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The map label for this gene is map [H]

Identifier: 238922851

GI number: 238922851

Start: 395016

End: 395810

Strand: Direct

Name: map [H]

Synonym: EUBREC_0439

Alternate gene names: 238922851

Gene position: 395016-395810 (Clockwise)

Preceding gene: 238922850

Following gene: 238922852

Centisome position: 11.45

GC content: 46.54

Gene sequence:

>795_bases
ATGTCTGTAACTATAAAATCAGAGCATGAGATAGAGCTGATGAGGGAGGCCGGCAGGATTCTGGCGGCCGTTCATCAGCA
GCTCGGTAAAGAAATCAAACCGGGAATGTCCACTAAGGATGTGGACCGGCTGGGCGAAGAAATGATTCGTAGTTATGGAT
GCGAGCCGTCTTTCTTAGGATATTGCGGATATCCGGCCTCCATATGTGTTTCAGTAAATGAGGAGGTTGTACATGGTATC
CCGACTGATGAGCGTATCTTACAGGAGGGCGATATCGTGAGCCTTGATGCTGGTGTTATCTACAAAGGATACCACTCAGA
CGCAGCCAGAACAGTAGGCGTAGGAGAGATTTCAGAGGAAGCAAGACTTCTTATAGAAAGAACACGTCTCAGTTTTTTTG
CAGGAATAAAGAATGCAGTTGCGGGAAACAGACTGTATGATATTTCAGGAGCCATACAGCAGCTTGCCGAGTCTTTTGGA
TACGGAGTTGTATATGACCTTGTTGGTCATGGCATAGGAAGCCATTTACATGAGGATCCTGAGGTGCCGAACTTCAGACC
ACAGGGCTTTAGAAAAGGGCTCAGACTTAAGCCGGGCATGACACTGGCGGTTGAGCCAATGATTAATGCAGGTTCACCGC
ATGTGGTGTGGATGGATGACGAATGGACAGTGGTTACTGAGGATTTATCGTTGTCGGCACACTATGAAAATACCATACTT
ATTACAAAAGGAAAGCCGGAGATACTTTCTCTGACAGAGGATGAAAAAGCAGCCGGATTTCTGGAGCTAATCTAA

Upstream 100 bases:

>100_bases
TCGAGTATTATGACAAGCAGGGCATTTTAAAGTCTGTAGACGGAACAAAGCCTATGGATGAAGTTTTTTCAGCCATTGTA
GGTATTTTAGGTGAATAATA

Downstream 100 bases:

>100_bases
TAATAATCATAACGAAACCCAAGGATTTATTTACAGGAGGAATCAAAATGTCAAAAGCAGACGTTATCGAAGTTGAAGGT
GTTGTAGTTGAGAAGTTACC

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSVTIKSEHEIELMREAGRILAAVHQQLGKEIKPGMSTKDVDRLGEEMIRSYGCEPSFLGYCGYPASICVSVNEEVVHGI
PTDERILQEGDIVSLDAGVIYKGYHSDAARTVGVGEISEEARLLIERTRLSFFAGIKNAVAGNRLYDISGAIQQLAESFG
YGVVYDLVGHGIGSHLHEDPEVPNFRPQGFRKGLRLKPGMTLAVEPMINAGSPHVVWMDDEWTVVTEDLSLSAHYENTIL
ITKGKPEILSLTEDEKAAGFLELI

Sequences:

>Translated_264_residues
MSVTIKSEHEIELMREAGRILAAVHQQLGKEIKPGMSTKDVDRLGEEMIRSYGCEPSFLGYCGYPASICVSVNEEVVHGI
PTDERILQEGDIVSLDAGVIYKGYHSDAARTVGVGEISEEARLLIERTRLSFFAGIKNAVAGNRLYDISGAIQQLAESFG
YGVVYDLVGHGIGSHLHEDPEVPNFRPQGFRKGLRLKPGMTLAVEPMINAGSPHVVWMDDEWTVVTEDLSLSAHYENTIL
ITKGKPEILSLTEDEKAAGFLELI
>Mature_263_residues
SVTIKSEHEIELMREAGRILAAVHQQLGKEIKPGMSTKDVDRLGEEMIRSYGCEPSFLGYCGYPASICVSVNEEVVHGIP
TDERILQEGDIVSLDAGVIYKGYHSDAARTVGVGEISEEARLLIERTRLSFFAGIKNAVAGNRLYDISGAIQQLAESFGY
GVVYDLVGHGIGSHLHEDPEVPNFRPQGFRKGLRLKPGMTLAVEPMINAGSPHVVWMDDEWTVVTEDLSLSAHYENTILI
TKGKPEILSLTEDEKAAGFLELI

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=37.3493975903614, Blast_Score=164, Evalue=7e-41,
Organism=Homo sapiens, GI164420681, Length=263, Percent_Identity=36.1216730038023, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1786364, Length=262, Percent_Identity=39.6946564885496, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1788728, Length=210, Percent_Identity=31.4285714285714, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71996291, Length=267, Percent_Identity=34.8314606741573, Blast_Score=150, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6323273, Length=265, Percent_Identity=34.7169811320755, Blast_Score=155, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24583427, Length=249, Percent_Identity=34.9397590361446, Blast_Score=157, Evalue=8e-39,
Organism=Drosophila melanogaster, GI21355531, Length=248, Percent_Identity=35.4838709677419, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI19920384, Length=234, Percent_Identity=25.2136752136752, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 28969; Mature: 28838

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTIKSEHEIELMREAGRILAAVHQQLGKEIKPGMSTKDVDRLGEEMIRSYGCEPSFLG
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEE
YCGYPASICVSVNEEVVHGIPTDERILQEGDIVSLDAGVIYKGYHSDAARTVGVGEISEE
ECCCCCEEEEECCHHHHCCCCCHHHHHHCCCEEEECCCEEEECCCCCCHHCCCCCHHHHH
ARLLIERTRLSFFAGIKNAVAGNRLYDISGAIQQLAESFGYGVVYDLVGHGIGSHLHEDP
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCCC
EVPNFRPQGFRKGLRLKPGMTLAVEPMINAGSPHVVWMDDEWTVVTEDLSLSAHYENTIL
CCCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCEEEEECCCCEEEEECCEEEEECCCEEE
ITKGKPEILSLTEDEKAAGFLELI
EECCCCCEEEECCCCHHCCHHHCC
>Mature Secondary Structure 
SVTIKSEHEIELMREAGRILAAVHQQLGKEIKPGMSTKDVDRLGEEMIRSYGCEPSFLG
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEE
YCGYPASICVSVNEEVVHGIPTDERILQEGDIVSLDAGVIYKGYHSDAARTVGVGEISEE
ECCCCCEEEEECCHHHHCCCCCHHHHHHCCCEEEECCCEEEECCCCCCHHCCCCCHHHHH
ARLLIERTRLSFFAGIKNAVAGNRLYDISGAIQQLAESFGYGVVYDLVGHGIGSHLHEDP
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCCC
EVPNFRPQGFRKGLRLKPGMTLAVEPMINAGSPHVVWMDDEWTVVTEDLSLSAHYENTIL
CCCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCEEEEECCCCEEEEECCEEEEECCCEEE
ITKGKPEILSLTEDEKAAGFLELI
EECCCCCEEEECCCCHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]