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The map label for this gene is slyD [C]

Identifier: 238922235

GI number: 238922235

Start: 433209

End: 434123

Strand: Reverse

Name: slyD [C]

Synonym: EUBELI_20470

Alternate gene names: 238922235

Gene position: 434123-433209 (Counterclockwise)

Preceding gene: 238922236

Following gene: 238922233

Centisome position: 69.27

GC content: 42.95

Gene sequence:

>915_bases
ATGAAAATAGCAGTAACATACGAGAATGGTCAGATTTTTCAGCATTTCGGACATTCTGAGAGCTTTAAGATTTATGAGGC
AGAAGGAAAGAATATTGTCCGTGCAGAGGTAATTGGCACTGATGGAGCTGGTCATAGCGCATTGGCAGCTGTTCTTAAGG
ATAAAGGTGTAGATGTTCTTATATGTGGCGGAATCGGTAACGGTGCAGTCACAGCACTTTCAGAAGCTGGAATTGATGTA
TATTCAGGAGCAGATGGAGAAGCAGATGCAGCAGTTGAGGCATATCTTAATGGCGATTTAACATCAGCAGGAGTTAATTG
CGACCATCATCACGATCATGAAGAAGGTCATGGCTGCGGACACTGTGGAAGCCATGAAGATGAAGAGTCAGGTTGCGGAC
ATTGTGGAAGTGATGAAGGTGAATCAGACTGTGGTAGTGGTTGTGGCGGCTGCAGCGGTGGCTGTGGTACATTTACACCA
TCATTTGAAGGACCTAATGTAGGAAAGAAGGTAAAGGTTCATTATAAAGGAACACTTAACGATGGAACACAGTTTGATTC
TTCTTACGACAGAGGTGAACCGCTTGAATTTACTTGTGGAGCAGGAATGATGATTCAGGGCTTTGACAAGGCTGTTGCTA
CAATGAATGTCGGAGATGTTATTGATGTTCATCTTATGCCAGAGGAGGCGTATGGCGAAGCTGATCCAAGAGCTTTCATA
ACGTTGCCTATAAGCGAGCTTCCTGGGGCAGAAGAACTTAAAGTTGATGATAAAGTATATCTTCAGAATATGTATGGACA
GCCATTCCCAGCAAGGGTTGCTGCTTTAACTGATACAGATATCACATTTGACGCTAATCATGAGATGGCAGGAAAAGAAC
TGAATTTCAGGATAGAGCTTGTTGAAGTATTATAA

Upstream 100 bases:

>100_bases
ATGCAAATGGAGCAGTGGATATTGAATTTTAGTTATTTAAGATTTTGAAATAATTTTTCATATGTTGTATGAGAATAAAT
ATTAATCAGGAGGATTATTA

Downstream 100 bases:

>100_bases
TTGAATAATATTAAGATACCGGCTGATACATCTAAATGCAGTATCAGCCGGTTATTTTATTGTCTGGAAACAAGCTCTTT
AGTCAACCGTATCCATTCTT

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKIAVTYENGQIFQHFGHSESFKIYEAEGKNIVRAEVIGTDGAGHSALAAVLKDKGVDVLICGGIGNGAVTALSEAGIDV
YSGADGEADAAVEAYLNGDLTSAGVNCDHHHDHEEGHGCGHCGSHEDEESGCGHCGSDEGESDCGSGCGGCSGGCGTFTP
SFEGPNVGKKVKVHYKGTLNDGTQFDSSYDRGEPLEFTCGAGMMIQGFDKAVATMNVGDVIDVHLMPEEAYGEADPRAFI
TLPISELPGAEELKVDDKVYLQNMYGQPFPARVAALTDTDITFDANHEMAGKELNFRIELVEVL

Sequences:

>Translated_304_residues
MKIAVTYENGQIFQHFGHSESFKIYEAEGKNIVRAEVIGTDGAGHSALAAVLKDKGVDVLICGGIGNGAVTALSEAGIDV
YSGADGEADAAVEAYLNGDLTSAGVNCDHHHDHEEGHGCGHCGSHEDEESGCGHCGSDEGESDCGSGCGGCSGGCGTFTP
SFEGPNVGKKVKVHYKGTLNDGTQFDSSYDRGEPLEFTCGAGMMIQGFDKAVATMNVGDVIDVHLMPEEAYGEADPRAFI
TLPISELPGAEELKVDDKVYLQNMYGQPFPARVAALTDTDITFDANHEMAGKELNFRIELVEVL
>Mature_304_residues
MKIAVTYENGQIFQHFGHSESFKIYEAEGKNIVRAEVIGTDGAGHSALAAVLKDKGVDVLICGGIGNGAVTALSEAGIDV
YSGADGEADAAVEAYLNGDLTSAGVNCDHHHDHEEGHGCGHCGSHEDEESGCGHCGSDEGESDCGSGCGGCSGGCGTFTP
SFEGPNVGKKVKVHYKGTLNDGTQFDSSYDRGEPLEFTCGAGMMIQGFDKAVATMNVGDVIDVHLMPEEAYGEADPRAFI
TLPISELPGAEELKVDDKVYLQNMYGQPFPARVAALTDTDITFDANHEMAGKELNFRIELVEVL

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1433

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI224809329, Length=72, Percent_Identity=50, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI224809327, Length=72, Percent_Identity=50, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4758384, Length=72, Percent_Identity=50, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI224809331, Length=72, Percent_Identity=50, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4503729, Length=72, Percent_Identity=50, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1789748, Length=133, Percent_Identity=30.8270676691729, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786211, Length=133, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561782, Length=70, Percent_Identity=48.5714285714286, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6320727, Length=67, Percent_Identity=50.7462686567164, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24655568, Length=68, Percent_Identity=51.4705882352941, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583150, Length=72, Percent_Identity=48.6111111111111, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 31946; Mature: 31946

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVTYENGQIFQHFGHSESFKIYEAEGKNIVRAEVIGTDGAGHSALAAVLKDKGVDVL
CEEEEEECCCEEEECCCCCCCEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCEE
ICGGIGNGAVTALSEAGIDVYSGADGEADAAVEAYLNGDLTSAGVNCDHHHDHEEGHGCG
EECCCCCCHHEEHHHCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
HCGSHEDEESGCGHCGSDEGESDCGSGCGGCSGGCGTFTPSFEGPNVGKKVKVHYKGTLN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECC
DGTQFDSSYDRGEPLEFTCGAGMMIQGFDKAVATMNVGDVIDVHLMPEEAYGEADPRAFI
CCCCCCCCCCCCCCEEEECCCCEEEECCCHHHEEECCCCEEEEEECCHHHCCCCCCEEEE
TLPISELPGAEELKVDDKVYLQNMYGQPFPARVAALTDTDITFDANHEMAGKELNFRIEL
EEEHHHCCCCCCEECCHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCCCEEEEEEEE
VEVL
EEEC
>Mature Secondary Structure
MKIAVTYENGQIFQHFGHSESFKIYEAEGKNIVRAEVIGTDGAGHSALAAVLKDKGVDVL
CEEEEEECCCEEEECCCCCCCEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCEE
ICGGIGNGAVTALSEAGIDVYSGADGEADAAVEAYLNGDLTSAGVNCDHHHDHEEGHGCG
EECCCCCCHHEEHHHCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
HCGSHEDEESGCGHCGSDEGESDCGSGCGGCSGGCGTFTPSFEGPNVGKKVKVHYKGTLN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECC
DGTQFDSSYDRGEPLEFTCGAGMMIQGFDKAVATMNVGDVIDVHLMPEEAYGEADPRAFI
CCCCCCCCCCCCCCEEEECCCCEEEECCCHHHEEECCCCEEEEEECCHHHCCCCCCEEEE
TLPISELPGAEELKVDDKVYLQNMYGQPFPARVAALTDTDITFDANHEMAGKELNFRIEL
EEEHHHCCCCCCEECCHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCCCEEEEEEEE
VEVL
EEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]