Click here to switch to the map view.

The map label for this gene is luxQ [H]

Identifier: 238922202

GI number: 238922202

Start: 401032

End: 403236

Strand: Reverse

Name: luxQ [H]

Synonym: EUBELI_20437

Alternate gene names: 238922202

Gene position: 403236-401032 (Counterclockwise)

Preceding gene: 238922203

Following gene: 238922201

Centisome position: 64.34

GC content: 36.73

Gene sequence:

>2205_bases
ATGGAAAATAATACCATTACCAGAAAGAAAAGAAAAAGAATATGGCCGATTGAGATTATAGCAGGCCTGTTTATAATGAT
GATTGTGTTTTTTATTGCTGTAAATGTTGATATAAAAACTACACAGGAAACACTTTCAGATACTGCGCATTATATTAATG
AACAGTGCAACAGCTTTACAAGACTTAATCTTGCGTCAGAAACCAAGAGCCTGCTCAGGGTAATTGAAAGTGCGCAGCAG
ATAAAACATAATATCACATATGAGCGCAGCCTTTCAGATAAAGATATATTTACAGAAGAATTTATCAAAAAGAATATGCA
GGAATGTTATCTGACGGCAGTTATAATCATGGATTCAAAAGGTAATCTTATAGCACAGGAATATACAGATGAATATGGTG
CAGATGAGCTTAACGAATATCTTGACAGTACTTCACTTATTGATGTTGTTGATAATACTGAAAAAACATACGCAATAAGA
ATTGACTGTGAAGATGGTTCATATGTTGACCTTGCAGCATGTGGTATGGCGGATTCAAGTGGGATAGTTGTTGTTTATTA
CCACACACCGGCAGAGTATGTTAATAATTACAATCTTTCATTTACACATATATTATCAGGTTATGATGACAGGGAAGATG
GAAAGATTGTTGTTACAAAGGGAAATCAGATAATAGCGTCTAATGATGACAGTATGGTTGGTGAAGATATTGATAAATAT
AATGTTATTAAGAAGATAAAGGAGACTGGTGCAAGTGGCAAAATAGTACATGCTGATAGTAACAGAAGGTGGGGTTCACA
TAATTATGGTCTTATGGAACGTGGGAGAGATTATTATGTGTATGTTTATATGCCGGAAAGAAATGTTTTTAAGACAACAC
CAAGAAATATGCAGTATACATTTGTTGCCTATATGTTTGCTGTACTTGTACTTAATATGATGCGCTGGAAAACGGTTCAG
GGATATGAGCGTGAACAGTATGAAATGCAGCAGCAGTATGCAAAGACACTGCAGGAAAAAAATGAACAGCTACAGGAGGC
AGTACGCCGAGAGGAAAAGGCTAATGCTGCCAAGACTGATTTCTTATCAAGAATGACACATGATATAAGGACGCCGCTTA
ATGGCATAATCGGATTGTTAAGAATTGATGAGAGCCATAAAGAAGATACAGATATGATTAATACTAACAGAAAGAAAATG
TCAATAGCTGCTAATCATCTTTTATCACTTATTAATGACATTCTCCAGATGAGTAAGTTAGAGGATGGCCAGATTGAGCT
TTCAAGAGAGATTGTGGATCTTAACAAGCTTGCAAAGGATATTATTACTATAGTTGAACAGCGTGCCTCAGATTCAGGTG
TCAATCTTAAGTATGACAAGGTGGCAGGAAAAGTTATGTATCCATATGTATACGGAAGTCCTCTGCATTTACGCCAGTTA
TTTCTAAATATATACGCTAACTGCATCAAATATAATAAAGCAGGAGGAATGGTTTCAACATATTTTAAATGTATTGGAAC
ACAGGATGGAATTGTTACATATGAATGGACTGTTACTGATACGGGAATTGGCATGAGTGAAGAATTTCTTGAACATATAT
TTGAACCATTTGTACAGGAAAAGACAGATGCCAGAAGTGTTTATCAGGGAACAGGACTTGGTATGGCTATTGTTAAGAGT
CTGGTTGACAAAATGAATGGAACAATTAGTGTCACAAGCAAGGAAGGGGAAGGCTCAACATTTGTAATCAGAATTCCTTT
CGAGATTGCAAGCAAAGTTGAAGAAATAACGGATGATAAGGAAAAGAGCAGTAATGATATTTCGGGAATTAAGATTCTGC
TAGCAGAGGATAATGAACTTAATGCTGAGATTGCACAGACTCTTCTGGTGGATGAAGGCGCTAATGTTACTGTTGTCAGT
GATGGTGAGCAGGCTGTCAGGGAATTTACAAGGTGTGCACCACATACATATGATGTGATTCTTATGGATATTATGATGCC
AAAGCTTGACGGAATTGCCGCAACAAAAGCTATAAGAGCTATGGAAAGACCTGATGCTGTGGAGATTCCGATAATTGCAA
TGACAGCCAATGCATTTGAGGAGGATGCCAGAAAATGTGTTGAAGCCGGAATGAATGCACATCTGTCGAAGCCTTTACAG
ATGGATGTTGTAGTTGGTACAATTGCAGAGTATTATAAAAGATAA

Upstream 100 bases:

>100_bases
CTTACAGAAATTCTTAACCAGATGAGAAATGATGGTACAGAGAAGAAGATAATCAGCAGATATATTCCTGATGCTGATAA
ATATCTGGAGGTGGACAGTT

Downstream 100 bases:

>100_bases
TTATGCAGGATAAAGGAGCCTCTGCATAATACAATAACTGATAAAAGGGGATAGCTATGATATGTAGTAATTGTGGAGCA
GATATAGGAGATAACGAGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 734; Mature: 734

Protein sequence:

>734_residues
MENNTITRKKRKRIWPIEIIAGLFIMMIVFFIAVNVDIKTTQETLSDTAHYINEQCNSFTRLNLASETKSLLRVIESAQQ
IKHNITYERSLSDKDIFTEEFIKKNMQECYLTAVIIMDSKGNLIAQEYTDEYGADELNEYLDSTSLIDVVDNTEKTYAIR
IDCEDGSYVDLAACGMADSSGIVVVYYHTPAEYVNNYNLSFTHILSGYDDREDGKIVVTKGNQIIASNDDSMVGEDIDKY
NVIKKIKETGASGKIVHADSNRRWGSHNYGLMERGRDYYVYVYMPERNVFKTTPRNMQYTFVAYMFAVLVLNMMRWKTVQ
GYEREQYEMQQQYAKTLQEKNEQLQEAVRREEKANAAKTDFLSRMTHDIRTPLNGIIGLLRIDESHKEDTDMINTNRKKM
SIAANHLLSLINDILQMSKLEDGQIELSREIVDLNKLAKDIITIVEQRASDSGVNLKYDKVAGKVMYPYVYGSPLHLRQL
FLNIYANCIKYNKAGGMVSTYFKCIGTQDGIVTYEWTVTDTGIGMSEEFLEHIFEPFVQEKTDARSVYQGTGLGMAIVKS
LVDKMNGTISVTSKEGEGSTFVIRIPFEIASKVEEITDDKEKSSNDISGIKILLAEDNELNAEIAQTLLVDEGANVTVVS
DGEQAVREFTRCAPHTYDVILMDIMMPKLDGIAATKAIRAMERPDAVEIPIIAMTANAFEEDARKCVEAGMNAHLSKPLQ
MDVVVGTIAEYYKR

Sequences:

>Translated_734_residues
MENNTITRKKRKRIWPIEIIAGLFIMMIVFFIAVNVDIKTTQETLSDTAHYINEQCNSFTRLNLASETKSLLRVIESAQQ
IKHNITYERSLSDKDIFTEEFIKKNMQECYLTAVIIMDSKGNLIAQEYTDEYGADELNEYLDSTSLIDVVDNTEKTYAIR
IDCEDGSYVDLAACGMADSSGIVVVYYHTPAEYVNNYNLSFTHILSGYDDREDGKIVVTKGNQIIASNDDSMVGEDIDKY
NVIKKIKETGASGKIVHADSNRRWGSHNYGLMERGRDYYVYVYMPERNVFKTTPRNMQYTFVAYMFAVLVLNMMRWKTVQ
GYEREQYEMQQQYAKTLQEKNEQLQEAVRREEKANAAKTDFLSRMTHDIRTPLNGIIGLLRIDESHKEDTDMINTNRKKM
SIAANHLLSLINDILQMSKLEDGQIELSREIVDLNKLAKDIITIVEQRASDSGVNLKYDKVAGKVMYPYVYGSPLHLRQL
FLNIYANCIKYNKAGGMVSTYFKCIGTQDGIVTYEWTVTDTGIGMSEEFLEHIFEPFVQEKTDARSVYQGTGLGMAIVKS
LVDKMNGTISVTSKEGEGSTFVIRIPFEIASKVEEITDDKEKSSNDISGIKILLAEDNELNAEIAQTLLVDEGANVTVVS
DGEQAVREFTRCAPHTYDVILMDIMMPKLDGIAATKAIRAMERPDAVEIPIIAMTANAFEEDARKCVEAGMNAHLSKPLQ
MDVVVGTIAEYYKR
>Mature_734_residues
MENNTITRKKRKRIWPIEIIAGLFIMMIVFFIAVNVDIKTTQETLSDTAHYINEQCNSFTRLNLASETKSLLRVIESAQQ
IKHNITYERSLSDKDIFTEEFIKKNMQECYLTAVIIMDSKGNLIAQEYTDEYGADELNEYLDSTSLIDVVDNTEKTYAIR
IDCEDGSYVDLAACGMADSSGIVVVYYHTPAEYVNNYNLSFTHILSGYDDREDGKIVVTKGNQIIASNDDSMVGEDIDKY
NVIKKIKETGASGKIVHADSNRRWGSHNYGLMERGRDYYVYVYMPERNVFKTTPRNMQYTFVAYMFAVLVLNMMRWKTVQ
GYEREQYEMQQQYAKTLQEKNEQLQEAVRREEKANAAKTDFLSRMTHDIRTPLNGIIGLLRIDESHKEDTDMINTNRKKM
SIAANHLLSLINDILQMSKLEDGQIELSREIVDLNKLAKDIITIVEQRASDSGVNLKYDKVAGKVMYPYVYGSPLHLRQL
FLNIYANCIKYNKAGGMVSTYFKCIGTQDGIVTYEWTVTDTGIGMSEEFLEHIFEPFVQEKTDARSVYQGTGLGMAIVKS
LVDKMNGTISVTSKEGEGSTFVIRIPFEIASKVEEITDDKEKSSNDISGIKILLAEDNELNAEIAQTLLVDEGANVTVVS
DGEQAVREFTRCAPHTYDVILMDIMMPKLDGIAATKAIRAMERPDAVEIPIIAMTANAFEEDARKCVEAGMNAHLSKPLQ
MDVVVGTIAEYYKR

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=387, Percent_Identity=30.2325581395349, Blast_Score=173, Evalue=4e-44,
Organism=Escherichia coli, GI1788713, Length=389, Percent_Identity=28.7917737789203, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI87081816, Length=418, Percent_Identity=27.9904306220096, Blast_Score=151, Evalue=2e-37,
Organism=Escherichia coli, GI1789149, Length=431, Percent_Identity=26.9141531322506, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI145693157, Length=345, Percent_Identity=29.5652173913043, Blast_Score=126, Evalue=6e-30,
Organism=Escherichia coli, GI1790436, Length=249, Percent_Identity=29.718875502008, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1786783, Length=243, Percent_Identity=27.5720164609054, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786912, Length=270, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788393, Length=262, Percent_Identity=26.7175572519084, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=28.4518828451883, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789808, Length=237, Percent_Identity=27.0042194092827, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=24.7011952191235, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=23.109243697479, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=165, Percent_Identity=36.3636363636364, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322000, Length=125, Percent_Identity=36.8, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83231; Mature: 83231

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNTITRKKRKRIWPIEIIAGLFIMMIVFFIAVNVDIKTTQETLSDTAHYINEQCNSFT
CCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHCCCE
RLNLASETKSLLRVIESAQQIKHNITYERSLSDKDIFTEEFIKKNMQECYLTAVIIMDSK
EEEEHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHEEEEEEEECCC
GNLIAQEYTDEYGADELNEYLDSTSLIDVVDNTEKTYAIRIDCEDGSYVDLAACGMADSS
CCEEHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCC
GIVVVYYHTPAEYVNNYNLSFTHILSGYDDREDGKIVVTKGNQIIASNDDSMVGEDIDKY
CEEEEEEECCHHHHCCCCCEEEHHHCCCCCCCCCEEEEEECCEEEECCCCCCCCCCHHHH
NVIKKIKETGASGKIVHADSNRRWGSHNYGLMERGRDYYVYVYMPERNVFKTTPRNMQYT
HHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHCCCEEEEEEEECCCCCEECCCCCCHHH
FVAYMFAVLVLNMMRWKTVQGYEREQYEMQQQYAKTLQEKNEQLQEAVRREEKANAAKTD
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
FLSRMTHDIRTPLNGIIGLLRIDESHKEDTDMINTNRKKMSIAANHLLSLINDILQMSKL
HHHHHHHHHHCCHHHHHEEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
EDGQIELSREIVDLNKLAKDIITIVEQRASDSGVNLKYDKVAGKVMYPYVYGSPLHLRQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEECEEECCHHHHHHH
FLNIYANCIKYNKAGGMVSTYFKCIGTQDGIVTYEWTVTDTGIGMSEEFLEHIFEPFVQE
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHC
KTDARSVYQGTGLGMAIVKSLVDKMNGTISVTSKEGEGSTFVIRIPFEIASKVEEITDDK
CHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECHHHHHHHHHHCCCH
EKSSNDISGIKILLAEDNELNAEIAQTLLVDEGANVTVVSDGEQAVREFTRCAPHTYDVI
HCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCHHHHH
LMDIMMPKLDGIAATKAIRAMERPDAVEIPIIAMTANAFEEDARKCVEAGMNAHLSKPLQ
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCC
MDVVVGTIAEYYKR
HHHHHHHHHHHHCC
>Mature Secondary Structure
MENNTITRKKRKRIWPIEIIAGLFIMMIVFFIAVNVDIKTTQETLSDTAHYINEQCNSFT
CCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHCCCE
RLNLASETKSLLRVIESAQQIKHNITYERSLSDKDIFTEEFIKKNMQECYLTAVIIMDSK
EEEEHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHEEEEEEEECCC
GNLIAQEYTDEYGADELNEYLDSTSLIDVVDNTEKTYAIRIDCEDGSYVDLAACGMADSS
CCEEHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCC
GIVVVYYHTPAEYVNNYNLSFTHILSGYDDREDGKIVVTKGNQIIASNDDSMVGEDIDKY
CEEEEEEECCHHHHCCCCCEEEHHHCCCCCCCCCEEEEEECCEEEECCCCCCCCCCHHHH
NVIKKIKETGASGKIVHADSNRRWGSHNYGLMERGRDYYVYVYMPERNVFKTTPRNMQYT
HHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHCCCEEEEEEEECCCCCEECCCCCCHHH
FVAYMFAVLVLNMMRWKTVQGYEREQYEMQQQYAKTLQEKNEQLQEAVRREEKANAAKTD
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
FLSRMTHDIRTPLNGIIGLLRIDESHKEDTDMINTNRKKMSIAANHLLSLINDILQMSKL
HHHHHHHHHHCCHHHHHEEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
EDGQIELSREIVDLNKLAKDIITIVEQRASDSGVNLKYDKVAGKVMYPYVYGSPLHLRQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEECEEECCHHHHHHH
FLNIYANCIKYNKAGGMVSTYFKCIGTQDGIVTYEWTVTDTGIGMSEEFLEHIFEPFVQE
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHC
KTDARSVYQGTGLGMAIVKSLVDKMNGTISVTSKEGEGSTFVIRIPFEIASKVEEITDDK
CHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECHHHHHHHHHHCCCH
EKSSNDISGIKILLAEDNELNAEIAQTLLVDEGANVTVVSDGEQAVREFTRCAPHTYDVI
HCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCHHHHH
LMDIMMPKLDGIAATKAIRAMERPDAVEIPIIAMTANAFEEDARKCVEAGMNAHLSKPLQ
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCC
MDVVVGTIAEYYKR
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]