Click here to switch to the map view.

The map label for this gene is sdaAA [H]

Identifier: 238922102

GI number: 238922102

Start: 285928

End: 286827

Strand: Reverse

Name: sdaAA [H]

Synonym: EUBELI_20337

Alternate gene names: 238922102

Gene position: 286827-285928 (Counterclockwise)

Preceding gene: 238922103

Following gene: 238922101

Centisome position: 45.76

GC content: 42.0

Gene sequence:

>900_bases
GTGAAAAATGGAGGATTTATGGCAGAATATCATTCAATCAGTGACCTTGTGAAATTAAGTATTAATAATAAGCAGGAATT
ATGGCAGGTTGTTCTTACGGGACAAGCACGTGACAAGCTAATGTCTGAAAGAGATGTATTTGCACAGATGAAAAAGATGT
ATCAGGCTATGAAGAGCGCAGATGAGCAATATGACCAGCAGTTGAGGTCACCAAGTAAAATGGCTGGTGGTGATGGATAT
AAAATGCGAATTTATAATGAGTCTGGCAGAAATATATGTGGTGATTTTATTGGTGTGGTTATGGAAAAAGCATTAAAGAT
GGGGGAATCGAATGCATGCATGAAGAGAATAGTAGCAGCACCTACAGCAGGTTCATGTGGTGTTATTCCGGCTGTATTAC
TGTCTTATGAAAAATGTTTTGGCGTTACAGAAGATGAATGTGTAAAAGCGTTATTAATTGCGGCCGGAATAGGTGCGGTA
ATTGCTGAAAATGCATCTATTGCAGGAGCAGCAGGTGGCTGTCAGGCAGAGATTGGTTCGGCAAGTGCAATGGCAGCGGC
GGGACTGGCTTATATGCAGGGAGCAGATAGTGAAGGATGTGCAAATGCCCTGGCACTTGCTTTAAAGAGTATGCTGGGGC
TGACATGTGATCCGGTTTGCGGATTAGTTGAGGTTCCATGTATAAAGAGAAATGTTTCTGGGGCAGTCAATGCAATTACG
GCGGCACAGATGACAATGGCGGGTATAAAGAGCGTAATTCCTGCAGACGAGGTTATAGATTCCATGAGAAGGATAGGTAA
TGACATGCCGGTATGTCTTAAAGAAACAGGTGAAGGTGGACTGGCAATAACACCAACTGCAAAAGTGTATAAGCAAAAGT
TAAATAATATTGACAACTAA

Upstream 100 bases:

>100_bases
GGAGGGAATTAACTGGTTAAGACATGCAGAAGGTGTTGTCAAGGTGACTTATCTTGGCTTGGAATAATCATAATGTAGAA
TTTGATTAGCATAATTATTG

Downstream 100 bases:

>100_bases
TGTCACAAAAAATGACAAAAAATTGACAAAAAATACTGTTTTTTTAAAAAAAATGGCAAAAAAACTGTTGATTGACAAAA
ATAATATGCTATAATATAGA

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKNGGFMAEYHSISDLVKLSINNKQELWQVVLTGQARDKLMSERDVFAQMKKMYQAMKSADEQYDQQLRSPSKMAGGDGY
KMRIYNESGRNICGDFIGVVMEKALKMGESNACMKRIVAAPTAGSCGVIPAVLLSYEKCFGVTEDECVKALLIAAGIGAV
IAENASIAGAAGGCQAEIGSASAMAAAGLAYMQGADSEGCANALALALKSMLGLTCDPVCGLVEVPCIKRNVSGAVNAIT
AAQMTMAGIKSVIPADEVIDSMRRIGNDMPVCLKETGEGGLAITPTAKVYKQKLNNIDN

Sequences:

>Translated_299_residues
MKNGGFMAEYHSISDLVKLSINNKQELWQVVLTGQARDKLMSERDVFAQMKKMYQAMKSADEQYDQQLRSPSKMAGGDGY
KMRIYNESGRNICGDFIGVVMEKALKMGESNACMKRIVAAPTAGSCGVIPAVLLSYEKCFGVTEDECVKALLIAAGIGAV
IAENASIAGAAGGCQAEIGSASAMAAAGLAYMQGADSEGCANALALALKSMLGLTCDPVCGLVEVPCIKRNVSGAVNAIT
AAQMTMAGIKSVIPADEVIDSMRRIGNDMPVCLKETGEGGLAITPTAKVYKQKLNNIDN
>Mature_299_residues
MKNGGFMAEYHSISDLVKLSINNKQELWQVVLTGQARDKLMSERDVFAQMKKMYQAMKSADEQYDQQLRSPSKMAGGDGY
KMRIYNESGRNICGDFIGVVMEKALKMGESNACMKRIVAAPTAGSCGVIPAVLLSYEKCFGVTEDECVKALLIAAGIGAV
IAENASIAGAAGGCQAEIGSASAMAAAGLAYMQGADSEGCANALALALKSMLGLTCDPVCGLVEVPCIKRNVSGAVNAIT
AAQMTMAGIKSVIPADEVIDSMRRIGNDMPVCLKETGEGGLAITPTAKVYKQKLNNIDN

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=287, Percent_Identity=36.2369337979094, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789161, Length=182, Percent_Identity=46.1538461538462, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788116, Length=182, Percent_Identity=45.0549450549451, Blast_Score=144, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 31459; Mature: 31459

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
9.7 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
9.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNGGFMAEYHSISDLVKLSINNKQELWQVVLTGQARDKLMSERDVFAQMKKMYQAMKSA
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DEQYDQQLRSPSKMAGGDGYKMRIYNESGRNICGDFIGVVMEKALKMGESNACMKRIVAA
HHHHHHHHCCCCHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
PTAGSCGVIPAVLLSYEKCFGVTEDECVKALLIAAGIGAVIAENASIAGAAGGCQAEIGS
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCC
ASAMAAAGLAYMQGADSEGCANALALALKSMLGLTCDPVCGLVEVPCIKRNVSGAVNAIT
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHH
AAQMTMAGIKSVIPADEVIDSMRRIGNDMPVCLKETGEGGLAITPTAKVYKQKLNNIDN
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCEEECCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNGGFMAEYHSISDLVKLSINNKQELWQVVLTGQARDKLMSERDVFAQMKKMYQAMKSA
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DEQYDQQLRSPSKMAGGDGYKMRIYNESGRNICGDFIGVVMEKALKMGESNACMKRIVAA
HHHHHHHHCCCCHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
PTAGSCGVIPAVLLSYEKCFGVTEDECVKALLIAAGIGAVIAENASIAGAAGGCQAEIGS
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCC
ASAMAAAGLAYMQGADSEGCANALALALKSMLGLTCDPVCGLVEVPCIKRNVSGAVNAIT
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHH
AAQMTMAGIKSVIPADEVIDSMRRIGNDMPVCLKETGEGGLAITPTAKVYKQKLNNIDN
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCEEECCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]