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The map label for this gene is blaR1 [H]

Identifier: 238922290

GI number: 238922290

Start: 488945

End: 490321

Strand: Reverse

Name: blaR1 [H]

Synonym: EUBELI_20526

Alternate gene names: 238922290

Gene position: 490321-488945 (Counterclockwise)

Preceding gene: 238922292

Following gene: 238922289

Centisome position: 78.23

GC content: 35.73

Gene sequence:

>1377_bases
ATGCTATGGACAGATTTATTTTACATGATTGTCATAACTACATTTACGGGTAGTGTGCTAACTGTTGCGTGGCTTATAAC
TTCATATTTACTTGATAAGACAGGATATCTTAATATGTCATACAGACTTGGAAAAGTTGTTGTATTGTTCTGGATAATTC
CGGTAATGTATTACGCGATAAGAATGATTGACCACTTAAGGTTCGTGTGGAATGGTTACGCATTTGATACATCACCGCTT
ATTATTAATGTGACAAGAGCTGTTGCTATTGTGTGGATAACAGGTCTGGCTGTTGCAATAATGATTTATGTGTTTAAGAG
ATTCAGAATTTTATCAATAAGGAAAGAATCATTTGCCTGTAATAAGGAGATGAACAGGATTTTCTATGAGATAAAAGAAC
AGATGGGACTTGGGAAATGTAAAATTACATTAAGGCAGTCATACAGAACAACTACTGCATATGTGACAGGAATACACAGA
CCGTGTGTTGTTGTTAATGCAGATCATTTTTCTGAGAAAGAGATGAGAGTTGTATTTGCACATGAACTTACACATGTGGT
TCATAATGATATATGGTTCAGATATCTTCTTGCGGTGGCAAGTATACTTAATTTCTTTAATCCGGTTATATGGATTTTTT
ACAGAAGATTTATTAAATATGCTGAGTATGCATGTGACTATTCTGTATGTATGTCAGAGAATGGATTACATGAATATTAT
GAAACAATATTTAATCTTGCTGTGAGAAATAATAATCTTTATGACATGCTGTCTGCAAGTCTGTATGAAAATAAAAGCAG
TTTAAGAGAAAGAATGGAGCATGTTATGAAGAGTTATAATGTTAAGAAAAGACCAATGGCTGTTGCAGCAGCTATACTGA
CTTTATTTGTTGCTATGAGTTCTGTTATGGTGGCGGGAGCAGCTACAACCGTAACTGAAACATCAGTTAAGGTTGCGGAG
GCAACTGCTGATGAAAAAAGAGAGCTACAGGTATTAGAAACAGAATATTATGAGGCTGCTGATTATGAAAATCCAGCGGT
TACAGATGTGTATGAAGAAGATGTTAATCCTGATGAAATAATGCCATGTGCTTCAAATGGTACAATCTCATGGGATGTAT
ATGCCGGGGTAAGGAGGTCAACATCAAGCTTTCATGCATCTTCTGGACAGAGGATAGTTTTAAGTGTATTTTCGGTGGAA
CCATTTCATAGCGTAAGAGCGGGAATTATACAGCCTGATGGTTCGAAGAGATATATTATTGCCAATGGCAATGACTCACA
CATATTTGAGCTGACAATGAGTGGTTCATACAGAATATATATCCAGAATGAAACAACAGAGAGTGTTCATGTTGAAGGAG
CGTATTCTACACATTAA

Upstream 100 bases:

>100_bases
ATACCATTTTATACAAAGAAGTTCTATGTTTTTATATAAAAATGTGATATATTTATTAATATGTCGGATTTATATATTTA
ACTTAGGAGTGCAGCAGATT

Downstream 100 bases:

>100_bases
TTAGTATGTATTAGTTGAGGTTGAGAAGATATGAAGATTTTGCATTGTGCAGATATTCATCTGGATTCAGCGATGACGGC
TAATCTTGATAAAGATAAGG

Product: methicillin resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MLWTDLFYMIVITTFTGSVLTVAWLITSYLLDKTGYLNMSYRLGKVVVLFWIIPVMYYAIRMIDHLRFVWNGYAFDTSPL
IINVTRAVAIVWITGLAVAIMIYVFKRFRILSIRKESFACNKEMNRIFYEIKEQMGLGKCKITLRQSYRTTTAYVTGIHR
PCVVVNADHFSEKEMRVVFAHELTHVVHNDIWFRYLLAVASILNFFNPVIWIFYRRFIKYAEYACDYSVCMSENGLHEYY
ETIFNLAVRNNNLYDMLSASLYENKSSLRERMEHVMKSYNVKKRPMAVAAAILTLFVAMSSVMVAGAATTVTETSVKVAE
ATADEKRELQVLETEYYEAADYENPAVTDVYEEDVNPDEIMPCASNGTISWDVYAGVRRSTSSFHASSGQRIVLSVFSVE
PFHSVRAGIIQPDGSKRYIIANGNDSHIFELTMSGSYRIYIQNETTESVHVEGAYSTH

Sequences:

>Translated_458_residues
MLWTDLFYMIVITTFTGSVLTVAWLITSYLLDKTGYLNMSYRLGKVVVLFWIIPVMYYAIRMIDHLRFVWNGYAFDTSPL
IINVTRAVAIVWITGLAVAIMIYVFKRFRILSIRKESFACNKEMNRIFYEIKEQMGLGKCKITLRQSYRTTTAYVTGIHR
PCVVVNADHFSEKEMRVVFAHELTHVVHNDIWFRYLLAVASILNFFNPVIWIFYRRFIKYAEYACDYSVCMSENGLHEYY
ETIFNLAVRNNNLYDMLSASLYENKSSLRERMEHVMKSYNVKKRPMAVAAAILTLFVAMSSVMVAGAATTVTETSVKVAE
ATADEKRELQVLETEYYEAADYENPAVTDVYEEDVNPDEIMPCASNGTISWDVYAGVRRSTSSFHASSGQRIVLSVFSVE
PFHSVRAGIIQPDGSKRYIIANGNDSHIFELTMSGSYRIYIQNETTESVHVEGAYSTH
>Mature_458_residues
MLWTDLFYMIVITTFTGSVLTVAWLITSYLLDKTGYLNMSYRLGKVVVLFWIIPVMYYAIRMIDHLRFVWNGYAFDTSPL
IINVTRAVAIVWITGLAVAIMIYVFKRFRILSIRKESFACNKEMNRIFYEIKEQMGLGKCKITLRQSYRTTTAYVTGIHR
PCVVVNADHFSEKEMRVVFAHELTHVVHNDIWFRYLLAVASILNFFNPVIWIFYRRFIKYAEYACDYSVCMSENGLHEYY
ETIFNLAVRNNNLYDMLSASLYENKSSLRERMEHVMKSYNVKKRPMAVAAAILTLFVAMSSVMVAGAATTVTETSVKVAE
ATADEKRELQVLETEYYEAADYENPAVTDVYEEDVNPDEIMPCASNGTISWDVYAGVRRSTSSFHASSGQRIVLSVFSVE
PFHSVRAGIIQPDGSKRYIIANGNDSHIFELTMSGSYRIYIQNETTESVHVEGAYSTH

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG4219

COG function: function code KT; Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 52590; Mature: 52590

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWTDLFYMIVITTFTGSVLTVAWLITSYLLDKTGYLNMSYRLGKVVVLFWIIPVMYYAI
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
RMIDHLRFVWNGYAFDTSPLIINVTRAVAIVWITGLAVAIMIYVFKRFRILSIRKESFAC
HHHHHHHHHHCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHH
NKEMNRIFYEIKEQMGLGKCKITLRQSYRTTTAYVTGIHRPCVVVNADHFSEKEMRVVFA
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHEEEECCCCEEEEECCCCCCCHHHHHHH
HELTHVVHNDIWFRYLLAVASILNFFNPVIWIFYRRFIKYAEYACDYSVCMSENGLHEYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHH
ETIFNLAVRNNNLYDMLSASLYENKSSLRERMEHVMKSYNVKKRPMAVAAAILTLFVAMS
HHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
SVMVAGAATTVTETSVKVAEATADEKRELQVLETEYYEAADYENPAVTDVYEEDVNPDEI
HHHHHCCHHEEECCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHC
MPCASNGTISWDVYAGVRRSTSSFHASSGQRIVLSVFSVEPFHSVRAGIIQPDGSKRYII
CCCCCCCCEEEEEHHCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHCCCCCCCCCEEEEE
ANGNDSHIFELTMSGSYRIYIQNETTESVHVEGAYSTH
ECCCCCEEEEEEECCCEEEEEECCCCCEEEECCCCCCC
>Mature Secondary Structure
MLWTDLFYMIVITTFTGSVLTVAWLITSYLLDKTGYLNMSYRLGKVVVLFWIIPVMYYAI
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
RMIDHLRFVWNGYAFDTSPLIINVTRAVAIVWITGLAVAIMIYVFKRFRILSIRKESFAC
HHHHHHHHHHCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHH
NKEMNRIFYEIKEQMGLGKCKITLRQSYRTTTAYVTGIHRPCVVVNADHFSEKEMRVVFA
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHEEEECCCCEEEEECCCCCCCHHHHHHH
HELTHVVHNDIWFRYLLAVASILNFFNPVIWIFYRRFIKYAEYACDYSVCMSENGLHEYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHH
ETIFNLAVRNNNLYDMLSASLYENKSSLRERMEHVMKSYNVKKRPMAVAAAILTLFVAMS
HHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
SVMVAGAATTVTETSVKVAEATADEKRELQVLETEYYEAADYENPAVTDVYEEDVNPDEI
HHHHHCCHHEEECCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHC
MPCASNGTISWDVYAGVRRSTSSFHASSGQRIVLSVFSVEPFHSVRAGIIQPDGSKRYII
CCCCCCCCEEEEEHHCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHCCCCCCCCCEEEEE
ANGNDSHIFELTMSGSYRIYIQNETTESVHVEGAYSTH
ECCCCCEEEEEEECCCEEEEEECCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]