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The map label for this gene is uvrX [H]

Identifier: 238922170

GI number: 238922170

Start: 363472

End: 364839

Strand: Reverse

Name: uvrX [H]

Synonym: EUBELI_20405

Alternate gene names: 238922170

Gene position: 364839-363472 (Counterclockwise)

Preceding gene: 238922171

Following gene: 238922169

Centisome position: 58.21

GC content: 38.52

Gene sequence:

>1368_bases
ATGGAAAGAGTGTATATTGCAATTGATCTTAAATCATTCTATGCAAGTGTTGAGTGTGTTGAAAGAGAATCAGACCCGCT
TACCACTAATCTCGTTGTAGCTGATGAATCAAGAACAGCCAAAACAATATGTCTTGCAGTTACTCCTTCTCTTAAGAAAT
ATGGACTTTCCGGACGAAGCAGGCTTTTTGAGGTAGAACAGAAGGCAAAAGAAATAGAGAAACGCACAGGAAAAAAGCTT
GAATATATAGTAGCAGTTCCAAGAATGGGGCTTTATATAGAATATTCATCAAAGATATATTCTATATACCTTAAATATTT
CAGCAAGGATGACATAACTGTATACAGTATTGATGAAGTATTTATTGATGCAACGGATTATATGAAGCTGTATAATATGA
CAGCAAGACAGCTTACCGCAAAAGTTATAGAGGATGTGTATGATACGACAGGGATAACGGCTACGGCAGGAATTGCACCT
AATCTGTATCTGTGCAAGATAGCAATGGATATAGTTGCAAAGCATATACAGGCAGACAGCAAGGGCGTGCGTATCGCAGA
ATTAAGTGTTAATGATTACAGAAAAATGTTATGGGGTCATACACCTCTTACTGACTTCTGGAGGGTTGGACCAGGAATAT
CAAGACAGCTTGAAAAACATGGGATAAAGACTATGGGTGATATTGCGAGAATGTCCCTTGAAGATGAGGACTGGCTGTAT
AAGCAGTTTGGTGTAGACGCAGAGATTCTTATAGACCACGCATGGGGATATGAACCGTGTACAATTGCAGATATTAAGAA
ATATAAGCCCAAGGCGAGCAGCCTGTGTTCAGGACAGGTGTTAAAAGAGCCATATACATTTGAAGACGCAAGAATTGTAG
TTGGAGAGATGGCAGATGAGCTTGCATTGGATTTAGTTGATAAAGGTTTTGTGACCGATTCGATTGCGTTAAATGTAACT
TATGACAGGGTAAATGTTGATAAAGGAACTTACAAGGGTGAAATCCATGTAGACAGATATGGAAGGGAAGTTCCACAAGG
ACTTAATAAATCTGTTTCACTTACGACATGTACATCTTCATCAAAACAGTTAAGAGAAGCTTTTCTTGATATATATGACA
AATATACTGACAGAAAGCTGTATATCCGAAAGTTAAATCTTACAGTTGCCAATCTTACTAATGATGGTTTTCAACAGTTT
GACATGTTTACAGACCAGACACAGCTTGAACGCGAAAAGAAGATGCAGCATGCAATGCTTGATATTAAGAAAAAATACGG
TAAGAATGCGGTGATGAAAGCTAATAATCTGCAGAGCAAAGCGACTGCAATTGAAAGGAACGGGCAGATAGGAGGTCACA
GGGCATAG

Upstream 100 bases:

>100_bases
GAATATTGCAATGAAAATTGGCTAGAATTATTATGAAACTACAAGACACACTGGTATATGCTGGTGTGTCTTTTTCTAGG
ATTAAGTATAGGAGGATGTA

Downstream 100 bases:

>100_bases
CTTATGGGAAAATATGATGATATAATCAATATGAAATGGCCGGTGCCGAGTAAAAGACCAAGAATGGATATGGAAAGCAG
GGCTAAGATATTCCTTCCTT

Product: DNA polymerase V

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MERVYIAIDLKSFYASVECVERESDPLTTNLVVADESRTAKTICLAVTPSLKKYGLSGRSRLFEVEQKAKEIEKRTGKKL
EYIVAVPRMGLYIEYSSKIYSIYLKYFSKDDITVYSIDEVFIDATDYMKLYNMTARQLTAKVIEDVYDTTGITATAGIAP
NLYLCKIAMDIVAKHIQADSKGVRIAELSVNDYRKMLWGHTPLTDFWRVGPGISRQLEKHGIKTMGDIARMSLEDEDWLY
KQFGVDAEILIDHAWGYEPCTIADIKKYKPKASSLCSGQVLKEPYTFEDARIVVGEMADELALDLVDKGFVTDSIALNVT
YDRVNVDKGTYKGEIHVDRYGREVPQGLNKSVSLTTCTSSSKQLREAFLDIYDKYTDRKLYIRKLNLTVANLTNDGFQQF
DMFTDQTQLEREKKMQHAMLDIKKKYGKNAVMKANNLQSKATAIERNGQIGGHRA

Sequences:

>Translated_455_residues
MERVYIAIDLKSFYASVECVERESDPLTTNLVVADESRTAKTICLAVTPSLKKYGLSGRSRLFEVEQKAKEIEKRTGKKL
EYIVAVPRMGLYIEYSSKIYSIYLKYFSKDDITVYSIDEVFIDATDYMKLYNMTARQLTAKVIEDVYDTTGITATAGIAP
NLYLCKIAMDIVAKHIQADSKGVRIAELSVNDYRKMLWGHTPLTDFWRVGPGISRQLEKHGIKTMGDIARMSLEDEDWLY
KQFGVDAEILIDHAWGYEPCTIADIKKYKPKASSLCSGQVLKEPYTFEDARIVVGEMADELALDLVDKGFVTDSIALNVT
YDRVNVDKGTYKGEIHVDRYGREVPQGLNKSVSLTTCTSSSKQLREAFLDIYDKYTDRKLYIRKLNLTVANLTNDGFQQF
DMFTDQTQLEREKKMQHAMLDIKKKYGKNAVMKANNLQSKATAIERNGQIGGHRA
>Mature_455_residues
MERVYIAIDLKSFYASVECVERESDPLTTNLVVADESRTAKTICLAVTPSLKKYGLSGRSRLFEVEQKAKEIEKRTGKKL
EYIVAVPRMGLYIEYSSKIYSIYLKYFSKDDITVYSIDEVFIDATDYMKLYNMTARQLTAKVIEDVYDTTGITATAGIAP
NLYLCKIAMDIVAKHIQADSKGVRIAELSVNDYRKMLWGHTPLTDFWRVGPGISRQLEKHGIKTMGDIARMSLEDEDWLY
KQFGVDAEILIDHAWGYEPCTIADIKKYKPKASSLCSGQVLKEPYTFEDARIVVGEMADELALDLVDKGFVTDSIALNVT
YDRVNVDKGTYKGEIHVDRYGREVPQGLNKSVSLTTCTSSSKQLREAFLDIYDKYTDRKLYIRKLNLTVANLTNDGFQQF
DMFTDQTQLEREKKMQHAMLDIKKKYGKNAVMKANNLQSKATAIERNGQIGGHRA

Specific function: Involved In Uv Protection And Mutation. Essential For Induced (Or Sos) Mutagenesis. May Modify The DNA Replication Machinery To Allow Bypass Synthesis Across A Damaged Template. [C]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=431, Percent_Identity=22.969837587007, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786425, Length=260, Percent_Identity=26.1538461538462, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 51701; Mature: 51701

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVYIAIDLKSFYASVECVERESDPLTTNLVVADESRTAKTICLAVTPSLKKYGLSGRS
CCEEEEEEEHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCHHHHCCCCHH
RLFEVEQKAKEIEKRTGKKLEYIVAVPRMGLYIEYSSKIYSIYLKYFSKDDITVYSIDEV
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCEEEHHHHHHCCCCEEEEEEHHE
FIDATDYMKLYNMTARQLTAKVIEDVYDTTGITATAGIAPNLYLCKIAMDIVAKHIQADS
EECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCC
KGVRIAELSVNDYRKMLWGHTPLTDFWRVGPGISRQLEKHGIKTMGDIARMSLEDEDWLY
CCCEEEEECHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCCHHHH
KQFGVDAEILIDHAWGYEPCTIADIKKYKPKASSLCSGQVLKEPYTFEDARIVVGEMADE
HHHCCCCEEEEECCCCCCCCCHHHHHHCCCCHHHCCCCCHHCCCCCCCCCEEEEHHHHHH
LALDLVDKGFVTDSIALNVTYDRVNVDKGTYKGEIHVDRYGREVPQGLNKSVSLTTCTSS
HHHHHHHCCCEECEEEEEEEEEEEECCCCCEECEEEEHHHCCHHHHCCCCCEEEEEECCC
SKQLREAFLDIYDKYTDRKLYIRKLNLTVANLTNDGFQQFDMFTDQTQLEREKKMQHAML
HHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHH
DIKKKYGKNAVMKANNLQSKATAIERNGQIGGHRA
HHHHHHCCCCEEECCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MERVYIAIDLKSFYASVECVERESDPLTTNLVVADESRTAKTICLAVTPSLKKYGLSGRS
CCEEEEEEEHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCHHHHCCCCHH
RLFEVEQKAKEIEKRTGKKLEYIVAVPRMGLYIEYSSKIYSIYLKYFSKDDITVYSIDEV
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCEEEHHHHHHCCCCEEEEEEHHE
FIDATDYMKLYNMTARQLTAKVIEDVYDTTGITATAGIAPNLYLCKIAMDIVAKHIQADS
EECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCC
KGVRIAELSVNDYRKMLWGHTPLTDFWRVGPGISRQLEKHGIKTMGDIARMSLEDEDWLY
CCCEEEEECHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCCHHHH
KQFGVDAEILIDHAWGYEPCTIADIKKYKPKASSLCSGQVLKEPYTFEDARIVVGEMADE
HHHCCCCEEEEECCCCCCCCCHHHHHHCCCCHHHCCCCCHHCCCCCCCCCEEEEHHHHHH
LALDLVDKGFVTDSIALNVTYDRVNVDKGTYKGEIHVDRYGREVPQGLNKSVSLTTCTSS
HHHHHHHCCCEECEEEEEEEEEEEECCCCCEECEEEEHHHCCHHHHCCCCCEEEEEECCC
SKQLREAFLDIYDKYTDRKLYIRKLNLTVANLTNDGFQQFDMFTDQTQLEREKKMQHAML
HHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHH
DIKKKYGKNAVMKANNLQSKATAIERNGQIGGHRA
HHHHHHCCCCEEECCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]