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The map label for this gene is dcm [C]

Identifier: 238922582

GI number: 238922582

Start: 151478

End: 152809

Strand: Direct

Name: dcm [C]

Synonym: EUBREC_0156

Alternate gene names: 238922582

Gene position: 151478-152809 (Clockwise)

Preceding gene: 238922581

Following gene: 238922583

Centisome position: 4.39

GC content: 37.39

Gene sequence:

>1332_bases
ATGTTACCTAAAATTATTGATCTGTTTTCAGGGTGTGGTGGATTGGCACTCGGATTTGAAAAAGCGGGTTTTGATATTGT
GGCAGGAATTGAATTGATGCCAGAAGCATGTAAAACCATTTCTTATAATCTTTCCTGGCGCTATGGAAAAAAAGAAACAC
ATATATGTGGAGATATAACAGAAATAGAAGCAAGTGTGTTTAAAAATAGTTTTGGAGATGAGGGGTGTATTGTTATAGGA
GGACCGCCATGCCAGGCGTATTCTATGGCAGGTCGCGGGAAACTTAGATCACTCGGTGAAGATAGAGTAAATATAAAAGA
TGCAAGAGGATATCTGTATCAGGATTTTTTGAGATTTGTATTTGAATTGGAAGCAAGAGCTGTTGTGATGGAGAATGTTC
CGGAATCAACAAATTTTGGCGGTAAAAATATACCAGAAATAGTATGTACTGAGTTAACTAAAAAAGGTTATAAGGCATAT
TGGACAATACTTAATTCTGCCGACTATGGTGTTCCACAGGTAAGAGAGAGAGTTTTTGTTGTAGCAATCAAGGGGGATGA
AGGAAAAGAGATAAAATTACCAAATCCAACACATCGAAATGAGGTTGATGTATTGACCCAGCATCAAAAACGATTTGAGG
GATATAAGCAATGTCAATTTTTTGTGGAACCCAATGGAACAACAGATGAATTAAAACCATGGGTTACTGTAGGAGATGCT
TTTTCAGATTTACCAGAAGTATTTCCGACAGCAGACTCAAAATATAAATTGGTGTCATTAAATATTGAGTATCCATATAA
AACGGAAGCACAGAATGAATATCAAGAATTAATGAGAACCTGGTATGGTAAAGAGGGATTTGGTGTTTCGGCAAATGCAT
TCAGAAGGAATACCAGAGATTTCCCGATCTTTGAGAGAATGCAACAAGGAGATAATTATATTGCGGCGACAAAGATAGCA
GAAGAGCTATTCTATGAAGAGGCAAAACTTTTTGGGTACGAGAAGGATAGTGAGGAATACATTAGTCTCTATAATAAAAT
GGTTCCGCAATATGATAAAGATAAATTCGAAAATAAATGGAAGCGGTTGGATGAAACGAAACCATCACATACATTAGTGG
CACATTTGGCAAAGGACACGTATAGTCATATTCATCCGATTGAACCAAGGGGAATTACAGTAAGAGAGGCAGCAAGGTTA
CAATCTTTTCCGGATGATTTTTTCTTTGATTGTTCTATGGGGGATGCATTTAAGCAAATTGGAAATGCTGTGCCCCCGCT
ATTGGCGTATGGAGTTGCAAGAACAGTGTTGAATACTTTTGAGGAGGAATAG

Upstream 100 bases:

>100_bases
TGAACACTGCTAAAGTGATGGTTGTGGATCCGGCATTATATTTGGGTGGCGAAAAAGAATATGTACGCTCTTTATTTATA
GACGCGGGGGTGCGTGTGTA

Downstream 100 bases:

>100_bases
ACCATGGGAATACTGGAGGAGATTAGAGAGTATTTTGCATCGACACAAAATGGTGCAAGAGAAATTAAAACGTTACCAAA
AGAATACTCAGCAATGGTTA

Product: cytosine-specific methyltransferase

Products: NA

Alternate protein names: Cytosine-specific methyltransferase; M.OihORF3336P [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MLPKIIDLFSGCGGLALGFEKAGFDIVAGIELMPEACKTISYNLSWRYGKKETHICGDITEIEASVFKNSFGDEGCIVIG
GPPCQAYSMAGRGKLRSLGEDRVNIKDARGYLYQDFLRFVFELEARAVVMENVPESTNFGGKNIPEIVCTELTKKGYKAY
WTILNSADYGVPQVRERVFVVAIKGDEGKEIKLPNPTHRNEVDVLTQHQKRFEGYKQCQFFVEPNGTTDELKPWVTVGDA
FSDLPEVFPTADSKYKLVSLNIEYPYKTEAQNEYQELMRTWYGKEGFGVSANAFRRNTRDFPIFERMQQGDNYIAATKIA
EELFYEEAKLFGYEKDSEEYISLYNKMVPQYDKDKFENKWKRLDETKPSHTLVAHLAKDTYSHIHPIEPRGITVREAARL
QSFPDDFFFDCSMGDAFKQIGNAVPPLLAYGVARTVLNTFEEE

Sequences:

>Translated_443_residues
MLPKIIDLFSGCGGLALGFEKAGFDIVAGIELMPEACKTISYNLSWRYGKKETHICGDITEIEASVFKNSFGDEGCIVIG
GPPCQAYSMAGRGKLRSLGEDRVNIKDARGYLYQDFLRFVFELEARAVVMENVPESTNFGGKNIPEIVCTELTKKGYKAY
WTILNSADYGVPQVRERVFVVAIKGDEGKEIKLPNPTHRNEVDVLTQHQKRFEGYKQCQFFVEPNGTTDELKPWVTVGDA
FSDLPEVFPTADSKYKLVSLNIEYPYKTEAQNEYQELMRTWYGKEGFGVSANAFRRNTRDFPIFERMQQGDNYIAATKIA
EELFYEEAKLFGYEKDSEEYISLYNKMVPQYDKDKFENKWKRLDETKPSHTLVAHLAKDTYSHIHPIEPRGITVREAARL
QSFPDDFFFDCSMGDAFKQIGNAVPPLLAYGVARTVLNTFEEE
>Mature_443_residues
MLPKIIDLFSGCGGLALGFEKAGFDIVAGIELMPEACKTISYNLSWRYGKKETHICGDITEIEASVFKNSFGDEGCIVIG
GPPCQAYSMAGRGKLRSLGEDRVNIKDARGYLYQDFLRFVFELEARAVVMENVPESTNFGGKNIPEIVCTELTKKGYKAY
WTILNSADYGVPQVRERVFVVAIKGDEGKEIKLPNPTHRNEVDVLTQHQKRFEGYKQCQFFVEPNGTTDELKPWVTVGDA
FSDLPEVFPTADSKYKLVSLNIEYPYKTEAQNEYQELMRTWYGKEGFGVSANAFRRNTRDFPIFERMQQGDNYIAATKIA
EELFYEEAKLFGYEKDSEEYISLYNKMVPQYDKDKFENKWKRLDETKPSHTLVAHLAKDTYSHIHPIEPRGITVREAARL
QSFPDDFFFDCSMGDAFKQIGNAVPPLLAYGVARTVLNTFEEE

Specific function: This methylase recognizes the double-stranded sequence ACCGGT, causes specific methylation on C-? on both strands, and protects the DNA from cleavage by a specific endonuclease (Potential) [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4503351, Length=487, Percent_Identity=26.2833675564682, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI195927037, Length=487, Percent_Identity=26.2833675564682, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1788271, Length=204, Percent_Identity=28.921568627451, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 50455; Mature: 50455

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00095 C5_MTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPKIIDLFSGCGGLALGFEKAGFDIVAGIELMPEACKTISYNLSWRYGKKETHICGDIT
CCHHHHHHHCCCCCCEECHHHCCCEEEEHHHHHHHHHHHEEECEEEEECCCCCCCCCCHH
EIEASVFKNSFGDEGCIVIGGPPCQAYSMAGRGKLRSLGEDRVNIKDARGYLYQDFLRFV
HHHHHHHHCCCCCCCEEEECCCCCCHHCCCCCCHHHHCCCCCCCEEHHHHHHHHHHHHHH
FELEARAVVMENVPESTNFGGKNIPEIVCTELTKKGYKAYWTILNSADYGVPQVRERVFV
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHCCCEEE
VAIKGDEGKEIKLPNPTHRNEVDVLTQHQKRFEGYKQCQFFVEPNGTTDELKPWVTVGDA
EEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCCEEECHH
FSDLPEVFPTADSKYKLVSLNIEYPYKTEAQNEYQELMRTWYGKEGFGVSANAFRRNTRD
HHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCC
FPIFERMQQGDNYIAATKIAEELFYEEAKLFGYEKDSEEYISLYNKMVPQYDKDKFENKW
CHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
KRLDETKPSHTLVAHLAKDTYSHIHPIEPRGITVREAARLQSFPDDFFFDCSMGDAFKQI
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCHHHHHH
GNAVPPLLAYGVARTVLNTFEEE
CCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLPKIIDLFSGCGGLALGFEKAGFDIVAGIELMPEACKTISYNLSWRYGKKETHICGDIT
CCHHHHHHHCCCCCCEECHHHCCCEEEEHHHHHHHHHHHEEECEEEEECCCCCCCCCCHH
EIEASVFKNSFGDEGCIVIGGPPCQAYSMAGRGKLRSLGEDRVNIKDARGYLYQDFLRFV
HHHHHHHHCCCCCCCEEEECCCCCCHHCCCCCCHHHHCCCCCCCEEHHHHHHHHHHHHHH
FELEARAVVMENVPESTNFGGKNIPEIVCTELTKKGYKAYWTILNSADYGVPQVRERVFV
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHCCCEEE
VAIKGDEGKEIKLPNPTHRNEVDVLTQHQKRFEGYKQCQFFVEPNGTTDELKPWVTVGDA
EEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCCEEECHH
FSDLPEVFPTADSKYKLVSLNIEYPYKTEAQNEYQELMRTWYGKEGFGVSANAFRRNTRD
HHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCC
FPIFERMQQGDNYIAATKIAEELFYEEAKLFGYEKDSEEYISLYNKMVPQYDKDKFENKW
CHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
KRLDETKPSHTLVAHLAKDTYSHIHPIEPRGITVREAARLQSFPDDFFFDCSMGDAFKQI
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCHHHHHH
GNAVPPLLAYGVARTVLNTFEEE
CCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]