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The map label for this gene is tadA [H]

Identifier: 238922727

GI number: 238922727

Start: 281463

End: 281951

Strand: Direct

Name: tadA [H]

Synonym: EUBREC_0302

Alternate gene names: 238922727

Gene position: 281463-281951 (Clockwise)

Preceding gene: 238922726

Following gene: 238922728

Centisome position: 8.16

GC content: 47.24

Gene sequence:

>489_bases
ATGGAGCAGACAAATATGACACAAGATGAAAAATATATGAAACAGGCAATAAAACAGGCAAAAAAAGCATATGCACTTGA
TGAGGTGCCGATAGGCTGCGTAATTGTAGCCGGTGACAAAATCATCGCACGCGGTTACAACCGCAGAAATACCGACAAAA
ATCCACTCGCTCACGCTGAGCTTTCTGCCATCCGTAAAGCCAGCAAAAAGACCGGAGATTGGCGTCTTGAGGAATGCACC
ATGTATGTCACCCTTGAGCCCTGTCAGATGTGTGCCGGAGCAATAGTACAGGCACGCATTCCCAGGGTGGTAATAGGTGC
CATGAATCCGAAAGCAGGCTGTGCAGGCTCAATCATCAATCTACTGCAGATGCAGCAGTTTAATCATCAGGTGCAGACAG
ATATAGGCATCTGTGGTGACGAATGCAGCACCATGCTTTCTACCTTTTTCAAAGAGCTGCGAAAGAAGCGCAAGCTTCAA
GGGCAGTAA

Upstream 100 bases:

>100_bases
AGAACAAGAAAAACTGCTGCTTACATGCGAGCATGACGCATCAGCTTTTCTTGTTCTCAGTGGTTCTGAATAGTTATTGT
ATTATAATAGATTATAACAC

Downstream 100 bases:

>100_bases
AGACGGCTATATGGATGGAACTTGCTTCTACATAATATACGTTATATACATTTTCTTATGAAAAAAATATCTACAGGTGT
CAGAAATGGAATAAGAAATT

Product: cytidine and deoxycytidylate deaminase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MEQTNMTQDEKYMKQAIKQAKKAYALDEVPIGCVIVAGDKIIARGYNRRNTDKNPLAHAELSAIRKASKKTGDWRLEECT
MYVTLEPCQMCAGAIVQARIPRVVIGAMNPKAGCAGSIINLLQMQQFNHQVQTDIGICGDECSTMLSTFFKELRKKRKLQ
GQ

Sequences:

>Translated_162_residues
MEQTNMTQDEKYMKQAIKQAKKAYALDEVPIGCVIVAGDKIIARGYNRRNTDKNPLAHAELSAIRKASKKTGDWRLEECT
MYVTLEPCQMCAGAIVQARIPRVVIGAMNPKAGCAGSIINLLQMQQFNHQVQTDIGICGDECSTMLSTFFKELRKKRKLQ
GQ
>Mature_162_residues
MEQTNMTQDEKYMKQAIKQAKKAYALDEVPIGCVIVAGDKIIARGYNRRNTDKNPLAHAELSAIRKASKKTGDWRLEECT
MYVTLEPCQMCAGAIVQARIPRVVIGAMNPKAGCAGSIINLLQMQQFNHQVQTDIGICGDECSTMLSTFFKELRKKRKLQ
GQ

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=153, Percent_Identity=35.9477124183007, Blast_Score=97, Evalue=8e-21,
Organism=Escherichia coli, GI145693172, Length=151, Percent_Identity=43.7086092715232, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1786616, Length=155, Percent_Identity=32.258064516129, Blast_Score=68, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17541138, Length=149, Percent_Identity=36.241610738255, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17554608, Length=107, Percent_Identity=38.3177570093458, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322425, Length=120, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325319, Length=100, Percent_Identity=37, Blast_Score=65, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=31.5068493150685, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18096; Mature: 18096

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
9.3 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
9.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTNMTQDEKYMKQAIKQAKKAYALDEVPIGCVIVAGDKIIARGYNRRNTDKNPLAHAE
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEECCCCCCCCCCCCHHHHH
LSAIRKASKKTGDWRLEECTMYVTLEPCQMCAGAIVQARIPRVVIGAMNPKAGCAGSIIN
HHHHHHHHHCCCCEEEEHEEEEEEECHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHH
LLQMQQFNHQVQTDIGICGDECSTMLSTFFKELRKKRKLQGQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEQTNMTQDEKYMKQAIKQAKKAYALDEVPIGCVIVAGDKIIARGYNRRNTDKNPLAHAE
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEECCCCCCCCCCCCHHHHH
LSAIRKASKKTGDWRLEECTMYVTLEPCQMCAGAIVQARIPRVVIGAMNPKAGCAGSIIN
HHHHHHHHHCCCCEEEEHEEEEEEECHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHH
LLQMQQFNHQVQTDIGICGDECSTMLSTFFKELRKKRKLQGQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]