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The map label for this gene is tig [H]

Identifier: 238922260

GI number: 238922260

Start: 457433

End: 458470

Strand: Reverse

Name: tig [H]

Synonym: EUBELI_20495

Alternate gene names: 238922260

Gene position: 458470-457433 (Counterclockwise)

Preceding gene: 238922261

Following gene: 238922257

Centisome position: 73.15

GC content: 34.68

Gene sequence:

>1038_bases
ATGAAGAAGACAGCAGTTGCTTTATTATCAGTTTCTATGCTTATGGTAACGGCATGTAATAGTAAGATTGATGTTAAGTA
TGATTATAATGTTGAAGATTATGTTCAGCTTGGACAGTATGAAAACATATCAGTCCAGGTAGATAAAACTTCAATAGAGA
ATGAACTTATAGAGAGTAAAATTAAACAGGATGTAGAAGATAATACTACTTATACAGAAGTTGACAGAGGTGCGATAGCT
TCTGATCAGATTCTTGTTACATATACTGCTACATCTTCAGGCGCATCTCTTAGCGGACTTACTAATACAGATGGTAAAAC
AATGATTCTTGGAACGGATACTCTCGGACTTGAACTTGATGAGTTAGATCAGGCTTTATATGGTATGACCCCAGGTCAGA
CAAAGATACTTATTGTTGATATACCTGAGGATTATAGTTCGGATTTATATAAGGGCACGAGGGTTGTATTTGAACTTACA
ATGCAGACAGTTGCACAGGCAAATGTTCCAATGATAACTAATGCATATGTTAAGGAAGCGTTTGGATATGATACCGTTGA
AGAATATAGACAGTCAATAAAGGAATCTCTTGAAACTGATATTAATTCAAAGGTTGAGAACAAGATACAGGAAGATGTAT
TATCTTCTTTACAGGATACATTCAAGATAAGCAGTTATCCTGATTCACTTATGGAAGAAACAAGATCCAGACTTGAAACA
TCTATTGGTTTCTATGCGGATTTTTCAAATCTTTCAAAGGATGAATACTGTCAGAAGCAGTATGGACTTTCTTTTGATGA
CTTTGTTAAGAAATCTGTTGTACAGCAGCTTATCATGGAGGCTATAGTTAAAGACCGCAATATGACAATGAGAGAATACG
ATTATAAAGGTTCTCTTGATGATTTTGCGGCAGATAATGGATATTCTAATGCGGATACATTTGTTGAAAAATTCGGAAAA
GATAAGATTGTAAAGGCTATGCTTGTGCAGAAGGCACAGGATTATGTTATTGAGCATGCCAATATTTCTTATAAGTAA

Upstream 100 bases:

>100_bases
GGATAAAATGTCTTTTATATGGTATATTATGAAAGTCAATTTTTTACTTCTATATAATATAATGAAGTAAGAGCGGAGGT
TTATTGTGAAAAAAAGTTTT

Downstream 100 bases:

>100_bases
GGCAAGAAAGAATTTAGGTTGTGAGTGGGAACCGGCAGCATATTATTATGCTGCCGGTTCCTGTATTATTTTGTGCCTGT
TGAGCCAAAGCCGCCTTCGC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKKTAVALLSVSMLMVTACNSKIDVKYDYNVEDYVQLGQYENISVQVDKTSIENELIESKIKQDVEDNTTYTEVDRGAIA
SDQILVTYTATSSGASLSGLTNTDGKTMILGTDTLGLELDELDQALYGMTPGQTKILIVDIPEDYSSDLYKGTRVVFELT
MQTVAQANVPMITNAYVKEAFGYDTVEEYRQSIKESLETDINSKVENKIQEDVLSSLQDTFKISSYPDSLMEETRSRLET
SIGFYADFSNLSKDEYCQKQYGLSFDDFVKKSVVQQLIMEAIVKDRNMTMREYDYKGSLDDFAADNGYSNADTFVEKFGK
DKIVKAMLVQKAQDYVIEHANISYK

Sequences:

>Translated_345_residues
MKKTAVALLSVSMLMVTACNSKIDVKYDYNVEDYVQLGQYENISVQVDKTSIENELIESKIKQDVEDNTTYTEVDRGAIA
SDQILVTYTATSSGASLSGLTNTDGKTMILGTDTLGLELDELDQALYGMTPGQTKILIVDIPEDYSSDLYKGTRVVFELT
MQTVAQANVPMITNAYVKEAFGYDTVEEYRQSIKESLETDINSKVENKIQEDVLSSLQDTFKISSYPDSLMEETRSRLET
SIGFYADFSNLSKDEYCQKQYGLSFDDFVKKSVVQQLIMEAIVKDRNMTMREYDYKGSLDDFAADNGYSNADTFVEKFGK
DKIVKAMLVQKAQDYVIEHANISYK
>Mature_345_residues
MKKTAVALLSVSMLMVTACNSKIDVKYDYNVEDYVQLGQYENISVQVDKTSIENELIESKIKQDVEDNTTYTEVDRGAIA
SDQILVTYTATSSGASLSGLTNTDGKTMILGTDTLGLELDELDQALYGMTPGQTKILIVDIPEDYSSDLYKGTRVVFELT
MQTVAQANVPMITNAYVKEAFGYDTVEEYRQSIKESLETDINSKVENKIQEDVLSSLQDTFKISSYPDSLMEETRSRLET
SIGFYADFSNLSKDEYCQKQYGLSFDDFVKKSVVQQLIMEAIVKDRNMTMREYDYKGSLDDFAADNGYSNADTFVEKFGK
DKIVKAMLVQKAQDYVIEHANISYK

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 38832; Mature: 38832

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTAVALLSVSMLMVTACNSKIDVKYDYNVEDYVQLGQYENISVQVDKTSIENELIESK
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCCCEEEEEEHHHHHHHHHHHH
IKQDVEDNTTYTEVDRGAIASDQILVTYTATSSGASLSGLTNTDGKTMILGTDTLGLELD
HHHHHCCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCHH
ELDQALYGMTPGQTKILIVDIPEDYSSDLYKGTRVVFELTMQTVAQANVPMITNAYVKEA
HHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
FGYDTVEEYRQSIKESLETDINSKVENKIQEDVLSSLQDTFKISSYPDSLMEETRSRLET
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
SIGFYADFSNLSKDEYCQKQYGLSFDDFVKKSVVQQLIMEAIVKDRNMTMREYDYKGSLD
HHHHEECHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCH
DFAADNGYSNADTFVEKFGKDKIVKAMLVQKAQDYVIEHANISYK
HHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKTAVALLSVSMLMVTACNSKIDVKYDYNVEDYVQLGQYENISVQVDKTSIENELIESK
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCCCEEEEEEHHHHHHHHHHHH
IKQDVEDNTTYTEVDRGAIASDQILVTYTATSSGASLSGLTNTDGKTMILGTDTLGLELD
HHHHHCCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCHH
ELDQALYGMTPGQTKILIVDIPEDYSSDLYKGTRVVFELTMQTVAQANVPMITNAYVKEA
HHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
FGYDTVEEYRQSIKESLETDINSKVENKIQEDVLSSLQDTFKISSYPDSLMEETRSRLET
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
SIGFYADFSNLSKDEYCQKQYGLSFDDFVKKSVVQQLIMEAIVKDRNMTMREYDYKGSLD
HHHHEECHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCH
DFAADNGYSNADTFVEKFGKDKIVKAMLVQKAQDYVIEHANISYK
HHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA