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The map label for this gene is cpsD [H]

Identifier: 238922084

GI number: 238922084

Start: 269890

End: 270591

Strand: Reverse

Name: cpsD [H]

Synonym: EUBELI_20319

Alternate gene names: 238922084

Gene position: 270591-269890 (Counterclockwise)

Preceding gene: 238922085

Following gene: 238922083

Centisome position: 43.17

GC content: 36.75

Gene sequence:

>702_bases
ATGCAGGAGTTTTCAGTAAAGAAAAGTTATCTTGATTTCAGAACAAGGGAAGCATATAAAATGTTACGAACAAACATAGA
GTTCTCAGGAGATAATAATAAGGTAATATTCATAACAAGTACAACACCAGGAGAAGGTAAGAGTACAGTATCATTTGAGT
TAGCAATGTCATTTGCGCAGAACGGAATGAAGACACTTCTTATAGATGCTGATACAAGAAAATCAGTTATGAAGAACAGA
TGGAGAAAAGGTAAGATTAAATATGGTCTTACTCATTACCTTTCAGGAAAAAATGAACTTACAGATGTTATAAGCGTAAG
TGATGAGCCTAATTTCTGCATGATATTCGCAGGTCCTGTTCCTCCTAACCCAAGTGAACTGGTTGGAAATGACAGATTTG
CTGAACTGATTGAAAGTGCAAGAGAGACATTTGACATGATAATAGTTGATACACCACCAATAGGAAGTGTTATCGATGCC
GCTGTTATGTCTAAGTTCTGTGATGGCGGAATACTTGTAATAGGTGCAGGAGATATAAGCTACAAGTTCGCAAGGAAATC
CAAAGAACAGCTTGACCTTGTAGGCTGCAAGATTCTTGGATGCGTTCTTAATAAGGTTGATATGGCTGGTAATTCATATT
ACGGCAGATACTATGGCAAGTATTACGGCAAATATTATGGAAAATACGGTGAAGAAAGTTAA

Upstream 100 bases:

>100_bases
ATATCACTATGAATGATGATAAGGGAAGAAGCTTTAAGGCATCTGAACTTGAGAATAAGAAGAAAAGTAATGGTGCTAAA
GAAAGCGTGGAGGAATAAAA

Downstream 100 bases:

>100_bases
GAGCGAGGAATAACCTGTACGGAGCTGAATTTCGTTGGGAGGGGTAGAGAGAATACCTTTCTTCTTGGAGGATTTTGGCT
CCGTAGTTGTGTATATTGAT

Product: non-specific protein-tyrosine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MQEFSVKKSYLDFRTREAYKMLRTNIEFSGDNNKVIFITSTTPGEGKSTVSFELAMSFAQNGMKTLLIDADTRKSVMKNR
WRKGKIKYGLTHYLSGKNELTDVISVSDEPNFCMIFAGPVPPNPSELVGNDRFAELIESARETFDMIIVDTPPIGSVIDA
AVMSKFCDGGILVIGAGDISYKFARKSKEQLDLVGCKILGCVLNKVDMAGNSYYGRYYGKYYGKYYGKYGEES

Sequences:

>Translated_233_residues
MQEFSVKKSYLDFRTREAYKMLRTNIEFSGDNNKVIFITSTTPGEGKSTVSFELAMSFAQNGMKTLLIDADTRKSVMKNR
WRKGKIKYGLTHYLSGKNELTDVISVSDEPNFCMIFAGPVPPNPSELVGNDRFAELIESARETFDMIIVDTPPIGSVIDA
AVMSKFCDGGILVIGAGDISYKFARKSKEQLDLVGCKILGCVLNKVDMAGNSYYGRYYGKYYGKYYGKYGEES
>Mature_233_residues
MQEFSVKKSYLDFRTREAYKMLRTNIEFSGDNNKVIFITSTTPGEGKSTVSFELAMSFAQNGMKTLLIDADTRKSVMKNR
WRKGKIKYGLTHYLSGKNELTDVISVSDEPNFCMIFAGPVPPNPSELVGNDRFAELIESARETFDMIIVDTPPIGSVIDA
AVMSKFCDGGILVIGAGDISYKFARKSKEQLDLVGCKILGCVLNKVDMAGNSYYGRYYGKYYGKYYGKYGEES

Specific function: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell sur

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CpsD/CapB family [H]

Homologues:

Organism=Escherichia coli, GI1787216, Length=192, Percent_Identity=40.1041666666667, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI87082032, Length=209, Percent_Identity=32.0574162679426, Blast_Score=111, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =2.7.10.2 [H]

Molecular weight: Translated: 26045; Mature: 26045

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEFSVKKSYLDFRTREAYKMLRTNIEFSGDNNKVIFITSTTPGEGKSTVSFELAMSFAQ
CCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEECCCCCCCCEEEHHHHHHHHH
NGMKTLLIDADTRKSVMKNRWRKGKIKYGLTHYLSGKNELTDVISVSDEPNFCMIFAGPV
CCCEEEEEECCHHHHHHHHHHCCCCEEECHHEEECCCCHHHHEEEECCCCCEEEEEECCC
PPNPSELVGNDRFAELIESARETFDMIIVDTPPIGSVIDAAVMSKFCDGGILVIGAGDIS
CCCHHHHCCCHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCC
YKFARKSKEQLDLVGCKILGCVLNKVDMAGNSYYGRYYGKYYGKYYGKYGEES
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQEFSVKKSYLDFRTREAYKMLRTNIEFSGDNNKVIFITSTTPGEGKSTVSFELAMSFAQ
CCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEECCCCCCCCEEEHHHHHHHHH
NGMKTLLIDADTRKSVMKNRWRKGKIKYGLTHYLSGKNELTDVISVSDEPNFCMIFAGPV
CCCEEEEEECCHHHHHHHHHHCCCCEEECHHEEECCCCHHHHEEEECCCCCEEEEEECCC
PPNPSELVGNDRFAELIESARETFDMIIVDTPPIGSVIDAAVMSKFCDGGILVIGAGDIS
CCCHHHHCCCHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCC
YKFARKSKEQLDLVGCKILGCVLNKVDMAGNSYYGRYYGKYYGKYYGKYGEES
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10464185; 11027683 [H]