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The map label for this gene is alr2 [H]

Identifier: 238922140

GI number: 238922140

Start: 331536

End: 332705

Strand: Reverse

Name: alr2 [H]

Synonym: EUBELI_20375

Alternate gene names: 238922140

Gene position: 332705-331536 (Counterclockwise)

Preceding gene: 238922148

Following gene: 238922139

Centisome position: 53.08

GC content: 37.86

Gene sequence:

>1170_bases
ATGGATTCAACATTAAGAAGAACATGGGCTGAAATAGATATGGATGCACTTGCACATAATTATGAAACATTACGGAAAAG
AATTGGAGAAAATGTTAAGTTTTTAGGCGTTGTAAAAGCGGATGCTTACGGACATGGTTCTGTACAGGTAAGCAGACTTT
TACAGGAGTCCGGAGCAGATTATCTTGCAGTAAGCAGTATAGATGAAGCTGTAGAATTAAGACATAATGGTATTACAATG
CCGGTTCTTATACTTGGACATACACCTAAGGAAGAAGTATCTGAACTTATTAAGAATAATATAACACAGGCTGTAACATG
CAGGGCTAAGGCACTTGAATACAGTGAGGAAGCTGTTAAATGTGGTGGTACATTAAAGATTCATATTAAAGTTGATACAG
GAATGTCAAGACTTGGATATCTGTGTGACGGAGATTATTTTGAAAGTGGTGTTGAAGGAATATGTGAAGGCTGTACTCTT
CCAGGTCTTGATGCTGAGGGAATATTCACACATTTTGCAGTATCTGATGAATTTGGAGAAGAATATGAAAGCTATACTAA
GCATCAGTTTGAATTGTTTACCAGTGTGATTGATGAAGTTGAGAAAAAACTTGGAAAGAAATTCAAGATAAGACACTGTG
CCAATACAGGTGCTGTTGCAAGATATCCTGAAACATGGCTTGACATGGTAAGACCAGGACTTCTGCTCTATGGATATGGA
GATTTTGCACAGGAGCTTGGACTTAAGCCTGTTATGTCACTTAAGACAACAGTAAGCACAATCAAGACTTACCCTGCCGG
AACAGCAATAAGCTATGGAGGAATATACAAGACTGACAGAAAGACAAGAATGGGAGTTGTTCCTTATGGATATGCTGATG
GATATTTCAGATGCCTTTCTAACAGATATGAACTTATGACAGAAGAAGGTCCTGCTCCACAGAGAGGCAAGATATGTATG
GATATGTGCATGATTGATCTTACAGATAAAATGAATGTTGACGTTGGTAGTGAAGTAGAGATATTTGGTAAGGCTAATCC
TATTGAGCATATGGCACAGCTTGCAGGAACAATTCCTTATGAGCTTACATGTGCAGTAAGTAAGCGTGTCCCTAGAATGT
ACATAAAGGATGGCAAAGTTTATGAAAAAGAATTATTGTTAAGAGGATAA

Upstream 100 bases:

>100_bases
CTATAAAATGTCAACCTAAAATTAATTTAAAAAATATTCACTAATCATCAATAAAATGGTAAAATATTAAAATATGTTTA
GATAATGGAGGCAGATTATT

Downstream 100 bases:

>100_bases
ATGAATGAAGAAAATATTATGTGTATTAATGTCCTGTTTATTGTTTGTGATGGCAGGATGTAGCGGGCATAGTAAGAATT
TGAAATTTGGTGCAGCAGAT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MDSTLRRTWAEIDMDALAHNYETLRKRIGENVKFLGVVKADAYGHGSVQVSRLLQESGADYLAVSSIDEAVELRHNGITM
PVLILGHTPKEEVSELIKNNITQAVTCRAKALEYSEEAVKCGGTLKIHIKVDTGMSRLGYLCDGDYFESGVEGICEGCTL
PGLDAEGIFTHFAVSDEFGEEYESYTKHQFELFTSVIDEVEKKLGKKFKIRHCANTGAVARYPETWLDMVRPGLLLYGYG
DFAQELGLKPVMSLKTTVSTIKTYPAGTAISYGGIYKTDRKTRMGVVPYGYADGYFRCLSNRYELMTEEGPAPQRGKICM
DMCMIDLTDKMNVDVGSEVEIFGKANPIEHMAQLAGTIPYELTCAVSKRVPRMYIKDGKVYEKELLLRG

Sequences:

>Translated_389_residues
MDSTLRRTWAEIDMDALAHNYETLRKRIGENVKFLGVVKADAYGHGSVQVSRLLQESGADYLAVSSIDEAVELRHNGITM
PVLILGHTPKEEVSELIKNNITQAVTCRAKALEYSEEAVKCGGTLKIHIKVDTGMSRLGYLCDGDYFESGVEGICEGCTL
PGLDAEGIFTHFAVSDEFGEEYESYTKHQFELFTSVIDEVEKKLGKKFKIRHCANTGAVARYPETWLDMVRPGLLLYGYG
DFAQELGLKPVMSLKTTVSTIKTYPAGTAISYGGIYKTDRKTRMGVVPYGYADGYFRCLSNRYELMTEEGPAPQRGKICM
DMCMIDLTDKMNVDVGSEVEIFGKANPIEHMAQLAGTIPYELTCAVSKRVPRMYIKDGKVYEKELLLRG
>Mature_389_residues
MDSTLRRTWAEIDMDALAHNYETLRKRIGENVKFLGVVKADAYGHGSVQVSRLLQESGADYLAVSSIDEAVELRHNGITM
PVLILGHTPKEEVSELIKNNITQAVTCRAKALEYSEEAVKCGGTLKIHIKVDTGMSRLGYLCDGDYFESGVEGICEGCTL
PGLDAEGIFTHFAVSDEFGEEYESYTKHQFELFTSVIDEVEKKLGKKFKIRHCANTGAVARYPETWLDMVRPGLLLYGYG
DFAQELGLKPVMSLKTTVSTIKTYPAGTAISYGGIYKTDRKTRMGVVPYGYADGYFRCLSNRYELMTEEGPAPQRGKICM
DMCMIDLTDKMNVDVGSEVEIFGKANPIEHMAQLAGTIPYELTCAVSKRVPRMYIKDGKVYEKELLLRG

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=371, Percent_Identity=31.5363881401617, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1787439, Length=372, Percent_Identity=29.8387096774194, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43315; Mature: 43315

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTLRRTWAEIDMDALAHNYETLRKRIGENVKFLGVVKADAYGHGSVQVSRLLQESGAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCC
YLAVSSIDEAVELRHNGITMPVLILGHTPKEEVSELIKNNITQAVTCRAKALEYSEEAVK
EEEEHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
CGGTLKIHIKVDTGMSRLGYLCDGDYFESGVEGICEGCTLPGLDAEGIFTHFAVSDEFGE
CCCEEEEEEEECCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHH
EYESYTKHQFELFTSVIDEVEKKLGKKFKIRHCANTGAVARYPETWLDMVRPGLLLYGYG
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHCCCEEEEECC
DFAQELGLKPVMSLKTTVSTIKTYPAGTAISYGGIYKTDRKTRMGVVPYGYADGYFRCLS
HHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCEECCCCCCCCHHHHHHHH
NRYELMTEEGPAPQRGKICMDMCMIDLTDKMNVDVGSEVEIFGKANPIEHMAQLAGTIPY
CHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCE
ELTCAVSKRVPRMYIKDGKVYEKELLLRG
EEEEEHHHCCCEEEECCCCEEHHHHHCCC
>Mature Secondary Structure
MDSTLRRTWAEIDMDALAHNYETLRKRIGENVKFLGVVKADAYGHGSVQVSRLLQESGAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCC
YLAVSSIDEAVELRHNGITMPVLILGHTPKEEVSELIKNNITQAVTCRAKALEYSEEAVK
EEEEHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
CGGTLKIHIKVDTGMSRLGYLCDGDYFESGVEGICEGCTLPGLDAEGIFTHFAVSDEFGE
CCCEEEEEEEECCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHH
EYESYTKHQFELFTSVIDEVEKKLGKKFKIRHCANTGAVARYPETWLDMVRPGLLLYGYG
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHCCCEEEEECC
DFAQELGLKPVMSLKTTVSTIKTYPAGTAISYGGIYKTDRKTRMGVVPYGYADGYFRCLS
HHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCEECCCCCCCCHHHHHHHH
NRYELMTEEGPAPQRGKICMDMCMIDLTDKMNVDVGSEVEIFGKANPIEHMAQLAGTIPY
CHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCE
ELTCAVSKRVPRMYIKDGKVYEKELLLRG
EEEEEHHHCCCEEEECCCCEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]