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The map label for this gene is mglC [H]

Identifier: 238922891

GI number: 238922891

Start: 436379

End: 438028

Strand: Direct

Name: mglC [H]

Synonym: EUBREC_0479

Alternate gene names: 238922891

Gene position: 436379-438028 (Clockwise)

Preceding gene: 238922890

Following gene: 238922892

Centisome position: 12.65

GC content: 41.88

Gene sequence:

>1650_bases
ATGGCTAATAGTAAGATTTTAACGGCTGAGCAGGAGCGTGCTCTGCGCCAGCCTATCGACGAATATGTTGGTGGAATACA
AAAAGAAATTGATGCACTCAGAAAAGACGGAACTACAAAGGTTGTAGAGTGTCAGTCAGCGATAGCAGGCATCAAGAGAG
ATAAAACTCTTTCAAAGGGCGAGAAAGAGTCAGAAATAGCAGCCTGCGAGAAAGAGCTTGCAAAGGCAAAGGCTGTTGAG
GCAAAGAACAAGGATGAGATTTCAAAGCTCATTGCCAAGGCTGAAAGCTATTTAAAGGAAAATTTTGATTCAAAGTATTA
CAATGCCGTTAAGGCAAGCTGTGAGGCGGAAAAGGCAGAGGCGCTTGCTGCTCATAATGAGAGAATGGCAGAGCTTGATA
AAAAGCACAAGGCTGCTCTTGCAAAGACATCAGACAGTACTGAGATAAAGGAAGAAAACTACGTACACAAGAATCGTATT
TCCAATGAGAAGCTTGAGCTCGAGAAAGAGTATCAGACGATCAAGGACAAAAAGCATGAGGCATACAGCTACAAGTATCA
CCTGATTGATATGCTTCGTCTTTCAAAGTTCACATTTATGGAGAAAAGAGCTCAGAAATGGGAGAATTACAAGTATACGT
TCAATAGGAGAAACTTCCTGTTACAGAATGGTCTTTATATTGCAATTATACTTATATTCATAGCGCTTTGTGTCATAACA
CCGATAAAGAAGGGCACACCTCTTCTGACATACAACAACATACTGAATATTCTTCAGCAGGCTTCACCGAGAATGTTCTT
AGCACTTGGTGTTGCAGGACTTATCCTCTTAACAGGAACGGACCTTTCTGTTGGACGAATGGTTGGTATGGGTATGACAA
CAGCCACAATCATCATGCATCAGGGTATTAATACAGGTTCTGTATTCGGTCATATATTTGACTTTACAGGAGTACCAACA
GGTGCAAGAGTGGTTATCGCATTACTTGCATGTATCGTGCTTTGTACATTCTTCACAAGTATTGCAGGATTTTTTACAGC
GAAGTTTAAGATGCATCCGTTTATTTCAACCATGGCCAACATGCTTGTTATCTTCGGTATCGTAACATATGCTACAAAGG
GAGTTTCATTCGGTGCTATTGAGCCGGTTATTCCTAACATGATTATTCCAAAGTTAAATGGTTTCCCAACCATCATCCTC
TGGGCAGTAGCAGCAATCGCAATTGTATGGTTTATCTGGAACAAGACAACATTTGGTAAAAACCTCTACGCAGTAGGAGG
AAACCCGGAGGCAGCAGCAGTTTCAGGTATCTCAGTATTTGCAGTAACTCTCGGCGCATTCGTGATGGCCGGTATCCTTT
ATGGATTTGGCTCATGGCTTGAGTGTGCAAGAATGGTTGGTTCAGGTTCAGCAGCTTATGGACAGGGCTGGGATATGGAC
GCAATCGCAGCCTGTGTAGTTGGTGGTGTATCATTCACAGGTGGTATCGGTAAGATATCAGGTGTTGTAACCGGTGTATG
TATCTTCACAGCACTCACATACTCTCTTACAATCCTTGGTATTGATACAAACCTTCAGTTCGTATTCTCAGGAATTATCA
TTCTTGTAGCAGTTACACTTGACTGTCTGAAATACGTTCAGAAGAAATAA

Upstream 100 bases:

>100_bases
AAACGGACGACTCTCAGGAATTGTCAATACAAAGGAAACCAATCAGGAAGAACTGCTGAGACTCAGTGCAAAGTACCTAT
AATAAAGGGAGAAGACGGAT

Downstream 100 bases:

>100_bases
TATCGCAAGAAAATTTCTTTTTCATACTTCCAAAATGATCAGCAGAGATGTCAGGGTGGCATCTCTGCTTTAATTTTGTT
GTGTGGACAGTTATACTTTT

Product: galactoside ABC transporter, permease protein, putative

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MANSKILTAEQERALRQPIDEYVGGIQKEIDALRKDGTTKVVECQSAIAGIKRDKTLSKGEKESEIAACEKELAKAKAVE
AKNKDEISKLIAKAESYLKENFDSKYYNAVKASCEAEKAEALAAHNERMAELDKKHKAALAKTSDSTEIKEENYVHKNRI
SNEKLELEKEYQTIKDKKHEAYSYKYHLIDMLRLSKFTFMEKRAQKWENYKYTFNRRNFLLQNGLYIAIILIFIALCVIT
PIKKGTPLLTYNNILNILQQASPRMFLALGVAGLILLTGTDLSVGRMVGMGMTTATIIMHQGINTGSVFGHIFDFTGVPT
GARVVIALLACIVLCTFFTSIAGFFTAKFKMHPFISTMANMLVIFGIVTYATKGVSFGAIEPVIPNMIIPKLNGFPTIIL
WAVAAIAIVWFIWNKTTFGKNLYAVGGNPEAAAVSGISVFAVTLGAFVMAGILYGFGSWLECARMVGSGSAAYGQGWDMD
AIAACVVGGVSFTGGIGKISGVVTGVCIFTALTYSLTILGIDTNLQFVFSGIIILVAVTLDCLKYVQKK

Sequences:

>Translated_549_residues
MANSKILTAEQERALRQPIDEYVGGIQKEIDALRKDGTTKVVECQSAIAGIKRDKTLSKGEKESEIAACEKELAKAKAVE
AKNKDEISKLIAKAESYLKENFDSKYYNAVKASCEAEKAEALAAHNERMAELDKKHKAALAKTSDSTEIKEENYVHKNRI
SNEKLELEKEYQTIKDKKHEAYSYKYHLIDMLRLSKFTFMEKRAQKWENYKYTFNRRNFLLQNGLYIAIILIFIALCVIT
PIKKGTPLLTYNNILNILQQASPRMFLALGVAGLILLTGTDLSVGRMVGMGMTTATIIMHQGINTGSVFGHIFDFTGVPT
GARVVIALLACIVLCTFFTSIAGFFTAKFKMHPFISTMANMLVIFGIVTYATKGVSFGAIEPVIPNMIIPKLNGFPTIIL
WAVAAIAIVWFIWNKTTFGKNLYAVGGNPEAAAVSGISVFAVTLGAFVMAGILYGFGSWLECARMVGSGSAAYGQGWDMD
AIAACVVGGVSFTGGIGKISGVVTGVCIFTALTYSLTILGIDTNLQFVFSGIIILVAVTLDCLKYVQKK
>Mature_548_residues
ANSKILTAEQERALRQPIDEYVGGIQKEIDALRKDGTTKVVECQSAIAGIKRDKTLSKGEKESEIAACEKELAKAKAVEA
KNKDEISKLIAKAESYLKENFDSKYYNAVKASCEAEKAEALAAHNERMAELDKKHKAALAKTSDSTEIKEENYVHKNRIS
NEKLELEKEYQTIKDKKHEAYSYKYHLIDMLRLSKFTFMEKRAQKWENYKYTFNRRNFLLQNGLYIAIILIFIALCVITP
IKKGTPLLTYNNILNILQQASPRMFLALGVAGLILLTGTDLSVGRMVGMGMTTATIIMHQGINTGSVFGHIFDFTGVPTG
ARVVIALLACIVLCTFFTSIAGFFTAKFKMHPFISTMANMLVIFGIVTYATKGVSFGAIEPVIPNMIIPKLNGFPTIILW
AVAAIAIVWFIWNKTTFGKNLYAVGGNPEAAAVSGISVFAVTLGAFVMAGILYGFGSWLECARMVGSGSAAYGQGWDMDA
IAACVVGGVSFTGGIGKISGVVTGVCIFTALTYSLTILGIDTNLQFVFSGIIILVAVTLDCLKYVQKK

Specific function: Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4211

COG function: function code G; ABC-type glucose/galactose transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788471, Length=360, Percent_Identity=38.0555555555556, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1790191, Length=335, Percent_Identity=29.5522388059701, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI145693152, Length=206, Percent_Identity=35.9223300970874, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790524, Length=297, Percent_Identity=29.96632996633, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788896, Length=204, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789992, Length=132, Percent_Identity=37.8787878787879, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI87082395, Length=267, Percent_Identity=28.4644194756554, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 60065; Mature: 59934

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSKILTAEQERALRQPIDEYVGGIQKEIDALRKDGTTKVVECQSAIAGIKRDKTLSKG
CCCCCEECHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
EKESEIAACEKELAKAKAVEAKNKDEISKLIAKAESYLKENFDSKYYNAVKASCEAEKAE
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ALAAHNERMAELDKKHKAALAKTSDSTEIKEENYVHKNRISNEKLELEKEYQTIKDKKHE
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHHHCCCCHHHHHHHHHHHHHHCCCH
AYSYKYHLIDMLRLSKFTFMEKRAQKWENYKYTFNRRNFLLQNGLYIAIILIFIALCVIT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHCCHHHHHHHHHHHHHHHC
PIKKGTPLLTYNNILNILQQASPRMFLALGVAGLILLTGTDLSVGRMVGMGMTTATIIMH
CCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCHHHHHHHCCHHHHHHHHH
QGINTGSVFGHIFDFTGVPTGARVVIALLACIVLCTFFTSIAGFFTAKFKMHPFISTMAN
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
MLVIFGIVTYATKGVSFGAIEPVIPNMIIPKLNGFPTIILWAVAAIAIVWFIWNKTTFGK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
NLYAVGGNPEAAAVSGISVFAVTLGAFVMAGILYGFGSWLECARMVGSGSAAYGQGWDMD
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
AIAACVVGGVSFTGGIGKISGVVTGVCIFTALTYSLTILGIDTNLQFVFSGIIILVAVTL
HHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHH
DCLKYVQKK
HHHHHHHCC
>Mature Secondary Structure 
ANSKILTAEQERALRQPIDEYVGGIQKEIDALRKDGTTKVVECQSAIAGIKRDKTLSKG
CCCCEECHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
EKESEIAACEKELAKAKAVEAKNKDEISKLIAKAESYLKENFDSKYYNAVKASCEAEKAE
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ALAAHNERMAELDKKHKAALAKTSDSTEIKEENYVHKNRISNEKLELEKEYQTIKDKKHE
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHHHCCCCHHHHHHHHHHHHHHCCCH
AYSYKYHLIDMLRLSKFTFMEKRAQKWENYKYTFNRRNFLLQNGLYIAIILIFIALCVIT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHCCHHHHHHHHHHHHHHHC
PIKKGTPLLTYNNILNILQQASPRMFLALGVAGLILLTGTDLSVGRMVGMGMTTATIIMH
CCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCHHHHHHHCCHHHHHHHHH
QGINTGSVFGHIFDFTGVPTGARVVIALLACIVLCTFFTSIAGFFTAKFKMHPFISTMAN
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
MLVIFGIVTYATKGVSFGAIEPVIPNMIIPKLNGFPTIILWAVAAIAIVWFIWNKTTFGK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
NLYAVGGNPEAAAVSGISVFAVTLGAFVMAGILYGFGSWLECARMVGSGSAAYGQGWDMD
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
AIAACVVGGVSFTGGIGKISGVVTGVCIFTALTYSLTILGIDTNLQFVFSGIIILVAVTL
HHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHH
DCLKYVQKK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8921855; 8988365; 9665876 [H]