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The map label for this gene is mecB [H]

Identifier: 238922461

GI number: 238922461

Start: 43629

End: 44369

Strand: Direct

Name: mecB [H]

Synonym: EUBREC_0035

Alternate gene names: 238922461

Gene position: 43629-44369 (Clockwise)

Preceding gene: 238922460

Following gene: 238922463

Centisome position: 1.26

GC content: 43.05

Gene sequence:

>741_bases
ATGAAAATTGAGAAGGTAAATGATAATCAGATCCGCTGTACTCTTACCAGAGAGGATCTTGAGGACAGACATATAAAAAT
AAGCGAACTGGCATATGGATCAGCGAAGGCGAAAAGCCTTTTTAAAGATATGGTAGAGCAGGCCAATTACGAGTTTGGCT
TTGAAACAAATGATATTCCACTCATGGTGGAGGCAATTCCACTGCCATCAGAGTCTATAGTGCTTATCATCACAAAGGTT
GAATATCCGGATGAGCTTGACACCAGATTTTCAAAGTTTTCAGAGGCAGATGACGACTTTACGGACTTAGGAAATGCAGG
ACAGCCTCCGGTGATAAAGGGAGCTGCTGATATTTTGGAGCTGTTTGAGCGTATCAAGAAGGAAAATGAGAAGACAGCTG
ACAGTGAGCAGGGCACTGATGATATTACAGAAGAACAGGCTGAGGCTGACGTAGTCAAGCTGTTTGTTTTTGATAAATTT
GATGATGTGCGCAGGATTTCGCATGTGCTTGACGGCTTTTACAGCGGCAGAAATGACTTATACCGCGACGCTTCAAGCAA
TAAGTACTATCTTGTGGCCCACAAGAGTGAGCATACTCCGAAGGAATTCAACAAGGTGTGCAACATCATTTCAGAGTACG
CATATCAGAAGAACTATGTGCCTGCCAATGAAGCATTTTTCAAGGAGCATGGTAATGTGATTATTGAAGAAGCTGCCATC
CAGACGCTGGCAGCACTTTAA

Upstream 100 bases:

>100_bases
TATTTTTTTTTAATAGACCTCGCGCTTTACAATATGACCGGTGTTTATTATAATAGTTTTACGATTTACACGGATATTTT
CGGAAAAGGATGTGAAAAAT

Downstream 100 bases:

>100_bases
CAGAATATTGATTGCAAATAAAAGACGGCCTGCATAAGCAAGCCGTCTTTTCGTAAATTAACCGAGGTCGTGATCGATGA
ATGTGTTGATTTCAACGACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKIEKVNDNQIRCTLTREDLEDRHIKISELAYGSAKAKSLFKDMVEQANYEFGFETNDIPLMVEAIPLPSESIVLIITKV
EYPDELDTRFSKFSEADDDFTDLGNAGQPPVIKGAADILELFERIKKENEKTADSEQGTDDITEEQAEADVVKLFVFDKF
DDVRRISHVLDGFYSGRNDLYRDASSNKYYLVAHKSEHTPKEFNKVCNIISEYAYQKNYVPANEAFFKEHGNVIIEEAAI
QTLAAL

Sequences:

>Translated_246_residues
MKIEKVNDNQIRCTLTREDLEDRHIKISELAYGSAKAKSLFKDMVEQANYEFGFETNDIPLMVEAIPLPSESIVLIITKV
EYPDELDTRFSKFSEADDDFTDLGNAGQPPVIKGAADILELFERIKKENEKTADSEQGTDDITEEQAEADVVKLFVFDKF
DDVRRISHVLDGFYSGRNDLYRDASSNKYYLVAHKSEHTPKEFNKVCNIISEYAYQKNYVPANEAFFKEHGNVIIEEAAI
QTLAAL
>Mature_246_residues
MKIEKVNDNQIRCTLTREDLEDRHIKISELAYGSAKAKSLFKDMVEQANYEFGFETNDIPLMVEAIPLPSESIVLIITKV
EYPDELDTRFSKFSEADDDFTDLGNAGQPPVIKGAADILELFERIKKENEKTADSEQGTDDITEEQAEADVVKLFVFDKF
DDVRRISHVLDGFYSGRNDLYRDASSNKYYLVAHKSEHTPKEFNKVCNIISEYAYQKNYVPANEAFFKEHGNVIIEEAAI
QTLAAL

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Also involved in Spx degradation by ClpC. Acts negatively in the development of competence by binding ComK and rec

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 28039; Mature: 28039

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEKVNDNQIRCTLTREDLEDRHIKISELAYGSAKAKSLFKDMVEQANYEFGFETNDIP
CCCCCCCCCEEEEEEECCCCCCCCEEHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
LMVEAIPLPSESIVLIITKVEYPDELDTRFSKFSEADDDFTDLGNAGQPPVIKGAADILE
EEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHH
LFERIKKENEKTADSEQGTDDITEEQAEADVVKLFVFDKFDDVRRISHVLDGFYSGRNDL
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCCHHH
YRDASSNKYYLVAHKSEHTPKEFNKVCNIISEYAYQKNYVPANEAFFKEHGNVIIEEAAI
HHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEHHHHH
QTLAAL
HHHHCC
>Mature Secondary Structure
MKIEKVNDNQIRCTLTREDLEDRHIKISELAYGSAKAKSLFKDMVEQANYEFGFETNDIP
CCCCCCCCCEEEEEEECCCCCCCCEEHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
LMVEAIPLPSESIVLIITKVEYPDELDTRFSKFSEADDDFTDLGNAGQPPVIKGAADILE
EEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHH
LFERIKKENEKTADSEQGTDDITEEQAEADVVKLFVFDKFDDVRRISHVLDGFYSGRNDL
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCCHHH
YRDASSNKYYLVAHKSEHTPKEFNKVCNIISEYAYQKNYVPANEAFFKEHGNVIIEEAAI
HHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEHHHHH
QTLAAL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]