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The map label for this gene is malE [C]

Identifier: 238922908

GI number: 238922908

Start: 457874

End: 459235

Strand: Direct

Name: malE [C]

Synonym: EUBREC_0496

Alternate gene names: 238922908

Gene position: 457874-459235 (Clockwise)

Preceding gene: 238922906

Following gene: 238922909

Centisome position: 13.27

GC content: 42.07

Gene sequence:

>1362_bases
ATGAAGAAGAAACTTATTGCAACAGTTATGGCAGCTACAATGGCAGTGACAGCGCTTACAGGCTGTGGCAGCTCATCGGC
TTCATCAGCTAAAAAGGACATAAAGGTACCAACAAAGCCATTTGGCGATACGGTGAAGTATGACCCTTCGGTTGAGATTA
ATGATGGAAAGGATATCTCAATTGACCTGTGGGAGTGGGGAAGCGATGAATTATTTCAGAAGGTTATTGACAGATACACA
GCTATTCATCCTAATGTAACTATAAACCTGGTGGATAATCCATGGGAAGATTACTGGACAAAGCTTCCTCTGGCACTCGA
TGGTGAGGACGGACCGGCACTCTTCGATGTACATAACAGCTATCATGAGAATCTTATCAACTATATGGCTCCGCTTGATA
TTCCTGTTGAGGATTTGGAGCAGGACTTCAATGGAGTGAGCGCTCATGTGATTGATGGTAAGGTTTATTACATTGATTAC
GGAATGATGACAGGCTCTGTTTATTACAACAAGGAGATGTGGAAGGAAGCCGGACTAACAGATGATGATATTCCAAAGAC
CTGGGATGAAATGATTGAGGTGGCAAAGAAGCTTACCATCAAGGACGGAGACAAGATAGTCCAGGCCGGACTCAATTTCA
ATAATGATTTCCACCAGAATTACCTGCTTGGTCTTAATTATCAGCTTGGTGAGAACCTCTTTAAGGAGGATGGAAAGACA
CCTAATGTCAATTCAGATGCCATGAAGAAGGTAATGCAGATGCTTGTTGATATGTACGACAAGGATCAGATTGGTTCAAA
GGATTTTGGCGAGAACTGCGCAGACAGCTTTGGACAGGGACAGTCGGCAATGGTTATTCAGTGGGGACATTATTACAATA
CACTTAAGACCACATGGAGCGATATAGATTTTGGCGTATTTGAAATTCCTACATTTGACGGAAATCCATATGCATACAAT
AGATATAACGGTGAGTCAACATTCGGTGTAAACAAAAAAGCACCAAAGGATCAGCAGGCAGTTGCACAGGATTTTGTAAA
GTTTTTCCTCTGCGATGATGAGTCTCAGGTAGATTTCAATCTTGCTATGAGTACCTTCCCTGCAAAGAAATCCCTTGCAG
ACAATGAGGAAATACTTAAAAACCCATCGCTTAAGGTACTTGCAGAGCACATTGACCACTACATCTGGCCGGGTCCGATG
CCTTCATGTGTTGAGGAGGATATGAAAAAGGCCGGAGAGGATATATTCTACAATGGAGTAGATATTGATACGGCTTTAGA
CAAGGCACAGGCTGATATTATAAAGGATATGAAGAGCAGTTCATTCCAATCAGTCGAGAATCTATATGAGTTTGCAAAAT
AA

Upstream 100 bases:

>100_bases
ATTGACGAATGTATAAGGTGGTGGTAGATTATAGTTAGATTTAGCGCTAAACTAATTTGAACGAAAAAGAGGATATTGAA
TTAAGAAAGTGAGGATTTCT

Downstream 100 bases:

>100_bases
CATGTAGAGATTCACTACGGAGGATTATTAATGTTTAAAAAATCACATCCATTACAAAGTAAGAGTGAAATAATTTTAAG
AAACATAGTTGTTGTAGCTA

Product: secreted sugar binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: Sugar ABC Transporter Periplasmic Component; Sugar ABC Transporter Periplasmic Component-Like Protein; Maltose/Maltodextrin Transport Permease Homologue; Male-Type Abc Sugar Transport System Periplasmic Component; Transcriptional Regulator; ABC-Type Transport System Periplasmic Component; Sugar ABC Transporter Periplasmic Protein; Sn-Glycerol-3-Phosphate Transport System; Sugar ABC Transporter; ABC-Type Sugar Transport System

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MKKKLIATVMAATMAVTALTGCGSSSASSAKKDIKVPTKPFGDTVKYDPSVEINDGKDISIDLWEWGSDELFQKVIDRYT
AIHPNVTINLVDNPWEDYWTKLPLALDGEDGPALFDVHNSYHENLINYMAPLDIPVEDLEQDFNGVSAHVIDGKVYYIDY
GMMTGSVYYNKEMWKEAGLTDDDIPKTWDEMIEVAKKLTIKDGDKIVQAGLNFNNDFHQNYLLGLNYQLGENLFKEDGKT
PNVNSDAMKKVMQMLVDMYDKDQIGSKDFGENCADSFGQGQSAMVIQWGHYYNTLKTTWSDIDFGVFEIPTFDGNPYAYN
RYNGESTFGVNKKAPKDQQAVAQDFVKFFLCDDESQVDFNLAMSTFPAKKSLADNEEILKNPSLKVLAEHIDHYIWPGPM
PSCVEEDMKKAGEDIFYNGVDIDTALDKAQADIIKDMKSSSFQSVENLYEFAK

Sequences:

>Translated_453_residues
MKKKLIATVMAATMAVTALTGCGSSSASSAKKDIKVPTKPFGDTVKYDPSVEINDGKDISIDLWEWGSDELFQKVIDRYT
AIHPNVTINLVDNPWEDYWTKLPLALDGEDGPALFDVHNSYHENLINYMAPLDIPVEDLEQDFNGVSAHVIDGKVYYIDY
GMMTGSVYYNKEMWKEAGLTDDDIPKTWDEMIEVAKKLTIKDGDKIVQAGLNFNNDFHQNYLLGLNYQLGENLFKEDGKT
PNVNSDAMKKVMQMLVDMYDKDQIGSKDFGENCADSFGQGQSAMVIQWGHYYNTLKTTWSDIDFGVFEIPTFDGNPYAYN
RYNGESTFGVNKKAPKDQQAVAQDFVKFFLCDDESQVDFNLAMSTFPAKKSLADNEEILKNPSLKVLAEHIDHYIWPGPM
PSCVEEDMKKAGEDIFYNGVDIDTALDKAQADIIKDMKSSSFQSVENLYEFAK
>Mature_453_residues
MKKKLIATVMAATMAVTALTGCGSSSASSAKKDIKVPTKPFGDTVKYDPSVEINDGKDISIDLWEWGSDELFQKVIDRYT
AIHPNVTINLVDNPWEDYWTKLPLALDGEDGPALFDVHNSYHENLINYMAPLDIPVEDLEQDFNGVSAHVIDGKVYYIDY
GMMTGSVYYNKEMWKEAGLTDDDIPKTWDEMIEVAKKLTIKDGDKIVQAGLNFNNDFHQNYLLGLNYQLGENLFKEDGKT
PNVNSDAMKKVMQMLVDMYDKDQIGSKDFGENCADSFGQGQSAMVIQWGHYYNTLKTTWSDIDFGVFEIPTFDGNPYAYN
RYNGESTFGVNKKAPKDQQAVAQDFVKFFLCDDESQVDFNLAMSTFPAKKSLADNEEILKNPSLKVLAEHIDHYIWPGPM
PSCVEEDMKKAGEDIFYNGVDIDTALDKAQADIIKDMKSSSFQSVENLYEFAK

Specific function: Involved In The High-Affinity Maltose Membrane Transport System Malefgk. Initial Receptor For The Active Transport Of And Chemotaxis Toward Maltooligosaccharides. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51048; Mature: 51048

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLIATVMAATMAVTALTGCGSSSASSAKKDIKVPTKPFGDTVKYDPSVEINDGKDIS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCEECCCCEEECCCCEEE
IDLWEWGSDELFQKVIDRYTAIHPNVTINLVDNPWEDYWTKLPLALDGEDGPALFDVHNS
EEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCEEECCCCCCEEEECHHH
YHENLINYMAPLDIPVEDLEQDFNGVSAHVIDGKVYYIDYGMMTGSVYYNKEMWKEAGLT
HHHHHHHHHCCCCCCHHHHHHHCCCCEEEEECCEEEEEEECEEECEEEECHHHHHHCCCC
DDDIPKTWDEMIEVAKKLTIKDGDKIVQAGLNFNNDFHQNYLLGLNYQLGENLFKEDGKT
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHCCCC
PNVNSDAMKKVMQMLVDMYDKDQIGSKDFGENCADSFGQGQSAMVIQWGHYYNTLKTTWS
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHHC
DIDFGVFEIPTFDGNPYAYNRYNGESTFGVNKKAPKDQQAVAQDFVKFFLCDDESQVDFN
CCCCCEEEECCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCEEE
LAMSTFPAKKSLADNEEILKNPSLKVLAEHIDHYIWPGPMPSCVEEDMKKAGEDIFYNGV
EEECCCCCHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEECCC
DIDTALDKAQADIIKDMKSSSFQSVENLYEFAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKKLIATVMAATMAVTALTGCGSSSASSAKKDIKVPTKPFGDTVKYDPSVEINDGKDIS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCEECCCCEEECCCCEEE
IDLWEWGSDELFQKVIDRYTAIHPNVTINLVDNPWEDYWTKLPLALDGEDGPALFDVHNS
EEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCEEECCCCCCEEEECHHH
YHENLINYMAPLDIPVEDLEQDFNGVSAHVIDGKVYYIDYGMMTGSVYYNKEMWKEAGLT
HHHHHHHHHCCCCCCHHHHHHHCCCCEEEEECCEEEEEEECEEECEEEECHHHHHHCCCC
DDDIPKTWDEMIEVAKKLTIKDGDKIVQAGLNFNNDFHQNYLLGLNYQLGENLFKEDGKT
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHCCCC
PNVNSDAMKKVMQMLVDMYDKDQIGSKDFGENCADSFGQGQSAMVIQWGHYYNTLKTTWS
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHHC
DIDFGVFEIPTFDGNPYAYNRYNGESTFGVNKKAPKDQQAVAQDFVKFFLCDDESQVDFN
CCCCCEEEECCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCEEE
LAMSTFPAKKSLADNEEILKNPSLKVLAEHIDHYIWPGPMPSCVEEDMKKAGEDIFYNGV
EEECCCCCHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEECCC
DIDTALDKAQADIIKDMKSSSFQSVENLYEFAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA