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The map label for this gene is ypnP [H]

Identifier: 238922676

GI number: 238922676

Start: 233885

End: 235228

Strand: Direct

Name: ypnP [H]

Synonym: EUBREC_0251

Alternate gene names: 238922676

Gene position: 233885-235228 (Clockwise)

Preceding gene: 238922675

Following gene: 238922677

Centisome position: 6.78

GC content: 46.13

Gene sequence:

>1344_bases
ATGAAGACAGACATGACTAAAGGCAATCCAATGAAAATTATACTGCTGTTCTCGATTCCTGTTCTGATGGGAAATCTGTT
TCAGCAGTTCTATAATATGGTGGACACGATTATCGTGGGGCAGTATCTGGGCTCAAAGGCGCTTGCGGCGGTTGGTTCGA
CAGGCTGTATTATGTTTCTGGTGCTTGGCTTTGCAAATGGAATAGCACAGGGCTTTGGAGTTATGGCAAGCCATGCGTTT
GGTGCGAAAAAAGAGAAGCTTTTGAAGCATTATGTGGCTTTAGCTATCATTCTTACTGTGATTGTTTCAGTGGTGCTCAC
GATTCCGACAGTGCTTGCGTCGAGGCAGCTTCTTATCTGGCTCAATACACCTGATGATATACTTGTCATGGCTGATGCGT
ACATAAAGGTCATTTTTGCGGGAATTTTCTGCACCATGTCCTACAATGTGGCTTCCGGTCTTTTGCGAAGTATCGGAGAC
AGCAAGACTCCGCTGTACTTTTTGATTTTTTCATCTGTATTGAATATTGTGCTGGATATATTCTTTATCGTGGTGGTGAA
GGCAGGCACAGCAGGAGCTGCTTATGCGACAGTTATCTCGCAGGGAATTGCTGCAGTTTTGTCATTTATCGTGATGTTTA
AGAAGTATGATTTGCTGCGCACCAGCCGTGAGGATTATTACATGGACTGGAGCGGAATCTGGCGCATGCTCTCAATCGGT
CTGCAGATGGCACTCAACTATTCAATCACTGCTATCGGAACGATGATCTTCCAGGCTGCGGTCAATGTGTTCGGTTCGCA
GGTGGTAGCTGCGTATACCGCCGCATCCAAGGTCAGCAATATCGCGACACAGACCATGCCTACACTTGGAACAGCCGCTG
CGACTTACTGCGGACAAAATCTTGGAGCAGGAAGATACGACAGGATATTTAAGGGTATGAAGTCATGCTTTTTCATATGT
ATAGGCTGCGCAGTTTTAGCGGCAGCAATTAACTGCTTTGTCGGACCGTACATGATAGGCTGGTTTATCACATCGCCTAC
GGCAACTGACATTGACTGTGCTATGAAATATCTGAAAATCGCGAGTGTCTTCATGCTTCCTCTTGCATGGATTTTTGCAT
ACAGAAACGGTCTGCAGGGACTTAACAAGGGTCTTGTGCCTATGCTTAGCGGTGCGATGGAGCTTGTGTCGAGATGGATT
GCAATACTTGCCCTGTCAAAGCCATTTGGTTACGGCGGTGTGTGCTTTGCAGATCCGGCAGCCTGGCTTACAACAGGAAT
ACTACTTATTGTGACCTACTATGTGTGGGAGATGCGCATGAGAAAGAAGATACAGATAAAATAG

Upstream 100 bases:

>100_bases
AAAAGAGCTTGTTCACACATTTTTTTAATAGATTTTCTGCAGGGGTGAACCTGCTGGGAAAAGTTATTATGAATTGAATT
TTTGGGGAGGGTATTTACAC

Downstream 100 bases:

>100_bases
ATTTCACACAAATTGGTTTATTCGTGGTACAATTAAGCCACGGATAAATCAATTTCATTTACAGAGATAAAGAGGCGGAT
TGCATGAATTATTATGAGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKTDMTKGNPMKIILLFSIPVLMGNLFQQFYNMVDTIIVGQYLGSKALAAVGSTGCIMFLVLGFANGIAQGFGVMASHAF
GAKKEKLLKHYVALAIILTVIVSVVLTIPTVLASRQLLIWLNTPDDILVMADAYIKVIFAGIFCTMSYNVASGLLRSIGD
SKTPLYFLIFSSVLNIVLDIFFIVVVKAGTAGAAYATVISQGIAAVLSFIVMFKKYDLLRTSREDYYMDWSGIWRMLSIG
LQMALNYSITAIGTMIFQAAVNVFGSQVVAAYTAASKVSNIATQTMPTLGTAAATYCGQNLGAGRYDRIFKGMKSCFFIC
IGCAVLAAAINCFVGPYMIGWFITSPTATDIDCAMKYLKIASVFMLPLAWIFAYRNGLQGLNKGLVPMLSGAMELVSRWI
AILALSKPFGYGGVCFADPAAWLTTGILLIVTYYVWEMRMRKKIQIK

Sequences:

>Translated_447_residues
MKTDMTKGNPMKIILLFSIPVLMGNLFQQFYNMVDTIIVGQYLGSKALAAVGSTGCIMFLVLGFANGIAQGFGVMASHAF
GAKKEKLLKHYVALAIILTVIVSVVLTIPTVLASRQLLIWLNTPDDILVMADAYIKVIFAGIFCTMSYNVASGLLRSIGD
SKTPLYFLIFSSVLNIVLDIFFIVVVKAGTAGAAYATVISQGIAAVLSFIVMFKKYDLLRTSREDYYMDWSGIWRMLSIG
LQMALNYSITAIGTMIFQAAVNVFGSQVVAAYTAASKVSNIATQTMPTLGTAAATYCGQNLGAGRYDRIFKGMKSCFFIC
IGCAVLAAAINCFVGPYMIGWFITSPTATDIDCAMKYLKIASVFMLPLAWIFAYRNGLQGLNKGLVPMLSGAMELVSRWI
AILALSKPFGYGGVCFADPAAWLTTGILLIVTYYVWEMRMRKKIQIK
>Mature_447_residues
MKTDMTKGNPMKIILLFSIPVLMGNLFQQFYNMVDTIIVGQYLGSKALAAVGSTGCIMFLVLGFANGIAQGFGVMASHAF
GAKKEKLLKHYVALAIILTVIVSVVLTIPTVLASRQLLIWLNTPDDILVMADAYIKVIFAGIFCTMSYNVASGLLRSIGD
SKTPLYFLIFSSVLNIVLDIFFIVVVKAGTAGAAYATVISQGIAAVLSFIVMFKKYDLLRTSREDYYMDWSGIWRMLSIG
LQMALNYSITAIGTMIFQAAVNVFGSQVVAAYTAASKVSNIATQTMPTLGTAAATYCGQNLGAGRYDRIFKGMKSCFFIC
IGCAVLAAAINCFVGPYMIGWFITSPTATDIDCAMKYLKIASVFMLPLAWIFAYRNGLQGLNKGLVPMLSGAMELVSRWI
AILALSKPFGYGGVCFADPAAWLTTGILLIVTYYVWEMRMRKKIQIK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=353, Percent_Identity=20.6798866855524, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48653; Mature: 48653

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDMTKGNPMKIILLFSIPVLMGNLFQQFYNMVDTIIVGQYLGSKALAAVGSTGCIMFL
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VLGFANGIAQGFGVMASHAFGAKKEKLLKHYVALAIILTVIVSVVLTIPTVLASRQLLIW
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LNTPDDILVMADAYIKVIFAGIFCTMSYNVASGLLRSIGDSKTPLYFLIFSSVLNIVLDI
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
FFIVVVKAGTAGAAYATVISQGIAAVLSFIVMFKKYDLLRTSREDYYMDWSGIWRMLSIG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHH
LQMALNYSITAIGTMIFQAAVNVFGSQVVAAYTAASKVSNIATQTMPTLGTAAATYCGQN
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
LGAGRYDRIFKGMKSCFFICIGCAVLAAAINCFVGPYMIGWFITSPTATDIDCAMKYLKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHH
ASVFMLPLAWIFAYRNGLQGLNKGLVPMLSGAMELVSRWIAILALSKPFGYGGVCFADPA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCH
AWLTTGILLIVTYYVWEMRMRKKIQIK
HHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKTDMTKGNPMKIILLFSIPVLMGNLFQQFYNMVDTIIVGQYLGSKALAAVGSTGCIMFL
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VLGFANGIAQGFGVMASHAFGAKKEKLLKHYVALAIILTVIVSVVLTIPTVLASRQLLIW
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LNTPDDILVMADAYIKVIFAGIFCTMSYNVASGLLRSIGDSKTPLYFLIFSSVLNIVLDI
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
FFIVVVKAGTAGAAYATVISQGIAAVLSFIVMFKKYDLLRTSREDYYMDWSGIWRMLSIG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHH
LQMALNYSITAIGTMIFQAAVNVFGSQVVAAYTAASKVSNIATQTMPTLGTAAATYCGQN
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
LGAGRYDRIFKGMKSCFFICIGCAVLAAAINCFVGPYMIGWFITSPTATDIDCAMKYLKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHH
ASVFMLPLAWIFAYRNGLQGLNKGLVPMLSGAMELVSRWIAILALSKPFGYGGVCFADPA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCH
AWLTTGILLIVTYYVWEMRMRKKIQIK
HHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]