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The map label for this gene is yabD [H]

Identifier: 238922666

GI number: 238922666

Start: 222963

End: 223742

Strand: Direct

Name: yabD [H]

Synonym: EUBREC_0241

Alternate gene names: 238922666

Gene position: 222963-223742 (Clockwise)

Preceding gene: 238922665

Following gene: 238922667

Centisome position: 6.46

GC content: 45.77

Gene sequence:

>780_bases
ATGATATTTGAAACACATGCCCATTATGATGATGACAGATTTAAGGACGACCGTGATGAAACAATAAAACGCGTCCATGA
AAAAGGAGTTGCCCCGATAATAAATGTCGGGGCTTCTATTGGCTCTACCATGACTACAATAGAGCTTGCAAAGAAATATG
ACTTTATATATGCAGCGGTTGGAGTGCATCCAAGCGACGTAGCTGATTTAAACGAGGAAACCTTTGCATGGCTTAGGGAA
CAGACTGCATGGGAAAGGACTGTTGCAGTCGGGGAAATCGGACTGGACTATTACTGGGATAAGGAGCCAAAGGTGCAGGA
AAACCAGCGCTACTGGTTTAAGCGTCAGCTTGAGCTTGCAGCAGAAGCATCGCTGCCGGTTATCATCCACTCGCGTGATG
CAGCACAGGACACCATGGAAATCATGACAGAGGCAGCAAAAAAGGATATCCGCGGCGTGATACACTGCTATTCCTATTCA
CCGGAGATGGCACTGGAGTATGTAAAGCTGGGGTATTATATCGGAGTTGGAGGTGTCGTAACTTTCAAGAATGCAAAGAA
GCTGGTACAGACAGTGTCAGAGCTTCCACTTGATAGAATCCTTCTTGAGACAGATTGTCCATACATGGCTCCGGAGCCAC
ATCGAGGCACGAGGAATGATTCGTCAAACATTCCATATGTAATATCAAAGATAGCAGAAATCAAAGGCACTACGCCTGAT
GAGGTAGAGCGCAAAACCCGTGCAAATGCATTTGAACTTTTCACGCGTGTAAGTGATTGA

Upstream 100 bases:

>100_bases
CTGAGAGCGCAGAGCATCTGTGCAACAAGTGTAAGGAGTATGCGCAGGCATGGAAGCCTTGTGCCGATAAGCTTTGGGCG
GAGGAAGGACACAGTAATTA

Downstream 100 bases:

>100_bases
GCCACAACATGAGGGACGAAAGTCGGGAACCGCCGCCCTGCCATGGGGCACGGTACACTCCCGCGTGAGCGAATAGCGAA
GCGGTTTAGATACTGTAGGA

Product: putative deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MIFETHAHYDDDRFKDDRDETIKRVHEKGVAPIINVGASIGSTMTTIELAKKYDFIYAAVGVHPSDVADLNEETFAWLRE
QTAWERTVAVGEIGLDYYWDKEPKVQENQRYWFKRQLELAAEASLPVIIHSRDAAQDTMEIMTEAAKKDIRGVIHCYSYS
PEMALEYVKLGYYIGVGGVVTFKNAKKLVQTVSELPLDRILLETDCPYMAPEPHRGTRNDSSNIPYVISKIAEIKGTTPD
EVERKTRANAFELFTRVSD

Sequences:

>Translated_259_residues
MIFETHAHYDDDRFKDDRDETIKRVHEKGVAPIINVGASIGSTMTTIELAKKYDFIYAAVGVHPSDVADLNEETFAWLRE
QTAWERTVAVGEIGLDYYWDKEPKVQENQRYWFKRQLELAAEASLPVIIHSRDAAQDTMEIMTEAAKKDIRGVIHCYSYS
PEMALEYVKLGYYIGVGGVVTFKNAKKLVQTVSELPLDRILLETDCPYMAPEPHRGTRNDSSNIPYVISKIAEIKGTTPD
EVERKTRANAFELFTRVSD
>Mature_259_residues
MIFETHAHYDDDRFKDDRDETIKRVHEKGVAPIINVGASIGSTMTTIELAKKYDFIYAAVGVHPSDVADLNEETFAWLRE
QTAWERTVAVGEIGLDYYWDKEPKVQENQRYWFKRQLELAAEASLPVIIHSRDAAQDTMEIMTEAAKKDIRGVIHCYSYS
PEMALEYVKLGYYIGVGGVVTFKNAKKLVQTVSELPLDRILLETDCPYMAPEPHRGTRNDSSNIPYVISKIAEIKGTTPD
EVERKTRANAFELFTRVSD

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=28.0898876404494, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=27.7153558052434, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI226061853, Length=275, Percent_Identity=28, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI226061614, Length=259, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=26.9565217391304, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI14042943, Length=214, Percent_Identity=25.2336448598131, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI225903424, Length=163, Percent_Identity=33.7423312883436, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI225903439, Length=191, Percent_Identity=24.6073298429319, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1787342, Length=260, Percent_Identity=34.2307692307692, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=33.7209302325581, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=28.2945736434109, Blast_Score=122, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17559024, Length=280, Percent_Identity=27.8571428571429, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=27.1698113207547, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17543026, Length=214, Percent_Identity=28.5046728971963, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17565396, Length=214, Percent_Identity=27.5700934579439, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648690, Length=288, Percent_Identity=29.8611111111111, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24586117, Length=223, Percent_Identity=35.8744394618834, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI221330018, Length=223, Percent_Identity=35.8744394618834, Blast_Score=110, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29530; Mature: 29530

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFETHAHYDDDRFKDDRDETIKRVHEKGVAPIINVGASIGSTMTTIELAKKYDFIYAAV
CEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCHHHCCHHHHHHHHHHHCEEEEEE
GVHPSDVADLNEETFAWLREQTAWERTVAVGEIGLDYYWDKEPKVQENQRYWFKRQLELA
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHH
AEASLPVIIHSRDAAQDTMEIMTEAAKKDIRGVIHCYSYSPEMALEYVKLGYYIGVGGVV
HHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCEE
TFKNAKKLVQTVSELPLDRILLETDCPYMAPEPHRGTRNDSSNIPYVISKIAEIKGTTPD
EEHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHH
EVERKTRANAFELFTRVSD
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIFETHAHYDDDRFKDDRDETIKRVHEKGVAPIINVGASIGSTMTTIELAKKYDFIYAAV
CEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCHHHCCHHHHHHHHHHHCEEEEEE
GVHPSDVADLNEETFAWLREQTAWERTVAVGEIGLDYYWDKEPKVQENQRYWFKRQLELA
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHH
AEASLPVIIHSRDAAQDTMEIMTEAAKKDIRGVIHCYSYSPEMALEYVKLGYYIGVGGVV
HHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCEE
TFKNAKKLVQTVSELPLDRILLETDCPYMAPEPHRGTRNDSSNIPYVISKIAEIKGTTPD
EEHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHH
EVERKTRANAFELFTRVSD
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]