATCGCACCGGGCAAGGAGGCAAGAGAGGTT
TATCTGCCTGACGGCGACTGGTATGATTACTACACAGGCGAAAAATACAGTGGCGGCAGATATATTTTAGCAGATGCACC
ACTTGATAAAGTACCTGTCTTCATAAAAGCAGGAGCCATTATCCCTGTTGCAGACGGAGAAATTCGCTCTACAGAGGACA
TTACAGAGGATAAGATCAGCATACTGACATATCCGGGCAAGGGCAGCTTCGTGCATTATCAGGATGACAATGAGACGTTT
GCATACAGAAACGGTGCGTACAATGCTGTTGAGTATACACTGGATGGGGATAAGCTCGAGAAGAAAGTGTTGCATAAGGG
ATTGTAA

Upstream 100 bases:

>100_bases
TGTTGTAAAAATTAAAAATGGATGATACTATTATAGTAAACGGAAGTATTTTTATAAGAAACATCAGGAGAAACTATATA
ATTCAAGGGAGGATTATGCA

Downstream 100 bases:

>100_bases
AAATACATAACCTTAAATTTAAAATTCAATATCAACCTCAACAGGGCAGTGGTCTGAACCGAGCACATCGGTATGGATTG
CTGCCTTTTTAAGCTTATCA

Product: alpha-glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 748; Mature: 747

Protein sequence:

>748_residues
MGNLYKNCKIQDNTAELIYENGSLFVTIFENNIVHVAQKHGIESVAIEEDFIPKAATPDVTCKDTSDAKGTAAEAGVSDA
AVKAVISARDITVNVKDNEKLDIYYKGKLVLSDYETARKKSEKNPYEDLAIAELEGHTVGKDEEKTDAVTIIKKLGKDDA
IYGLGDKPGCLNKRGYSYVNWNTDDPAPHVDSFKSLYKSIPFFIVLGDEYCYGIFADNTYKTTFDFGYENTDYYFVEHEK
GELDYYFMPGNDMAEVVGLYTSLTGTTPLYQRWIYGSHQSRWGYYTQDEVLDIADKFRELDIPCDVIHMDIDYMNGYRVF
TFDDKKFPDVKGLSEKLADRGVKLISIIDPGVKKDEDYFMYKEGMEMDAFAHDTDGSVYENAVWPGTSVFPDFTKQSVRS
WWGDKTKILLEHGISGIWNDMNEPASFNGPLPDDVQFEYGAHEKVHNIYGHFMAKATYEGLAKNDGGKRPFVLTRAAYAG
SQKYCGGWTGDNHSIWAHIALSLEQVCNLSVSGLAMCGSDIGGFGSDTTPELLVRFYEAAVFVPFFRNHSAMGTRRQEPW
QFDETTIDAVRKTVKLRYRFIPYIYDLAHECEKTGAPIVRPLVYEYHADKHVRNISDEYMLGSFVLVAPVIAPGKEAREV
YLPDGDWYDYYTGEKYSGGRYILADAPLDKVPVFIKAGAIIPVADGEIRSTEDITEDKISILTYPGKGSFVHYQDDNETF
AYRNGAYNAVEYTLDGDKLEKKVLHKGL

Sequences:

>Translated_748_residues
MGNLYKNCKIQDNTAELIYENGSLFVTIFENNIVHVAQKHGIESVAIEEDFIPKAATPDVTCKDTSDAKGTAAEAGVSDA
AVKAVISARDITVNVKDNEKLDIYYKGKLVLSDYETARKKSEKNPYEDLAIAELEGHTVGKDEEKTDAVTIIKKLGKDDA
IYGLGDKPGCLNKRGYSYVNWNTDDPAPHVDSFKSLYKSIPFFIVLGDEYCYGIFADNTYKTTFDFGYENTDYYFVEHEK
GELDYYFMPGNDMAEVVGLYTSLTGTTPLYQRWIYGSHQSRWGYYTQDEVLDIADKFRELDIPCDVIHMDIDYMNGYRVF
TFDDKKFPDVKGLSEKLADRGVKLISIIDPGVKKDEDYFMYKEGMEMDAFAHDTDGSVYENAVWPGTSVFPDFTKQSVRS
WWGDKTKILLEHGISGIWNDMNEPASFNGPLPDDVQFEYGAHEKVHNIYGHFMAKATYEGLAKNDGGKRPFVLTRAAYAG
SQKYCGGWTGDNHSIWAHIALSLEQVCNLSVSGLAMCGSDIGGFGSDTTPELLVRFYEAAVFVPFFRNHSAMGTRRQEPW
QFDETTIDAVRKTVKLRYRFIPYIYDLAHECEKTGAPIVRPLVYEYHADKHVRNISDEYMLGSFVLVAPVIAPGKEAREV
YLPDGDWYDYYTGEKYSGGRYILADAPLDKVPVFIKAGAIIPVADGEIRSTEDITEDKISILTYPGKGSFVHYQDDNETF
AYRNGAYNAVEYTLDGDKLEKKVLHKGL
>Mature_747_residues
GNLYKNCKIQDNTAELIYENGSLFVTIFENNIVHVAQKHGIESVAIEEDFIPKAATPDVTCKDTSDAKGTAAEAGVSDAA
VKAVISARDITVNVKDNEKLDIYYKGKLVLSDYETARKKSEKNPYEDLAIAELEGHTVGKDEEKTDAVTIIKKLGKDDAI
YGLGDKPGCLNKRGYSYVNWNTDDPAPHVDSFKSLYKSIPFFIVLGDEYCYGIFADNTYKTTFDFGYENTDYYFVEHEKG
ELDYYFMPGNDMAEVVGLYTSLTGTTPLYQRWIYGSHQSRWGYYTQDEVLDIADKFRELDIPCDVIHMDIDYMNGYRVFT
FDDKKFPDVKGLSEKLADRGVKLISIIDPGVKKDEDYFMYKEGMEMDAFAHDTDGSVYENAVWPGTSVFPDFTKQSVRSW
WGDKTKILLEHGISGIWNDMNEPASFNGPLPDDVQFEYGAHEKVHNIYGHFMAKATYEGLAKNDGGKRPFVLTRAAYAGS
QKYCGGWTGDNHSIWAHIALSLEQVCNLSVSGLAMCGSDIGGFGSDTTPELLVRFYEAAVFVPFFRNHSAMGTRRQEPWQ
FDETTIDAVRKTVKLRYRFIPYIYDLAHECEKTGAPIVRPLVYEYHADKHVRNISDEYMLGSFVLVAPVIAPGKEAREVY
LPDGDWYDYYTGEKYSGGRYILADAPLDKVPVFIKAGAIIPVADGEIRSTEDITEDKISILTYPGKGSFVHYQDDNETFA
YRNGAYNAVEYTLDGDKLEKKVLHKGL

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI38202257, Length=786, Percent_Identity=30.4071246819338, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI88900491, Length=564, Percent_Identity=35.9929078014184, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI66346737, Length=770, Percent_Identity=30.7792207792208, Blast_Score=355, Evalue=9e-98,
Organism=Homo sapiens, GI119393895, Length=642, Percent_Identity=29.2834890965732, Blast_Score=280, Evalue=3e-75,
Organism=Homo sapiens, GI119393893, Length=642, Percent_Identity=29.2834890965732, Blast_Score=280, Evalue=3e-75,
Organism=Homo sapiens, GI119393891, Length=642, Percent_Identity=29.2834890965732, Blast_Score=280, Evalue=3e-75,
Organism=Homo sapiens, GI221316699, Length=567, Percent_Identity=30.5114638447972, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI157364974, Length=681, Percent_Identity=28.4875183553598, Blast_Score=263, Evalue=6e-70,
Organism=Homo sapiens, GI310115361, Length=482, Percent_Identity=29.6680497925311, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI153791946, Length=417, Percent_Identity=26.378896882494, Blast_Score=122, Evalue=2e-27,
Organism=Escherichia coli, GI2367256, Length=541, Percent_Identity=26.8022181146026, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI2367323, Length=561, Percent_Identity=26.5597147950089, Blast_Score=150, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71991189, Length=524, Percent_Identity=36.4503816793893, Blast_Score=345, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17560800, Length=512, Percent_Identity=35.3515625, Blast_Score=342, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI17560798, Length=512, Percent_Identity=35.3515625, Blast_Score=342, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI71985706, Length=570, Percent_Identity=27.1929824561404, Blast_Score=215, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI32563849, Length=567, Percent_Identity=28.2186948853616, Blast_Score=209, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6319706, Length=611, Percent_Identity=32.2422258592471, Blast_Score=296, Evalue=8e-81,
Organism=Drosophila melanogaster, GI24643749, Length=590, Percent_Identity=33.5593220338983, Blast_Score=352, Evalue=5e-97,
Organism=Drosophila melanogaster, GI24643753, Length=590, Percent_Identity=33.5593220338983, Blast_Score=352, Evalue=5e-97,
Organism=Drosophila melanogaster, GI24643751, Length=590, Percent_Identity=33.5593220338983, Blast_Score=352, Evalue=5e-97,
Organism=Drosophila melanogaster, GI24643746, Length=590, Percent_Identity=33.5593220338983, Blast_Score=352, Evalue=5e-97,
Organism=Drosophila melanogaster, GI21357605, Length=590, Percent_Identity=33.5593220338983, Blast_Score=352, Evalue=5e-97,
Organism=Drosophila melanogaster, GI24650054, Length=429, Percent_Identity=26.3403263403263, Blast_Score=117, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 84357; Mature: 84226

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00129 GLYCOSYL_HYDROL_F31_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNLYKNCKIQDNTAELIYENGSLFVTIFENNIVHVAQKHGIESVAIEEDFIPKAATPDV
CCCCCCCCEEECCCEEEEEECCCEEEEEECCCEEEEHHHCCCCEEEECCCCCCCCCCCCC
TCKDTSDAKGTAAEAGVSDAAVKAVISARDITVNVKDNEKLDIYYKGKLVLSDYETARKK
EECCCCCCCCCHHHCCCCHHHHHHHEEEEEEEEEECCCCEEEEEEECEEEECCCHHHHHH
SEKNPYEDLAIAELEGHTVGKDEEKTDAVTIIKKLGKDDAIYGLGDKPGCLNKRGYSYVN
CCCCCCHHEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEE
WNTDDPAPHVDSFKSLYKSIPFFIVLGDEYCYGIFADNTYKTTFDFGYENTDYYFVEHEK
CCCCCCCCCHHHHHHHHHCCCEEEEECCCEEEEEEECCEEEEEEECCCCCCEEEEEEECC
GELDYYFMPGNDMAEVVGLYTSLTGTTPLYQRWIYGSHQSRWGYYTQDEVLDIADKFREL
CCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
DIPCDVIHMDIDYMNGYRVFTFDDKKFPDVKGLSEKLADRGVKLISIIDPGVKKDEDYFM
CCCEEEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCEEE
YKEGMEMDAFAHDTDGSVYENAVWPGTSVFPDFTKQSVRSWWGDKTKILLEHGISGIWND
EECCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEHHCCCHHHHC
MNEPASFNGPLPDDVQFEYGAHEKVHNIYGHFMAKATYEGLAKNDGGKRPFVLTRAAYAG
CCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCC
SQKYCGGWTGDNHSIWAHIALSLEQVCNLSVSGLAMCGSDIGGFGSDTTPELLVRFYEAA
CCCCCCCCCCCCCCEEEEEHEEHHHHHCCCCCHHEECCCCCCCCCCCCCHHHHHHHHHHH
VFVPFFRNHSAMGTRRQEPWQFDETTIDAVRKTVKLRYRFIPYIYDLAHECEKTGAPIVR
EEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
PLVYEYHADKHVRNISDEYMLGSFVLVAPVIAPGKEAREVYLPDGDWYDYYTGEKYSGGR
HHHHHHHCCHHHHCCCCHHHHHHHHEEHHEECCCCCCCEEECCCCCEECCCCCCEECCCE
YILADAPLDKVPVFIKAGAIIPVADGEIRSTEDITEDKISILTYPGKGSFVHYQDDNETF
EEEECCCCCCCCEEEECCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCEE
AYRNGAYNAVEYTLDGDKLEKKVLHKGL
EEECCCCCEEEEEECHHHHHHHHHHCCC
>Mature Secondary Structure 
GNLYKNCKIQDNTAELIYENGSLFVTIFENNIVHVAQKHGIESVAIEEDFIPKAATPDV
CCCCCCCEEECCCEEEEEECCCEEEEEECCCEEEEHHHCCCCEEEECCCCCCCCCCCCC
TCKDTSDAKGTAAEAGVSDAAVKAVISARDITVNVKDNEKLDIYYKGKLVLSDYETARKK
EECCCCCCCCCHHHCCCCHHHHHHHEEEEEEEEEECCCCEEEEEEECEEEECCCHHHHHH
SEKNPYEDLAIAELEGHTVGKDEEKTDAVTIIKKLGKDDAIYGLGDKPGCLNKRGYSYVN
CCCCCCHHEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEE
WNTDDPAPHVDSFKSLYKSIPFFIVLGDEYCYGIFADNTYKTTFDFGYENTDYYFVEHEK
CCCCCCCCCHHHHHHHHHCCCEEEEECCCEEEEEEECCEEEEEEECCCCCCEEEEEEECC
GELDYYFMPGNDMAEVVGLYTSLTGTTPLYQRWIYGSHQSRWGYYTQDEVLDIADKFREL
CCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
DIPCDVIHMDIDYMNGYRVFTFDDKKFPDVKGLSEKLADRGVKLISIIDPGVKKDEDYFM
CCCEEEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCEEE
YKEGMEMDAFAHDTDGSVYENAVWPGTSVFPDFTKQSVRSWWGDKTKILLEHGISGIWND
EECCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEHHCCCHHHHC
MNEPASFNGPLPDDVQFEYGAHEKVHNIYGHFMAKATYEGLAKNDGGKRPFVLTRAAYAG
CCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCC
SQKYCGGWTGDNHSIWAHIALSLEQVCNLSVSGLAMCGSDIGGFGSDTTPELLVRFYEAA
CCCCCCCCCCCCCCEEEEEHEEHHHHHCCCCCHHEECCCCCCCCCCCCCHHHHHHHHHHH
VFVPFFRNHSAMGTRRQEPWQFDETTIDAVRKTVKLRYRFIPYIYDLAHECEKTGAPIVR
EEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
PLVYEYHADKHVRNISDEYMLGSFVLVAPVIAPGKEAREVYLPDGDWYDYYTGEKYSGGR
HHHHHHHCCHHHHCCCCHHHHHHHHEEHHEECCCCCCCEEECCCCCEECCCCCCEECCCE
YILADAPLDKVPVFIKAGAIIPVADGEIRSTEDITEDKISILTYPGKGSFVHYQDDNETF
EEEECCCCCCCCEEEECCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCEE
AYRNGAYNAVEYTLDGDKLEKKVLHKGL
EEECCCCCEEEEEECHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]