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The map label for this gene is atpB [H]

Identifier: 238922544

GI number: 238922544

Start: 114203

End: 114940

Strand: Direct

Name: atpB [H]

Synonym: EUBREC_0118

Alternate gene names: 238922544

Gene position: 114203-114940 (Clockwise)

Preceding gene: 238922543

Following gene: 238922545

Centisome position: 3.31

GC content: 43.22

Gene sequence:

>738_bases
GTGAATCAGGCGATTTTACTGGAAAGTAACGCAGACAATATCGACTTTATGATCCATGGTATTTTTTCGATAAAGGTATT
CGGTCAGGAGGTCTGGATTACCACATCGCATGCCTGTATCCTCATAGTGATGGCCATTATGGTCATATTCGCTATAGTGG
CAAACAGGAAGCTTAAAAAAGCAAAGGAAGTACCGGACGGCTTTCAGAATATCATCGAGCTTATCGTAGAGATGCTCGAC
AAGATGGTTGAGGGAACCATGGGTAAGTGGGCTCCGAGGTTTGTAAACTACATCAGTACGATTTTTATATTTATACTGAT
GAGTAATATCTCAGGCTTGTTTGGCTTAAGACCACCGACAGCCGACTACGGAACCACACTGGCGCTTGCACTTATTACAT
TTTTCATGATCAGATTCAATAAGGCTAAGCATCAAAGCGCAAAGGATATCTGGACCGGTATGTGTTCACCACTGCCGCCG
TGGCTGCCTATATGGGCGCCAATCAACATTATCAGTGAGATTGCAATTCCTATCTCATTATCATTGCGTTTGTTCGCCAA
TGTGTTGTCAGGAACTGTTATCATGGCGCTGGTATATGGTCTGCTAAGGTTTATAGCCATAGCGTGGCCGTCAGTACTGC
ATGTATACTTTGATTTGTTCTCAGGAGCAATTCAGACATATGTATTCTGTATGCTGACAATGACATACGTTACACAGGCA
TGTGAGACGGATGAGTAA

Upstream 100 bases:

>100_bases
GACAGACAGATTTTCCGGGAGAAGTGATGCATCTTCCGCCGGCGAAATGGAGACAGAGTAGCAAAACAGCAGGTAAACTT
AATAAGGAGGAGGTGATAAT

Downstream 100 bases:

>100_bases
AACTATAAGATGTATTTTTAGGAGGATTCAATTATGGATATCAATGGACAGGATTTAATCAGAGCATGCTCAGCAATCGG
TGCAGGTTTGGCAGTTATCG

Product: AtpB

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNQAILLESNADNIDFMIHGIFSIKVFGQEVWITTSHACILIVMAIMVIFAIVANRKLKKAKEVPDGFQNIIELIVEMLD
KMVEGTMGKWAPRFVNYISTIFIFILMSNISGLFGLRPPTADYGTTLALALITFFMIRFNKAKHQSAKDIWTGMCSPLPP
WLPIWAPINIISEIAIPISLSLRLFANVLSGTVIMALVYGLLRFIAIAWPSVLHVYFDLFSGAIQTYVFCMLTMTYVTQA
CETDE

Sequences:

>Translated_245_residues
MNQAILLESNADNIDFMIHGIFSIKVFGQEVWITTSHACILIVMAIMVIFAIVANRKLKKAKEVPDGFQNIIELIVEMLD
KMVEGTMGKWAPRFVNYISTIFIFILMSNISGLFGLRPPTADYGTTLALALITFFMIRFNKAKHQSAKDIWTGMCSPLPP
WLPIWAPINIISEIAIPISLSLRLFANVLSGTVIMALVYGLLRFIAIAWPSVLHVYFDLFSGAIQTYVFCMLTMTYVTQA
CETDE
>Mature_245_residues
MNQAILLESNADNIDFMIHGIFSIKVFGQEVWITTSHACILIVMAIMVIFAIVANRKLKKAKEVPDGFQNIIELIVEMLD
KMVEGTMGKWAPRFVNYISTIFIFILMSNISGLFGLRPPTADYGTTLALALITFFMIRFNKAKHQSAKDIWTGMCSPLPP
WLPIWAPINIISEIAIPISLSLRLFANVLSGTVIMALVYGLLRFIAIAWPSVLHVYFDLFSGAIQTYVFCMLTMTYVTQA
CETDE

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=206, Percent_Identity=28.1553398058252, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 27512; Mature: 27512

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQAILLESNADNIDFMIHGIFSIKVFGQEVWITTSHACILIVMAIMVIFAIVANRKLKK
CCCEEEEECCCCCHHHHHHHHHHHEEECCEEEEECCHHHHHHHHHHHHHHHHHHCHHHHH
AKEVPDGFQNIIELIVEMLDKMVEGTMGKWAPRFVNYISTIFIFILMSNISGLFGLRPPT
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ADYGTTLALALITFFMIRFNKAKHQSAKDIWTGMCSPLPPWLPIWAPINIISEIAIPISL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
SLRLFANVLSGTVIMALVYGLLRFIAIAWPSVLHVYFDLFSGAIQTYVFCMLTMTYVTQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CETDE
HCCCC
>Mature Secondary Structure
MNQAILLESNADNIDFMIHGIFSIKVFGQEVWITTSHACILIVMAIMVIFAIVANRKLKK
CCCEEEEECCCCCHHHHHHHHHHHEEECCEEEEECCHHHHHHHHHHHHHHHHHHCHHHHH
AKEVPDGFQNIIELIVEMLDKMVEGTMGKWAPRFVNYISTIFIFILMSNISGLFGLRPPT
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ADYGTTLALALITFFMIRFNKAKHQSAKDIWTGMCSPLPPWLPIWAPINIISEIAIPISL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
SLRLFANVLSGTVIMALVYGLLRFIAIAWPSVLHVYFDLFSGAIQTYVFCMLTMTYVTQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CETDE
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10902917; 11466286 [H]